Search results for "REGULATION"
showing 10 items of 4463 documents
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.
2008
Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …
Comments on Art. 35
2022
This comment deals with Art. 35 of Regulation (EU) 2015/848 and, more specifically, with the law which is applicable to secondary insolvency proceedings.
Apzinātība, emociju regulācija un pašefektivitāte Iespējamās Misijas un citu augstāko izglītību pedagoģijā ieguvušiem skolotājiem.
2016
Pētījuma mērķis bija noskaidrot, vai pastāv atšķirības starp Iespējamās Misijas skolotāju un Latvijas Universitātes topošo skolotāju apzinātības, pašefektivitātes un emociju regulācijas rādītājiem, kā arī, kādas saistības pastāv starp šiem trim mainīgajiem. Datu ievākšanai tika izmantotas 3 aptaujas: Emociju regulācijas aptauja (Emotion Regulation Questionnaire /ERQ/, Gross & John, 2003). Latvijā instrumenta sākotnējā adaptācija tika veikta maģistra darba ietvaros (Morozova, 2011); Norvēģu skolotāju pašefektivitātes skala (Norwegian Teacher Self-Efficacy Scale jeb NTSES (Skaalvik & Skaalvik, 2007)). Latviešu valodā sākotnējā versija adaptēta kursa darba ietvaros (Virse, 2015); Apzinātības p…
Psicobiologia dell'attaccamento
2008
In this work, the emotional and cerebral development of the individual is treated as a complex process, within which genetic and experiential factors interact; equal focus is given to these factors as is through the interactions of both that the human brain achieves full maturity. The recent literature on neuroscientific findings has allowed to understand further which are the mechanisms that play the most important role in the human brain. In particular, this recent work has pointed out the importance of precocious experiences of emotional syntonization between the baby and its development partners; the quality of the experiences that such partners will be able to provide will configure no…
L'attività normativa del governo nel periodo 2017-2019
2022
L’articolo descrive l’attività normativa del governo nel periodo 2017-2019. Per quanto riguarda le procedure di programmazione e revisione della spesa pubblica, le riforme del 2016 finalizzate alla riduzione della spesa dei Ministeri hanno trovato applicazione solo nel 2017, mentre nel 2018 e nel 2019 ulteriori risparmi sono stati conseguiti mediante apposite previsioni delle leggi di bilancio. Le principali innovazioni in materia di liberalizzazione sono state portate a termine nel 2017, mentre non vi sono stati interventi rilevanti nel biennio successivo. Per quanto concerne il decentramento di funzioni amministrative, non si sono riscontrati progressi. Le politiche di privatizzazione son…
Nuevas perspectivas de la política y del derecho audiovisual
1999
Cuando constatamos, en tiempos de presente y futuro, la realidad y perspectivas del sector audiovisual en el marco de la UE podemos advertir la importancia e influencia de este sector en la construcción europea. Basta, para ello, apelar a tres tipos de razones: el gran auge y crecimiento que está experimentando este sector, tanto en inversión como en creación de empleos, en estos momentos y que todavía será mayor en el siglo XXI -con todo lo que implica en el aumento del peso específico de este sector en el conjunto de la economía comunitaria-; la gran transformación que está experimentando este sector con el tránsito de la tecnología analógica hacia la tecnología digital y que va a suponer…
The increase in maternal expression of axin1 and axin2 contribute to the zebrafish mutant ichabod ventralized phenotype.
2014
β-Catenin is a central effector of the Wnt pathway and one of the players in Ca(+)-dependent cell-cell adhesion. While many wnts are present and expressed in vertebrates, only one β-catenin exists in the majority of the organisms. One intriguing exception is zebrafish that carries two genes for β-catenin. The maternal recessive mutation ichabod presents very low levels of β-catenin2 that in turn affects dorsal axis formation, suggesting that β-catenin1 is incapable to compensate for β-catenin2 loss and raising the question of whether these two β-catenins may have differential roles during early axis specification. Here we identify a specific antibody that can discriminate selectively for β-…
Banche e mercato del credito in Italia: tendenze di mercato, prospettive regolamentari e processi di disintermediazione.
2020
Il capitolo vuole fornire alcuni spunti di riflessione sulle tendenze del mercato del credito in Italia e sulle nuove prospettive regolamentari, in relazione alle innovazioni di carattere istituzionale e di mercato in atto nel sistema bancario italiano, adottando una prospettiva di osservazione che è quella dell’economia della banca. Nella prima parte saranno illustrate le dinamiche che hanno contrassegnato il mercato del credito italiano, nonché i principali profili gestionali relativi ai crediti deteriorati. Nella seconda parte saranno esaminati gli impatti sul mercato del credito delle nuove regole di vigilanza prudenziale, delle nuove regole contabili e sul capitale delle banche, i proc…
Crisi economica e vigilanza unica europea sulle banche: alcuni riflessi sul mercato dei servizi finanziari.
2015
This paper aims to examine some significant implications of the new European single banking supervision for the economics of banking and the market of financial services. It is one of the three pillars of the European Banking Union architecture, as part of a longer term vision for further economic and monetary integration in EU. The new supervisory mechanisms implies a huge and complex transfer of powers from national authorities to the European Central Bank. It aims to ensure the safety and soundness of the European banking system, increase financial integration and stability, and ensure consistent supervision. Banks are being held to common supervisory standards. The structure of this pap…
Theory and regulation of liquidity risk management in banking
2016
Liquidity risk is now more important than it used to be in the past. The financial crisis has emphasised the importance of liquidity risk to the functioning of banking and financial system. The paper presents a theoretical and regulatory investigation of two types of liquidity risk: funding liquidity risk and market liquidity risk. The paper analyses the different approaches to measure the impact of funding and market liquidity risk in the economics and management of banks. The paper provides also an analysis of the organisational implications of the asset and liability management perspective of liquidity risk. Liquidity risk does not need to be covered by equity but by an adequate volume o…