Search results for "RT-LAMP."

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Reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) as a user-friendly system to detect SARS-CoV-2 infection: a multicentric study

2021

Although reverse transcriptase quantitative PCR remains the gold standard to perform viral detection, reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) is already used to perform diagnosis of various infections. This work reports the results of a multicentric study performed in Sicily to evaluate the diagnostic power of an RT-LAMP kit for the diagnosis of SARS-CoV-2 infection on a total of 551 samples collected in January and February 2021, revealing sensitivity, specificity, accuracy, positive and negative predictive values ≥95%. Our results suggest the potential employment of this kit as a screening test to be used where fast and reliable results are demanded without …

Multicentric studyRT-LAMP.Diagnostic powerReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2COVID-19RNA-Directed DNA PolymeraseSensitivity and SpecificityMolecular Diagnostic TechniquesHumansRNA ViralRNAViralNucleic Acid Amplification Techniques
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