Search results for "RACE"
showing 10 items of 4458 documents
Dietary exposure in utero and during lactation to a mixture of genistein and an anti-androgen fungicide in a rat mammary carcinogenesis model
2015
Endocrine disruptors may play substantial roles in the high incidence of breast cancer. We previously described how early exposure to the mixture of phytoestrogen genistein (G) and the anti-androgen vinclozolin (V) affects peripubertal mammary development. This study evaluates the carcinogenic potential of exposure to V alone or associated with G from conception until weaning in Wistar rats. Dams were exposed to V, G or GV during pregnancy/lactation. At PND50 offspring were treated with DMBA[7,12-dimethylbenz(a)anthracene]. V or GV maternal exposure decreased number of DMBA-induced mammary tumors in the offspring, without significant modifications in tumor incidence, multiplicity and latenc…
Effets à long terme de l'apport répété de déchets organiques sur l'évolution de la matière organique et des éléments trace métalliques dans un sol sa…
2002
The distribution of trace metal elements (ETM) in soils depends on physico-chemical characteristics of the soil (pH, redox potential …) and does not remain fixed during time. The objective of this work was to study the long-term effects of the organic waste applications (sewage sludge and manure) on the evolution of the ETM and the organic matter in a cultivated soil. This study was made on the acid sandy soil of the experimental site of Ambarès (Gironde) set up in 1974 by the INRA of Bordeaux. During 20 years, this soil, cultivated in maize, received various organic applications (manure 10 t ha-1 year-1, sludges 10 t ha-1 year-1 and sludges 100 t ha-1 year-1), which stopped in 1993. This s…
Stereoselective synthesis of o-bromo (or iodo)aryl P-chirogenic phosphines based on aryne chemistry.
2012
The efficient synthesis of chiral or achiral tertiary phosphines bearing an o-bromo (or iodo)aryl substituent is described. The key step of this synthesis is based on the reaction of a secondary phosphine borane with the 1,2-dibromo (or diiodo)arene, owing to the formation in situ of an aryne species in the presence of n-butyllithium. When P-chirogenic secondary phosphine boranes were used, the corresponding o-halogeno-arylphosphine boranes were obtained without racemization in moderate to good yields and with ee up to 99%. The stereochemistry of the reaction, with complete retention of the configuration at the P atom, has been established by X-ray structures of P-chirogenic o-halogenopheny…
Dynamics of copper and zinc sedimentation in a lagooning system receiving landfill leachate.
2013
9 pages; International audience; This study characterises the sediment dredged from a lagooning system composed of a settling pond and three lagoons that receive leachates from a municipal solid waste (MSW) landfill in France. Organic carbon, carbonate, iron oxyhydroxides, copper (Cu) and zinc (Zn) concentrations were measured in the sediment collected from upstream to downstream in the lagooning system. In order to complete our investigation of sedimentation mechanisms, leachates were sampled in both dry (spring) and wet (winter) seasonal conditions. Precipitation of calcite and amorphous Fe-oxyhydroxides and sedimentation of organic matter occurred in the settling pond. Since different di…
Introduction et dispersion d'une espèce envahissante : le cas de l'ambroisie à feuilles d'armoise (Ambrosia artemisiifolia L.) en France
2011
National audience; Ambrosia artemisiifolia L. (common ragweed) was accidentally introduced into France in the 1860s. Its single vector of introduction in Europe was red clover seeds (Trifolium pratense L.), probably coming from Pennsylvania, United States at the time. A. artemisiifolia was later introduced into France in many places and at different times. This species has no natural or effective seed dispersal mechanisms and the spread of this weed in the territory is ensured by human activities that carry the seeds and create disturbed environments favourable to its development. It is now established in the Rhone Valley and a number of different factors (cropping system evolution, climate…
The shell matrix and microstructure of the Ram's Horn squid: Molecular and structural characterization.
2020
20 pages; International audience; Molluscs are one of the most diversified phyla among metazoans. Most of them produce an external calcified shell, resulting from the secretory activity of a specialized epithelium of the calcifying mantle. This biomineralization process is controlled by a set of extracellular macromolecules, the organic matrix. In spite of several studies, these components are mainly known for bivalves and gastropods. In the present study, we investigated the physical and biochemical properties of the internal planispiral shell of the Ram's Horn squid Spirula spirula. Scanning Electron Microscope investigations of the shell reveal a complex microstructural organization. The…
Ultrafiltration as a Means to Investigate Copper Resistance Mechanisms in Soil Bacteria
1999
Copper is a trace element of major concern for agricultural soils. It exhibits a high toxicity against microorganisms and is widely introduced into soils as a component of pesticide treatments or urban wastes such as sewage sludges or refuse composts. In most French vineyards, “Bordeaux mixture” (copper sulfate) has been applied for more than a century, sometimes leading to copper concentrations in soils much higher than the threshold values (100 mg kg−1 in France). Microorganisms exposed to high concentrations of copper or other trace elements are known to develop resistance mechanisms and represent a suitable material for the study of such processes, both at a physiological and molecular …
In situ preservation of local landraces of faba bean (Vicia faba L.) and utilisation of their food products in central regions of Serbia
2012
International audience; Today, faba bean (Vicia faba L.) in Serbia is almost completely replaced with Phaseolus beans and has become a neglected crop with no official data. A recently launched action of the Institute of Field and Vegetable Crops and the Faculty of Agriculture in Novi Sad is aimed at the identification of the regions in Serbia where faba bean, known in Serbian as bob, could still be found. This was essentially enhanced by the multilateral project ECO-NET 18817 Search for new genetic variability in pea (Pisum sativum) and faba bean (Vicia faba L.) to support the development of sustainable agricultures, with duration in 2008 and 2009 and involving partners from France, Bulgari…
En direct de l’essai patrimonial des 42 parcelles d’INRAE à Versailles : impacts de fertilisations centenaires en profondeur du NEOLUVISOL de lœss
2020
International audience; Après l’étude d’évolutions pédologiques et géochimiques dans l’horizon de surface (van Oort et al., 2016, 2017a), ce nouveau volet du projet de valorisation du dispositif des 42 parcelles de l’Inra de Versailles présente les effets d’apports continus de matières fertilisantes à l’échelle du solum, pour une dizaine de traitements : ammoniacaux, engrais-Na et/ou K, phosphatés, CaCO$_3$, fumier et témoins. Pour chaque traitement, les profils de teneur en éléments (0-120 cm) ont été comparés avec le bilan 1929-2014 en surface (0-25 cm), afin de raisonner la pertinence d’études des impacts d’activités anthropiques, restreintes à l’horizon de surface. En l’absence de végét…
Highly resolved observations of trace gases in the lowermost stratosphere and upper troposphere from the Spurt project: an overview
2005
International audience; During SPURT (Spurenstofftransport in der Tropopausenregion, trace gas transport in the tropopause region) we performed measurements of a wide range of trace gases with different lifetimes and sink/source characteristics in the northern hemispheric upper troposphere (UT) and lowermost stratosphere (LMS). A large number of in-situ instruments were deployed on board a Learjet 35A, flying at altitudes up to 13.7 km, at times reaching to nearly 380 K potential temperature. Eight measurement campaigns (consisting of a total of 36 flights), distributed over all seasons and typically covering latitudes between 35° N and 75° N in the European longitude sector (10° W?20° E), …