Search results for "RELATION"

Genetic Determinants in a Critical Domain of NS5A Correlate with Hepatocellular Carcinoma in Cirrhotic Patients Infected with HCV Genotype 1b

2021

HCV is an important cause of hepatocellular carcinoma (HCC). HCV NS5A domain-1 interacts with cellular proteins inducing pro-oncogenic pathways. Thus, we explore genetic variations in NS5A domain-1 and their association with HCC, by analyzing 188 NS5A sequences from HCV genotype-1b infected DAA-naïve cirrhotic patients: 34 with HCC and 154 without HCC. Specific NS5A mutations significantly correlate with HCC: S3T (8.8% vs. 1.3%, p = 0.01), T122M (8.8% vs. 0.0%, p &lt

Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms

2010

Background— Cholesteryl ester transfer protein (CETP) inhibitors raise high-density lipoprotein (HDL) cholesterol, but torcetrapib, the first-in-class inhibitor tested in a large outcome trial, caused an unexpected blood pressure elevation and increased cardiovascular events. Whether the hypertensive effect resulted from CETP inhibition or an off-target action of torcetrapib has been debated. We hypothesized that common single-nucleotide polymorphisms in the CETP gene could help distinguish mechanism-based from off-target actions of CETP inhibitors to inform on the validity of CETP as a therapeutic target. Methods and Results— We compared the effect of CETP single-nucleotide polymorphisms …

Les relations des Eglises et de l'Etat : un compromis permanent

2007

Organització social i atenció mèdica a la Cocentaina baixmedieval: el procés a Abrahim Abengalell (1318)

2005

In the bordering judicial courts of the valencian Kingdom could be seen a characteristic fellowship between christian and jewish sanitary practitioners, who attended patients, men and women, that belonged to both religions, in the same professional practice where a new system based on the academic medicine was being developed.

Transcendental Idealism and Strong Correlationism: Meillassoux and the End of Heideggerian Finitude

2014

Tutkimus lastensuojelun tukihenkilötoiminnan muutoksista : relationaalinen näkökulma

2015

Apmierinātības ar partnerattiecībām saistība ar histēriskas personības iezīmēm

2019

Bakalaura darba pētījuma mērķis bija noskaidrot, vai pastāv saistība starp apmierinātību ar partnerattiecībām un histēriskas personības iezīmju izteiktību. Lai šo mērķi sasniegtu, tika izvirzīts pētījuma jautājums – kāda saistība pastāv starp apmierinātību ar partnerattiecībām un histēriskas personības iezīmju izteiktību? Lai atbildētu uz pētījuma jautājumu, tika veikta literatūras analīze un veikts pētījums. Pētījumā piedalījās 70 respondenti vecumā no 20 līdz 49 gadiem (vidējais vecums 27,20 gadi), kuri ir romantiskās attiecībās no 2 mēnešiem līdz 18 gadiem (vidējais attiecību ilgums 3,83 gadi). Datu iegūšanai tika izmantota “Attiecību novērtēšanas skala” (Relationship Assessment Scale (H…

Responsibility in home-school relations : Finnish parents' views

2014

Finnish parents' views on responsibility in the home–school relations were explored. Responsibility was here understood as responsibility over education and upbringing. The data consist of semi-structured interviews with 24 mothers and four fathers. In the home–school discourses, parents and teachers were often referred to as partners, and active parental involvement in school life was seen as a key to children's success. However, in some discourses teachers and parents were seen as polar opposites, e.g. teachers as experts — parents as laymen. Few references were made to children's responsibility.

Adopción en casos especiales y unidad del status filiationis en el derecho italiano: ¿cómo repercute en el plano sucesorio?

2022

In the Italian legal system, there has recently been recognition by the Constitutional Court in adoptions in particular cases of the existence of civil relations between the adoptee and the relatives of the adopter, thus equalizing the margins of protection of minors, regardless of the situations of fact or law from which the new status of the child originated. This jurisprudential work is full of considerable systematic reflections and is intended to be applied not only to the hypothesis of adoption by same-sex couples, but also to all those cases in which a state of semi-permanent abandonment or cyclical abandonment occurs. Notwithstanding the negative value directed at the forms of surro…

Employer Brand Role in HR Recruitment and Selection

2015

Abstract This paper’s research focuses on employer brand (EB) development as a solution for public sector organizations to attract the young specialists of Latvia. The author uses monographic research method, selection, comparison, induction and statistical data interpretation to explore the situation and potential outcomes of the proposed approach to Human Resource Recruitment and Selection. The research results show that public organizations in Latvia still need to improve their positioning on labour market and work harder on their EB.