Search results for "RAV"
showing 10 items of 5866 documents
Understanding Addiction Using Animal Models
2019
Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an extraordinary global economic impact. Despite decades of research, the options available to treat addiction are often ineffective because our rudimentary understanding of drug-induced pathology in brain circuits and synaptic physiology inhibits the rational design of successful therapies. This understanding will arise first from animal models of addiction where experimentation at the level of circuits and molecular biology is possible. We will review the most common preclinical models of addictive behavior and discuss the advantages and disadvantages of each. This includes non-contingent models in whi…
Processi di parenting e di adattamento al ruolo genitoriale in adolescenza
2012
La letteratura mette in risalto come le madri adolescenti incontrino molte difficoltŕ evolutive e di adattamento. La maternitŕ precoce, infatti, si configura come un'interruzione del corso evolutivo normativo delle giovani madri, che affrontano sfide evolutive contemporanee ed incoerenti. Una transizione precoce alla genitorialitŕ, inoltre, comporta, frequentemente, difficoltŕ di adattamento al ruolo parentale, che si manifestano in un incremento consistente dello stress sperimentato durante l'esercizio della funzione genitoriale ed in una compromissione significativa delle competenze parentali. I processi in questione, tuttavia, possono essere compresi adeguatamente soltanto qualora si fac…
Durability of Dolutegravir-Based Regimens: A 5-Year Prospective Observational Study
2021
This study evaluates the frequency and causes of dolutegravir (DTG) discontinuation along 5 years of follow-up, in both antiretroviral treatment (ART)-naive and experienced people living with HIV (PLWH). This is a prospective multi-center cohort study enrolling PLWH on DTG from July 2014 until November 2020. DTG-durability was investigated using the Kaplan-Meier survival curve. The Cox proportional-hazards model was used for estimating the hazard ratio (HR) of DTG discontinuation for any cause, and for adverse events (AEs). Nine hundred sixty-three PLWH were included, 25.3% were women and 28.0% were ART-naive. Discontinuations for any causes were 10.1 [95% confidence interval (95% CI) 8.9-1…
Chronique des sentences du tribunal arbitral des sports de Lausanne
2008
International audience
In particolare: l'aggravante ambientale
2015
Il contributo descrive la nuova aggravante ambientale iscritta all'art 452 nonies del codice penale dalla legge 22 maggio 2015, n. 68
"Je vais être malade de l’amiante, mais l’État, il n’en aura rien à foutre de moi". Ajustements collectifs et individuels aux impensés de la santé au…
2016
International audience
Neighborhood resources associated with active travel in older adults: A cohort study in six European Countries
2020
Objectives: To study associations between perceived neighborhood resources and time spent by older adults in active travel. Methods: Respondents in six European countries, aged 65–85 years, reported on the perceived presence of neighborhood resources (parks, places to sit, public transportation, and facilities) with response options “a lot,” “some,” and “not at all.” Daily active travel time (total minutes of transport-related walking and cycling) was self-reported at the baseline (n = 2,695) and 12–18 months later (n = 2,189). Results: Reporting a lot of any of the separate resources (range B’s = 0.19–0.29) and some or a lot for all four resources (B = 0.22, 95% confidence interval [0.09, …
Entre santé au travail et culture ouvrière : la question du vin ‘‘prolétaire’’ dans la France de l’entre-deux-guerres.
2019
International audience; Depuis l’apparition de la question sociale et le Tableau de l'état physique et moral des ouvriers employés dans les manufactures de coton, de laine et de soie de Villermé en 1840, le monde ouvrier a souvent été stigmatisé par sa misère, sa dangerosité, ses mœurs dissolues et/ou son ivrognerie. Si certains stéréotypes ont disparu, le penchant supposé des ouvriers pour l’alcool, et le vin en particulier, perdure. Ce qui est encore vrai aujourd’hui l’est donc évidemment pour l’entre-deux-guerres.Or, dans le cadre d’une France en pleine mutation économique induite par la seconde révolution industrielle, la législation initiée avec la loi de 1898 sur les accidents du trav…
1988 01 Documentos. 31 congreso federal del PSOE. Madrid, 22-24 enero 1988
2014
Documentos. 31 congreso federal del PSOE contiene los estatutos federales, resoluciones del congreso, censos, delegados al congreso, así como la publicación «1985-1988. Crónica entre congresos», y un dossier de prensa sobre lo que apareció publicado en estas fechas.
1990 11 El XXXII Congreso Federal del PSOE. Madrid. 9-11 de noviembre de 1990
2014
Los socialistas españoles celebraban su XXXII Congreso Federal en Madrid, los días 9, 10 y 11 de noviembre de 1990. En el congreso no habrá debates ideológicos como en los anteriores. Tampoco se debatirá las relaciones UGT-PSOE, pues el asunto está cerrado, y rotos los puentes entre las organizaciones socialistas. El congreso tendría como tema central el modelo de partido: si la Ejecutiva iba a ser más plural, y menos homogénea y disciplinada, es decir menos guerrista, pluralismo frente a «guerrismo»; si se iba a dar entrada en la Ejecutiva a socialistas como Joaquín Almunia, Javier Solana, Joaquín Leguina, Carlos Solchaga, etc., como manifestación de apertura y pluralidad. Y sobre el congr…