Search results for "RCT"

High Arctic aircraft measurements characterising black carbon vertical variability in spring and summer

2019

The vertical distribution of black carbon (BC) particles in the Arctic atmosphere is one of the key parameters controlling their radiative forcing and thus role in Arctic climate change. This work investigates the presence and properties of these light-absorbing aerosols over the High Canadian Arctic (>70∘ N). Airborne campaigns were performed as part of the NETCARE project (Network on Climate and Aerosols: Addressing Key Uncertainties in Remote Canadian Environments) and provided insights into the variability of the vertical distributions of BC particles in summer 2014 and spring 2015. The observation periods covered evolutions of cyclonic disturbances at the polar front, which f…

Polar marine biology science in Portugal and Spain: Recent advances and future perspectives

2013

Xavier, José C. et al.

Eiropas Savienības loma Arktikas reģionā: mērķi un šķēršļi

2017

Maģistra darba tēma ir “Eiropas Savienības loma Arktikas reģionā: mērķi un šķēršļi.” ES ilgstoši izstrādā politiku attiecībā uz Arktikas reģionu, tomēr joprojām nav definējusi skaidrus mērķus un politikas sasniedzamos rezultātus. Darba mērķis ir izpētīt, kādu ārpolitiku ES īsteno attiecībā uz Arktikas reģionu un noskaidrot, vai ES normatīvā ārpolitika attiecībā uz Arktikas reģionu sasniedz mērķus. Maģistra darbā izmantotais teorētiskais pamats ir Iana Mannersa izstrādā normatīvās varas pieeja. Darbā hronoloģiskā secībā tiek analizēta ES noteiktās politikas atbilstība normatīvas ārpolitikas kritērijiem un padziļināti izpētīti ES centieni iegūt novērotāja statusu Arktikas Padomē. Tiek secināt…

Total mercury and methyl-mercury contents and accumulation in polar microbial mats.

2014

Although polar regions are considered isolated and pristine areas, the organisms that inhabit these zones are exposed to global pollution. Heavy metals, such as mercury, are global pollutants and can reach almost any location on Earth. Mercury may come from natural, volcanic or geological sources, or result from anthropogenic sources, in particular industrial or mining activities. In this study, we have investigated one of the most prominent biological non-marine communities in both polar regions, microbial mats, in terms of their Hg and methyl-mercury (MeHg) concentrations and accumulation capacities. The main hypotheses posed argued on the importance of different factors, and to test them…

Polymorphonuclear leukocyte membrane fluidity and cytosolic Ca2+ content in young adults with acute myocardial infarction. Evaluation at the initial …

2004

Our aim was to examine two aspects of polymorphonuclear leukocyte (PMN) rheology (membrane fluidity and cytosolic Ca2+ content), at baseline and after in vitro activation, in a group of young adults with acute myocardial infarction (AMI) at the initial stage and after 12 months. We enrolled 21 AMI subjects aged < or = 45 years (mean age 41.1 +/- 3.5 years) and evaluated PMN membrane fluidity, labelling intact PMN cells with the fluorescent probe 1,4-(trimethylamino)-phenyl-4-phenylhexatriene and the PMN cytosolic Ca2+ content marking PMN cells with the fluorescent probe Fura 2-AM, at baseline and after in vitro activation with 4-phorbol 12-myristate 13-acetate (PMA) and N-formyl-methionyl-l…

Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice

2021

Acute coronary syndrome is a factor for poor prognosis and recurrent cardiovascular events. Adequate antiplatelet therapy is crucial in patients with the acute coronary syndrome for risk reduction. Such treatment is well described in four documents issued by the European Society of Cardiology, which precisely illustrate the use of antiplatelets in the settings of ST-elevated and non-ST elevated myocardial infarction. Despite its unquestioned role in the treatment of acute coronary syndrome, recent real-world-data from Polish registries reveal poor adherence to the guidelines-recommended antiplatelet treatment in Poland. Thus, we present here a comprehensive review of the use of antiplatelet…

New luminescence ages reveal Early to Middle Weichselian deposits in central Latvia

2017

New optically stimulated luminescence (OSL) ages show that sandy deposits overlain by Late Weichselian subglacial till in central Latvia are of Early to Middle Weichselian age. The finer chronological resolution of unconsolidated sediment deposition in the Central Latvian Lowland (CLL) remains relatively unstudied, and here we provide a first characterisation of the deposits with respect to their age. Three OSL ages ranging between 84 ± 9 ka and 112 ± 11 ka suggest that the deposits studied in the CLL are of Early Weichselian age (MIS 5). We found no Middle Weichselian deposits in the CLL, and assume that any such younger sediments might have been eroded during the advance of the Zemgale Lo…

The ESR age of Portlandia arctica shells from glacial deposits of Central Latviaan answer to a controversy on the age and genesis of their enclosing …

1998

Abstract The occurrence of Portlandia arctica shells in glacigenic sediments of Central Latvia had created a controversy in many publications about (1) their age ranging from the Holsteinian to the Late Weichselian and (2) the genesis of their enclosing sediments: glacial, glaciomarine or marine. Our reinvestigation of the main object of controversy, the Licupe site, leads to a conclusion that the sedimentary package of diamictons, clays and sands containing Portlandia arctica shells and marine microfossils is a large glacial raft that had been transported and deposited by the Riga lobe during the Weichselian. The electron spin resonance (ESR) ages on five sets of Portlandia arctica shells …

Latvijas Republikas Satversmei – 95 : Latvijas Universitātes 75. zinātniskās konferences rakstu krājums

2017

Induction of Apoptosis, Autophagy and Ferroptosis by Thymus vulgaris and Arctium lappa Extract in Leukemia and Multiple Myeloma Cell Lines

2020

Thymus vulgaris and Arctium lappa have been used as a folk remedy in the Iraqi Kurdistan region to deal with different health problems. The aim of the current study is to investigate the cytotoxicity of T. vulgaris and A. lappa in leukemia and multiple myeloma (MM) cell lines and determine the mode of cell death triggered by the most potent cytotoxic fractions of both plants in MM. Resazurin assay was used to evaluate cytotoxic and ferroptosis activity, apoptosis, and modulation in the cell cycle phase were investigated via Annexin V-FITC/PI dual stain and cell-cycle arrest assays. Furthermore, we used western blotting assay for the determination of autophagy cell death. n-Hexane, chlorofor…