Search results for "Q2"

showing 10 items of 98 documents

12q21 Interstitial Deletions: Seven New Syndromic Cases Detected by Array-CGH and Review of the Literature.

2022

Interstitial deletions of the long arm of chromosome 12 are rare, with a dozen patients carrying a deletion in 12q21 being reported. Recently a critical region (CR) has been delimited and could be responsible for the more commonly described clinical features, such as developmental delay/intellectual disability, congenital genitourinary and brain malformations. Other, less frequent, clinical signs do not seem to be correlated to the proposed CR. We present seven new patients harboring non-recurrent deletions ranging from 1 to 18.5 Mb differentially scattered across 12q21. Alongside more common clinical signs, some patients have rarer features such as heart defects, hearing loss, hypotonia an…

dysmorphismsComparative Genomic Hybridization12q21 deletiongenetic counselingcopy number variants (CNVs)DNA Copy Number Variationscongenital anomaliesarray-CGH; 12q21 deletion; copy number variants (CNVs); variation intolerant genes; loss of function; developmental delay/intellectual disability (DD/ID); congenital anomalies; dysmorphisms; genetic counseling; patient management12q21 deletion array-CGH congenital anomalies copy number variants (CNVs) developmental delay/intellectual disability (DD/ID) dysmorphisms genetic counseling loss of function patient management variation intolerant genesdevelopmental delay/intellectual disability (DD/ID)variation intolerant genesloss of functionSettore MED/03 - Genetica MedicaChromosome Structuresarray-CGHIntellectual DisabilityGeneticsHumansChromosome Deletionpatient managementGenetics (clinical)Genes
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ANALYSIS OF HOWECOTOURISMIN PROTECTED AREAS INFLUENCE THE DEVELOPMENT OF LOCAL COMMUNITIES

2013

Tourism, which, by its specific, uses natural resources, is an important contribution to environmental damage. In this context, efforts to find and promote holiday forms that have a low environmentalimpact, forms known as ecotourism, ecological tourism, tourism in protected areas, green tourism. Tourism industry stakeholders have become increasingly sensitive to environmental issues and few are those who now believe commercial activities have nothing to do with the development of ecological actions. Also many tour operators believe that the natural resources have economic value only if they are reasonably valued.

ecotourism protected areas sustainable tourism development local community green tourismjel:Q26jel:Q56jel:Q27Review of General Management
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Self-enforcing international environmental agreements revisited

2004

In Barrett's (1994) paper on transboundary pollution abatement is shown that if the signatories of an international environmental agreement act in a Stackelberg fashion, then, depending on parameter values, a self-enforcing IEA can have any number of signatories between two and the grand coalition. Barrett obtains this result using numerical simulations and also ignoring the fact that emissions must be non-negative. Recent attempts to use analytical approaches and to explicitly recognize the non-negativity constraints have suggested that the number of signatories of a stable IEA may be very small. The way such papers have dealt with non-negativity constraints is to restrict parameter values…

international externalities self-enforcing environmental agreements Stackelberg equilibrium non-negative emissions constraintsEconomics and EconometricsPublic economicsjel:D62jel:C72Transboundary pollutionjel:F02Grand coalitionMicroeconomicsrestrictjel:Q20Key (cryptography)EconomicsStackelberg competitionOxford Economic Papers
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Identifying a supply-chain related to the use of renewable natural resource: Case studies from France and Aquitaine region

2015

This paper aims to build a method to identify an economic sector. This type of method attempts to identify a pool of sub sector showing a strong intensity of economic flows between them. In this study, we show the potential of input output models for this type of analysis. Two types of contributions have been done here. First we improve the sub sector selection. Then we improve the calculation of the « economic distance between sub sectors belonging to the same sector. These improvements are applied to identified the wood sector in France but also at the regional level of Aquitaine. The empirical results show the features of sectors can vary between France and regions, mainly because of reg…

jel:L23Input-output analysis wood sector regional economicsjel:C67jel:R1jel:Q23
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Sustainable Development and Technological Impact on CO 2 Reducing Conditions in Romania

2015

Climate change is a reality all over the world, and its complexity is increasing. Therefore, sustainability has become a national and international concern, ingrained in many organizational processes. The ability of organizations to respond to sustainability concerns is sometimes hindered by the complexity of integrating sustainability into business models and by the need to rethink their strategic directions. In Romania, sustainable development has become a priority for businesses, but even though companies are showing some concern, there are yet to demonstrate any full commitment (they are mainly concerned with areas such as society and the environment). This paper assesses Romania’s invo…

jel:O13jel:QCO 2 ; energy; GHG; sustainable development; transportjel:Q0jel:Q2jel:Q56jel:Q3jel:Q5Sustainability
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KLUM@GTAP: Introducing biophysical aspects of land-use decisions into a general equilibrium model: A coupling experiment

2006

In this paper the global agricultural land use model KLUM is coupled to an extended version of the computable general equilibrium model (CGE) GTAP in order to consistently assess the integrated impacts of climate change on global cropland allocation and its implication for economic development. The methodology is innovative as it introduces dynamic economic land-use decisions based also on the biophysical aspects of land into a state-of-the-art CGE; it further allows the projection of resulting changes in cropland patterns on a spatially more explicit level. A convergence test and illustrative future simulations underpin the robustness and potentials of the coupled system. Reference simulat…

jel:Q15jel:R14jel:C68jel:Q24Land-use change computable general equilibrium modeling integrated assessment climate changejel:Q17
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Panorámica de la problemática medioambiental en el mundo y en España

2008

As energy resources become scarce and pollution increases, fundamental and often irreversible changes are affecting our global ecosystem, and these changes are already having an influence on countries’ potential for economic growth and development. In this article we examine the principal environmental problems worldwide and how such problems are affected by inequality between countries. In Spain’s case, the basic problems are greenhouse gas emissions, problems relating to water management and issues concerning territory and biodiversity. We also call for the application of economic funding mechanisms to implement environmental policies.

jel:Q32jel:Q20jel:Q25jel:Q01Environmental problems inequality and the environment climate change water management biodiversity.CIRIEC-España, revista de economía pública, social y cooperativa
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The Correlation Between Human Capital and Gross Added Value in the Bioeconomy Sectors at the European Union (EU) Country Level

2019

Abstract The paper aims to prove the link between human capital and gross added value in bioeconomy sectors in the EU countries. Data from EUROSTAT data base regarding employment and gross added value in 6 bioeconomy sectors were used in a cross-country regression analysis. The econometric analysis of cross-country data shows a positive correlation between human capital in bioeconomy sectors and their gross output in 2015 in 26 European countries. It is found also that the correlation is stronger in the highly developed economies as in the central-eastern countries, as well as in the European economy.

m12Economics and EconometricsStrategy and Managementm10010501 environmental sciences01 natural sciencesHuman capitalq57Green economygreen economyRegional economics. Space in economicsCountry level0502 economics and businessAdded valueEconomicsmedia_common.cataloged_instanceBusiness and International ManagementEuropean uniondevelopmentHB71-740105 earth and related environmental sciencesmedia_commoncompetenciesq2005 social sciencesGross outputsmart economyEconometric analysisRegression analysisInternational economicsEconomics as a scienceHT388050203 business & managementFinanceStudia Universitatis „Vasile Goldis” Arad – Economics Series
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Consumers’ Sustainability Perceptions of the Supply Chain of Locally Produced Food

2010

This article is based on a qualitative focus group study regarding consumer perceptions about the sustainability of locally produced food supply chains. Sustainability perceptions were analyzed through thematic content analysis, where the most important economic, environmental and social themes of the supply chain were emphasized. According to the research findings, the socio-cultural aspects encompassing locally produced food form the most important sustainability dimension for consumers. Although the sample size is small, consisting of 19 consumers and limited to Central Finland, the findings suggest that the sustainability of local food should be promoted via socio-cultural arguments alo…

media_common.quotation_subjectSupply chainGeography Planning and DevelopmentTJ807-830Management Monitoring Policy and Lawlocally produced food; supply chain; sustainability; consumer perceptions; focus groupTD194-195Consumer educationRenewable energy sourcesPerceptionjel:QGE1-350Dimension (data warehouse)Marketinglocally produced foodsupply chainmedia_commonconsumer perceptionsEnvironmental effects of industries and plantsRenewable Energy Sustainability and the EnvironmentFood marketingjel:Q0jel:Q2jel:Q3sustainabilityFocus groupjel:Q5Environmental sciencesjel:O13Sustainabilityfocus groupBusinessThematic analysisjel:Q56Sustainability
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Prevalence estimation of celiac disease in the general adult population of Latvia using serology and HLA genotyping

2015

Background: Prevalence estimates for celiac disease (CD) depend on the method used. The role of deamidated gliadin peptide (DGP) and genetic testing in epidemiological studies and diagnostic settings of celiac disease (CD) has still to be established. Objectives: The objective of this article is to assess the prevalence of CD in Latvia by combining serological tests with DQ2.5/ DQ8 testing. Methods: A total of 1444 adults from a randomly selected cross-sectional general population sample were tested by ELISA for tTG IgA, DGP IgA and IgG antibodies (QUANTA Lite, Inova Diagnostics Inc). Samples with tTG IgA 20U were tested for EMA IgA by indirect immunofluorescence assay, and all specimens wi…

medicine.medical_specialty:MEDICINE [Research Subject Categories]Tissue transglutaminasePopulationSerologyChemiluminescent assaysEpidemiologyGenotypePrevalenceCeliac diseaseMedicineDQ2.5/8 genotypeeducationGenotypingGenetic testingeducation.field_of_studyDeamidated gliadin peptidemedicine.diagnostic_testbiologybusiness.industryTissue transglutaminaseGastroenterologynutritional and metabolic diseasesOriginal ArticlesOncologyImmunologybiology.proteinAntibodybusinessUnited European Gastroenterology Journal
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