Search results for "RET"

showing 10 items of 32883 documents

Novel Stannatrane N(CH2CMe2O)2(CMe2CH2O)SnO-t-Bu and Related Oligonuclear Tin(IV) Oxoclusters. Two Isomers in One Crystal

2016

The syntheses of the alkanolamine N(CH2CMe2OH)2(CMe2CH2OH) (1), of the stannatrane N(CH2CMe2O)2(CMe2CH2O)SnO-t-Bu (2), and of the trinuclear tin oxocluster 3 consisting of the two isomers [(μ3-O)(O-t-Bu){Sn(OCH2CMe2)(OCMe2CH2)2N}3] (3a) and [(μ3-O)(μ3-O-t-Bu){Sn(OCH2CMe2)(OCMe2CH2)2N}3] (3b) as well as the isolation of a few crystals of the hexanuclear tin oxocluster [LSnOSn(OH)3LSnOH]2 [L = N(CH2CMe2O)2(CMe2CH2O)] (4) are reported. The compounds were characterized by 1H, 13C, 15N, and 119Sn (1–3) nuclear magnetic resonance and infrared spectroscopy, electrospray ionization mass spectrometry, and single-crystal X-ray diffraction analysis (1–4). A graph set analysis was performed for compoun…

010405 organic chemistryChemistryElectrospray ionizationAnalytical chemistryInfrared spectroscopychemistry.chemical_element010402 general chemistry01 natural sciencesGraph0104 chemical sciencesInorganic ChemistryCrystalCrystallographychemistry.chemical_compoundDensity functional theoryAlkanolaminePhysical and Theoretical ChemistryTinInorganic Chemistry
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Photochemically Produced Singlet Oxygen: Applications and Perspectives

2018

This Review aims to provide early stage researchers with an updated guide to applications of photochemically produced singlet oxygen and, at the same time, widen the experienced researcher's perspectives in a holistic approach to singlet oxygen chemistry. Without being exhaustive, literature between 2010 and early 2018 has been surveyed by focusing on a critical evaluation of new knowledge and applications. After an introductory section concerning singlet oxygen production, detection, and interactions with biological systems, subsequent sections describe current applications of singlet-oxygen-enabled technology. Besides strictly chemical synthesis applications, attention has been given to t…

010405 organic chemistryChemistryEnvironmental remediationSinglet oxygenmedicine.medical_treatmentOrganic ChemistryPhotodynamic therapySettore CHIM/06 - Chimica Organica010402 general chemistryPhotochemistry01 natural sciencessinglet oxygen0104 chemical sciencesAnalytical Chemistryphotooxygenation reactionchemistry.chemical_compoundphotodynamic therapymedicinePhysical and Theoretical Chemistryenvironmental remediationphototherapy
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Mechanism of activated chemiluminescence of cyclic peroxides: 1,2-dioxetanes and 1,2-dioxetanones

2017

Almost all chemiluminescent and bioluminescent reactions involve cyclic peroxides. The structure of the peroxide and reaction conditions determine the quantum efficiency of light emission. Oxidizable fluorophores, the so-called activators, react with 1,2-dioxetanones promoting the former to their first singlet excited state. This transformation is inefficient and does not occur with 1,2-dioxetanes; however, they have been used as models for the efficient firefly bioluminescence. In this work, we use the SA-CASSCF/CASPT2 method to investigate the activated chemiexcitation of the parent 1,2-dioxetane and 1,2-dioxetanone. Our findings suggest that ground state decomposition of the peroxide com…

010405 organic chemistryChemistryGeneral Physics and Astronomy010402 general chemistryPhotochemistrySupermolecule01 natural sciencesPeroxideLUCIFERIDAE0104 chemical scienceslaw.inventionchemistry.chemical_compoundlawExcited stateBioluminescenceLight emissionSinglet statePhysical and Theoretical ChemistryGround stateChemiluminescencePhysical Chemistry Chemical Physics
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Thorough evaluation of OECD principles in modelling of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives using QSARINS.

2020

The human immunodeficiency virus is a lethal pathology considered as a worldwide problem. The search for new strategies for the treatment of this disease continues to be a great challenge in the scientific community. In this study, a series of 107 derivatives of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine, previously evaluated experimentally against HIV-I reverse transcriptase, was used to model antiretroviral activity. A model of linear regression, implemented in the QSARINS software, was developed with a genetic algorithm for variable selection. The fit of its parameters was good and exhaustive validation, according to the OECD regulatory principles, was performed. Also, the applica…

010405 organic chemistryChemistryHuman immunodeficiency virus (HIV)Quantitative Structure-Activity RelationshipBioengineeringGeneral Medicinemedicine.disease_cause01 natural sciencesVirologyReverse transcriptase0104 chemical sciences010404 medicinal & biomolecular chemistryAnti-Retroviral AgentsModels ChemicalDrug DiscoverymedicineMolecular Medicine1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymineOrganisation for Economic Co-Operation and DevelopmentThymineSAR and QSAR in environmental research
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Identification and H(D)-bond energies of C-H(D)Cl interactions in chloride-haloalkane clusters: a combined X-ray crystallographic, spectroscopic, and…

2016

The cationic (1,3,5-triazapentadiene)Pt(II) complex [Pt{NH[double bond, length as m-dash]C(N(CH2)5)N(Ph)C(NH2)[double bond, length as m-dash]NPh}2]Cl2 ([]Cl2) was crystallized from four haloalkane solvents giving [][Cl2(CDCl3)4], [][Cl2(CHBr3)4], [][Cl2(CH2Cl2)2], and [][Cl2(C2H4Cl2)2] solvates that were studied by X-ray diffraction. In the crystal structures of [][Cl2(CDCl3)4] and [][Cl2(CHBr3)4], the Cl(-) ion interacts with two haloform molecules via C-DCl(-) and C-HCl(-) contacts, thus forming the negatively charged isostructural clusters [Cl(CDCl3)2](-) and [Cl(CHBr3)2](-). In the structures of [][Cl2(CH2Cl2)2] and [][Cl2(C2H4Cl2)2], cations [](2+) are linked to a 3D-network by a syste…

010405 organic chemistryChemistryHydrogen bondGeneral Physics and Astronomychloride-haloalkane clustersCrystal structure010402 general chemistry01 natural sciences0104 chemical sciencesIonCrystalCrystallographyhydrogen bondsCluster (physics)MoleculePhysical and Theoretical ChemistryBond energyIsostructuralta116Physical chemistry chemical physics : PCCP
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Photochemistry and Redox Chemistry of an Unsymmetrical Bimetallic Copper(I) Complex

2016

The bimetallic copper(I) complex Cu2L2 (cis-1) is formed with high diasteroselectivity from [Cu(NCCH3)4][BF4] and HL (4-tert-butyl phenyl(pyrrolato-2-yl-methylene)amine) in a kinetically controlled reaction. cis-1 features a rather short Cu···Cu distance of 2.4756(6) A and is weakly emissive at room temperature in solution. Oxidatively triggered disproportionation of cis-1 yields elemental copper and the mononuclear copper(II) complex CuL2 (trans-2). One-electron reduction of trans-2 gives cuprate [2]– with a bent bis(pyrrolato) coordinated copper(I) entity. The imine donor atoms of [2]– can insert an additional copper(I) ion giving exclusively the bimetallic complex cis-1 closing the oxida…

010405 organic chemistryChemistryIminechemistry.chemical_elementDisproportionation010402 general chemistryPhotochemistry01 natural sciencesRedoxCopper0104 chemical sciencesIonInorganic Chemistrychemistry.chemical_compoundAmine gas treatingCupratePhysical and Theoretical ChemistryBimetallic stripInorganic Chemistry
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On the Road to MM′X Polymers: Redox Properties of Heterometallic Ni···Pt Paddlewheel Complexes

2014

On the quest of heterometallic mixed-valence MM'X chains, we have prepared two stable discrete bimetallic compounds: the reduced (PPN)[ClNi(μ-OSCPh)4Pt] (PPN = bis(triphenylphosphine)iminium; OSCPh = benzothiocarboxylato) and the oxidized [(H2O)Ni(μ-OSCPh)4PtCl] species. The role of the aqua and chlorido axial ligands is crucial to facilitate oxidation of the {Ni(μ-OSCPh)4Pt} core. Experimental and theoretical analyses indicate that a NiPt-Cl/Cl-NiPt isomerization process occurs in the oxidized species. The electronic structure of the reduced system shows two unpaired electrons, one located in a d(x(2)-y(2)) orbital of the Ni(II) ion and a second in the antibonding d(z(2)-dz(2)) combination…

010405 organic chemistryChemistryIminium010402 general chemistryPhotochemistryAntibonding molecular orbital01 natural sciencesRedox0104 chemical sciencesInorganic ChemistryCrystallographychemistry.chemical_compoundUnpaired electron[CHIM]Chemical SciencesMolecular orbitalPhysical and Theoretical ChemistryTriphenylphosphineBimetallic stripIsomerizationComputingMilieux_MISCELLANEOUS
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Electrochemical, Spectroelectrochemical, and Structural Studies of Mono- and Diphosphorylated Zinc Porphyrins and Their Self-Assemblies

2019

International audience; Three series of porphyrins containing a Zn(II) central metal ion and zero, one or two phosphoryl groups at the meso-positions of the macrocycle were characterized as to their electrochemical, spectroscopic and structural properties in non-aqueous media. The investigated compounds are represented as 5,15-bis(4'-R-phenyl)porphyrinatozinc, 10-(diethoxyphosphoryl)-5,15-bis(4'-R-phenyl)porphyrinatozinc and 5,15-bis(diethoxyphosphoryl)-10,20-bis(4'-R-phenyl)porphyrinatozinc, where R = OMe, Me, H or CN. Linear-free energy relationships are observed between the measured redox potentials at room temperature and the electronic nature of the substituents at the 5 and 15 meso-ph…

010405 organic chemistryChemistryInorganic chemistrychemistry.chemical_elementZinc010402 general chemistryElectrochemistry01 natural sciences0104 chemical sciencesInorganic ChemistryMetal[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistryvisual_artvisual_art.visual_art_medium[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical Chemistry
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Localization of alkali metal ions in sodium-promoted palladium catalysts as studied by low energy ion scattering and transmission electron microscopy

1996

Three series of palladium-based catalysts have been studied by Low Energy Ion Scattering (LEIS) and Transmission Electron Microscopy (TEM). The first series is comprised of Na-Pd/SiO{sub 2} catalysts, obtained by addition of palladium to a silica support and by further addition of sodium ions with a Na/Pd atomic ratio (R) equal to 0,6.4 and 25.6. The second series consists of palladium catalysts supported on natural pumice, in which, due to a different loading of supported palladium, R{prime}, the (Na+K)/Pd atomic ratio, is equal to 17.0 and 39.4. The third series is represented by two palladium-based catalysts supported on {open_quotes}model pumices,{close_quotes} synthetic silico-aluminat…

010405 organic chemistryChemistryInorganic chemistrychemistry.chemical_element[CHIM.CATA]Chemical Sciences/Catalysis010402 general chemistryAlkali metal01 natural sciencesCatalysis0104 chemical sciencesCatalysisIonMetalTransition metalLow-energy ion scatteringvisual_artvisual_art.visual_art_mediumAtomic ratioPhysical and Theoretical ChemistryPalladium
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Intermolecular and Intramolecular Transamidation Reactions

2006

The amide functional group is resonance stabilised and direct reaction with amines is known to be difficult. Facile amide exchange reactions would enable the synthesis of important new amide based molecules, therefore transamidation reactions represent an important step in this direction. In order to ensure a transamidation reaction takes place, special requirements and conditions are required. According to the different structural characteristics of the carbox-amide group and types of activation, the most relevant examples of this reaction will be reviewed.

010405 organic chemistryChemistryIntermolecular forceGeneral MedicinePhotochemistry010402 general chemistryResonance (chemistry)01 natural sciences0104 chemical scienceschemistry.chemical_compoundComputational chemistryIntramolecular forceAmideFunctional groupPolymer chemistryDirect reactionPhysical and Theoretical ChemistryProgress in Reaction Kinetics and Mechanism
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