Search results for "Proton"

showing 10 items of 5886 documents

Polysubstituted ferrocenes as tunable redox mediators

2018

A series of four ferrocenyl ester compounds, 1-methoxycarbonyl- (1), 1,1’-bis(methoxycarbonyl)- (2), 1,1’,3-tris(methoxycarbonyl)- (3) and 1,1’,3,3’-tetrakis(methoxycarbonyl)ferrocene (4), has been studied with respect to their potential use as redox mediators. The impact of the number and position of ester groups present in 1–4 on the electrochemical potential E1/2 is correlated with the sum of Hammett constants. The 1/1+–4/4+ redox couples are chemically stable under the conditions of electrolysis as demonstrated by IR and UV–vis spectroelectrochemical methods. The energies of the C=O stretching vibrations of the ester moieties and the energies of the UV–vis absorptions of 1–4 and 1+–4+ c…

redox mediator010402 general chemistryElectrosynthesis01 natural sciencesMedicinal chemistryRedoxFull Research Paperlcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryRedox titrationparamagnetic NMR spectroscopylcsh:ScienceElectrochemical potential010405 organic chemistryChemistryChemical shiftOrganic Chemistryferrocenespectroelectrochemistrycyclic voltammetry0104 chemical sciencesChemistryFerroceneProton NMRlcsh:QCyclic voltammetryBeilstein Journal of Organic Chemistry
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Jet fragmentation transverse momentum distributions in pp and p-Pb collisions at √s, √sNN = 5.02 TeV

2021

Jet fragmentation transverse momentum (jT) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at √sNN = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The jT values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured jT distributions are compared with a variety of parton-shower models. Herwig and Pythia 8 based models describe the data well for the higher jT region, while they underestimate the low…

related to the perturbative component of the fragmentation processthe measured trends are successfully described by all models except for Herwig. For the wide componentHerwig and PYTHIA 8 based models slightly underestimate the data for the higher jet transverse momentum region. These measurements set constraints on models of jet fragmentation and hadronisation.Nuclear and High Energy Physicswhile that of the inverse gamma function increases with increasing jet transverse momentum. For the narrow componentHeavy Ion Experimentsand with a Gaussian for lower jT values (called the “narrow component”)hiukkasfysiikkawhile they underestimate the lower jT region. The jT distributions are further characterised by fitting them with a function composed of an inverse gamma function for higher jT values (called the “wide component”)predominantly connected to the hadronisation process. The width of the Gaussian has only a weak dependence on jet transverse momentumJet fragmentation transverse momentum (jT) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at √sNN = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The jT values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured jT distributions are compared with a variety of parton-shower models. Herwig and PYTHIA 8 based models describe the data well for the higher jT region
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Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors

2016

Novel rhodesain inhibitors were developed by combining an enantiomerically pure 3-bromoisoxazoline warhead with a 1,4-benzodiazepine scaffold as specific recognition moiety. All compounds were proven to inhibit rhodesain with Ki values in the low-micromolar range. Their activity towards rhodesain was found to be coupled to an in vitro antitrypanosomal activity, with IC50 values ranging from the mid-micromolar to a low-micromolar value for the most active rhodesain inhibitor (R,S,S)-3. All compounds showed a good selectivity against the target enzyme since all of them were proven to be poor inhibitors of human cathepsin L. Novel rhodesain inhibitors were developed by combining an enantiomeri…

rhodesainPharmacologychemistry.chemical_classificationCathepsinPeptidomimetic010405 organic chemistryChemistryPeptidomimeticProton Magnetic Resonance SpectroscopyenPeptidomimetics; rhodesain; trypanosomaGeneral Medicine01 natural sciencesCombinatorial chemistryIn vitro0104 chemical sciencesCysteine Endopeptidases010404 medicinal & biomolecular chemistryEnzymeDrug DiscoveryIc50 valuesMoietyPeptidomimeticsCarbon-13 Magnetic Resonance SpectroscopytrypanosomaBiological evaluationJournal of Enzyme Inhibition and Medicinal Chemistry
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Positron production using a 9 MeV electron linac for the GBAR experiment

2020

For the GBAR (Gravitational Behaviour of Antihydrogen at Rest) experiment at CERN's Antiproton Decelerator (AD) facility we have constructed a source of slow positrons, which uses a low-energy electron linear accelerator (linac). The driver linac produces electrons of 9 MeV kinetic energy that create positrons from bremsstrahlung-induced pair production. Staying below 10 MeV ensures no persistent radioactive activation in the target zone and that the radiation level outside the biological shield is safe for public access. An annealed tungsten-mesh assembly placed directly behind the target acts as a positron moderator. The system produces $5\times10^7$ slow positrons per second, a performan…

safetyAntimatterNuclear and High Energy PhysicsCERN LabPhysics - Instrumentation and DetectorstungstenPositronAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesElectron01 natural sciences7. Clean energyLinear particle acceleratorpositron: particle source010305 fluids & plasmaselectron: pair productionNuclear physicselectron: linear acceleratorPositronPositron; Linear accelerator; Antimatter; Antihydrogen; Gravitation0103 physical sciences[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Detectors and Experimental TechniquesNuclear Experiment010306 general physicsAntihydrogenphysics.ins-detInstrumentationenergy: lowantihydrogenPhysicsLarge Hadron Collidergravitation 2Instrumentation and Detectors (physics.ins-det)linear acceleratorAntiproton DeceleratorPair productionradioactivityAntimattergravitation: accelerationPhysics::Accelerator PhysicsHigh Energy Physics::Experimentperformancepositron: yieldGravitationNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
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Frozen or dynamic? : An atomistic simulation perspective on the timescales of electrochemical reactions

2023

Electrochemical systems span a wide range of timescales, and several recent works have put forth the idea that the reaction environment should remain frozen and out of equilibrium during electrochemical electron or proton transfer reactions. Furthermore, simplified treatments of the electrochemical interface model the solvent and ions as frozen molecules. However, the claims and practices of a frozen environment strongly clash with most theoretical and simulation approaches developed to study electrochemical reaction rates. It has also been suggested that the electrode potential should not be fixed when simulating reaction rates due to conductivity limitations, which indicates constant pote…

samplingproton-coupled electron transferelektrokatalyysiGeneral Chemical EngineeringElectrochemistryelectrocatalysissimulointielektrolyytitelectrolytesolvent reorganizationlaskennallinen kemiasähkökemia
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Charged jet cross sections and properties in proton-proton collisions at $\sqrt{s}=7$ TeV

2015

The differential charged jet cross sections, jet fragmentation distributions, and jet shapes are measured in minimum bias proton-proton collisions at centre-of-mass energy $\sqrt{s}=7$ TeV using the ALICE detector at the LHC. Jets are reconstructed from charged particle momenta in the mid-rapidity region using the sequential recombination $k_{\rm T}$ and anti-$k_{\rm T}$ as well as the SISCone jet finding algorithms with several resolution parameters in the range $R=0.2$ to $0.6$. Differential jet production cross sections measured with the three jet finders are in agreement in the transverse momentum ($p_{\rm T}$) interval $20<p_{\rm T}^{\rm jet,ch}<100$ GeV/$c$. They are also consistent w…

shapes:Kjerne- og elementærpartikkelfysikk: 431 [VDP]parton distributionsMonte Carlo methodP(P)OVER-BAR COLLISIONSALICE Charged jet proton-proton 7 TeVATLAS DETECTOR01 natural sciencesSpectral lineHigh Energy Physics - Experimentdifferential charged jet cross sectionENERGYHigh Energy Physics - Experiment (hep-ex)ALICEFragmentation (mass spectrometry)Nuclear and High Energy Physics differential charged jet cross sectionfragmentation[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear Experiment (nucl-ex)ROOT-S(NN)=2.76 TEVNuclear ExperimentNuclear Experimentroot-s(nn)=2.76 tevatlas detectorPhysicsLarge Hadron Collidercross sectionPhysicsDetectorCharged particle3. Good health:Mathematics and natural scienses: 400::Physics: 430::Nuclear and elementary particle physics: 431 [VDP]charged jetsPRIRODNE ZNANOSTI. Fizika.:Nuclear and elementary particle physics: 431 [VDP]SHAPESTransverse momentumHADRON-COLLISIONSFRAGMENTATIONpp collisionsenergyParticle physicsNuclear and High Energy PhysicsAstrophysics::High Energy Astrophysical PhenomenaCharged jetVDP::Matematikk og naturvitenskap: 400::Fysikk: 430::Kjerne- og elementærpartikkelfysikk: 431FOS: Physical sciences[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]114 Physical sciencestransverse-momentumNuclear physicsMinimum bias(P)OVER-BAR-P COLLISIONS P(P)OVER-BAR COLLISIONS PP COLLISIONS PARTON DISTRIBUTIONS TRANSVERSE-MOMENTUM SHAPES ALGORITHM ENERGY0103 physical sciences7 TeVNuclear Physics - Experimentproton-protonALGORITHM010306 general physics(p)over-bar-p collisionsPP COLLISIONSta114(P)OVER-BAR-P COLLISIONSVDP::Mathematics and natural scienses: 400::Physics: 430::Nuclear and elementary particle physics: 431010308 nuclear & particles physics:Matematikk og naturvitenskap: 400::Fysikk: 430::Kjerne- og elementærpartikkelfysikk: 431 [VDP]TRANSVERSE-MOMENTUMNATURAL SCIENCES. Physics.(p)over-bar-p collisions ; parton distributions ; transverse-momentum ; root-s(nn)=2.76 tev ; hadron-collisions ; atlas detector ; pp collisions ; fragmentation ; shapes ; energy ; charged jet ; cross section ; proton-proton ; 7 TeVhadron-collisionsPARTON DISTRIBUTIONSALICE; Charged jet; proton-proton; 7 TeVproton-proton collisionsHigh Energy Physics::Experimentcharged jet
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Synthesis and characterization of Zwitterionic Zn(II) and Cu(II) coordination compounds with ring-substituted 2,2′-biimidazole derivatives

2016

Zwitterionic coordination compounds with strongly asymmetrical charge distribution were synthesized and characterized. Ring-substituted biimidazoles were used as the primary ligands for Zn and Cu compounds. Formation of Zwitterionic coordination compound was found to be strongly dependent on the pH of the reaction medium as well as on the ring and nitrogen substituents of the ligand. Reaction of the Df-R2biim (Df-R2biim = 2,2′-bi-1R-imidazole-5,5′-dicarboxaldehyde, R = Me, Et or Pr) with ZnCl2 in neutral conditions led to binuclear compounds [Zn2Cl4(Df-R2biim)2] with two bridging ligands (1a–c). Reaction with CuCl2·2H2O gave neutral mononuclear compound [CuCl2(Df-Me2biim)] (1d) with chelati…

sinkki (metallit)DenticityStereochemistrykupariProtonation010402 general chemistry01 natural sciencesMedicinal chemistryAldehydeCoordination complexInorganic Chemistrycrystal structureschemistry.chemical_compoundbiimidazoleMaterials ChemistryImidazoleChelationPhysical and Theoretical Chemistryta116chemistry.chemical_classificationzwitterionic compunds010405 organic chemistryLigandzincAcetal0104 chemical scienceschemistrycoppernon-coordinated compoundsInorganica Chimica Acta
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Functional molecular materials: supramolecular networks and coordination polymers with optical and/or magnetic properties

2020

El camp dels materials moleculars atrau l’atenció de molts científics degut al gran potencial de la química molecular en el disseny de materials amb un ajust precís de les seues propietats. Els dos projectes tractats en aquesta tesi representen dos temes que destaquen en aquesta àrea, materials de transició d’espín i polímers de coordinació amb propietats òptiques i/o magnètiques, gràcies al seu significant progrés i ràpid desenvolupament en els últims anys. La primera part d’aquesta tesi es basa en l’ús d’enllaços d’hidrogen en el disseny de xarxes multifuncionals de ferro(II) amb transicions d’espín abruptes. El capítol 1 és una introducció a aquest tema des de la perspectiva dels complex…

sonogashira reactionpicolinatespin crossoverUNESCO::QUÍMICAhydrogen bondsferroelectricsiron(II) complexesproton migrationisomerisationsensing experiments:QUÍMICA [UNESCO]
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Study of eta and eta' Photoproduction at MAMI

2017

The reactions γp→ηp and γp→η′p are measured from their thresholds up to the center-of-mass energy W=1.96 GeV with the tagged-photon facilities at the Mainz Microtron, MAMI. Differential cross sections are obtained with unprecedented statistical accuracy, providing fine energy binning and full production-angle coverage. A strong cusp is observed in the total cross section for η photoproduction at the energies in the vicinity of the η′ threshold, W=1896 MeV (Eγ=1447 MeV). Within the framework of a revised ηMAID isobar model, the cusp, in connection with a steep rise of the η′ total cross section from its threshold, can only be explained by a strong coupling of the poorly known N(1895)1/2− sta…

spectrometer ; photons ; proton ; taps
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Thermodynamic and spectroscopic study of the binding of dimethyltin(IV) by citrate at 25°C

2006

Thermodynamic (potentiometric and calorimetric) and spectroscopic ( 1 H NMR, 119 Sn Mossbauer) studies were performed in aqueous solution in order to characterize the interaction of dimethyltin(IV) cation with citrate ligand. Six species {(CH 3 ) 2 Sn(cit) - ; [(CH 3 ) 2 Sn] 2 (cit) 2 2- ; (CH 3 ) 2 Sn(cit)H 0 ; (CH 3 ) 2 Sn(cit)OH 2- ; [(CH 3 ) 2 Sn] 2 (cit)OH 0 ; [(CH 3 ) 2 Sn] 2 (cit)(OH) 2 - } were found. All the species formed in this system are quite stable and formation percentages are fairly high. For example, at pH = 7.5 and C (CH3)2Sn = C cit = 10 mmol l -1 , E% for [(CH 3 ) 2 Sn] 2 (cit)(OH) 2 - and (CH 3 ) 2 Sn(cit)OH 2- species reaches 65%. Overall thermodynamic parameters obta…

spectroscopyAqueous solutionthermodynamic propertiesdimethyltin(IV) complexesChemistryLigandStereochemistryPotentiometric titrationthermodynamic propertiethermodynamic properties; calorimetry; spectroscopy; potentiometry; dimethyltin(IV) complexesGeneral ChemistryTricarboxylateInorganic ChemistryMetalOctahedronpotentiometryvisual_artMössbauer spectroscopyvisual_art.visual_art_mediumProton NMRPhysical chemistrySettore CHIM/01 - Chimica Analiticacalorimetry
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