Search results for "RICH"
showing 10 items of 3360 documents
The Importance of the Nurse’s Role in the Management of Complex Diabetic Outpatients: It is the Time to Manage Patient’s Multidimensions
2018
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Coexpression of inducible NO synthase and soluble guanylyl cyclase in colonic enterocytes: a pathophysiologic signaling pathway for the initiation of…
1998
Infectious diarrhea is often caused by the exotoxins of gram-negative bacteria such as Escherichia coli. However, these organisms also contain lipopolysaccharide (LPS) endotoxin. LPS induces nitric oxide synthase II (NOS II, inducible NOS) in various types of cells. We now demonstrate by RNase protection analysis, Western blot, and immunohistochemistry that the expression of NOS II mRNA and protein is markedly induced in colonic enterocytes of mice that ingest LPS with their drinking water. Using the same techniques, significant levels of soluble guanylyl cyclase (GC-S), the effector enzyme of NO, were found constitutively expressed in the mucosa. This creates a pathophysiologic autocrine p…
Homotypic Protection Against Rotavirus-Induced Diarrhea in Infant Mice Breast-Fed by Dams Immunized with the Recombinant VP8* Subunit of the VP4 Caps…
2000
The outer capsid proteins VP4 and VP7 induce neutralizing antibody against rotavirus. We have investigated in a mouse model the protection mediated by immunization with VP8*, the amino-terminal tryptic fragment of VP4. BALB/c female mice immunized with simian rotavirus SA11 VP6 and VP8* proteins expressed in Escherichia coli were mated with seronegative males. Litters were orally challenged with the SA11 strain (P5B[2], G3) or with the murine rotavirus strain EDIM (P10[16], G3) to verify the degree of protection against diarrhea induced in the newborns. Only those pups born to dams immunized with VP8* did not develop diarrhea after having been orally challenged with the SA11 strain. Pups bo…
Expression of P, S, and F1C adhesins by cytotoxic necrotizing factor1-producing Escherichia coli from septicemic and diarrheic pigs
1997
Nineteen papC-positive cytotoxic necrotizing factor 1 (CNF1)-producing Escherichia coli isolates from pigs with septicemia or diarrhea were tested for the presence of pap-, sfa-, and afa-related sequences encoding P/Prs, S/F1C, and Dr/AFA adhesins respectively. Production of adhesins by isolates was tested by mannose-resistant hemagglutination (MRHA), sialidase treatment of erythrocytes and particle agglutination tests. Production of P, S, and F1C fimbriae by isolates was also examined by immunofluorescence. All isolates were pap+ by PCR. Eighteen isolates (95%) were MRHA for ovine and human A erythrocytes and exhibited GalNac-GalNac receptor specificity associated with class III P(Prs) adh…
The sensor kinase DcuS of Escherichia coli: two stimulus input sites and a merged signal pathway in the DctA/DcuS sensor unit
2012
Abstract The membrane-integral sensor kinase DcuS of Escherichia coli consists of a periplasmically located sensory PASP domain, transmembrane helices TM1 and TM2, a cytoplasmic PASC domain and the kinase domain. Stimulus (C4-dicarboxylate) binding at PASP is required to stimulate phosphorylation of the kinase domain, resulting in phosphoryl transfer to the response regulator DcuR. PASC functions as a signaling device or a relay in signal transfer from TM2 to the kinase. Phosphorylated DcuR induces the expression of the target genes. Sensing by DcuS requires the presence of the C4-dicarboxylate transporter DctA during aerobic growth. DctA forms a sensor unit with DcuS, and a short C-termina…
Brief an Garlieb H. Merkel
1798
Ms. 930a, Nr. 12, Bl. 31r-34v Johannes Daniel Falk. Brief an Garlieb H. Merkel, Weimar, den 3. December 179[8?] Autora rokraksts / Autograph, vācu val. / Deutsch [8] lpp. / S. Attēlu numuri / Bildnummern: 930a-012-1, 930a-012-2-3, 930a-012-4-5, 930a-012-6-7, 930a-012-8 Im vorliegenden Brief vermischen sich private und berufliche Angelegenheiten sowie Klatsch miteinander. Nachdem Falk seine lange Antwortzeit zunächst damit begründet, dass er Merkels aktuelle Adresse nicht kenne, bringt er Neuigkeiten von der Krankheit einer nicht näher benannten Kammerrätin und nimmt an deren Leiden rege Anteil. Direkt im Anschluss präsentiert Falk den Stand seiner Verhandlungen mit Verlegern. Auch wenn Falk…
Circolazione e sviluppo di un modello metodologico. La critica testuale delle fonti giuridiche romane fra Otto Gradenwitz e Salvatore Riccobono
2018
La ricerca delle interpolazioni, cominciata con la Scula culta, viene ripresa in Germania alla fine del XIX secolo. Fra quanti misero a punto un metodo storico-critico per lo studio delle fonti giuridiche romane va menzionato anche Gradenwitz, che – insieme ad altri studiosi tedeschi – sarebbe stato uno dei maestri di Riccobono. La prima produzione scientifica di Riccobono, che si riconosce nel nuovo indirizzo storico-critico affermatosi in Germania, si avvale dei metodi appresi dai maestri tedeschi. Lungo questo solco, tuttavia, comincia l’elaborazione di un metodo più raffinato, che distingue fra interpolazioni formali e interpolazioni sostanziali e recupera gradualmente altri strumenti d…
Patterns and dynamics of neutral lipid fatty acids in ants – implications for ecological studies
2017
Background Trophic interactions are a fundamental aspect of ecosystem functioning, but often difficult to observe directly. Several indirect techniques, such as fatty acid analysis, were developed to assess these interactions. Fatty acid profiles may indicate dietary differences, while individual fatty acids can be used as biomarkers. Ants are among the most important terrestrial animal groups, but little is known about their lipid metabolism, and no study so far used fatty acids to study their trophic ecology. We set up a feeding experiment with high- and low-fat food to elucidate patterns and dynamics of neutral lipid fatty acids (NLFAs) assimilation in ants. We asked whether dietary fatt…
Positive solutions for a discrete two point nonlinear boundary value problem with p-Laplacian
2017
Abstract In the framework of variational methods, we use a two non-zero critical points theorem to obtain the existence of two positive solutions to Dirichlet boundary value problems for difference equations involving the discrete p -Laplacian operator.
Extremal solutions and strong relaxation for nonlinear multivalued systems with maximal monotone terms
2018
Abstract We consider differential systems in R N driven by a nonlinear nonhomogeneous second order differential operator, a maximal monotone term and a multivalued perturbation F ( t , u , u ′ ) . For periodic systems we prove the existence of extremal trajectories, that is solutions of the system in which F ( t , u , u ′ ) is replaced by ext F ( t , u , u ′ ) (= the extreme points of F ( t , u , u ′ ) ). For Dirichlet systems we show that the extremal trajectories approximate the solutions of the “convex” problem in the C 1 ( T , R N ) -norm (strong relaxation).