Search results for "RICE"
showing 10 items of 2331 documents
DNA replication arrest in response to genotoxic stress provokes early activation of stress-activated protein kinases (SAPK/JNK).
2009
Abstract The impact of DNA damage-induced replication blockage for early activation of stress kinases [stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK)] is largely unknown. Here, we show that induction of dual phosphorylation of SAPK/JNK by the DNA polymerase inhibitor aphidicolin was not ameliorated by additional exposure to ultraviolet (UV) light, indicating that overlapping mechanisms participate in signaling to SAPK/JNK triggered by both agents. UV-induced DNA replication blockage, cyclobutane pyrimidine dimer formation and DNA strand break induction coincided with SAPK/JNK phosphorylation at early (≤ 30 min) but not late (≥ 2 h) time points after exposure. Genotoxin…
Haptoglobin interacts with apolipoprotein E and beta-amyloid and influences their crosstalk.
2014
Beta-amyloid accumulation in brain is a driving force for Alzheimer's disease pathogenesis. Apolipoprotein E (ApoE) represents a critical player in beta-amyloid homeostasis, but its role in disease progression is controversial. We previously reported that the acute-phase protein haptoglobin binds ApoE and impairs its function in cholesterol homeostasis. The major aims of this study were to characterize the binding of haptoglobin to beta-amyloid, and to evaluate whether haptoglobin affects ApoE binding to beta-amyloid. Haptoglobin is here reported to form a complex with beta-amyloid as shown by immunoblotting experiments with purified proteins, or by its immunoprecipitation in brain tissues …
Simple connections between generalized hypergeometric series and dilogarithms
1997
AbstractConnections between generalized hypergeometric series and dilogarithms are investigated. Some simple relations of an Appell's function and dilogarithms are found.
Pricing of electricity futures based on locational price differences : The case of Finland
2018
We find that the pricing of Finnish electricity market futures has been inefficient during the latest 10 years, when the trading volumes of Electricity Price Area Differentials (EPADs) have more than doubled. Even though the calculated futures premium on EPADs is related to some risk measures and the variables capturing the demand and supply conditions in the spot electricity markets, there has been a significant positive excess futures premium in the Finnish market, and financial market participants should have been able to utilize this also in economic terms. This finding is new and relevant for the participants of the Nordic electricity markets also in the future, because both the specul…
Branch-Price-and-Cut for the Soft-Clustered Capacitated Arc-Routing Problem
2021
The soft-clustered capacitated arc-routing problem (SoftCluCARP) is a variant of the classical capacitated arc-routing problem. The only additional constraint is that the set of required edges, that is, the streets to be serviced, is partitioned into clusters, and feasible routes must respect the soft-cluster constraint, that is, all required edges of the same cluster must be served by the same vehicle. In this article, we design an effective branch-price-and-cut algorithm for the exact solution of the SoftCluCARP. Its new components are a metaheuristic and branch-and-cut-based solvers for the solution of the column-generation subproblem, which is a profitable rural clustered postman tour …
Archaeological survey projects in Sicily: issues and best practices from eighties to present time
2017
A partire dagli anni '80 del secolo scorso sono state effettuate numerose indagini archeologiche in Sicilia, in zone dell'isola molto diverse: approcci metodologici, contesti geografici e cronologici, ed infine lo stato dell'edizione, non sempre sono confrontabili tra loro da molti punti di vista Visualizza. Lo scopo di questo lavoro è sia di esaminare questi progetti, prestando attenzione agli aspetti metodologici e di possibili distorsioni interpretative, sia di elaborare buone pratiche utili per nuovi progetti. Since the 80s of the last century several archaeological surveys were carried out in Sicily, in very different areas of the island: methodological approaches, geographical and chr…
Archaeometric characterization of late Archaic ceramic from Erice (Sicily) aimed to provenance determination
2019
A set of 20 ceramic samples was autoptically selected from the numerous findings recovered from the stratigraphic excavations of the late Archaic city walls of Erice (western Sicily), in order to be analyzed with archaeometric techniques for provenance determination. The excavations were recently carried out as part of a research project funded by the Freie Universiat Berlin and the Fritz Thyssen Foundation. Specifically, the ceramic material consists of tableware with a painted geometric decoration of presumed local/regional production, as well as apparently imported black-glazed pottery. Both the categories can be traced back to a chronological period between the second half/last quarter …
Il modello virtuale dell'anfiteatro
2016
Studio ricostruttivo dell'anfiteatro romano di Rudiae (Lecce)
Il progetto ‘Hierapolis Virtuale’: analisi integrate per lo studio dell’architettura ierapolitana. L’esempio del teatro extraurbano
2016
Nell’ambito delle attività della Missione Archeologica Italiana a Hierapolis di Frigia è stato sviluppato un ambizioso progetto di restituzione dell’immagine della città ellenistico-romana e bizantina denominato ‘Hierapolis Virtuale’, finalizzato al restauro virtuale e alla ricostruzione tridimensionale dei complessi monumentali oggetto di indagine da parte dei vari team di ricerca. Il progetto nasce nel 2007 e prende spunto da alcuni lavori eseguiti dal Laboratorio di Informatica Applicata ai Beni Archeologici e Monumentali dell’IBAM-CNR di Lecce negli anni precedenti, quali lo studio ricostruttivo del Ninfeo dei Tritoni, realizzato nel 2004 (rielaborato ed aggiornato nel 2010) e le scansi…
“Sources of Research” for the Virtual Reconstruction of Ancient Monuments: The Case of Architectural Models
2023
The use of architectural scale models, also known by the French word maquette or the Italian names plastico or modello, is an ancient practice, which prob-ably began when architecture emerged from its purely practical and utilitarian phase to become a formal category of knowledge with specifically sought-after and deliber-ately selected characteristics, linked to the increased dimensions and the enrichment of forms [1]. The model constitutes a representation, generally on a smaller scale and made of different materials but similar in effect, of a work to be created. Models are made of various materials, in accordance with the tastes of Scholars and with need, such as wood, wax, terracotta, …