Search results for "Protonation"

showing 10 items of 583 documents

Cu2+and AMP complexation of enlarged tripodal polyamines

2006

The synthesis, characterization, Cu2+ coordination and interaction with AMP of three tripodal polyamines are reported. The polyamines are based on the structure of the tetraamine (tren) which has been enlarged with three propylamino functionalities (TAL), with a further anthrylmethyl fragment at one of its terminal primary nitrogens (ATAL) or with naphthylmethyl fragments at its three ends (N3TAL). The protonation constants of all three polyamines show that at pH 6, all six primary and secondary nitrogen atoms in the arms are protonated. The interaction with Cu2+ and AMP (adenosine-5′-monophosphate) has been studied by potentiometric, UV-Vis, ESI-MS spectroscopy and NMR techniques. pH-Metri…

Binding SitesAqueous solutionMolecular StructureStereochemistryChemistrySpectrum AnalysisPotentiometric titrationProtonationAdenosine MonophosphateAdductInorganic ChemistryParamagnetismPolyaminesPotentiometrySpectroscopyTernary operationCopperStoichiometryDalton Trans.
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Diorganotin(IV) N-acetyl-L-cysteinate complexes: synthesis, solid state, solution phase, DFT and biological investigations.

2009

Diorganotin(IV) complexes of N-acetyl-L-cysteine (H(2)NAC; (R)-2-acetamido-3-sulfanylpropanoic acid) have been synthesized and their solid and solution-phase structural configurations investigated by FTIR, Mössbauer, (1)H, (13)C and (119)Sn NMR spectroscopy. FTIR results suggested that in R(2)Sn(IV)NAC (R = Me, Bu, Ph) complexes NAC(2-) behaves as dianionic tridentate ligand coordinating the tin(IV) atom, through ester-type carboxylate, acetate carbonyl oxygen atom and the deprotonated thiolate group. From (119)Sn Mössbauer spectroscopy it could be inferred that the tin atom is pentacoordinated, with equatorial R(2)Sn(IV) trigonal bipyramidal configuration. In DMSO-d(6) solution, NMR spectr…

Binding SitesMolecular StructureLigandStereochemistryCell SurvivalSpectrum Analysischemistry.chemical_elementAntineoplastic AgentsNuclear magnetic resonance spectroscopyBiochemistryMedicinal chemistryAcetylcysteineCell LineInorganic Chemistrychemistry.chemical_compoundTrigonal bipyramidal molecular geometryDeprotonationchemistryMössbauer spectroscopyOrganotin CompoundsOrganotin(IV) FTIR Mössbauer NMR DFT Antitumor activityHumansDensity functional theoryCarboxylateTinJournal of inorganic biochemistry
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Colorimetric sensing of anions by a neutral biphenyl based amide receptor

2006

A new colorimetric sensor for fluoride is described. Compound 1 shows an open structure and its behaviour is compared with that of two related closed compounds 2 and 3. In all cases, the red colour developed in the presence of fluoride can be related to deprotonation processes, however ligand 1 gives rise to a faster colour change than 2 or 3 because of its higher flexibility. Other halides as well as carboxylates have been studied and the stoichiometry and complexation constants for the corresponding ligands have been determined.

BiphenylChemistryLigandOrganic ChemistryInorganic chemistryHalidePhotochemistrylcsh:QD241-441chemistry.chemical_compoundDeprotonationlcsh:Organic chemistryAmideReceptorFluorideStoichiometryArkivoc
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Biphenyl macrolactams in anion complexation. Selective naked-eye fluoride recognition

2004

Two colorimetric anion sensors 1 and 2 allow for the selective differentiation of fluoride in the presence of other anions. Two different types of species have been observed in the complexation process, one of them is a co-ordination complex and the other is a salt generated by ligand deprotonation. The deprotonation reaction induces a conformational change, giving rise to a symmetrical species. This species is responsible for colour development. Ligand 3 has a similar structure and does not give rise to any colour modification due to presence of the dimethylamino groups in the biphenyl moiety. The X-ray structure of ligand 2 is also reported and compared with that of ligand 1, that had bee…

Biphenylchemistry.chemical_classificationConformational changeStereochemistryLigandOrganic ChemistrySalt (chemistry)BiochemistryMedicinal chemistrychemistry.chemical_compoundDeprotonationchemistryDrug DiscoveryMoietyNaked eyeFluorideTetrahedron
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A polyazacyclophane containing two biphenyl subunits as a versatile cation and anion receptor

2002

Abstract The synthesis, protonation behaviour and coordination capabilities towards Cu 2+ , Zn 2+ and towards the nucleotides ATP and ADP of a cyclophane ditopic receptor 2,6,10,23,27,31-hexaaza[11,11](2,2′)biphenylophane containing two 2,2′-biphenylene spacers linked to the ends of 1,5,9-triazanonane chains are presented.

Biphenylchemistry.chemical_classificationStereochemistryOrganic ChemistryProtonationGeneral ChemistryInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryNucleotideReceptorAnion receptorCyclophaneJournal of Supramolecular Chemistry
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Polyazapodands Derived from Biphenyl. Study of their Behaviour as Conformationally Regulated Fluorescent Sensors

2004

Eight new polyazapodands containing a 4,4′-substituted biphenyl moiety have been synthesised. Four (7, 8, 9 and 11) are functionalised on positions 4 and 4′ with a nitro group and four (1, 2, 3 and 10) with a dimethylamino substituent. Comparison of the emission behaviour of 1, 2, 3 with that of the reference compounds 10 and tetramthylbenzidine, clearly suggests that a modification in the dihedral angle between the biphenyl rings is an important factor in determining the fluorescent response of the molecule. The fluorescence is pH dependent, due to the formation of intramolecular hydrogen bonds between protonated aliphatic nitrogens and a carbonyl oxygen, which influences the aforementione…

Biphenylchemistry.chemical_compoundCrystallographyChemistryStereochemistryHydrogen bondIntramolecular forceSubstituentMoietyMoleculeProtonationGeneral ChemistryDihedral angleSupramolecular Chemistry
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ChemInform Abstract: Experimental and Theoretical Studies on the Electronic Spectra of Indole-3-acetic Acid and Its Anionic and Protonated Species.

2010

Abstract The geometrical and electronic structure of indole-3-acetic acid (IAH) have been investigated using the MINDO/3 molecular orbital method, the geometries being optimized by Rinaldi's method. The UV spectrum of IAH has been recorded in different solvents. The corresponding spectra of IAH + 2 and IA − were also respectively obtained, from IAH in different H 2 SO 4 /water mixtures and NaOH solutions. The agreement of experimental spectra with the ones theoretically calculated by the CNDO/M-Cl method after optimization of the κ parameter, is discussed. The p K a values of IAH have also been determined from the IAH + 2 spectra and are compared with literature data.

CNDO/2chemistry.chemical_compoundchemistryPhysical chemistryA valueProtonationMolecular orbitalGeneral MedicineElectronic structureIndole-3-acetic acidMINDOSpectral lineChemInform
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Reversible switching of the electronic ground state in a pentacoordinated Cu(ii) complex.

2013

International audience; An easy reversible switching of the electronic ground state in a pentacoordinated copper(ii) complex is reported for the first time. The simple protonation of a carboxylic group in a Cu(ii) complex with a {dx(2)-y(2)}(1) electronic configuration leads to a flip of the ground electronic configuration from {dx(2)-y(2)}(1) to {dz(2)}(1) in the metal ion.

Carboxylic groupMolecular Conformationchemistry.chemical_elementInorganic compoundsElectronsProtonationCrystallography X-Ray010402 general chemistry01 natural sciencesCatalysisMetalCoordination ComplexesComputational chemistryElectronic ground stateMaterials Chemistry010405 organic chemistryChemistryMetals and AlloysGeneral Chemistry[CHIM.MATE]Chemical Sciences/Material chemistryCopper3. Good health0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsReversible switchingvisual_artCeramics and Compositesvisual_art.visual_art_mediumQuantum TheoryPhysical chemistryElectron configurationGround stateCopper
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A Rational Design for Imidazolate-Bridged Linear Trinuclear Compounds from Mononuclear Copper(II) Complexes with 2-[((Imidazol-2-ylmethylidene)amino)…

2001

Two mononuclear copper(II) complexes with the unsymmetrical tridentate ligand 2-[((imidazol-2-ylmethylidene)amino)ethyl]pyridine (HL), [Cu(HL)(H2O)](ClO4)2.2H2O (1) and [Cu(HL)Cl2] (2), have been prepared and characterized. The X-ray analysis of 2 revealed that the copper(II) ion assumes a pentacoordinated square pyramidal geometry with an N3Cl2 donor set. When 1 and 2 are treated with an equimolecular amount of potassium hydroxide, the deprotonation of the imidazole moiety promotes a self-assembled process, by coordination of the imidazolate nitrogen atom to a Cu(II) center of an adjacent unit, leading to the polynuclear complexes [[Cu(L)(H2O)](ClO4)]n (3) and [[Cu(L)Cl].2H2O]n (4). Variab…

Chemical PhenomenaPyridinesStereochemistryMolecular Conformationchemistry.chemical_elementCrystallography X-RayLigandsInorganic ChemistryMagneticschemistry.chemical_compoundDeprotonationImidazolatePyridineOrganometallic CompoundsImidazolePhysical and Theoretical ChemistryIsostructuralChemistry PhysicalChemistryLigandImidazolesHydrogen BondingCopperSquare pyramidal molecular geometryCrystallographyCopperInorganic Chemistry
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The Reduction Pathway of End-on Coordinated Dinitrogen. I. Vibrational Spectra of Mo/W−N2, −NNH, and −NNH2 Complexes and Quantum Chemistry Assisted N…

1999

Infrared and Raman spectra of [M(N(2))(2)(dppe)(2)] (M = W, Mo) and the two protonated derivatives [WF(NNH)(dppe)(2)] and [WF(NNH(2))(dppe)(2)](+) (dppe = 1,2-bis(diphenylphosphino)ethane) are presented. Using isotope substituted compounds ((15)N and D) the vibrations of the Y-M-N(2)H(x)() (x = 0, 1, 2; Y = N(2), F) central unit are identified, in particular the M-N and N-N stretching modes. In case of the monoprotonated systems, an equilibrium between metal- and nitrogen-protonated species exists that is clearly detectable in the IR spectra. Making use of theoretical force fields, a quantum chemistry assisted normal coordinate analysis (QCA-NCA) is performed for all three tungsten systems …

ChemistryBond strengthInfraredInfrared spectroscopyProtonationQuantum chemistryInorganic ChemistryMetalsymbols.namesakeCrystallographyTransition metalComputational chemistryvisual_artsymbolsvisual_art.visual_art_mediumPhysical and Theoretical ChemistryRaman spectroscopyInorganic Chemistry
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