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showing 10 items of 8895 documents

Isthmic Spondylolisthesis is Associated with Less Revisions for Adjacent Segment Disease After Lumbar Spine Fusion Than Degenerative Spinal Condition…

2021

Objective: We aim to compare the rate of revisions for adjacent segment disease (ASD) after lumbar spine fusion (LSF) surgery between patients with isthmic spondylolisthesis (IS) and degenerative lumbar spine disorders (DLSD). Summary of Background Data: ASD is a major reason for late reoperations after LSF surgery. Several risk factors are linked to the progression of ASD, but the understanding of the underlying mechanisms is imperfect. If IS infrequently becomes complicated with ASD, it would emphasize the role of the ongoing degenerative process in spine in the development of ASD. Methods: 365 consecutive patients that underwent elective LSF surgery were followed up for an average of 9.7…

medicine.medical_specialtyadjacent segment diseaseLumbar spine fusionspondylolisteesinikamavälilevyn rappeumaIsthmic spondylolisthesisleikkaushoitolannerankaisthmic spondylolisthesisselkäsairaudetdegenerative spinal disordersMedicineOrthopedics and Sports Medicinerevisionsspinal stenosisbusiness.industry10 year follow upadjacent segment pathologydegenerative lumbar spine disordersdegenerative spondylolisthesis3126 Surgery anesthesiology intensive care radiologySurgeryhoitotuloksetNeurology (clinical)Adjacent segment diseaselumbar spine fusionbusiness
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Definition of the Rectum An International, Expert-based Delphi Consensus

2019

Mini: A radiological, anatomic distinction between the rectum and sigmoid colon was agreed by consensus of international experts in rectal cancer using the Delphi Technique. Use of this landmark, “the sigmoid take-off,” may harmonize efforts in research and clinical practice to improve patient outcomes. Background: The wide global variation in the definition of the rectum has led to significant inconsistencies in trial recruitment, clinical management, and outcomes. Surgical technique and use of preoperative treatment for a cancer of the rectum and sigmoid colon are radically different and dependent on the local definitions employed by the clinical team. A consensus definition of the rectum…

medicine.medical_specialtyanatomyRESECTIONConsensusDelphi TechniqueColorectal cancerAttitude of Health PersonnelDelphi methodRectumMesorectumGUIDELINESdigestive system03 medical and health sciencesAll institutes and research themes of the Radboud University Medical Center0302 clinical medicineColon SigmoidCOLONTumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14]MANAGEMENTmedicineHumansPREOPERATIVE RADIOTHERAPYmedicine.diagnostic_testbusiness.industryRectal NeoplasmsGeneral surgeryRectumSigmoid colonMagnetic resonance imagingSigmoid functionmedicine.diseaseCANCERdigestive system diseasessigmoidmedicine.anatomical_structure030220 oncology & carcinogenesisRadiological weapon030211 gastroenterology & hepatologySurgerybusinessPOSTOPERATIVE CHEMORADIOTHERAPYMRIAnnals of Surgery
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Presence of thyroid hormones in ascidian larvae and their involvement in metamorphosis

2001

In this study we investigated the presence and localization of thyroxine in Ciona intestinalis larvae and its involvement in metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown. In vivo treatment of swimming larvae with exogenous L-thyroxine and thiourea, and in vitro experiments utilizing high performance liquid chromatography, radioimmunoassay, and immunoperoxidase staining demonstrate the presence of thyroxine at the larval stage. This suggests that this hormone may participate in the control of metamorphosis and thus play a different role from that observed in adults.

medicine.medical_specialtyanimal structuresmedia_common.quotation_subjectRadioimmunoassayIn vivoInternal medicinemedicineAnimalsCiona intestinalisUrochordataMetamorphosisChromatography High Pressure LiquidSwimmingmedia_commonLarvabiologyfungiMetamorphosis BiologicalRadioimmunoassayGeneral Medicinebiology.organism_classificationIn vitroThyroxineEndocrinologyLarvaThyroid hormonesAnimal Science and ZoologyHormoneJournal of Experimental Zoology
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Intraoral soft tissue lipomas: clinicopathological features from 91 cases diagnosed in a single Oral Pathology service.

2020

Background intraoral soft tissue lipomas are relatively uncommon mesenchymal neoplasms. Few papers have been published comparing the clinicopathological features of these tumors in different populations. The aim of the present study was to analyze the clinicopathological features from intraoral soft tissue lipomas diagnosed in a Brazilian population. Material and Methods all cases diagnosed as intraoral soft tissue lipomas in an Oral Pathology laboratory from 2005 to 2019 were retrieved and descriptively analyzed; statistical analysis was performed for comparison of the clinical and demographic parameters. Results 91 intraoral lipomas were retrieved, including 56 lipomas, 30 fibrolipomas, 2…

medicine.medical_specialtybinaural beatsBuccal mucosaTonguedental anxietyOral and maxillofacial pathologymedicineotorhinolaryngologic diseasesHumansStatistical analysisGeneral DentistryUNESCO:CIENCIAS MÉDICASOral Medicine and Pathologybusiness.industryResearchMouth MucosaSoft tissueMean ageLipomaMiddle Agedmedicine.disease432 hz musicbody regionsstomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyPathology OralClinicopathological featuresSurgeryFemaleMouth NeoplasmsRadiologyLipomabusinessBrazilMedicina oral, patologia oral y cirugia bucal
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Characterisation of [11C]PR04.MZ in Papio anubis baboon: A selective high-affinity radioligand for quantitative imaging of the dopamine transporter

2012

N-(4-fluorobut-2-yn-1-yl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane (PR04.MZ, 1) is a PET radioligand for the non-invasive exploration of the function of the cerebral dopamine transporter (DAT). A reliable automated process for routine production of the carbon-11 labelled analogue [11C]PR04.MZ ([11C]-1) has been developed using GMP compliant equipment. An adult female Papio anubis baboon was studied using a test–retest protocol with [11C]-1 in order to assess test–retest reliability, metabolism and CNS distribution profile of the tracer in non-human primates. Blood sampling was performed throughout the studies for determination of the free fraction in plasma (fP), plasma input functions and m…

medicine.medical_specialtybiologyChemistryPutamenOrganic ChemistryClinical BiochemistryDopaminergicCaudate nucleusPharmaceutical ScienceBiochemistryEndocrinologyDopaminebiology.animalInternal medicineDrug Discoverybiology.proteinmedicineRadioligandMolecular MedicineMolecular BiologyBaboonDopamine transportermedicine.drugBlood samplingBioorganic & Medicinal Chemistry Letters
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Atrial fibrillation in athletes and non-athletes: evidence of different causative mechanisms

2021

medicine.medical_specialtybiologybusiness.industryAthletesMEDLINEAtrial fibrillationGeneral Medicinemedicine.diseasebiology.organism_classificationInternal medicineMedicineRadiology Nuclear Medicine and imagingCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal - Cardiovascular Imaging
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SPECT-Untersuchungen mit dem 123I-markierten Dopamintransporter-Liganden FP-CIT (DaTSCANTM)

2019

ZusammenfassungDie S1-Leitlinie soll bei der Indikationsstellung, Durchführung, Interpretation und Befundung von SPECT-Untersuchungen des Dopamintransporters (DAT) mit DaTSCANTM unterstützen. Gegenüber der Vorgängerversion von 2007 berücksichtigt die vorliegende Aktualisierung und Überarbeitung die neuere wissenschaftliche Literatur, zwischenzeitlich veröffentlichte Guidelines der europäischen (EANM) und amerikanischen Fachgesellschaften (SNM), sowie die aktuelle Fassung der S3-Leitlinie „Idiopathisches Parkinson-Syndrom“ der Deutschen Gesellschaft für Neurologie. Zudem finden neue technische Möglichkeiten Berücksichtigung.

medicine.medical_specialtybiologybusiness.industrymedicinebiology.proteinRadiology Nuclear Medicine and imagingMedical physicsGeneral MedicineGuidelinebusinessDopamine transporterNuklearmedizin
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Scarf and Akin osteotomies for moderate and severe hallux valgus

2008

Abstract Background The scarf and the combined scarf-Akin procedures are reliable therapeutic tools and can obtain effective correction of symptomatic moderate to severe hallux valgus deformities. Methods The data from 30 patients (37 feet) with moderate to severe hallux valgus deformity who had scarf osteotomies have been retrospectively reviewed. 32 Akin and 77 Weil osteotomies were also carried out at the same stage. The average follow-up was 22 months. Standardized methods of radiographic and clinical data collection were obtained before and after surgery. Patient satisfaction was assessed at follow-up. Results Radiological assessment revealed a significant improvement ( p p Conclusions…

medicine.medical_specialtybiologybusiness.industrymedicine.medical_treatmentRadiographyRetrospective cohort studymedicine.diseaseOsteotomybiology.organism_classificationSurgerybody regionsValgusPatient satisfactionRadiological weaponSeverity of illnessmedicineOrthopedics and Sports MedicinebusinessValgus deformityFoot and Ankle Surgery
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Tomografía computarizada multidetector en el traumatismo facial: informe estructurado y observaciones clave para un abordaje sistemático

2019

Facial fractures, often related to traffic accidents, assault, work-related accidents, or falls, account for a considerable number of emergencies in our hospitals and are associated with high morbidity and mortality. Multidetector computed tomography (MDCT) is the imaging technique of choice in this scenario because it is widely available, fast, and useful for characterizing facial fractures and associated complications, including those located in the head. For all these reasons, MDCT is fundamental in the clinical management of these patients and in planning surgery. This paper describes the radiological anatomy of the facial region, underlining the importance of the facial buttresses, and…

medicine.medical_specialtybusiness.industry030206 dentistryRadiological anatomy030218 nuclear medicine & medical imaging03 medical and health sciencesHigh morbidity0302 clinical medicineMultidetector computed tomographymedicineRadiology Nuclear Medicine and imagingRadiologyImaging techniqueFacial regionbusinessRadiología
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Correlation of Vertebral Absolute Axial Rotations in CAD 3D Models of Adolescent Idiopathic Scoliosis Non-Invasively Diagnosed

2019

This paper presents preliminary results on non-invasive optical diagnosis of patient with adolescent idiopathic scoliosis (AIS) with recently developed tool ScolioSIM. This tool generates intrinsic and extrinsic indicators of the spinal deformity and 3D CAD (Computer-aided Design) deformity model based only on a digitalized dorsal surface of the examined patient. Our primary focus in this paper are absolute axial rotations (AAR) of each vertebra in AIS patients and their correlations. Clinical relevance of this research is high, as we intend to avoid traditional methods which rely on highly complicated reading and measuring of AARs on planar x-ray films, as these methods involve ionizing ra…

medicine.medical_specialtybusiness.industry3d modelCADIdiopathic scoliosisScoliosismedicine.diseaseVertebraCorrelationmedicine.anatomical_structureOptical diagnosismedicineDeformityRadiologymedicine.symptombusiness2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE)
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