Search results for "Protein"
showing 10 items of 21431 documents
The contribution of methyl groups dynamics to the dynamical transition of proteins
2008
Immobilization of proteins in silica gel: Biochemical and biophysical properties
2015
The development of silica-based sol-gel techniques compatible with the retention of protein structure and function started more than 20 years ago, mainly for the design of biotechnological devices or biomedical applications. Silica gels are optically transparent, exhibit good mechanical stability, are manufactured with different geometries, and are easily separated from the reaction media. Biomolecules encapsulated in silica gel normally retain their structural and functional properties, are stabilized with respect to chemical and physical insults, and can sometimes exhibit enhanced activity in comparison to the soluble form. This review briefly describes the chemistry of protein encapsulat…
Investigating protein structure and dynamics through wide-angle X-ray solution scattering
2016
Wide-angle X-ray scattering (WAXS) is a powerful tool that can be used to gain information on the structure and dynamics of proteins and other biomolecules in solution. Improved methods for the calculation of WAXS patterns from available or putative protein models allow to better exploit the structural information contained in the experimental data. These methods, together with recent applications of static and time-resolved WAXS, are briefly reviewed.
Optimization of the Red Tilapia (Oreochromis spp.) Viscera Hydrolysis for Obtaining Iron-Binding Peptides and Evaluation of In Vitro Iron Bioavailabi…
2020
Iron deficiencies continue to cause significant health problems in vulnerable populations. A good strategy to combat mineral deficiency includes fortification with iron-binding peptides. This research aims to determine the optimal conditions to hydrolyze red tilapia viscera (RTV) using Alcalase 2.4 L and recovery of iron-binding protein hydrolysate. The result showed that under the optimal hydrolysis condition including pH 10, 60 °
New indole and 7-azaindole derivatives as protein kinase inhibitors
2023
Negatīvā spiediena terapijas ietekme uz organisma homeostāzi
2016
Literatūras norāda uz to, ka negatīvā spiediena brūču terapija sekmē ātrāku audu defekta dzīšanu. Šīs terapijas iespējamais blakusefekts var būt organisma proteīnu zudums. Vidējais kopējā proteīna līmenis eksudātā ir 57 g/L, bet albumīna līmenis ir 21 g/L. Terapija specifisks proteīna zudums var tikt aprēķināts reizinot seruma albumīnu ar 0.3. Literatūras datiem atbilstošu olbaltumvielu uzņemšanu, kas sastāda 1.5g/kg/dienā ir attiecīgi jāreizina ar 1.3, rezultātā iegūstot 2.0 g/kg/dienā. Oriģinālās savākšanas sistēmas tika pielietotas veiksmīgi, un laboratoriskie protokoli attiecībā pret eksudātiem tika paplašināti. Šis pētījums ir ieguldījums sarežģītā zinātnē par brūču dzīšanu, prasībām p…
Protein Interaction Networks in Health and Disease
2016
COLLOIDAL VECTORS WITH POLYAMINOACID STRUCTURE FOR ORAL RELEASE OF PEPTIDES AND PROTEINS AND METHOD FOR THEIR PRODUCTION
2008
The present invention concerns colloidal vectors with polyaminoacid structure for oral release of peptides and proteins and a method for their production. Specifically, the invention concerns systems for the release of active substances, specifically peptides and proteins, by means of their incorporation in nanoparticles, nano-aggregates or complexes based on properly derivatized synthetic polyaminoacids. These polymeric systems are proposed to release peptide drugs or proteins from oral dosage forms in an effective manner, besides increasing the physicochemical stability of proteins in liquid or solid pharmaceutical dosage forms.
Behaviour of protein carbonyl groups in trained subjects
2012
Effect of Oxidized Potato Starch on the Physicochemical Properties of Soy Protein Isolate-Based Edible Films
2013
The influence of oxidized starch on the physicochemical properties of cast soy protein isolate films is determined in this study. Films were cast from heated (70 °C for 20 min) alkaline (pH=10) aqueous solutions of 7 % soy protein isolate containing 50 % (by mass) glycerol as a plasticizer and different levels of added oxidized starch (0, 5, 10, 15, and 20 %, by mass). For all types of films, opacity, contact angle, tensile strength, elongation at break, water vapour permeability, measured at 25 °C for four relative humidity differentials (30–53, 30–75, 30–84 and 30–100 %), differential scanning calorimetry and microstructure were determined after conditioning film specimens at 25 °C and 30…