Search results for "Proteins"

showing 10 items of 10069 documents

Studies on the insecticidal mechanism of Bacillus thuringiensis Vip3A and Cry proteins

2022

El control de plagas y patógenos ha tenido un efecto importante en la mejora del rendimiento de los sistemas agrícolas a nivel mundial. Diferentes tipos de insecticidas químicos se han usado extensivamente durante mucho tiempo para el control de plagas de insectos. Debido a la aparición de resistencias, problemas de contaminación de aguas y problemas de salud humana causados por dichos insecticidas de síntesis, la agricultura moderna necesita una estrategia de gestión integrada de plagas más saludable, respetuosa con el medio ambiente y sostenible. El uso de Bacillus thuringiensis (Bt) y sus proteínas insecticidas para el control de plagas es una de las estrategias biotecnológicas más impor…

pest managementinsecticidal proteinsvip3 proteinsUNESCO::CIENCIAS DE LA VIDAbacillus thuringiensisBt:CIENCIAS DE LA VIDA [UNESCO]
researchProduct

Isolation of Four Lytic Phages Infecting Klebsiella pneumoniae K22 Clinical Isolates from Spain

2020

This article belongs to the Special Issue Bacteriophage—Molecular Studies.

phage therapyPhage therapyPhage therapyKlebsiella pneumoniae<i>Klebsiella pneumoniae</i>medicine.medical_treatmentGenome ViralArticleHost SpecificityCatalysisMicrobiologylcsh:ChemistryInorganic ChemistryBacteriophageViral Proteins03 medical and health sciencesPodoviridaeProtein DomainsbacteriophagemedicineHumansBacteriophagesTypingPhysical and Theoretical ChemistryBacteriophagelcsh:QH301-705.5Molecular BiologyPhylogenySpectroscopy030304 developmental biologyWhole genome sequencingInfectivityLikelihood Functions0303 health sciencesbiology030306 microbiologyOrganic ChemistryGeneral Medicinebiology.organism_classification3. Good healthComputer Science ApplicationsKlebsiella pneumoniaelcsh:Biology (General)lcsh:QD1-999Lytic cycleSpainInternational Journal of Molecular Sciences
researchProduct

Appropriateness of requests for human serum albumin at the University Hospital of Palermo, Italy: a prospective study

2015

Abstract OBJECTIVE: First, to assess the appropriateness of requests for albumin using current guidelines; second, to evaluate physicians' compliance with this protocol. DESIGN: Descriptive, prospective study. SETTING: 'Paolo Giaccone' University Hospital in Palermo (Italy). PARTICIPANTS: The six departments with the highest orders for albumin. INTERVENTION: An experimental, pharmacist-driven process for daily orders of albumin was activated over a period of 1 month. Pharmacy personnel handed out order forms on six different wards. Physicians were required to select one of a number of intended uses listed on the form. MAIN OUTCOME MEASURES: Data on albumin and serum protein levels; number o…

pharmacymedicine.medical_specialtySerum albuminPharmacistHospital DepartmentsPharmacyUnnecessary ProceduresSettore MED/42 - Igiene Generale E ApplicataHospitals UniversityInformed consentIntensive caremedicineHumansunder-use and over-useProspective Studiesappropriate healthcareMedical prescriptionProspective cohort studyIntensive care medicineprofessionSerum Albuminbiologybusiness.industryHealth PolicyPublic Health Environmental and Occupational HealthGeneral MedicineBlood ProteinsHuman serum albuminItalyEmergency medicinebiology.proteinappropriateneGuideline Adherencebusinessmedicine.drug
researchProduct

Degradation of an alkaloid pheromone from the pale-brown chafer, Phyllopertha diversa (Coleoptera: Scarabaeidae), by an insect olfactory cytochrome P…

1999

AbstractThe pale-brown chafer, Phyllopertha diversa, utilizes an unusual alkaloid, 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione, as its sex pheromone. This compound is rapidly degraded in vitro by the antennal protein extracts from this scarab beetle. Demethylation at the N-1 position and hydroxylation of the aromatic ring have been identified as the major catabolic pathways. The enzyme responsible for the pheromone degradation is membrane-bound, requires NAD(P)H for activity and is sensitive to cytochrome P450 inhibitors, such as proadifen and metyrapone. The ability to metabolize this unusual pheromone was not detected in 12 species tested, indicating that the P450 system, specific to male P…

pheromone-degrading enzymemedia_common.quotation_subjectBiophysicsInsectOlfactionscarab beetleBiochemistryMass SpectrometryHydroxylationchemistry.chemical_compoundAlkaloidsCytochrome P-450 Enzyme SystemStructural BiologyMicrosomesBotanyGeneticsAnimalsCytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsSex AttractantsMolecular BiologyChromatography High Pressure LiquidDemethylationmedia_commonbiologyMolecular StructureProadifenCytochrome P450Cell BiologyMetyraponeProadifenColeopteraBiochemistrychemistrySex pheromonebiology.proteinQuinazolinesPheromoneInsect ProteinsChromatography Thin Layerpheromone inactivationolfactionFEBS letters
researchProduct

Observe while it happens : catching photoactive proteins in the act with non-adiabatic molecular dynamics simulations

2020

Organisms use photo-receptors to react to light. The first step is usually the absorption of a photon by a prosthetic group embedded inside the photo-receptor, often a conjugated chromophore. The electronic changes in the chromophore induced by photo-absorption can trigger a cascade of structural or chemical transformations that culminate into a response to light. Understanding how these proteins have evolved to mediate their activation process has remained challenging because the required time and spacial resolutions are notoriously difficult to achieve experimentally. Therefore, mechanistic insights into photoreceptor activation have been predominantly obtained with computer simulations. …

photoactive proteinsmolecular biologysense organsproteiinitmolekyylibiologia
researchProduct

Protein c-phycocyanin, structure, physicochemical and biological properties, methods of extraction

2022

С-phycocyanin (phycocyanin) is a pigment-protein complex of the lightharvesting phycobiliprotein family that takes part in the primary phase of photosynthesis in lower plants. The phycocyanin content depends on such factors as the species of microalgae, physical state of biomass, extraction techniques, etc. The main methods for obtaining phycocyanin from biomass include chemical, physical and enzyme treatments with the following purification by such methods as precipitation with ammonium sulfate, ion exchange chromatography, and gel filtration chromatography. The commercial value of phycocyanin is directly related to the methods of its obtaining, purification and purity. The ratio of absorb…

phycobiliproteinspurityc-phycocyaninGeneral Biochemistry Genetics and Molecular BiologyBiopolymers and Cell
researchProduct

Heat shock protein 70 and exercise: morphofunctional relationships

2008

physical exercise heat shock proteins muscle damage stress proteinsSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' Motorie
researchProduct

Function of odorant-binding proteins in the Drosophila melanogaster chemoreception

2017

National audience; Function of odorant-binding proteins in the Drosophila [i]melanogaster[/i] chemoreception. 18. rencontre du Club de neurobiologie des invertébrés

pichia pastorisanimal structures[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritioneducationodorant-binding proteinsdrosophila melanogasterhumanitiestestingCAFÉ assay[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionprotéineessaiprotein[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionhuman activitiespsychological phenomena and processeshealth care economics and organizationsfluorescent binding assays
researchProduct

Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis.

2003

Inflammation underlies both onset and perpetuation of atherosclerosis. Plasma lipoproteins transport the platelet-activating factor-acetylhydrolase (PAF-AH) with potentially anti-inflammatory activities. Our aim was to determine whether PAF-AH activity was associated with inflammatory markers and with coronary artery disease (CAD). PAF-AH activity and a panel of inflammatory mediators were measured in plasma of 496 patients with CAD and in 477 controls; 276 patients presented with stable angina pectoris and 220 with acute coronary syndrome (ACS). Individuals within the highest quartile of PAF-AH activity had an 1.8-fold increase in CAD risk [95% confidence interval (CI), 1.01 to 3.2; P = 0.…

platelet-activating factorAdultMaleRiskmedicine.medical_specialtyAcute coronary syndromePAF acetylhydrolaseStatinCross-sectional studymedicine.drug_classMutation MissenseInflammationAngiotensin-Converting Enzyme InhibitorsQD415-436Coronary Artery DiseaseBiochemistryCoronary artery diseaseEndocrinologySex FactorsRisk FactorsInternal medicinemedicineHumansAgedInflammationbusiness.industryCell BiologySyndromeMiddle Agedmedicine.diseaseConfidence intervalCross-Sectional StudiesQuartile1-Alkyl-2-acetylglycerophosphocholine EsteraseAcute DiseaseCardiologylipids (amino acids peptides and proteins)Femaleatherosclerosismedicine.symptombusinessJournal of lipid research
researchProduct

Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription fa…

2017

Background: Ectomycorrhizal (ECM) fungi develop a mutualistic symbiotic interaction with the roots of their host plants. During this process, they undergo a series of developmental transitions from the running hyphae in the rhizosphere to the coenocytic hyphae forming finger-like structures within the root apoplastic space. These transitions, which involve profound, symbiosis-associated metabolic changes, also entail a substantial transcriptome reprogramming with coordinated waves of differentially expressed genes. To date, little is known about the key transcriptional regulators driving these changes, and the aim of the present study was to delineate and functionally characterize the trans…

polypeptidelcsh:QH426-470Transcription factors; symbiosis; secreted proteins; transcriptional activator trap assay; yeast; transcriptome; ectomycorrhiza developmentlcsh:BiotechnologyTranscription Factors/geneticslaccaria bicolorpopulusyeastectomycorrhizasecreted proteinsLaccariadéveloppement biologiquelcsh:TP248.13-248.65MycorrhizaeTranscription factorsgenomicsGene Regulatory Networkstranscriptional activator trap assayLaccaria/geneticsectomycorrhiza developmentGene Expression ProfilingMycorrhizae/geneticsfungiMicrobiology and Parasitologypseudotsuga menziesiisymbiosisMicrobiologie et Parasitologielcsh:Genetics[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyontogenyectomycorhizeTranscription factors;ectomycorrhiza development;secreted proteins;symbiosis;transcriptional activator trap assay;transcriptome;yeastsymbiosetranscriptomefacteur de transcriptionResearch Article
researchProduct