Search results for "Prospective cohort study"

Appropriateness of requests for human serum albumin at the University Hospital of Palermo, Italy: a prospective study

2015

Abstract OBJECTIVE: First, to assess the appropriateness of requests for albumin using current guidelines; second, to evaluate physicians' compliance with this protocol. DESIGN: Descriptive, prospective study. SETTING: 'Paolo Giaccone' University Hospital in Palermo (Italy). PARTICIPANTS: The six departments with the highest orders for albumin. INTERVENTION: An experimental, pharmacist-driven process for daily orders of albumin was activated over a period of 1 month. Pharmacy personnel handed out order forms on six different wards. Physicians were required to select one of a number of intended uses listed on the form. MAIN OUTCOME MEASURES: Data on albumin and serum protein levels; number o…

EVALUATION OF EXTRAPYRAMIDAL INVOLVEMENT IN AMYOTROPHIC LATERAL SCLEROSIS (ALS): A PROSPECTIVE COHORT SURVEY

Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study

2014

[Background] It is unknown whether individuals at high cardiovascular risk sustain a benefit in cardiovascular disease from increased olive oil consumption. The aim was to assess the association between total olive oil intake, its varieties (extra virgin and common olive oil) and the risk of cardiovascular disease and mortality in a Mediterranean population at high cardiovascular risk.

Cardiorespiratory Fitness and the Risk of Serious Ventricular Arrhythmias: A Prospective Cohort Study.

2019

Cardiorespiratory fitness (CRF) is an established risk factor for cardiovascular disease outcomes. However, the relationship of CRF with risk of ventricular arrhythmias (VAs) is unknown. We aimed to assess the prospective association of CRF with the risk of serious VAs. Cardiorespiratory fitness, as measured by maximal oxygen uptake, was assessed using a respiratory gas exchange analyzer in 2299 middle-aged men in the Kuopio Ischemic Heart Disease prospective cohort. We corrected for within-person variability in CRF levels using data from repeated measurements 11 years apart. During median follow-up of 25.3 years (interquartile range, 18.7-27.2 years), 73 serious VAs were recorded. The age-…

Long-term safety of nine systemic medications for psoriasis: A cohort study using the Spanish Registry of Adverse Events for Biological Therapy in De…

2020

Background: Registry studies broadly describing the safety of systemic drugs in psoriasis are needed. Objective: To describe the safety findings of the systemic drugs acitretin, adalimumab, apremilast, cyclosporine, etanercept, infliximab, methotrexate, secukinumab, and ustekinumab used for the treatment of moderate to severe psoriasis in patients included in the Spanish Registry of Adverse Events for Biological Therapy in Dermatological Diseases (BIOBADADERM) Registry. Methods: The incidence rate ratio (IRR) and adjusted IRR (including propensity scores) of identified adverse events for each drug, using methotrexate as reference, were determined by means of a prospective cohort. Results: O…

Physical fitness and anthropometrics in Finnish soldiers during their early career: prospective changes during a 3-year follow-up.

2020

IntroductionPhysical fitness is a fundamental capability required of military personnel, but studies focusing on longitudinal changes in physical fitness and anthropometrics in soldiers are lacking. The aim was to evaluate physical fitness and anthropometrics in soldiers during their early career.MethodsA 3-year prospective study included 180 male soldiers (baseline age 26±2 years) with measures of a 12 min running test, standing long jump, sit-up and push-up tests, and body mass, height and waist circumference (WC). Baseline data were stratified into tertiles, and the changes within each tertile were analysed using dependent t-tests and analysis of variance.Results12 min running test dista…