Search results for "RICH"

showing 10 items of 3360 documents

CCDC 1438418: Experimental Crystal Structure Determination

2016

Related Article: Vincent Rampazzi, Julien Roger, Régine Amardeil, Marie-José Penouilh, Philippe Richard, Paul Fleurat-Lessard, and Jean-Cyrille Hierso|2016|Inorg.Chem.|55|10907|doi:10.1021/acs.inorgchem.6b01318

(mu-11'22'-tetrakis(diphenylphosphino)-44'-di-t-butylferrocene)-trichloro-tri-gold dichloromethane solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

2017

A large amount of data is currently available on the adaptive mechanisms of polar bony fish hemoglobins, but structural information on those of cartilaginous species is scarce. This study presents the first characterisation of the hemoglobin system of one of the longest-living vertebrate species (392 +/- 120 years), the Arctic shark Somniosus microcephalus. Three major hemoglobins are found in its red blood cells and are made of two copies of the same a globin combined with two copies of three very similar beta subunits. The three hemoglobins show very similar oxygenation and carbonylation properties, which are unaffected by urea, a very important compound in marine elasmobranch physiology.…

---0301 basic medicinegenetic structuresProtein ConformationGreenlandlcsh:MedicineRESONANCE RAMAN-SPECTRAHETERODONTUS-PORTUSJACKSONISpectrum Analysis RamanBiochemistrychemistry.chemical_compoundHemoglobinsProtein structureAMINO-ACID SEQUENCEAnimal CellsSequence Analysis ProteinRed Blood CellsUreaNOTOTHENIOID FISHESPost-Translational Modificationlcsh:ScienceHemeChondrichthyesMultidisciplinarybiologyChemistryOrganic CompoundsChemical ReactionsVertebrateEukaryotaMOLECULAR ADAPTATIONSMicrocephalusGlobinsChemistryBiochemistryOptical EquipmentVertebratesPhysical SciencesEngineering and TechnologyCellular TypesResearch ArticleEnvironmental MonitoringProtein BindingQUATERNARY STRUCTURESAllosteric regulationEquipmentSTRETCHING FREQUENCIESHeme03 medical and health sciencesOXYGEN-BINDINGbiology.animalAnimals14. Life underwaterGlobinHemoglobinPhotolysisBlood Cells030102 biochemistry & molecular biologyLaserslcsh:ROrganic ChemistryOrganismsChemical CompoundsBiology and Life SciencesProteinsxxxCell Biologybiology.organism_classificationCARTILAGINOUS FISHOxygen030104 developmental biologySomniosusFishSharkslcsh:QHemoglobinProtein MultimerizationELASMOBRANCH HEMOGLOBINElasmobranchiiPLoS ONE
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Prevalence and characteristics of antidepressant drug prescriptions in older Italian patients.

2012

ABSTRACTBackground: During last few decades, the proportion of elderly persons prescribed with antidepressants for the treatment of depression and anxiety has increased. The aim of this study was to evaluate prevalence of antidepressant prescription and related factors in elderly in-patients, as well as the consistency between prescription of antidepressants and specific diagnoses requiring these medications.Methods: Thirty-four internal medicine and four geriatric wards in Italy participated in the Registro Politerapie SIMI–REPOSI study during 2008. In all, 1,155 in-patients, 65 years or older, were enrolled. Prevalence of the use of antidepressants was calculated at both admission and dis…

---DrugMalemedicine.medical_specialtyMultivariate analysisSettore MED/09 - Medicina Internaantidepressants; prescription; elderly; hospitalization; dementiamedia_common.quotation_subjectLogistic regressionelderlySex FactorsInternal medicinemedicinePrevalenceantidepressant drugsDementiaHumansMedical prescriptionPractice Patterns Physicians'PsychiatryDepression (differential diagnoses)media_commonAgedprescriptionantidepressantbusiness.industryDepressionAge Factorsmedicine.diseaseSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheAntidepressive AgentsPsychiatry and Mental healthClinical PsychologyLogistic Models---; elderly; antidepressant drugs; PrevalenceItalyAnxietyAntidepressantDementiaFemaleGeriatrics and Gerontologymedicine.symptombusinessGerontologyhospitalizationInternational psychogeriatrics
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Association between clusters of diseases and polypharmacy in hospitalized elderly patients: results from the REPOSI study.

2011

BACKGROUND: Although the association between multimorbidity and polypharmacy has been clearly documented, no study has analyzed whether or not specific combinations of diseases influence the prescription of polypharmacy in older persons. We assessed which clusters of diseases are associated with polypharmacy in acute-care elderly in-patients. METHODS: This cross-sectional study was held in 38 Italian internal medicine and geriatric wards participating in the Registro Politerapie SIMI (REPOSI) study during 2008. The study sample included 1155 in-patients aged 65 years or older. Clusters of diseases, defined as two or more co-occurring specific chronic diseases, were identified using the odds…

---Lung DiseasesMaleSettore MED/09 - Medicina InternaCross-sectional studyGastrointestinal DiseasesComorbidityRisk FactorsNeoplasmsPrevalenceCluster AnalysisHospitalized elderlyclustersGeriatricsAged 80 and overCOPDREPOSISettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHospitalization---; clusters; polypharmacy; REPOSI; elderlyCardiovascular DiseasesFemalemedicine.medical_specialtyEndocrine System DiseaseselderlyCluster of diseasesInternal medicineDiabetes mellitusmedicineDiabetes MellitusInternal MedicineMultimorbidityHumansCluster of diseases; Hospitalized elderly; PolypharmacyAgedPolypharmacybusiness.industryPolypharmacy Cluster of diseases Hospitalized elderlyOdds ratiomedicine.diseaseComorbidityCross-Sectional StudiesLogistic ModelsGeriatricsPhysical therapyPolypharmacyDementiaMorbiditybusinessEuropean journal of internal medicine
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Performance of PSI, CURB-65, and SCAP scores in predicting the outcome of patients with community-acquired and healthcare-associated pneumonia

2011

The objective was to compare three score systems, pneumonia severity index (PSI), the Confusion-Urea-Respiratory Rate-Blood pressure-65 (CURB-65), and severe community-acquired pneumonia (SCAP), for prediction of the outcomes in a cohort of patients with community-acquired (CAP) and healthcare-associated pneumonia (HCAP). Large multi-center, prospective, observational study was conducted in 55 hospitals. HCAP patients were included in the high classes of CURB-65, PSI and SCAP scores have a mortality rate higher than that of CAP patients. HCAP patients included in the low class of the three severity rules have a significantly higher incidence of adverse events, including development of septi…

---medicine.medical_specialtySettore MED/09 - Medicina Internacommunity-acquired pneumoniaPneumonia severity indexBlood PressureSettore MED/10 - Malattie Dell'Apparato RespiratorioCommunity-acquired pneumonia Healthcare-associated pneumonia PSI CURB 65Severity of Illness IndexCommunity-acquired pneumoniaRespiratory RatePredictive Value of TestsInternal medicineCURB 65Severity of illnessInternal MedicinePneumonia BacterialMedicineHumansUreaPSIProspective StudiesIntensive care medicineProspective cohort studyConfusion---; community-acquired pneumonia; Healthcare-associated pneumonia; PSI; CURB 65Cross Infectioncommunity-acquired pneumonia; psi; healthcare-associated pneumonia; curb 65business.industryMortality ratemedicine.diseasePrognosisCURB-65Settore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHealthcare-associated pneumoniaCommunity-Acquired InfectionsPneumoniaCohortEmergency Medicinebusiness
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A singular (p,q)-equation with convection and a locally defined perturbation

2021

Abstract We consider a parametric Dirichlet problem driven by the ( p , q ) -Laplacian and a reaction which is gradient dependent (convection) and the competing effects of two more terms, one a parametric singular term and a locally defined perturbation. We show that for all small values of the parameter the problem has a positive smooth solution.

010101 applied mathematicsDirichlet problemConvectionApplied Mathematics010102 general mathematicsMathematical analysisSingular termPerturbation (astronomy)0101 mathematics01 natural sciencesLaplace operatorMathematicsParametric statisticsApplied Mathematics Letters
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Inverse problems for $p$-Laplace type equations under monotonicity assumptions

2016

We consider inverse problems for $p$-Laplace type equations under monotonicity assumptions. In two dimensions, we show that any two conductivities satisfying $\sigma_1 \geq \sigma_2$ and having the same nonlinear Dirichlet-to-Neumann map must be identical. The proof is based on a monotonicity inequality and the unique continuation principle for $p$-Laplace type equations. In higher dimensions, where unique continuation is not known, we obtain a similar result for conductivities close to constant.

010101 applied mathematicsunique continuation principleMathematics - Analysis of PDEsinverse problems010102 general mathematicsFOS: MathematicsDirichlet-to-Neumann map35J92 35R300101 mathematics01 natural sciencesp-Laplace equationinversio-ongelmatAnalysis of PDEs (math.AP)
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Enhanced loss model algorithm for interior permanent magnet synchronous machines

2017

This paper presents an experimental study on the impact of the parameter variations over the performances of a LMA (Loss Model Algorithm) designed for an IPMSM (Interior Permanent Magnet Synchronous Machine). In a previous work, the characterization was carried out by assessing, for several working conditions, the motor parameters that influence the motor efficiency. The proposed enhanced loss model algorithm is implemented in a rapid prototyping system and its performances, in term of efficiency, are compared with other control systems, obtaining promising results.

010302 applied physicsRapid prototypingInterior permanent magnet synchronous motorComputer science020208 electrical & electronic engineeringWork (physics)02 engineering and technologySettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettrici01 natural sciencesDC motorTerm (time)Settore ING-IND/31 - Elettrotecnicaspeed control drive systemsMagnetControl system0103 physical sciences0202 electrical engineering electronic engineering information engineeringTorquepower loss minimizationSettore ING-INF/07 - Misure Elettriche E ElettronicheAlgorithmPermanent magnet synchronous machine2017 AEIT International Annual Conference
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New crystal structures of fluorinated α-aminophosphonic acid analogues of phenylglycine

2020

The four novel phosphonic acid analogues of phenylglycine with various substituents in phenyl ring (mostly fluorine atoms) have been synthesized by using procedure of amidoalkylation of phosphorus trichloride with aromatic aldehydes and acetamide. The NMR, ESI-MS spectroscopy, and single-crystal X-Ray diffraction methods were used to characterize unusual structures: the amino-(4-trifluoromethylbenzyl)-(1), amino-(3,4-difluorobenzyl)-(2), amino-(2,4,6-trifluorobenzyl)-(3), and amino-(2-fluoro-4-hydroxybenzyl)-(4) phosphonic acids. Since the α-aminophosphonates have a potential for biological activity and could be used as building blocks in medicinal chemistry, it is important to know their d…

010405 organic chemistryCrystal and molecular structureschemistry.chemical_elementBiological activityCrystal structure010402 general chemistryCondensed Matter PhysicsRing (chemistry)01 natural sciencesMedicinal chemistryNMRESI-MS spectra0104 chemical sciencesTurn (biochemistry)chemistry.chemical_compoundchemistryFluorinated α-aminophosphonic acidFluorinePhosphorus trichloridePhysical and Theoretical ChemistrySpectroscopyAcetamideStructural Chemistry
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The effect of bone marrow-derived stem cells associated with platelet-rich plasma on the osseointegration of immediately placed implants

2020

Background Stem cells associated with growth factors have been shown to improve bone healing and the osseointegration of dental implants. A Brazilian miniature pig model was used to evaluate the effect of autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) associated with platelet-rich plasma (PRP) on the osseointegration of immediately placed dental implants. Material and methods A total of four male adult miniature pigs were used in this study. BM-MSCs from each pig were isolated from the iliac crest and expanded in vitro. The undifferentiated BM-MSCs were mixed with autologous PRP and implanted in the post-extraction sockets at the experimental sites before implant placement …

010407 polymersMiniature pigbiologyBone densitybusiness.industryResearchDentistry02 engineering and technologyBone healing021001 nanoscience & nanotechnologybiology.organism_classification01 natural sciencesIliac crestOsseointegration0104 chemical sciencesmedicine.anatomical_structurePlatelet-rich plasmaBiomaterials and Bioengineering in DentistryMedicineImplantBone marrow0210 nano-technologybusinessGeneral DentistryUNESCO:CIENCIAS MÉDICASJournal of Clinical and Experimental Dentistry
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