Search results for "REGION"

Scalp psoriasis: report of efficient treatment with secukinumab

2018

Background: Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the population in the world. The scalp is the most common, and frequently the first site of disease involvement. Occasionally it may be the only localization of psoriasis. Objective: Treatment of scalp psoriasis is often unsatisfactory, due to limited available topical therapy and reduced efficacy of some systemic drugs. Biologic therapies are recommended for severe psoriasis, resistant to topical treatment, but evidence from randomized, controlled studies is lacking regarding effectiveness on scalp-localized lesions. The aim of this paper is to show our experience on the efficacy of secukinumab on scalp psoriasi…

Considerations on the Advantages and Disadvantages of Romania's Accession to the European Union

2015

Abstract After nine years from Romania's accession to the European Union, the advantages are sustained with specific statistical markers, which could have been more positive if the effect of certain identified causes (reduced administrative ability, political instability, extended corruption, high tax evasion etc.) would have been diminished. Counterbalancing the benefits of the accession the opinion polls show the disadvantages. If a poll conducted four years prior to the accession showed that 66% of Romania's population considered that the accession to the European Union would produce positive effects, after six years from the accession things have reversed and 58% of Romanians considered…

Disparités géographiques et convergence des régions européennes : une approche par l'économétrie spatiale

2002

The aim of this dissertation is to analyze the convergence process between European regions by taking into account spatial patterns of economic activities. First, with the help of literature reviews on theoretical and empirical analyses of growth and convergence and on economic geography models, we show in chapter 1 why geographic disparities should be introduced in the study of convergence between economies. Next, the spatial statistic and econometric tools allowing to reach this goal are detailed in chapter 2. Finally, three empirical studies of the convergence process in presence of geographic disparities are carried out. They are based on a sample for per capita GDP of 138 regions, belo…

Kokkolan vesipiiristä Keski-Pohjanmaan ympäristökeskukseksi : ympäristöhallinnon elämänkaari maakuntalehdissä

2001

Manoeuvring between regulations to achieve locally accepted results : analysis of school meals in Latvia and Finland

2018

Rather than having a consistent food policy, countries often tend to regulate food from the margins of other policy domains such as agricultural, environmental, welfare or educational policies. Regulatory interventions perceive food as an instrument rather than a domain with its own specific set of policy issues and view food provision as an activity to achieve certain economic, social and environmental objectives. This fragments the food policy into disintegrated points of interventions from various policy areas and leaves unregulated voids that can be exploited either to improve or to reduce the effectiveness of the interventions. This article explores interlinkages between fragmented pol…

Algunas reflexiones sobre la novela de la emigración italiana en Argentina

2015

Por ser una de las metas migratorias que gran parte de los emigrantes italianos eligieron, Argentina constituye un importante punto de referencias culturales, fruto de una evidente 'transculturación'. La amplia cantidad de publicaciones sobre el tema migratorio facilita la localización de referencias ejemplares, por la variedad de situaciones presentadas y por la relación privilegiada entre emigrante, entorno e historia. Eso permite entrar en la dialéctica permanente de una nueva construcción cultural y social que se basa en la identidad múltiple. Being one of the privileged destinations for Italian emigrants, Argentina represents a momentous result of some of the most meaningful issues of …

Molecular Approaches Fighting Nonsense

2021

Nonsense mutations are the result of single nucleotide substitutions in the DNA that change a sense codon (coding for an amino acid) to a nonsense or premature termination codon (PTC) within the coding region of the mRNA [...]

Inflammation and impaired endothelium-dependant vasodilatation in non obese women with gestational diabetes mellitus: preliminary results

2013

International audience; BACKGROUND: To evaluate whether abnormal endothelial function, a common finding in gestational diabetes mellitus (GDM) pregnancies, can be explained by inflammatory cytokines. METHODS: Forearm skin blood flow (FSBF), into response to acetylcholine (Ach) (endothelium-dependent vasodilatation), were measured in 24 pregnant control subjects and 28 gestational diabetes mellitus (GDM) women, in the third trimester of gestation. A fasting glycemic and lipidic panel was obtained, and inflammatory cytokines (TNF-alpha and IL-6) and adiponectin were also determined. RESULTS: FSBF is significantly reduced in GDM group compared with control subjects (344.59 +/- 57.791 vs.176.38…

Mycotoxins and their consequences in aquaculture: A review

2016

Fish consumption has been increasing worldwide, mainly due to the availability, access and price in relation to other kinds of meat consumption, such as beef, pork, and poultry. Consequently, some concerns begin to emerge, primarily regarding the quality of fish available in the market. Residues could be present in any product of animal origin causing economic losses and putting into a risk human and animal health. Food contamination by mycotoxins is a risk to human and animal health, and it is responsible for significant economic losses. It's very difficult to prove that a disease is a mycotoxicosis, and even when mycotoxins are detected, it is not easy to show that they are the etiologica…

Some aspects related to stability, critical concentrations and kinetics of flocculation of the calcium phytate colloid

1986

Abstract As 99mTcCa phytate is an important radiopharmaceutical and its colloidal nature presents problems, we investigated some of them. This work describes the study of the colloidal behaviour of the calcium phytate colloid in terms of its formation, stability and kinetics of flocculation. The study of spontaneous, and centrifugation-induced flocculation allows the determination of two critical concentrations of sol flocculation. The titrations of calcium phytate colloid at different concentrations provide information on the colloidal formation conditions. Moreover, a study on flocculation kinetics was made by turbidity measurements.