Search results for "RICH"
showing 10 items of 3360 documents
A Cross-Sectional Study on the Prevalence and Incidence of Pressure Ulcers in an Italian University Hospital-Umbria Region
2020
Objective: The aim of the present study was to assess the prevalence and incidence of pressure ulcers (PUs) in patients hospitalized in a University Hospital in central Italy. Methods: We carried out a prevalence and incidence study on PUs and an additional prevalence estimate of PUs was also produced ten days after the first assessment. All data were explored by descriptive statistics, the Chi-square test and a multivariate analysis. Results: The prevalence of pressure ulcers was of 6,5%, while it increased to 9,9% at the second assessment ten days after the first measurement. Prevalence was statistically significant and increased with the age of inpatients (p=0,004) and was correlated to …
Fenomenologie inquisitorie o guarentigie costituzionali nelle dinamiche dei poteri ex art. 409, 4° comma, c.p.p. del g.i.p. sull'inazione del p.m.?
2022
Le sezioni unite hanno riconosciuto in capo al g.i.p. il potere di ordinare al p.m. di procedere, quale atto di indagine suppletivo disposto a norma dell'art. 409, 4° comma, c.p.p., all'interrogatorio dell'indagato, anche per un reato diverso da quello per il quale il magistrato requirente aveva richiesto l'archiviazione, essendo dovuta, in tal caso, solo la previa iscrizione nel registro ex art. 335 c.p.p.
Il contributo delle indagini colorimetriche per la conservazione programmata dei mosaici della villa romana del casale di Piazza Armerina (Enna)
2008
I mosaici della Villa Romana del Casale di Piazza Armerina: il contributo delle indagini colorimetriche per la stesura del protocollo di intervento
2007
2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors.
2019
Abstract A class of 36 new 2-(6-phenylimidazo[2,-1-b][1,3,4]thiadiazol-2-yl)-1H-indoles was efficiently synthesized and evaluated for their anti-biofilm properties against the Gram-positive bacterial reference strains Staphylococcus aureus ATCC 25923, S. aureus ATCC 6538 and Staphylococcus epidermidis ATCC 12228, and the Gram-negative strains Pseudomonas aeruginosa ATCC 15442 and Escherichia coli ATCC 25922. Many of these new compounds, were able to inhibit biofilm formation of the tested staphylococcal strains showing BIC50 lower than 10 μg/ml. In particular, derivatives 9c and 9h showed remarkable anti-biofilm activity against S. aureus ATCC 25923 with BIC50 values of 0.5 and 0.8 μg/ml, r…
Diacylglycerols containing Omega 3 and Omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation.
2003
We elucidated the effects of different diacylglycerols (DAGs), i.e. 1-stearoyl-2-arachidonoyl-sn-glycerol (SAG), 1-stearoyl-2-docosahexaenoyl-sn-glycerol (SDG), and 1-stearoyl-2-eicosapentaenoyl-sn-glycerol (SEG), on [3H]PDBu binding to RasGRP. The competition studies with these DAGs on [3H]PDBu binding to RasGRP revealed different Ki values for these DAG molecular species. Furthermore, we transfected human Jurkat T cells by a plasmid containing RasGRP and assessed the implication of endogenous DAGs on activation of MAP kinases ERK1/ERK2, induced by phorbol-12-myristate-13-acetate (PMA). In control cells, GF109203X, a protein kinase C inhibitor, inhibited ERK1/ERK2 activation. However, this…
Infection pulmonaire invasive à Trichoderma longibrachiatum, à propos d’un cas
2015
Introduction : Trichoderma longibrachiatum est un champignon filamenteux appartenant à la famille des hyalohyphomycètes, rarement isolé lors d’infections fongiques invasives chez l’Homme mais quelques cas ont déjà été décrits chez des sujets immunodéprimés. Observation : Un homme de 69 ans a développé un syndrome fébrile une semaine après la fin d’une chimiothérapie pour le traitement d’une leucémie aiguë myéloïde alors qu’il était en aplasie profonde (GB Aspergillus Galactomannan test), un scanner thoracique est réalisé. L’aspect scannographique (signe du halo) était évocateur d’une aspergillose pulmonaire invasive (API), motivant la réalisation d’un lavage broncho-alvéolaire (LBA). Le LBA…
Efficacy of a functional therapy program for depression and c-reactive protein: A pilot study
2021
Objective: Affecting more than 264 million people, depression is a systemic and multifactorial disorder that represents one of the leading causes of illness and disability worldwide. Several studies showed an inflammatory response in depressed patients, including the involvement of both chronic low-grade inflammatory response and activation of cell-mediated immunity. The present study aimed to verify the efficacy of a structured functional therapy program for patients with depressed mood, and to determine whether this program can significantly reduce levels of C-reactive protein. Method: 28 outpatients with depressed mood received 20 individual sessions of Functional therapy. Data about soc…
Innesto di catene polimeriche sulla superficie di nanotube di carbonio mediante reazione di accoppiamento radicalico
2015
La modifica di nanotubi di carbonio (CNT) attraverso innesto (grafting) di catene polimeriche sulla loro superficie è un metodo efficace per promuovere la dispersione di queste cariche a livello nanometrico in una matrice polimerica. La funzionalizzazione covalente di CNT con catene polimeriche viene generalmente ottenuta sia attraverso crescita controllata di polimeri a partire dalle pareti della nanocarica mediante metodi "grafting from" sia attraverso metodi di "grafting to" che si basano sulla reazione di condensazione tra polimeri preformati e CNT opportunamente modificati. In questo lavoro viene proposto un nuovo approccio di tipo "grafting to" per innestare catene polimeriche su CNT …
A novel target of lithium therapy.
2000
Phosphatases converting 3'-phosphoadenosine 5'-phosphate (PAP) into adenosine 5'-phosphate are of fundamental importance in living cells as the accumulation of PAP is toxic to several cellular systems. These enzymes are lithium-sensitive and we have characterized a human PAP phosphatase as a potential target of lithium therapy. A cDNA encoding a human enzyme was identified by data base screening, expressed in Escherichia coli and the 33 kDa protein purified to homogeneity. The enzyme exhibits high affinity for PAP (K(m)1 microM) and is sensitive to subtherapeutic concentrations of lithium (IC(50)=0.3 mM). The human enzyme also hydrolyzes inositol-1, 4-bisphosphate with high affinity (K(m)=0…