Search results for "RIMI"

showing 10 items of 3981 documents

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair

2015

Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. In addition, classical regulation of gene expression or activity, including gene transcription to RNA followed by translation to the protein level, by transcription factors (e.g. NF-κB, HIF-1α) and mRNA binding proteins (e.g. GAPDH, HuR) is subject to redox regulation. This review will give an update of recent discoveries in this field, and specifically highlight the impact of reactive oxygen and nitrogen species on DNA repair systems that contribute to genomic stability. Emphasis will be placed …

Genome instabilityRedox signalingRNA UntranslatedEpigenetic regulation of neurogenesisDNA RepairHuR mRNA-binding protein in the 3′-untranslated regionClinical BiochemistryHDAC histone deacetylaseReview ArticleAP-1 activator protein 1BiochemistryApe-1 apurinic/apyrimidinic endonuclease 1GPx-1 glutathione peroxidase-1Epigenesis GeneticHistonesTrx thioredoxinPHD prolylhydroxylaseBER base excision repairlcsh:QH301-705.5HO-1 heme oxygenase-1EpigenomicsGeneticsRegulation of gene expressionNox member of the NADPH oxidase familylcsh:R5-920JmjC Jumonji C domain-containing histone demethylasesHIF-1α hypoxia inducible factor-1α5-hmC 5-hydroxymethylcytosineddc:Cell biologyMMP matrix metalloproteinaseGrx glutaredoxinGAPDH glyceraldehyde-3-phosphate dehydrogenaseNrf2 nuclear factor erythroid related factor 2DNA methylationEpigeneticslcsh:Medicine (General)Oxidation-ReductionSignal Transduction5-mC 5-methylcytosineDNA repairDNA damageNF-κB nuclear factor-κBBiologyGenomic InstabilityRNS reactive nitrogen speciesROS reactive oxygen speciesNER nucleotide excision repairSOD superoxide dismutaseOxyR transcription factor (hydrogen peroxide-inducible genes activator)HumansEpigeneticsOrganic ChemistryPETN pentaerithrityl tetranitrateGene regulationOxidative StressDNMT DNA methyltransferaseGene Expression Regulationlcsh:Biology (General)AREs AU-rich elementsHAT histone acetyltransferaseKeap1 kelch-like ECH-associated protein 1BiomarkersCOPD chronic obstructive pulmonary disorderDNA DamageRedox Biology
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Factors in Assessing Recidivism Risk in Young Offenders

2020

The research aims to identify if the accumulation of protective and/or risk factors might predict the risk of recidivism in juvenile delinquents and determine the relative weight of both types of factors in the predictions themselves. The risk of criminal recidivism was assessed with the Structured Assessment of Violence Risk in Youth&mdash

Geography Planning and DevelopmentTJ807-830Relative weightManagement Monitoring Policy and LawTD194-195:CIENCIAS ECONÓMICAS [UNESCO]Renewable energy sourcesValencian communityrecidivism riskIntervention (counseling)protective factorsJuvenile delinquencyrisk factorsJuvenileGE1-3500501 psychology and cognitive sciencesadolescentsJustice (ethics)0505 lawEnvironmental effects of industries and plantsRecidivismRenewable Energy Sustainability and the Environment05 social sciencesUNESCO::CIENCIAS ECONÓMICASsustainabilityJuvenile detentionEnvironmental sciences050501 criminologyPsychology050104 developmental & child psychologyClinical psychologySustainability
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The Spanish Creation of the Philippines: The Birth of a Nation

2017

This chapter examines the human background of the country from its early settlement to the end of the Spanish colonial era. Different theories have been presented to explain the initial settlement of the country. The Austronesian societies developed a social structure and patterns of commerce that were not completely erased by the Spanish colonization following the discovery travels of Magellan and others, and the conquest of the islands by Legazpi in the sixteenth century. Spanish control meant the imposition of the Catholic Church as a powerful element of organization in the countryside, and the development of cities following colonial Spanish guidelines. Manila was central to a large mar…

GeographyAncient historyRural areaElement (criminal law)ChinaColonialismSettlement (litigation)Trade networkCONQUEST
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Analysing the presence of school-shooting related communities at social media sites

2010

Surprisingly cruel mass murders and attacks have been witnessed in the educational institutions of the Western world since the 1970s. These are often referred to as 'school shootings'. There have been over 300 known incidents around the world and the number is growing. Social network sites (SNSs) have enabled the perpetrators to express their views and intentions. Our result is that since about 2005, all major school shooters have had a presence in SNS and some have left traces that would have made possible to evaluate their intentions to carry out a rampage. A further hypothesis is that future school shooters will behave in a similar manner and would thus be traceable in the digital sphere…

GeographySocial media miningSocial networkbusiness.industryOntologyWestern worldSocial mediaCriminologyMultimedia data miningRelation (history of concept)businessSocial psychologyInternational Journal of Multimedia Intelligence and Security
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Deception and Abuse: Manifold Instances of Proximity Violence Against Sub-Saharan Women

2020

This chapter, by referring to the gender-violence binomial, highlights some of the dynamics between “resistant victims” and “proximate perpetrators” which characterize proximity violence. It presents the results of research consisting in participant observation of 18 sub-Saharan women residing in refugee facilities located in western Sicily and 16 non-directive interviews, from which three cases have been extracted.

GeographySub saharanmedia_common.quotation_subjectRefugeeVulnerabilityResistance (psychoanalysis)Participant observationDeceptionCriminologymedia_common
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Long-term effects of delayed motherhood in mice on postnatal development and behavioural traits of offspring

2003

BACKGROUND: Some epidemiological evidence tentatively suggests that children born to older parents may have lower intellectual development and maturity than children whose parents are younger. This study aims to analyse the long-term effects of delayed motherhood in mice on postnatal development and behavioural traits later in life. METHODS: Hybrid females, either at the age of 10 weeks or 51 weeks, were individually housed with a randomly selected 12-14 week old hybrid male. After a postweaning resting period of 1 week, dams were caged again with a new randomly selected 12-14 week old male. This sequence of events was repeated until old females reached the end of their reproductive life. R…

GerontologyIntellectual developmentOffspringPhysiologyMorris water navigation taskReproductive BehaviorGrowthMotor ActivityBiologyDiscrimination LearningMicePregnancySensorimotor integrationAvoidance LearningAnimalsHumansAdvanced maternal ageYoung adultMaze LearningBehavior AnimalReproductionRehabilitationReproductive lifeObstetrics and GynecologyMice Inbred C57BLReproductive MedicineAgeingModels AnimalMice Inbred CBAFemaleMaternal AgeHuman Reproduction
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Trends in high life satisfaction among adolescents in five Nordic countries 2002–2014

2019

Abstract Life satisfaction is an important indicator when assessing positive mental health aspects in populations, including among adolescents. The aim of this study was to investigate trends over time in prevalence of high life satisfaction among adolescents from five Nordic countries: Denmark, Iceland, Finland, Norway and Sweden.    We used data from four waves of the Health Behaviour in School-Aged Children study from 2002, 2006, 2010 and 2014 (n=109,847). HBSC is a school-based study examining social circumstances, health and health behaviour among 11-, 13- and 15-years olds every four years in many European and North American countries. The Cantril Ladder, an 11-step visual analogue sc…

GerontologyPohjoismaatlcsh:Social pathology. Social and public welfare. Criminologyhyvinvointilife satisfaction adolescents country comparisons Nordic countriesLife satisfactionGeneral MedicineMental healthkansainvälinen vertailucountry comparisonsPeer reviewlcsh:HV1-9960Nordic countriesnuoretadolescentsPsychologycountrycomparisonslife satisfactionlifesatisfaction
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Trends in sleeping difficulty among adolescents in five Nordic countries 2002–2014

2019

Sleep has been found to be an important factor in adolescents’ mental and physical health. The aim of the present study was to examine trends in sleep difficulty (i.e., difficulty falling asleep more often than once a week) in the Nordic countries among 11- to 15-year-olds. We analysed Nordic data from the Health Behaviour in School-aged Children study (HBSC), which is conducted every four years, looking specifically at trends in sleep difficulty over a 12-year period from 2002 to 2014. The participants were aged 11 to 15 years. The total number of participants across these years was 113,447. A large percentage (17% to 31% in 2014) of adolescents in the Nordic countries experience sleep dif…

Gerontologylcsh:Social pathology. Social and public welfare. CriminologyDifficulty Falling AsleephyvinvointiAdolescentsunettomuusuni (lepotila)lcsh:HV1-9960nuoretsleep difficultysleepdifficultyadolescentsunihäiriötPohjoismaatPhysical healthGeneral Medicinekansainvälinen vertailuSleep in non-human animalstrenditPeer reviewNordic countriesSleep difficultyNordiccountriespopulation characteristicsPsychologyterveys
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Trends in excellent self-rated health among adolescents: A comparative Nordic study

2019

Abstract Background: Excellent self-rated health (SRH) can be seen as an important component of positive health among adolescents. The aim of this paper is to examine time trends of excellent health among adolescents in five Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) between 2002 and 2014, including differences between countries, gender and age. Methods: Nordic data from the Health Behaviour in School-aged Children (HBSC) survey (including 11-, 13- and 15-year-olds) from 2002 (n = 19,009), 2006 (n = 29,656), 2010 (n = 33,232) and 2014 (n = 31,540) were analysed by design-adjusted binomial logistic regression models. Results: The trend analysis of excellent SRH for Nordi…

Gerontologytrendslcsh:Social pathology. Social and public welfare. Criminologymedia_common.quotation_subjecteducationRecessionkoettu terveysself-rated healthlcsh:HV1-9960nuoretComponent (UML)lamaadolescentsmedia_commonSelf-rated healthPohjoismaatitsearviointiTime trendsfood and beveragesGeneral Medicinekansainvälinen vertailuhumanitiesPeer reviewtrenditNordic countriesrecessionPsychologyterveysself-ratedhealth
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Quality management in patients associations. Diagnosis in the Spanish Federation of Cystic Fibrosis

2020

La Federación Española de Fibrosis Quística tiene como misión agrupar a las Asociaciones de Fibrosis Quística para mejorar la calidad de vida de las personas con Fibrosis Quística y sus familias. El despliegue de este movimiento en los últimos 20 años no ha sido igual en todas las asociaciones que lo componen. Este artículo, expone el diagnóstico de la cuestión. Con una metodología cuantitativa y cualitativa, se ha triangulando la información procedente de: análisis documental, entrevistas semiestructuradas y encuestas. Los resultados obtenidos plantean la gestión con calidad como elemento favorecedor del fortalecimiento asociativo y la figura del profesional de trabajo social como impulsor…

Gestión de calidadSocial WorkTrabajo SocialQuality managementAsociaciones de pacientesCystic FibrosisTreball socialTarget groupsSocial SciencesFibrosis QuísticaTrabajo Social.HSocial pathology. Social and public welfare. CriminologyNursingPatients associationsPacientsQuality managementHV1-9960Social workcalidadQualityHomogeneousPsychologygestión de calidadCalidadQualitative research
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