Search results for "RUN"

showing 10 items of 2820 documents

Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

2019

Abstract Background A growing demand for improved physical skills and mental attitude in modern sport horses has led to strong selection for performance in many warmblood studbooks. The aim of this study was to detect genomic regions with low diversity, and therefore potentially under selection, in Swedish Warmblood horses (SWB) by analysing high-density SNP data. To investigate if such signatures could be the result of selection for equestrian sport performance, we compared our SWB SNP data with those from Exmoor ponies, a horse breed not selected for sport performance traits. Results The genomic scan for homozygous regions identified long runs of homozygosity (ROH) shared by more than 85%…

MaleGenotyping TechniquesPerformanceDIVERSITYBreedingRuns of HomozygosityHorseGenomeHISTORYInbreedingHOMOZYGOSITYGenetics & Heredity0303 health sciencesSnp dataeducation.field_of_studyHomozygoteRUNSASSOCIATIONGenomics04 agricultural and veterinary sciencesBreedDIFFERENTIATIONWarmbloodFemaleLife Sciences & BiomedicineTRAITSResearch ArticleSportsBiotechnologyGENESlcsh:QH426-470lcsh:BiotechnologyPopulationBiologyRuns of homozygosityPolymorphism Single Nucleotide03 medical and health scienceslcsh:TP248.13-248.65GeneticsAnimalsHorsesFunctional studieseducationSelection (genetic algorithm)030304 developmental biologyScience & Technology0402 animal and dairy scienceSelection signature040201 dairy & animal sciencelcsh:GeneticsBiotechnology & Applied MicrobiologyEvolutionary biologyWIDE SCANHaplotype homozygosityBMC Genomics
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Age, training, and previous experience predict race performance in long-distance inline skaters, not anthropometry

2012

Knechtle, Beat | Knechtle, Patrizia | Ruest, Christoph Alexander | Rosemann, Thomas | Lepers, Romuald; International audience; ''The association of characteristics of anthropometry, training, and previous experience with race time in 84 recreational, long-distance, inline skaters at the longest inline marathon in Europe (111 km), the Inline One-eleven in Switzerland, was investigated to identify predictor variables for performance. Age, duration per training unit, and personal best time were the only three variables related to race time in a multiple regression, while none of the 16 anthropometric variables were related. Anthropometric characteristics seem to be of no importance for a fast …

MaleGerontologyFuture studiesSWIMMING PERFORMANCEInline skating030204 cardiovascular system & hematologyRace (biology)0302 clinical medicineTRIATHLON PERFORMANCESMARATHON RUNNERSMENTAL TOUGHNESSPhysical Education and TrainingAnthropometrybiologyAge FactorsContrast (statistics)Middle AgedSensory SystemsTIMESkinfold Thickness[ SCCO.NEUR ] Cognitive science/Neurosciencesports.sport''SKIN-FOLD THICKNESSESPsychologyAdult11035 Institute of General PracticeBODY-COMPOSITIONsportsAccelerationExperimental and Cognitive Psychology610 Medicine & healthAthletic Performance03 medical and health sciences2809 Sensory SystemsHumansAssociation (psychology)ULTRA-MARATHONERSTIME''Athletes3205 Experimental and Cognitive Psychology[SCCO.NEUR]Cognitive science/NeuroscienceTraining (meteorology)030229 sport sciencesAnthropometrybiology.organism_classificationSKIN-FOLD THICKNESSESPractice PsychologicalSkatingPhysical EnduranceUPPER ARMRUNNING PERFORMANCE
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Secular trends in aerobic fitness performance in 13-18-year-old adolescents from 1976 to 2001

2009

To analyse the secular trends in aerobic fitness performance and some of its determinants (body mass index (BMI) and leisure time physical activity (LTPA)) in adolescents.Cross-sectional population-based studies in 1976 and 2001 in Finland. A stratified random sample of Finnish 13-18-year-old adolescents was studied in 1976 (n = 717; 384 boys and 333 girls) and in 2001 (n = 558; 305 boys and 253 girls). The main outcome measure was aerobic fitness, estimated with a 2000 m (for boys) and 1500 m (for girls) running test; the weight and height of participants were also measured. Self-reported weekly frequency of LTPA of at least 30 min duration and regularity of participation in organised spor…

MaleGerontologyTime FactorsAdolescentPhysical fitnessPopulationPhysical Therapy Sports Therapy and RehabilitationOverweightBody Mass IndexRunningLeisure ActivitiesOxygen ConsumptionHumansMedicineAerobic exerciseOrthopedics and Sports MedicineeducationExerciseSex Characteristicseducation.field_of_studybusiness.industryGeneral Medicinemedicine.diseaseObesityTest (assessment)Physical FitnessFemaleHealth educationmedicine.symptombusinessBody mass indexBritish Journal of Sports Medicine
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Victimisation and life satisfaction of gay and bisexual individuals in 44 European countries: the moderating role of country-level and person-level a…

2018

We examined the link between victimisation and life satisfaction for 85,301 gay and bisexual individuals across 44 European countries. We expected this negative link to be stronger when the internalised homonegativity of the victim was high (e.g. because the victim is more vulnerable) and weaker when victimisation occurs in countries that express intolerance towards homosexuality (e.g. because in such contexts victims expect victimisation more and they attribute it to their external environment). Additionally, we expected internalised homonegativity to relate negatively to life satisfaction. Multilevel analyses revealed that victimisation (i.e. verbal insults, threats of violence, minor or …

MaleHealth (social science)soziale Probleme050109 social psychologyPersonal Satisfaction20500Developmental psychologyviolenceddc:150Surveys and QuestionnairesPsychologyHomosexualityCrime VictimsGewaltSocial policymedia_common05 social sciencesHomosexualityhomosexualitypsychophysical stressLebenszufriedenheitEuropeanti-gay victimisation; internalised homonegativity; minority stress; European Values Study 2008 4th Wave Integrated Dataset. GESIS Data Archive Cologne Germany ZA4800 Dataset Version 2.0.0 (2010-11-30)Soziale Probleme und SozialdiensteBisexuality10700SozialpsychologieBisexualitätEuropa0305 other medical sciencePsychologySocial psychologyAdultSocial PsychologySocial ProblemsSexual BehaviorViktimisierungmedia_common.quotation_subjectsatisfaction with lifeMehrebenenanalyseViolenceStressVictimisation03 medical and health sciencesCountry levelHumans0501 psychology and cognitive sciences030505 public healthminorityvictimizationPublic Health Environmental and Occupational HealthLife satisfactionDiskriminierungMinority stressmulti-level analysisddc:360AttitudePsychologieMinderheitbisexualitySocial problems and servicesHomosexualitätdiscriminationCulture, Health & Sexuality
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A novel mutation of gene CBFA1/RUNX2 in cleidocranial dysplasia.

2007

Cleidocranial dysplasia (CCD) is an autosomal dominant skeletal dysplasia characterised by abnormal clavicles, patent sutures and fontanelles, supernumerary teeth, short stature, and a variety of other skeletal changes. The disease gene is CBFA1/RUNX2, which is mapped to chromosome 6p21. Inactivation of the CBFA1/RUNX2 gene by mutations is involved in the skeletal defects that occur in patients with CCD. CBFA1/RUNX2 controls the differentiation of precursor cells into osteoblasts and is essential for membranous as well as endochondral bone formation. In this study of a 14-yr-old boy with typical CCD phenotype, the authors found a novel CBFA1/RUNX2 gene mutation. All of the amplified segment…

MaleHeterozygoteAdolescentDNA Mutational AnalysisCore Binding Factor Alpha 1 SubunitPolymerase Chain ReactionPedigreeAdolescent Chromosomes Human Pair 6 Cleidocranial Dysplasia/genetics* Cleidocranial Dysplasia/pathology Codon Nonsense/genetics* Core Binding Factor Alpha 1 Subunit/genetics* DNA Mutational Analysis DNA Primers/chemistry Female Gene Silencing Heterozygote Humans Male Pedigree Point Mutation* Polymerase Chain Reactioncleidocranial dysplasiaCodon NonsenseCBFA1/RUNX2HumansPoint MutationChromosomes Human Pair 6Femalegene mutationGene SilencingCleidocranial DysplasiaDNA Primers
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Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe

2016

Transmitted human immunodeficiency virus drug resistance in Europe is stable at around 8%. The impact of baseline mutation patterns on susceptibility to antiretroviral drugs should be addressed using clinical guidelines. The impact on baseline susceptibility is largest for nonnucleoside reverse transcriptase inhibitors.

MaleHuman immunodeficiency virus 1EtravirineRNA directed DNA polymerase inhibitordarunavirHIV InfectionsSettore MED/42 - Igiene Generale E Applicata:Disciplines and Occupations::Health Occupations::Medicine::Public Health [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Salud públicageneticsInhibidores de proteasas:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Prevalence [Medical Subject Headings]atazanavirmedia_commontransmission:Geographicals::Geographic Locations::Europe [Medical Subject Headings]3. Good healthmicrobial sensitivity testpriority journalEurope ; HIV-1 ; antiretroviral therapy ; drug resistance ; transmissionHIV/AIDSlamivudineReverse Transcriptase Inhibitors/pharmacologyanti human immunodeficiency virus agentDrugMicrobiology (medical)medicine.medical_specialtyantiviral susceptibility:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation [Medical Subject Headings]media_common.quotation_subjectantiretroviral therapy030106 microbiologyHIV Infections/drug therapy:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents::Anti-Retroviral Agents::Reverse Transcriptase Inhibitors [Medical Subject Headings]Microbial Sensitivity TestsRILPIVIRINEArticleEFAVIRENZ03 medical and health sciencestransmitted drug resistanceSDG 3 - Good Health and Well-beingHumansTransmissionhuman:Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance [Medical Subject Headings]REVERSE-TRANSCRIPTASE INHIBITORSRilpivirinaINTEGRASEMUTATIONSabacavirmajor clinical studyVirologyInfecciones por VIHRegimenAntiretroviral therapy; Drug resistance; Europe; HIV-1; Transmission; Medicine (all); Microbiology (medical); Infectious DiseaseschemistryDrug resistance:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 1-Ring::Oxazines::Benzoxazines [Medical Subject Headings]MutationHIV-10301 basic medicinenevirapineDrug resistanceCommunicable diseases:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence Intervals [Medical Subject Headings]chemistry.chemical_compoundantiviral therapyINFECTIONMedicine and Health SciencesPrevalence:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Surveys and Questionnaires [Medical Subject Headings]ViralNon-U.S. Gov'tReverse-transcriptase inhibitorantiretrovirus agentResearch Support Non-U.S. Gov'tMedicine (all)Human immunodeficiency virus infected patientMiddle AgedvirologyPREVALENCEAntiretroviral therapyEncuestas y CuestionariosANTIRETROVIRAL TREATMENTEuropeInfectious DiseasesHIV-1/drug effectsHIV Protease Inhibitors/pharmacologyRilpivirineReverse Transcriptase Inhibitors:Diseases::Immune System Diseases::Immunologic Deficiency Syndromes::HIV Infections [Medical Subject Headings]FemaleHIV drug resistancemedicine.drugAdultHuman immunodeficiency virus proteinase inhibitor:Chemicals and Drugs::Organic Chemicals::Nitriles::Rilpivirine [Medical Subject Headings]EfavirenzAnti-HIV AgentsResearch SupportResistencia a medicamentosSettore MED/17 - MALATTIE INFETTIVEantiviral resistanceInternal medicineAnti-HIV Agents/pharmacologyDrug Resistance ViralJournal Articlemedicine:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protease Inhibitors [Medical Subject Headings]abacavir plus lamivudineEuropa (Continente)Antiretroviral therapy; Drug resistance; Europe; HIV-1; Transmission; Adult; Anti-HIV Agents; Drug Resistance Viral; Europe; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation; Prevalence; Reverse Transcriptase Inhibitors; Microbiology (medical); Infectious DiseasesemtricitabinenonhumanIntervalos de confianzadrug resistanceMutaciónAntiretroviral therapy; Drug resistance; Europe; HIV-1; Transmissionbusiness.industryHIVpredictionInhibidores de la transcriptasa inversaHIV Protease InhibitorsHuman immunodeficiency virus 1 infectiontenofovirINDIVIDUALSDrug Resistance Viral/geneticsBenzoxazinasETRAVIRINEdrug effects3121 General medicine internal medicine and other clinical medicinePrevalenciabusiness
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Validity and reliability of an inertial sensor device for specific running patterns in soccer

2021

Electronic performance tracking devices are largely employed in team sports to monitor performance and improve training. To date, global positioning system (GPS) based devices are those mainly used in soccer training. The aim of this study was to analyse the validity and reliability of the inertial sensor device (ISD) in monitoring distance and speed in a soccer-specific circuit and how their performance compare to a GPS system. 44 young male soccer players (age: 14.9 ± 1.1, range 9–16, years, height: 1.65 ± 0.10 m, body mass: 56.3 ± 8.9 kg) playing in a non-professional soccer team in Italy, participated in the study. We assessed the players trough a soccer running sport-specific circuit. …

MaleInertial frame of referenceMean squared errorAdolescentGPSValidityTP1-1185Athletic PerformanceBiochemistryArticleAnalytical ChemistryInertial sensorRunningStatisticsSoccerRange (statistics)HumansElectrical and Electronic EngineeringChildInstrumentationMathematicsSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' Sportivebusiness.industryChemical technologyReproducibility of ResultsTracking systemAtomic and Molecular Physics and OpticsAssisted GPSGlobal Positioning SystemGeographic Information SystemsData monitoringPerformance monitoringbusinessData trackingSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' Motorie
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Differences in gender and performance in off-road triathlon.

2010

The aims of this study were: (1) to examine performance trends and compare elite male and female athletes at the off-road triathlon (1.5-km swim, 30-km mountain biking, and 11-km trail running) world championships since its inception in 1996, and (2) to compare gender-related differences between off-road triathlon and conventional road-based triathlon. Linear regression analyses and ANOVA were used to examine performance trends and differences between the sexes. Elite male performance times stabilized over the 2005-2009 period, whereas elite female performance times continued to improve, especially for the run leg. Differences in performance times between the sexes were less marked in swimm…

MaleInjury controlAccident preventionMountain bikingPhysical ExertionPoison controlPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceRunningSex FactorsSex factorsHumansOrthopedics and Sports MedicinePower outputSimulationSwimmingAnalysis of VariancebiologyAthletesbiology.organism_classificationBicyclingGeographyLinear ModelsFemaleCyclingDemographyJournal of sports sciences
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Age, pathogen exposure, but not maternal care shape offspring immunity in an insect with facultative family life.

2016

Background To optimize their resistance against pathogen infection, individuals are expected to find the right balance between investing into the immune system and other life history traits. In vertebrates, several factors were shown to critically affect the direction of this balance, such as the developmental stage of an individual, its current risk of infection and/or its access to external help such as parental care. However, the independent and/or interactive effects of these factors on immunity remain poorly studied in insects. Results Here, we manipulated maternal presence and pathogen exposure in families of the European earwig Forficula auricularia to measure whether and how the sur…

MaleInsectaDevelopmental stageTrade-offForficula auriculariaBiological EvolutionInstarFamily lifeInsect immunityAnimalsFemaleMaternal BehaviorMetarhizium brunneumResearch ArticleBMC evolutionary biology
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Kinematics of obstacle clearance in the rat

2010

Although the rat has become the favourite animal model in preclinical research on locomotion, studies designed to assess the strategy used by rats to avoid obstacle are lacking. Using an optoelectronic 3D motion analysis system, we therefore, compared the step pattern, timing and length variables of locomotor cycles, trajectories and joint angles of limbs when rats step between and over obstacles (3 cm-high) fixed on a treadmill belt (25 cm/s). Motion in all four limbs of adult animals with an initial age of 11 weeks was serially recorded for a period of 10 weeks. The results showed that obstacle clearance is associated with the reorganization of the basic step pattern resulting in increase…

MaleKinematicsBiologyRunningBehavioral NeuroscienceQuadrupedalismForelimbObstacle avoidancemedicineAnimalsRats WistarTreadmillGaitBiomechanicsAnatomyGaitBiomechanical PhenomenaHindlimbRatsmedicine.anatomical_structureData Interpretation StatisticalSpace PerceptionObstacleJointsForelimbLocomotionBehavioural Brain Research
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