Search results for "RICE"

Possible relationship between micronucleated and binucleated cells induced by cisplatin in cultured CHO cells

1993

Abstract Chinese hamster ovary (CHO) cells were treated with a single dose (10 μg/ml) of cis-diammino-dichloroplatinum (II) (cisplatin) for 1 h and the effect of the drug on the kinetics of proliferation of the cultures was studied. It was found that the drug produces a delay in the proliferation rates of the treated cultures. The induction of micronuclei and binucleated cells (BC) at different times after treatment have also been studied, and the ability of these cells to undergo DNA synthesis (measured as the ability to incorporate [3H]thymidine) is shown. It was found that cisplatin induced a particular type of BC that contains one or more micronuclei rather than a pure population of BC.…

Genotoxicity of citrus wastewater in prokaryotic and eukaryotic cells and efficiency of heterogeneous photocatalysis by TiO(2).

2012

Abstract The presence of (±)α-pinene, (+)β-pinene, (+)3-carene, and R-(+)limonene terpenes in wastewater of a citrus transformation factory was detected and analyzed, in a previous study, by using Solid Phase Micro-extraction (SPME) followed by GC analyses. Purpose of that research was to compare the genotoxic responses of mixtures of terpenes with the genotoxicity of the individual compounds, and the biological effects of actual wastewater. Genotoxicity was evaluated in the Salmonella reversion assay (Ames test) and in V79 cells by Comet assay. Ames tests indicated that the four single terpenes did not induce an increase of revertants frequency. On the contrary, the mixtures of terpenes ca…

Palermo: ricerca scientifica e sostenibilità per la social innovation

2016

Nonostante le mancanze strutturali e i risultati negativi osservati attraverso l’analisi degli indicatori statistici sulla smartness, specialmente nel confronto con i risultati alla scala nazionale, la Città Metropolitana di Palermo sembra essere interessata da una sempre crescente consapevolezza sul tema della Smart City. Anche se attualmente manca una cornice governativa che coordini il mosaico di iniziative portate avanti in vari campi della smartness, il bisogno e la volontà di andare verso lo sviluppo di una città più intelligente stanno attivando e richiamando all’azione sia le istituzioni - come l’Università, gli organismi di governo locale e gli istituti di ricerca - che le associaz…

Combining workload balance and patient priority maximisation in operating room planning through hierarchical multi-objective optimisation

2022

Abstract Previous analysis suggested the opportunity to consider the preferences of different stakeholders (hospital, patients, doctors and nurses) through the adoption of both patient priority maximisation and workload balance as performance criteria. The aim of this paper is to develop an effective and efficient solution approach for the operating room planning and scheduling capable to take into account the patient priority maximisation and workload balance criteria at the same time. This work is inspired by the need of a deeper understanding of the quality of the solutions obtained when a combination of the two criteria leads the OR planning decisions. Starting from a hierarchical multi…

Producer's spatial equilibrium with a fuzzy constraint

1980

The classical theory of the producer’s equilibrium rests on two sets of particularly restrictive hypotheses. First it is implicitely assumed that all inputs and outputs are located in a single place where the producer is also implanted and where the production is carried out. Next it is assumed that the producer follows a precise behaviour pattern, by this we mean that the producer has complete information concerning the conditions of hisproductive activity and he has perfect command over both the set of inputs and the set of outputs; he realises the maximum profit allowed by the technological constraint which limits his possible actions and by the given price system. The aim of this study …

«Student Voice» per la valorizzazione delle risorse personali

2017

Negli ultimi dieci anni, un nuovo movimento di opinione in campo educativo si è diffuso in Italia per stimolare i responsabili delle politiche educative e gli insegnanti di ogni ordine e grado dell’istruzione ad ascoltare attentamente le voci, nonché i bisogni e gli interessi di tutti gli studenti. Si tratta del movimento «Student Voice», nato negli anni Novanta nel Regno Unito e diffusosi in alcuni Paesi di area anglofona (USA, Canada, Australia). Questo movimento sostiene la partecipazione attiva e responsabile di tutti gli studenti ai processi formativi che si attivano nelle scuole e nelle università: nello specifico, questa partecipazione si esplica nella didattica in aula, nelle ricerc…

Quale ricerca è utile per la clinica? Introduzione al dibattito.

2011

Acidic cytosolic proteins are preferentially imported into rat liver lysosomes.

1998

Previous studies have reported that lysosomes isolated from human diploid fibroblasts and from rat liver can selectively import and degrade specific proteins. We have now reinvestigated this selectivity using an in vitro assay with rat liver lysosomes and an extract of cytosolic proteins prepared from cultured cells labeled to equilibriums with [35S-]methionine. Analysis by two-dimensional gel electrophoresis and autoradiography of the cytosolic proteins bound to the lysosomal membrane and imported into the lysosomes shows that when all cytosolic proteins are simultaneously present in the in vitro assay the lysosomal uptake also occurs in a specific manner. These findings suggest that isola…

Comprehensive analysis of forty yeast microarray datasets reveals a novel subset of genes (APha-RiB) consistently negatively associated with ribosome…

2014

Background The scale and complexity of genomic data lend themselves to analysis using sophisticated mathematical techniques to yield information that can generate new hypotheses and so guide further experimental investigations. An ensemble clustering method has the ability to perform consensus clustering over the same set of genes from different microarray datasets by combining results from different clustering methods into a single consensus result. Results In this paper we have performed comprehensive analysis of forty yeast microarray datasets. One recently described Bi-CoPaM method can analyse expressions of the same set of genes from various microarray datasets while using different cl…

Millstone coastal quarries of the Mediterranean: A new class of sea level indicator

2014

The coasts of Italy still preserve several remnants of coastal quarries built in antiquity, that now provide insights into the intervening sea-level changes occurred during the last millennia. In this paper, we show and discuss a new class of sea level indicator consisting of millstones carved along the rocky coast of southern Italy since 2500 BP, that are currently submerged. They were extracted from beachrocks, sandstones or similar sedimentary rocks, easier for carving by ancient carving tools. Our study focuses on 10 coastal sites located at Capo d'Orlando, Avola, and Letojanni, in Sicily; Soverato, Tropea, and Capo dell'Armi, in Calabria; Castellabate, Palinuro, and Scario, in Campania…