Search results for "RITU"

Ceļš: Teoloģisks un kultūrvēsturisks izdevums. Nr.52

2000

Exploratory study on the effects of biodegradable nanoparticles with drugs on malignant B cells and on a human/mouse model of Burkitt lymphoma.

2010

The aim of this study was to determine if Rituximab coated Biodegradable Nanoparticles (BNPs) loaded with Chlorambucil and Hydroxychloroquine could induce apoptosis of B-Chronic Lymphocytic Leukemia (B-CLL), MEC-1 and BJAB cells in vitro and evaluate their toxic and therapeutic effects on a Human/Mouse Model of Burkitt Lymphoma at an exploratory, proof of concept scale. We found that Rituximab-Chlorambucil-Hydroxychloroquine BNPs induce a decrease in cell viability of malignant B cells in a dose-dependent manner. The mediated cytotoxicity resulted from apoptosis, and was confirmed by monitoring the B-CLL cells after Annexin V/propidium iodide staining. Additional data revealed that these BN…

A xanthogranulomatous process resembling residual disease on endof- treatment 18f-FDG-PET/CT and Whole Body Magnetic Resonance performed on a primary…

2016

We report the case of a woman, affected by breast diffuse large B-Cell lymphoma, who developed a xanthogranulomatous process wrongly interpreted as residual disease on 18F-FDG-PET/CTand Whole Body Magnetic Resonance after treatment with ibrutinib plus standard immunochemotherapy. Newer drugs, such as immunomodulatory agents and checkpoint inhibitors, have demonstrated high effectiveness on lymphoma, but are associated with unclear imaging features such as tumor flare or pseudo-progression, related to inflammatory reactions. Wide imaging techniques availability improves diagnostic possibilities. However, the awareness of the adopted treatment strategy and its possible implications on imaging…

Four cases of progressive multifocal leukoencephalopathy in iatrogenic immunocompromised patients

2020

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by John Cunningham Virus (JCV). We report four PML cases in immunocompromised patients, respectively treated with (1) Natalizumab, (2) Rituximab, (3) autologous stem-cell transplantation, and (4) Tacrolimus. All patients underwent neurological examination, magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), JCV-DNA research on biological samples, and lymphocytes subpopulation study. All cases presented with motor, behavioural, and cognitive disorders. Visual, sensitive, and cerebellar deficits developed in three cases. MRI revealed widespread progressiv…

Ģeogrāfija. Ģeoloģija. Vides zinātne: referātu tēzes

2008

Report on the Peace Making Ceremony held in Arbore, Ethiopia, 6-9 March 1993

1993

This is the technical report of the support provided by SNV to the elders that have organised the the Peace Making ceremony in Arbore in 1993

Evans’ Syndrome: From Diagnosis to Treatment

2020

Evans’ syndrome (ES) is defined as the concomitant or sequential association of warm auto-immune haemolytic anaemia (AIHA) with immune thrombocytopenia (ITP), and less frequently autoimmune neutropenia. ES is a rare situation that represents up to 7% of AIHA and around 2% of ITP. When AIHA and ITP occurred concomitantly, the diagnosis procedure must rule out differential diagnoses such as thrombotic microangiopathies, anaemia due to bleedings complicating ITP, vitamin deficiencies, myelodysplastic syndromes, paroxysmal nocturnal haemoglobinuria, or specific conditions like HELLP when occurring during pregnancy. As for isolated auto-immune cytopenia (AIC), the determination of the primary or…

Immunotherapies for thyroid eye disease

2019

Thyroid eye disease is a complex autoimmune disorder which causes substantial morbidity. It can result in orbital disfigurement, double vision, and visual loss. Consequently, it has a substantial negative effect on quality of life, mental health, and socioeconomic status. Most signs and symptoms of thyroid eye disease (TED) can be explained by the expansion of the orbital contents. Steroids are the mainstay of treatment in TED. However, recurrence may occur once steroids are withdrawn. Furthermore, in most cases, normal orbital anatomy is not restored, and skilled rehabilitative surgery is required to reduce disfigurement, double vision, and to preserve vision. Therefore, novel, causal, and…

Cosa può dirci l’antico. Spazi, forme e funzioni dei pellegrinaggi cristiani “minori”

2016

In questa sede si pone attenzione, osservando alcuni pellegrinaggi cristiani definibili come “minori”, ad alcune questioni relative alle relazioni tra ambiente, società e luoghi sacri, alle funzioni rivestite dall’itinerario pellegrinale in rapporto alla diversa composizione delle “comunità di pellegrinaggio” e alle ragioni “religiose” che hanno potuto sostenere la continuità di frequentazione dei luoghi di culto e il reiterarsi di certe pratiche rituali. Nonostante le trasformazioni socio-culturali, il mutare delle aspettative esistenziali dei fedeli, dei sistemi di produzione, dei regimi alimentari, della consistenza demografica, il pellegrinaggio resta, infatti, un istituto religioso dif…

Geochemical constraints on the provenance and depositional setting of sedimentary rocks from the islands of Chios, Inousses and Psara, Aegean Sea, Gr…

2007

The provenance and depositional setting of Late Palaeozoic and Early Mesozoic clastic sediments from the eastern Aegean archipelago are examined here for the first time using whole-rock geochemistry and composition of detrital chrome spinel. Major- and trace-element data for Late Palaeozoic and Permo-Triassic clastic sediments from the Lower and Upper Units of Chios are compatible with an acidic to intermediate source, minor input of (ultra)mafic detritus and recycling of older sedimentary components. Chondrite-normalized REE profiles are uniform with light REE enrichments (La N /Yb N c . 7.7), negative Eu anomalies (Eu/Eu* c . 0.67) and flat heavy REE patterns (Gd N /Yb N c . 1.5), indicat…