Search results for "Pyridone"

showing 10 items of 46 documents

CCDC 839168: Experimental Crystal Structure Determination

2012

Related Article: B.Osmialowski, E.Kolehmainen, S.Ikonen, K.Ahonen, M.Lofman|2011|J.Mol.Struct.|1006|678|doi:10.1016/j.molstruc.2011.10.034

Space GroupCrystallography2-(Isobutanoylamino)-6(1H)-pyridoneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 839167: Experimental Crystal Structure Determination

2012

Related Article: B.Osmialowski, E.Kolehmainen, S.Ikonen, K.Ahonen, M.Lofman|2011|J.Mol.Struct.|1006|678|doi:10.1016/j.molstruc.2011.10.034

Space GroupCrystallographyCrystal System2-(Propanoylamino)-6(1H)-pyridoneCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 839169: Experimental Crystal Structure Determination

2012

Related Article: B.Osmialowski, E.Kolehmainen, S.Ikonen, K.Ahonen, M.Lofman|2011|J.Mol.Struct.|1006|678|doi:10.1016/j.molstruc.2011.10.034

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters2-(Adamantanylcarbonylamino)-6(1H)-pyridoneExperimental 3D Coordinates
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CCDC 117866: Experimental Crystal Structure Determination

1999

Related Article: S.Perrin, K.Monnier, B.Laude, M.Kubicki, O.Blacque|1999|Eur.J.Org.Chem.|1999|297|doi:10.1002/(SICI)1099-0690(199901)1999:13.0.CO;2-J

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterstrans-(Ethyl 36-diphenyl-3-p-tolylamino-34-dihydro-2-pyridone-4-carboxylate)Experimental 3D Coordinates
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Durability of Dolutegravir-Based Regimens: A 5-Year Prospective Observational Study

2021

This study evaluates the frequency and causes of dolutegravir (DTG) discontinuation along 5 years of follow-up, in both antiretroviral treatment (ART)-naive and experienced people living with HIV (PLWH). This is a prospective multi-center cohort study enrolling PLWH on DTG from July 2014 until November 2020. DTG-durability was investigated using the Kaplan-Meier survival curve. The Cox proportional-hazards model was used for estimating the hazard ratio (HR) of DTG discontinuation for any cause, and for adverse events (AEs). Nine hundred sixty-three PLWH were included, 25.3% were women and 28.0% were ART-naive. Discontinuations for any causes were 10.1 [95% confidence interval (95% CI) 8.9-1…

adverse events; dolutegravir; durability; HIV; safety; toxicity; virolgical failure; Cohort Studies; Female; Heterocyclic Compounds 3-Ring; Humans; Middle Aged; Oxazines; Piperazines; Prospective Studies; Pyridones; Anti-HIV Agents; HIV InfectionssafetyPediatricsmedicine.medical_specialtySettore MED/17 - Malattie InfettivePyridonesAnti-HIV AgentsOxazineHuman immunodeficiency virus (HIV)adverse eventHIV Infectionsvirolgical failurePyridonemedicine.disease_cause3-RingHIV Infections.PiperazinesCohort Studieschemistry.chemical_compoundHeterocyclic CompoundsHIV; adverse events; dolutegravir; durability; safety; toxicity; virolgical failureOxazinesAntiretroviral treatmentMedicineHumansProspective StudiesAdverse effectPiperazinebusiness.industryPublic Health Environmental and Occupational HealthHIVtoxicityAnti-HIV AgentMiddle Agedadverse eventsDiscontinuationdolutegravirvirolgical failure.Prospective StudieInfectious DiseaseschemistryDolutegravirdurabilityObservational studyFemaleCohort StudiebusinessHeterocyclic Compounds 3-RingHuman
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CCDC 725083: Experimental Crystal Structure Determination

2010

Related Article: G.Agusti, C.Bartual, V.Martinez, F.J.Munoz-Lara, A.B.Gaspar, M.C.Munoz, J.A.Real|2009|New J.Chem.|33|1262|doi:10.1039/b905674b

bis(26-bis(2-Pyridyl)-4(1H)-pyridone-NN'N'')-cobalt(ii) bis(trifluoromethanesulfonate) monohydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 725084: Experimental Crystal Structure Determination

2010

Related Article: G.Agusti, C.Bartual, V.Martinez, F.J.Munoz-Lara, A.B.Gaspar, M.C.Munoz, J.A.Real|2009|New J.Chem.|33|1262|doi:10.1039/b905674b

bis(26-bis(2-Pyridyl)-4(1H)-pyridone-NN'N'')-cobalt(ii) bis(trifluoromethanesulfonate) monohydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 725085: Experimental Crystal Structure Determination

2010

Related Article: G.Agusti, C.Bartual, V.Martinez, F.J.Munoz-Lara, A.B.Gaspar, M.C.Munoz, J.A.Real|2009|New J.Chem.|33|1262|doi:10.1039/b905674b

bis(26-bis(2-Pyridyl)-4(1H)-pyridone-NN'N'')-cobalt(ii) bis(trifluoromethanesulfonate) monohydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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ChemInform Abstract: Desymmetrization Reactions on 4-Pyridone Using Carbohydrate Templates.

2010

chemistry.chemical_compoundTemplatechemistryOrganic chemistryGeneral MedicineCarbohydrate4-PyridoneDesymmetrizationChemInform
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Synthesis, Characterization, and Cu(2+) Coordination Studies of a 3-Hydroxy-4-pyridinone Aza Scorpiand Derivative.

2016

The synthesis, acid-base behavior, and Cu(2+) coordination chemistry of a new ligand (L1) consisting of an azamacrocyclic core appended with a lateral chain containing a 3-hydroxy-2-methyl-4(1H)-pyridinone group have been studied by potentiometry, cyclic voltammetry, and NMR and UV-vis spectroscopy. UV-vis and NMR studies showed that phenolate group was protonated at the highest pH values [log K = 9.72(1)]. Potentiometric studies point out the formation of Cu(2+) complexes of 1:2, 2:2, 4:3, 1:1, and 2:1 Cu(2+)/L1 stoichiometries. UV-vis analysis and electrochemical studies evidence the implication of the pyridinone moieties in the metal coordination of the 1:2 Cu(2+)/L1 complexes. L1 shows …

inorganic chemicalsMagnetic Resonance SpectroscopyStereochemistryPyridinesPyridonesPotentiometric titrationProtonationChemistry Techniques Synthetic010402 general chemistry010403 inorganic & nuclear chemistryElectrochemistryCrystallography X-Ray01 natural sciencesMedicinal chemistryAntioxidantsCoordination complexInorganic Chemistrychemistry.chemical_compoundStructure-Activity RelationshipCoordination ComplexesHumansChelationPhysical and Theoretical ChemistryCell ProliferationChelating Agentschemistry.chemical_classificationLigandHydrogen-Ion Concentration0104 chemical scienceschemistryPotentiometrySpectrophotometry UltravioletCyclic voltammetryDerivative (chemistry)CopperHeLa CellsInorganic chemistry
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