Search results for "RAV"

The adenine nucleotide content of rat liver during infusions of carbohydrates and polyols

1972

Injection of large doses of fructose, sorbitol, or a mixture of glucose, fructose and xylitol in rats causes a drop of liver ATP, total adenine nucleotides and Pi and a rise of AMP, which is in agreement with data from the literature. These changes are considered as a transient disturbance of homeostasis by compounds which are rapidly phosporylated in the liver. This is confirmed by the fact that during continuous infusion of these and other compounds at doses of 1,5 g · kg−1 · h−1 there was no such change. It is concluded that infusions of fructose or of the other carbohydrates tested with rates not exceeding those recommended for parenteral nutrition (0,5 g · kg−1 · h−1) are not likely to…

New biodegradable hydrogels based on a photocrosslinkable modified polyaspartamide: synthesis and characterization

1999

Abstract α,β-Poly( N -2-hydroxyethyl)- dl -aspartamide (PHEA), a synthetic water-soluble biocompatible polymer, was derivatized with glycidyl methacrylate (GMA), in order to introduce in its structure chemical residues having double bonds and ester groups. The obtained copolymer (PHG) contained 29 mol% of GMA residues. PHG aqueous solutions at various concentrations ranging from 30 to 70 mg/ml were exposed to a source of UV rays at λ 254 nm in the presence or in the absence of N , N ′-methylenebisacrylamide (BIS); the formation of compact gel phases was observed beginning from 50 mg/ml. The obtained networks were characterized by FT-IR spectrophotometry and swelling measurements which evide…

Biodegradable hydrogels obtained by photocrosslinking of dextran and polyaspartamide derivatives

2003

The functionalization of dextran with glycidyl methacrylate (GMA) leads to the formation of a derivative that generates hydrogels for irradiation at 365nm. The effects of various polymer concentrations and irradiation times on the yield and the properties of the obtained hydrogels are reported. The networks have been characterized by FT-IR spectra, dimensional analysis and swelling measurements carried out at different pH values. In vitro studies suggest that all samples undergo a partial chemical hydrolysis, whereas the incubation with dextranases causes a total degradation whose rate depends on the degree of crosslinking. In addition, aqueous solutions of functionalized dextran have been …

Supramolecular functionalization and concomitant enhancement in properties of Au25 clusters

2014

We present a versatile approach for tuning the surface functionality of an atomically precise 25 atom gold cluster using specific host-guest interactions between ?-cyclodextrin (CD) and the ligand anchored on the cluster. The supramolecular interaction between the Au25 cluster protected by 4-(t-butyl)benzyl mercaptan, labeled Au25SBB18, and CD yielding Au25SBB18�?�CDn (n = 1, 2, 3, and 4) has been probed experimentally using various spectroscopic techniques and was further analyzed by density functional theory calculations and molecular modeling. The viability of our method in modifying the properties of differently functionalized Au25 clusters is demonstrated. Besides modifying their optoe…

Gravity Anomalies Over The Gongola Arm, Upper Benue Trough, Nigeria

2005

A regional gravity survey of the Gongola Arm of the Benue trough was carried out with the aim of determining structures of interest. The results of the gravity interpretation showed that the area of study is characterized by negative Bouguer anomalies that trend in the NE-SW direction and range in value from -75 to -15 mGal with an average of -42 mGal. A first order polynomial was used to approximate the regional anomalies in the area. The residual gravity anomaly map shows anomalies that range in value from -32 to +20 mGal. 2.5-D modeling of the residual gravity anomalies suggests that the area has a horst and graben structure, with the grabens being as large as 60 km in width and filled w…

Inflammation Causes Resistance to Anti-CD20–Mediated B Cell Depletion

2016

B cells play a central role in antibody-mediated rejection and certain autoimmune diseases. However, B cell-targeted therapy such as anti-CD20 B cell-depleting antibody (aCD20) has yielded mixed results in improving outcomes. In this study, we investigated whether an accelerated B cell reconstitution leading to aCD20 depletion resistance could account for these discrepancies. Using a transplantation model, we found that antigen-independent inflammation, likely through toll-like receptor (TLR) signaling, was sufficient to mitigate B cell depletion. Secondary lymphoid organs had a quicker recovery of B cells when compared to peripheral blood. Inflammation altered the pharmacokinetics (PK) and…

OBSERVATIONS OF THE LENSED QUASAR Q2237+0305 WITH CANARICAM AT GTC

2016

We present new mid-IR observations of the quadruply lensed quasar Q2237+0305 taken with CanariCam on the Gran Telescopio Canarias. Mid-IR emission by hot dust, unlike the optical and near-IR emission from the accretion disk, is unaffected by the interstellar medium (extinction/scattering) or stellar microlensing. We compare these "true" ratios to the (stellar) microlensed flux ratios observed in the optical/near-IR to constrain the structure of the quasar accretion disk. We find a half-light radius of $R_{1/2}=3.4_{-2.1}^{+5.3}\sqrt{\langle M \rangle/0.3\,\rm{M_{\odot}}}$ light-days at $\lambda_{rest}=1736$ {\AA}, and an exponent for the temperature profile $R \propto \lambda^{p}$ of $p=0.7…

Valencia vista tomada desde encima de la Puerta del Mar

Menció de responsabilitat i d'impressió original preses de la bibliografia. - Vista panoràmica de la ciutat de València

[Retratos de franceses]

Volum factici de gravats calcogràfics de retrats de personatges francesos Títol pres de la portada manuscrita Gravat calcogràfic en f. de làm

[Retratos de españoles]

Volum factici de gravats calc. de retrats de personatges espanyols Tít. pres de la port. ms Grav. calc. en f. de làm