Search results for "RCT"
showing 10 items of 1934 documents
The diaptomid fauna of Israel (Copepoda, Calanoida, Diaptomidae), with notes on the systematics of Arctodiaptomus similis (Baird, 1859) and Arctodiap…
2014
Background: To date, only scarce information is available about the diaptomid copepods of the Middle East despite the ecological and biogeographical importance of the family Diaptomidae in the inland waters of the Holarctic region. Moreover, the taxonomic status of some of the taxa occurring in the area is in need of revision. We studied crustaceans collected from temporary and permanent lentic water bodies in Israel with the aim of providing an updated census of the diaptomid copepods occurring in the country. Furthermore, we morphologically and genetically analysed samples of Arctodiaptomus similis s.l. to shed light on its taxonomy. Results: Five diaptomid taxa were collected during this…
The phylogenetic position and taxonomic status of Sterechinus bernasconiae Larrain, 1975 (Echinodermata, Echinoidea), an enigmatic Chilean sea urchin
2015
15 pages; International audience; Sterechinus is a very common echinoid genus in benthic communities of the Southern Ocean. It is widely distributed across the Antarctic and South Atlantic Oceans and has been the most frequently collected and intensively studied Antarctic echinoid. Despite the abundant literature devoted to Sterechinus, few studies have questioned the systematics of the genus. Sterechinus bernasconiae is the only species of Sterechinus reported from the Pacific Ocean and is only known from the few specimens of the original material. Based on new material collected during the oceanographic cruise INSPIRE on board the R/V Melville, the taxonomy and phylogenetic position of th…
Phylogenetic analysis of the Antarctic genus Oswaldella Stechow, 1919 (Hydrozoa, Leptomedusae, Kirchenpaueriidae)
1999
A cladistic study was carried out on known species of the characteristically Antarctic genus Oswaldella, adopting as out-groups some other genera included in the family Kirchenpaueriidae. The analysis resulted in a cladogram with low CI in which no relationship between genera can be depicted. However, the hypothesis of monophyly of the genus Oswaldella is corroborated, being supported in our cladogram by five synapomorphies (although all are homoplastic with other taxa or reversed within the species of the genus). The basal relationships of the genus are uncertain, but three species groups are distinguishable within Oswaldella: 1) the O. incognita group, 2) the O. Antarctica group, and 3) a…
Infarctus cérébral et plasticité : focus sur le BDNF
2011
Functional recovery after ischemic stroke largely involves brain plasticity and more accurately its ability to reorganize the neuronal networks spared by the infarct. Studies conducted on animals using different ischemic stroke models have demonstrated that plastic changes are induced by BDNF (Brain-Derived Neurotrophic Factor). Hence, increasing levels of BDNF in the brain is considered a promising therapeutic strategy to reduce post-stroke impairments. In this context, our work had 2 aims: 1) In a rat model, to identify cells involved in the over-production of BDNF and to evaluate the pertinence of the measurement of circulating BDNF levels to estimate brain BDNF levels; 2) In ischemic st…
A 5500-year oxygen isotope record of high arctic environmental change from southern Spitsbergen
2017
The oxygen isotope composition of chironomid head capsules in a sediment core spanning the past 5500 years from Lake Svartvatnet in southern Spitsbergen was used to reconstruct the oxygen isotope composition of lake water (δ18Olw) and local precipitation. The δ18Olw values display shifts from the baseline variability consistent with the timing of recognized historical climatic episodes, such as the Roman Warm Period, the Dark Ages Cold Period and the ‘Little Ice Age’. The highest values of the record, ca. 3‰ above modern δ18Olw values, occur at ca. 1900–1800 cal. yr BP. Three negative excursions increasing in intensity toward the present, at 3400–3200, 1250–1100, and 350–50 cal. yr BP, are…
Coronary chronic total occlusions and mortality in patients with ventricular tachyarrhythmias.
2020
Aims This study sought to assess the prognostic impact of coronary chronic total occlusions (CTO) in patients presenting with ventricular tachyarrhythmias on admission. Methods and results A large retrospective registry was used, including all consecutive patients presenting with ventricular tachyarrhythmias on admission and undergoing coronary angiography from 2002 to 2016. Patients with a CTO were compared with all other patients (non-CTO) for prognostic outcomes. Statistics comprised Kaplan-Meier and Cox regression analyses. Within a total of 1,461 consecutive patients included with ventricular tachyarrhythmias on admission, a CTO was present in 20%. At midterm follow-up of 18 months, th…
Predilation, sizing and post-dilation scoring in patients undergoing everolimus-eluting bioresorbable scaffold implantation for prediction of cardiac…
2017
Aims: The aim of the study was to develop a scoring model to evaluate the quality of bioresorbable vascular scaffold (BVS) implantation and determine the model's usefulness in predicting adverse cardiac events. Methods and results: The implantation technique and clinical outcomes of 1,736 lesions treated with BVS were analysed using the GHOST-EU registry. Predilation, scaffold sizing, and post-dilation (PSP) were scored according to the hazard model derived from the weight of these variables. The primary end-point was a one-year device-oriented composite endpoint (DoCE) composed of cardiac death, target vessel myocardial infarction, and clinically driven target lesion revascularisation. Def…
Twelve-month outcomes after bioresorbable vascular scaffold implantation in patients with acute coronary syndromes. Data from the European Multicente…
2017
The aim of this study was to report on the midterm outcomes of patients undergoing percutaneous coronary intervention with bioresorbable vascular scaffolds (BVS) for the treatment of acute coronary syndromes (ACS) and compare with those of patients with stable coronary artery disease (sCAD).One thousand four hundred and seventy-seven (1,477) patients underwent implantation of one or more BVS (Absorb BVS; Abbott Vascular, Santa Clara, CA, USA) at 11 European centres and were included in the GHOST-EU registry. Admissions comprised 47.1% of the patients (951 BVS) with ACS, and 52.8% (1,274 BVS) with sCAD. During a median follow-up of 384 (359-460) days, patient-oriented endpoints (PoCE), inclu…
Clinical outcomes of patients with diabetes mellitus treated with Absorb bioresorbable vascular scaffolds: a subanalysis of the European Multicentre …
2017
Background Data on the clinical performance of bioresorbable scaffolds in patients with diabetes mellitus (DM) are still limited. The present study reported 1-year clinical outcomes associated with the use of everolimus-eluting bioresorbable vascular scaffolds (Absorb BVS; Abbott Vascular, Santa Clara, CA) in DM patients. Methods and Results This was a subanalysis from the GHOST-EU (Gauging coronary Healing with biOresorbable Scaffolding plaTforms in Europe) multicenter retrospective registry including patients treated with Absorb BVS between November 2011 and September 2014. In this study, a comparative analysis stratified according to DM was performed. The primary endpoint was target lesi…
Rational and design of the European randomized Optical Coherence Tomography Optimized Bifurcation Event Reduction Trial (OCTOBER)
2018
Background Percutaneous coronary intervention in complex bifurcation lesions is prone to suboptimal implantation results and is associated with increased risk of subsequent clinical events. Angiographic ambiguity is high during bifurcation stenting, but it is unknown if procedural guidance by intravascular optical coherence tomography (OCT) improves clinical outcome. Methods and design OCTOBER is a randomized, investigator-initiated, multicenter trial aimed to show superiority of OCT-guided stent implantation compared to standard angiographic-guided implantation in bifurcation lesions. The primary outcome measure is a 2-year composite end point of cardiac death, target lesion myocardial inf…