Search results for "RADIATION"
showing 10 items of 5298 documents
MAPK3 deficiency drives autoimmunity via DC arming.
2010
DC are professional APC that instruct T cells during the inflammatory course of EAE. We have previously shown that MAPK3 (Erk1) is important for the induction of T-cell anergy. Our goal was to determine the influence of MAPK3 on the capacity of DC to arm T-cell responses in autoimmunity. We report that DC from Mapk3(-/-) mice have a significantly higher membrane expression of CD86 and MHC-II and--when loaded with the myelin oligodendrocyte glycoprotein--show a superior capacity to prime naive T cells towards an inflammatory phenotype than Mapk3(+/+) DC. Nonetheless and as previously described, Mapk3(-/-) mice were only slightly but not significantly more susceptible to myelin oligodendrocyt…
MR-Mammographie zur Responsekontrolle bei primärer Chemobrachytherapie des BET-inoperablen Mammakarzinoms
2001
Ziel: Evaluierung (1) moglicher storender Effekte neoadjuvanter Chemobrachytherapie auf die MR-Mammographie, (2) der Eignung der MRM zur Bestimmung der Resttumorgrose nach Therapie und (3) der Eignung der MRM zur Prognose des Gesamtansprechens nach den ersten Therapiezyklen. Methoden: 14 Patientinnen, die an einer praoperativen Tumorreduktionstherapie (4 Zyklen Chemotherapie kombiniert mit interstitieller Radiotherapie) teilnahmen, wurden mittels dynamischer MR-Mammographie (1 T, zeitliche Auflosung 93 s, raumliche Auflosung 1,9 mm, 0,1 mmol/kg GdDTPA) vor Therapie, nach den ersten beiden Chemotherapiezyklen, nach der Radiotherapie und dem dritten Zyklus sowie nach Therapieabschluss untersu…
Inflammatory Murine Skin Responses to UV-B Light Are Partially Dependent on Endothelin-1 and Mast Cells
2006
Endothelin (ET-1) has been shown to crucially contribute to UV-induced skin responses such as tanning. To test whether ET-1 is also involved in early cutaneous reactions to UV, we assessed ET-1 skin levels in UV-irradiated mice. In correlation with the levels of UV-induced skin inflammation, ET-1 concentrations increased substantially and continually. Moreover, blocking of ET-1 receptors (ET A ) resulted in significantly decreased cutaneous inflammation following UV irradiation. When we assessed skin responses to ET-1 injections, we observed prominent mast cell degranulation and mast cell-dependent inflammation. Since mast cells also critically contributed to UV-induced inflammation, we det…
Neutron irradiation defects in gallium sulfide: Optical absorption measurements
1997
Gallium sulfide single crystals have been irradiated with different thermal neutron doses. Defects introduced by neutron irradiation turn out to be optically active, giving rise to absorption bands with energies ranging from 1.2 to 3.2 eV. Bands lying in the band-gap exhibit Gaussian shape. Their energies and widths are independent of the irradiation dose, but their intensities are proportional to it. Thermal annealing is completed in two stages, ending at around 500 and 720 K, respectively. Centers responsible for the absorption bands are proposed to be gallium-vacancy-galliuminterstitial complexes in which the distance between the vacancy (acceptor) and the interstitial (donor) determines…
Vegetation and soil – related parameters for computing solar radiation exchanges within green roofs: Are the available values adequate for an easy mo…
2016
Several studies analyze the thermal performance of vegetated roofs, presenting either mathematical models or experimental quantifications of heat transfer process through them, also showing the effect of vegetation and soil parameters on the thermal and energy performance of this type of roofing system. However, presently the level of availability of these parameters, has not been enough considered. This work intends to investigate this underestimated issue of the green roofs’ thermal modeling, through the consideration of the availability of parameters pertinent to the shortwave radiation exchange, which are adopted by models based on leaf area index (LAI) and on the fractional vegetation …
Integrated three-dimensional models for noninvasive monitoring and valorization of the Morgantina silver treasure (Sicily)
2016
The Morgantina silver treasure belonging to the Archaeological Museum of Aidone (Sicily) was involved in a three-dimensional (3-D) survey and diagnostics campaign for monitoring the collection over time in anticipation of their temporary transfer to the Metropolitan Museum of Art in New York for a period of 4 years. Using a multidisciplinary approach, a scientific and methodological protocol based on noninvasive techniques to achieve a complete and integrated knowledge of the precious items and their conservation state, as well as to increase their valorization, has been developed. All acquired data, i.e., 3-D models, ultraviolet fluorescence, x-ray images, and chemical information, will be…
A PROCEDURE FOR THE EVALUATION OF INSTALLED PROPELLER NOISE
2001
Abstract A method for the prediction of the acoustics of a propeller in the flow-field of a wing is presented. The method is used to study the noise generated by the unsteady loading induced on the propeller as it passes through the wing flow-field. Both the aerodynamic and acoustic methods are previously proven techniques, the aerodynamic method being based on a combination of free wake analysis and a three-dimensional boundary element method, while the acoustic calculation is a full-surface, moving medium form of the Ffowcs Williams–Hawkings equation. Calculations are presented for a reference case of a four-bladed low-speed propeller in forward flight. The acoustic predictions are supple…
An Overview on Solar Shading Systems for Buildings
2014
Abstract In recent years, different types of solar shading devices have been proposed, depending on building orientation, location, window characteristics, etc. They can contribute to improve or worsen building thermal and lighting performances both from an energy and comfort point of view. The present paper reports a critical analysis of some studies that investigate shading devices’ effects on building thermal and/or lighting performances. This article points out the difficulty in comparing the different results given the lack of uniformity between the studies, since they analysed buildings with different characteristics, locations and using various indices. Therefore a protocol to carry …
Transient Modelling of Thermal Conditions in Test Buildings Including Radiation
2015
Abstract To increase the energy efficiency of buildings in Latvia's climate a comparative study with five experimental test buildings have been set up in Riga, Latvia. Different thermo physical quantities such as temperature, humidity, air velocity, etc. were monitored to better understand different behaviour of the building envelope. This gives an excellent validation possibility for the CFD model that in future could predict conditions in buildings with different envelopes. Previously a stationary model and transient model were considered without taking into consideration the thermal radiation. This study continues the previous work that was done and proposes a transient model which takes…
Spin Crossover Systems
2015
Abstract This account constitutes a basic introduction to spin crossover phenomena that is mostly encountered for iron(II) coordination complexes. After briefly describing the occurrence of spin transition in liquid and solid states, the effects of pressure and light irradiation are discussed. Applications and recent trends of this expanding field are also presented.