Search results for "REGION"
showing 10 items of 4910 documents
Synthetic microbiology as a source of new enterprises and job creation: a Mediterranean perspective
2019
Peer reviewed
Low back pain, work absenteeism, chronic back disorders, and clinical findings in the low back as predictors of hospitalization due to low back disor…
2005
Study Design. Prospective cohort study. Objective. To study symptoms, chronic disorders, and clinical findings in the low back, and work absenteeism, as predictors of hospitalization. Summary of Background Data. Socioeconomic and lifestyle factors are associated with back-related hospitalization, but the significance in the working normal population of low back symptoms and clinical findings are not known. Methods. The cohort (n = 902) was drawn in 1973 from among employees in the metal industry (n = 2,653). The data were collected by questionnaire and a structured clinical assessment by a physiotherapist. Weight was measured. A sum score of local and radiating low back symptoms (frequency …
Marchés du travail et disparités régionales en Pologne
2001
This article evaluates empirically the effect o f market introduction on the level o f regional inequalities and on the polarisation o f economic activities in Poland. We note an increase o f the disparities between regions over the relevant period. The re-polarisation process cannot been explained by a spatial re-allocation of labour force but rather results o f the differentiation of sectoral restructuring between regions the regional diversity o f sectoral adaptation. The search for agglomeration economies explains the spatial concentration o f services and o f added value in the regions where the biggest cities are located. A cumulative process o f agglomeration is observed. Therefore, …
Persistence of low back pain reporting among a cohort of employees in a metal corporation: A study with 5-, 10-, and 28-year follow-ups
2005
Low back pain (LBP) is a common symptom among adults but little is known about its persistence over time in defined populations. The aim of this study was to examine the persistence of LBP among a cohort of industrial employees studied in four successive surveys during a total of 28 years. Cross-tabulations and logistic regression was used to estimate the interdependence of LBP occurrence at the surveys. At baseline, 54% of the subjects reported local LBP and 25% LBP radiating to the lower limb(s). Persistent or recurrent LBP was common. Of those with LBP at baseline, 75, 73, and 88% reported it also at the 5-, 10- or 28-year follow-up, respectively. Of those with radiating pain, 66, 65, an…
Functional interaction of estrogen receptor α and caveolin isoforms in neuronal SK-N-MC cells
2003
Estrogen receptors (ERs) are expressed in neuronal cells and exhibit a wide variety of activities in the central nervous system. The actions of ERs are regulated in a hormone-dependent manner as well as by a number of co-activators and -repressors. A recently identified co-activator of ERalpha is caveolin-1 which has been shown to mediate the ligand-independent activation of this steroid receptor. In the present study we have demonstrated that neuronal SK-N-MC cells lacking functional ERalpha show high levels of caveolin-1/-2 specific transcripts and proteins. Ectopic expression of ERalpha in SK-N-MC cells leads to the transcriptional suppression of caveolin-1 and -2 genes. This silencing e…
Dopamine agonist cabergoline reduces hemoconcentration and ascites in hyperstimulated women undergoing assisted reproduction.
2007
Abstract Context: Ovarian hyperstimulation syndrome (OHSS) results from increased vascular permeability (VP) caused by ovarian hypersecretion of vascular endothelial growth factor (VEGF), which activates its receptor-2. In animals, the dopamine receptor 2 agonist cabergoline (Cb2) inactivates VEGF receptor-2 and prevents increased VP. Objective: Our objective was to test whether Cb2 reduces VP and prevents OHSS in humans. Design: We conducted a prospective, randomized, double-blind study on oocyte donors at risk of developing OHSS (>20 follicles, >12 mm developed, and >20 oocytes retrieved). Interventions: Cb2 0.5 mg/d (n = 37) or a placebo (n = 32) was administered fro…
Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants.
1998
Although nitric oxide (NO) and antioxidants inhibit adhesion molecule expression, their inhibitory effects on nuclear factor kappaB (NF-kappaB) activation may differ. The NO donors, but not 8-bromo-cGMP, decreased tumor necrosis factor alpha (TNF-alpha)-induced VCAM-1, ICAM-1, and E-selectin expression by 11-70%. In contrast, NAC completely abolished VCAM-1 and E-selectin expression and decreased ICAM-1 expression by 56%. Gel shift assays demonstrate that NF-kappaB activation was inhibited by both NO and antioxidants. The activation of NF-kappaB involves the phosphorylation and degradation of its cytoplasmic inhibitor IkappaB-alpha by 26S proteasomes. The 26S proteasome inhibitor MG132 prev…
Automatic research of the capitalization rate for the residential automated valuation: an experimental study in Cosenza (Italy).
2017
When a market oriented approach is not applicable because of the lack of comparable sales data (Ciuna et al. 2014a), International Valuation Standards suggest the use of the Income Approach, which has the task of simulating the market through an economic and financial scheme. The central question of this approach is due to the quantification of the capitalization rate, whereas it is generally extracted in a market segment different from that of the subject. This paper intends to propose an automated valuation model of the capitalization rate based on a real estate database built through a computerized geocoding automatic procedure, starting from the application of statistical models of mult…
Farm Cultural Park : An Experience of Social Innovation in the Recovery of the Historical Centre of Favara
2017
In 2010 some people from Favara decided to initiate a process of recovery and re-appropriation of the abandoned historical centre, by establishing Farm Cultural Park, a private cultural institution. This paper aims to describe the process of sustainable design, social innovation and inclusion, triggered by the Farm Cultural Park in the historical centre of Favara which, by showing its resilience, has redefined its identity, progressing from a place of widespread, unauthorised development to a dynamic creative city.
From Silk to Digital Technologies: A Gateway to New Opportunities for Creative Industries, Traditional Crafts and Designers. The SILKNOW Case
2020
Nowadays, cultural heritage is more than ever linked to the present. It links us to our cultural past through the conscious act of preserving and bequeathing to future generations, turning society into its custodian. The appreciation of cultural heritage happens not only because of its communicative power, but also because of its economic power, through sustainable development and the promotion of creative industries. This paper presents SILKNOW, an EU-H2002 funded project and its application to cultural heritage, as well as to creative industries and design innovation. To this end, it presents the use of image recognition tools applied to cultural heritage, through the interoperability of …