Search results for "RADIATION"
showing 10 items of 5298 documents
Surface plasmon propagation in metal nanowires
2012
Plasmonic circuitry is considered as a promising solution-effectivetechnology for miniaturizing and integrating the next generation ofoptical nano-devices. The realization of a practical plasmonic circuitry strongly depends on the complete understanding of the propagation properties of two key elements: surface plasmons and electrons. The critical part constituting the plasmonic circuitry is a waveguide which can sustain the two information-carriers simultaneously. Therefore, we present in this thesis the investigations on the propagation of surface plasmons and the co-propagation of surface plasmons and electrons in single crystalline metal nanowires. This thesis is therefore divided into …
Cosmic Dark Radiation and Neutrinos
2013
New measurements of the cosmic microwave background (CMB) by the Planck mission have greatly increased our knowledge about the universe. Dark radiation, a weakly interacting component of radiation, is one of the important ingredients in our cosmological model which is testable by Planck and other observational probes. At the moment, the possible existence of dark radiation is an unsolved question. For instance, the discrepancy between the value of the Hubble constant, H-0, inferred from the Planck data and local measurements of H-0 can to some extent be alleviated by enlarging the minimal ACDM model to include additional relativistic degrees of freedom. From a fundamental physics point of v…
Molecular Dynamics simulation of evaporation processes of fluid bridges confined in slit-like pore
2009
A simple fluid, described by point-like particles interacting via the Lennard-Jones potential, is considered under confinement in a slit geometry between two walls at distance Lz apart for densities inside the vapor-liquid coexistence curve. Equilibrium then requires the coexistence of a liquid "bridge" between the two walls, and vapor in the remaining pore volume. We study this equilibrium for several choices of the wall-fluid interaction (corresponding to the full range from complete wetting to complete drying, for a macroscopically thick film), and consider also the kinetics of state changes in such a system. In particular, we study how this equilibrium is established by diffusion proces…
PSA and PSA Kinetics Thresholds for the Presence of 68Ga-PSMA-11 PET/CT-Detectable Lesions in Patients with Biochemical Recurrent Prostate Cancer
2020
68Ga-PSMA-11 positron-emission tomography/computed tomography (PET/CT) is commonly used for restaging recurrent prostate cancer (PC) in European clinical practice. The goal of this study is to determine the optimum time for performing these PET/CT scans in a large cohort of patients by identifying the prostate-specific-antigen (PSA) and PSA kinetics thresholds for detecting and localizing recurrent PC. This retrospective analysis includes 581 patients with biochemical recurrence (BC) by definition. The performance of 68Ga-PSMA-11 PET/CT in relation to the PSA value at the scan time as well as PSA kinetics was assessed by the receiver-operating-characteristic-curve (ROC) generated by plottin…
Diagnostic Performance of 68Ga-PSMA-11 Positron-emission-tomography/Computed-tomography in a Large Cohort of Patients with Biochemical Recurrence of …
2020
Gallium-68 (Ga) prostate-specific-membrane-antigen positron-emission-tomography/computed-tomography is a highly promising method for imaging primary and recurrent prostate cancer. These dual-modality imaging technologies enable whole-body functional and anatomical evaluation in a single session. This study investigated the performance of Ga-prostate-specific-membrane-antigen-11 positron-emission-tomography/computed-tomography for detecting prostate carcinoma in patients with rising prostate-specific-antigen after primary therapy. Six hundred sixty (660) patients with biochemical recurrence referred for positron-emission-tomography/computed-tomography with Ga-prostate-specific-membrane-antig…
Radiation therapy after radical prostatectomy: what has changed over time?
2021
The role and timing of radiotherapy (RT) in prostate cancer (PCa) patients treated with radical prostatectomy (RP) remains controversial. While recent trials support the oncological safety of early salvage RT (SRT) compared to adjuvant RT (ART) in selected patients, previous randomized studies demonstrated that ART might improve recurrence-free survival in patients at high risk for local recurrence based on adverse pathology. Although ART might improve survival, this approach is characterized by a risk of overtreatment in up to 40% of cases. SRT is defined as the administration of RT to the prostatic bed and to the surrounding tissues in the patient with PSA recurrence after surgery but no …
Minor changes in the macrocyclic ligands but major consequences on the efficiency of gold nanoparticles designed for radiosensitization
2016
International audience; Many studies have been devoted to adapting the design of gold nanoparticles to efficiently exploit their promising capability to enhance the effects of radiotherapy. In particular, the addition of magnetic resonance imaging modality constitutes an attractive strategy for enhancing the selectivity of radiotherapy since it allows the determination of the most suited delay between the injection of nanoparticles and irradiation. This requires the functionalization of the gold core by an organic shell composed of thiolated gadolinium chelates. The risk of nephrogenic systemic fibrosis induced by the release of gadolinium ions should encourage the use of macrocyclic chelat…
The anti-oxidant capacity of tumour glycolysis.
2009
In this mini-review data are summarised which provide evidence for the biological and clinical significance of tumour glycolysis and of its relationship to the redox state of cancer cells.Malignant transformation is associated with an overexpression of numerous glycolysis-related genes in the vast majority of human cancers. At the same time, glycolytic activity and glycolysis-linked metabolic milieu are often variable between individual tumours which induces large variations in treatment response and aggressiveness. Currently, there is no genetic or proteomic marker for the prediction of the therapeutic response for individual tumours, but the prognostic value of tumour lactate accumulation…
Surface soil moisture retrieval using L-band SMAP SAR data and its validation
2016
Surface soil moisture was retrieved globally by systematically correcting for the effects of vegetation and soil surface roughness. The retrieval is enabled by employing physical-models of radar forward scattering for individual vegetation types to account for vegetation scattering and absorption, and by constraining the surface roughness effect using time-series observations. The L-band SMAP multi-polarized (HH/VV/HV) σ° data acquired globally every three days were used from mid-April to early July, 2015. Assessment was conducted over 13 rigorously-chosen core validation sites covering a wide range of biomass types, biomass amount, and soil conditions. The soil moisture retrieval reached a…
Monitoring barley and corn growth from remote sensing data at field scale
2004
Vegetation indices have been used for operational quantitative monitoring of vegetation. Here, corn and barley cultures have been used to relate meaningful biophysical parameters such as dry biomass and Crop Growth Rate (CGR) to the well-established Normalized Difference Vegetation Index (NDVI). We explain these relationships by means of the use of the Light Use Efficiency (LUE) models, based on the positive relation between primary production and Absorbed Photosynthetically Active Radiation (APAR). In these models we introduce NDVI as a linear estimator of f APAR. Experimental data over corn and barley show that dry biomass is linearly related to the Time-Integrated Value of the NDVI (TIND…