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PECULIARE EVOLUZIONE DELLA SEMEIOTICA NEURORADIOLOGICA DI UN CASO DI MALATTIA DEMIELINIZZANTE CON LESIONI PSEUDOTUMORALI
2013
SCOPO DEL LAVORO Presentiamo un caso di una paziente di 24 anni che giunge alla nostra attenzione per la comparsa di disartria come quadro clinico d’esordio di una forma aggressiva di malattia demielinizzante di cui si valuta l’atipica evoluzione neuroradiologica delle lesioni pseudotumorali che la caratterizzano e le possibili diagnosi differenziali. MATERIALI E METODI La paziente dopo una prima valutazione in PS è stata sottoposta a TC encefalo, ricoverata presso l’U.O. di Neurologia, sottoposta a controlli RM seriati (anche con tecniche avanzate); durante la degenza è stata inoltre effettuata una biopsia stereotassica. RISULTATI La TC ha rilevato almeno tre lesioni ipodense: a sinistra…
CARATTERISTICHE NEURORADIOLOGICHE DI UN CASO DI SCLEROSI TUBEROSA DIAGNOSTICATO IN ETÀ ADULTA
2013
SCOPO DEL LAVORO: presentiamo un caso di Sclerosi Tuberosa (Tuberous sclerosis complex, TSC; anche nota come Sindrome di Bourneville-Pringle) diagnosticato tardivamente grazie al sospetto posto dalle indagini neuroradiologiche eseguite in una paziente di 40 anni con in anamnesi ritardo mentale, crisi epilettiche e disturbi del visus.MATERIALI E METODI: la paziente si presenza alla nostra attenzione per un episodio di disorientamento e confusione mentale; dopo una prima valutazione in PS veniva eseguita una TC dell’encefalo in tecnica sequenziale (Siemens SOMATON AS+, 128 strati) e trasferita presso l’U.O.C. di Neurologia. In seguito, per una migliore caratterizzazione dei reperti descritti …
Trattamento sclerotizzante retrogrado percutaneo del varicocele e risultati sui parametri seminali e sulla fertilità.
2006
Comunicazione orale per XIII Congresso Nazionale della Società Italiana di Andrologia. Milano, 26-29 settembre 2006
Detecting cellular network anomalies using the knowledge discovery process
2015
Analytical companies unanimously forecast the exponential growth of mobile traffic consumption over the next five years. The densification of a network structure with small cells is regarded as a key solution to meet growing capacity demands. The manual management of a multi-layer network is a very expensive, error prone, and sluggish process. Hence, the automation of the whole life cycle of network operation is highly anticipated. To this aim 3GPP introduces a self-management concept referred to as SON. It is envisioned that SON updates information concerning the latest network conditions through the MDT mecha- nism. MDT enables a network operator to collect radio and service quality measurem…
Itsemurhatartunnan taikauskosta: The Moth Diaries (2011) ja 13 Reasons Why (2017)
2018
Artikkeli käsittelee kahden itsemurhaa kuvaavan populaarikulttuurin tapausesimerkin, The Moth Diaries -elokuvan ja 13 Reasons Why -sarjan, ja tabun käsitteen välityksellä itsemurhaan liitettyä tartunnan pelkoa ja tämän pelon ilmenemistä viihteen ja median representaatioita säätelevässä Werther-efektissä. Keväällä 2017 julkaistun kohutun 13 Reasons Why -Netflix-sarjan ensimmäisen kauden vastaanotto ilmentää sosiologien, psykologien ja kansanterveystieteilijöiden tunnetuksi tekemää Werther-efektiä, median välittämäksi pelättyä itsemurhatartuntaa. Kanadalainen kauhudraama The Moth Diaries (2011) taas käsittelee sisällössään vanhemmalta lapselle periytyvää itsemurhatartuntaa vampyyrin hahmon vä…
Multi-Chip RFID Antenna Integrating Shape-Memory Alloys for Detection of Thermal Thresholds
2011
Low-cost wireless measurement of objects' temperature is one of the greatest expectation of radiofrequency identification technology for the so many applications in cold supply-chain control and safety assessment in general. In this context, the paper proposes a dual-chip UHF tag embedding shape memory alloys (SMA) able to transform the variation of the tagged item's temperature into a permanent change of antenna radiation features. This event-driven antenna is hence able to selectively activate the embedded microchips according to the temperature above or below a given threshold. A general design methodology for the resulting two-ports tag antenna is here introduced and then applied to pro…
A Multi-Projector Calibration Method for Virtual Reality Simulators with Analytically Defined Screens
2017
The geometric calibration of projectors is a demanding task, particularly for the industry of virtual reality simulators. Different methods have been developed during the last decades to retrieve the intrinsic and extrinsic parameters of projectors, most of them being based on planar homographies and some requiring an extended calibration process. The aim of our research work is to design a fast and user-friendly method to provide multi-projector calibration on analytically defined screens, where a sample is shown for a virtual reality Formula 1 simulator that has a cylindrical screen. The proposed method results from the combination of surveying, photogrammetry and image processing approac…
Yleisradion tv-tuottaja sisäisenä yrittäjänä : yksilö ja organisaatio
2013
Julkisen palvelun yleisradiotoimintaa harjoittava Yleisradio on oligopolistisia piirteitä omaavilla kotimarkkinoilla merkittävin rahoittaja, tuottaja ja ostaja tv- ja elokuvatuotantoyrityksien tuotannoille. Nämä kokoluokaltaan pääosin pienet, riskipitoista, mutta mittavia investointeja vaativaa liiketoimintaa harjoittavat yritykset tekevät puolestaan yhteistyötä muiden luovalle toimialalle kuuluvien yrityksien kanssa. Tutkimuksen tarkoituksena ja tavoitteena olikin parantaa ja tehostaa Yleisradion toimintaa sisäisen yrittäjyyden avulla, pyrkien takaamaan siten sekä yhtiön että koko luovan toimialan toiminnan jatkuvuus ja tulevaisuus. Tutkimuskohteena oli yhtiön suurimmat vuosittaiset kustan…
Fragment‐ and Negative Image‐Based Screening of Phosphodiesterase 10A Inhibitors
2019
A novel virtual screening methodology called fragment‐ and negative image‐based (F‐NiB) screening is introduced and tested experimentally using phosphodiesterase 10A (PDE10A) as a case study. Potent PDE10A‐specific small‐molecule inhibitors are actively sought after for their antipsychotic and neuroprotective effects. The F‐NiB combines features from both fragment‐based drug discovery and negative image‐based (NIB) screening methodologies to facilitate rational drug discovery. The selected structural parts of protein‐bound ligand(s) are seamlessly combined with the negative image of the target's ligand‐binding cavity. This cavity‐ and fragment‐based hybrid model, namely its shape and electr…
Psychometric Properties of the Scoliosis Research Society Questionnaire (Version 22r) Domains Among Adults With Spinal Deformity : A Rasch Measuremen…
2022
Objective: Adults with degenerative spinal deformity (ASD) have lower health-related quality of life (HRQL) compared to the general population. Applying Rasch Measurement Theory (RMT), this study tested the revised Scoliosis Research Society-22 (SRS-22r) HRQL instrument among symptomatic adult patients with degenerative spinal disorders and varying degrees of ASD. Methods: SRS-22r data from 637 outpatient spine clinic patients with degenerative spine conditions were investigated for unidimensionality, item/scale fit, differential item functioning (DIF), scale coverage/targeting, and person separation index (PSI) using RMT. Results: Unidimensionality of the SRS-22r was not supported for eith…