Search results for "Rapid"

showing 10 items of 1173 documents

Evaluation of a mass spectrometry and Vitek 2 combined protocol for rapid identification and susceptibility testing of Enterobacterales directly from…

2020

Abstract Objective The aim was to evaluate a rapid method which would combine identification and susceptibility testing directly from positive blood cultures for Gram-negative bacilli of the Enterobacterales. Material and methods Gram-negative rods from blood cultures were directly identified by MALDI-TOF. Samples with Enterobacterales were selected for direct antimicrobial susceptibility testing by Vitek 2. The results were compared to those obtained with our laboratory's standard method. Results MALDI-TOF directly from blood cultures identified correctly 83% of the samples. Enterobacterales (n = 68) were identified at gender and species level in 85% of blood cultures with a score >1.7. In…

0301 basic medicineMicrobiology (medical)medicine.medical_specialtySusceptibility testing030106 microbiologyAntimicrobial susceptibilityBacteremiaMicrobial Sensitivity Tests03 medical and health sciences0302 clinical medicineSpecies levelEnterobacteriaceaeInternal medicineEnterobacteralesmedicineHumans030212 general & internal medicineProtocol (science)business.industryAnti-Bacterial AgentsRapid identificationCiprofloxacinAmikacinBlood CultureSpectrometry Mass Matrix-Assisted Laser Desorption-Ionizationbusinessmedicine.drugEnfermedades infecciosas y microbiologia clinica (English ed.)
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Expansion of permanent first molars with rapid maxillary expansion appliance anchored on primary second molars

2018

Background To evaluate how the amount of expansion of the primary second molars, the patient's age, and the skeletal maturation stage influence the amount of expansion at the level of the permanent first molars. Material and methods Fifty-five patients aged between 6 and 11 years with a cervical vertebral maturation stage of CS1 or CS2 were retrospectively selected. The intermolar width was measured before and after expansion to evaluate the amount of expansion achieved at the level of the primary second molars and the permanent first molars. Stepwise multiple linear regression was used to evaluate how the amount of primary molars expansion, the patient's age, and the cervical vertebral mat…

0301 basic medicineOrthodonticsMolarbusiness.industryResearchTransverse maxillary deficiencyOrthodontics030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Maxillary expansionTransversal deficiencyMandibular second molar03 medical and health sciences030104 developmental biology0302 clinical medicineSkeletal maturationstomatognathic systemMaxillary expansion; Primary molars; Transversal deficiency; Dentistry (all)UNESCO::CIENCIAS MÉDICASPrimary molarsDentistry (all)MedicinebusinessGeneral DentistryRapid maxillary expansion appliance
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NESSie.jl – Efficient and intuitive finite element and boundary element methods for nonlocal protein electrostatics in the Julia language

2018

Abstract The development of scientific software can be generally characterized by an initial phase of rapid prototyping and the subsequent transition to computationally efficient production code. Unfortunately, most programming languages are not well-suited for both tasks at the same time, commonly resulting in a considerable extension of the development time. The cross-platform and open-source Julia language aims at closing the gap between prototype and production code by providing a usability comparable to Python or MATLAB alongside high-performance capabilities known from C and C++ in a single programming language. In this paper, we present efficient protein electrostatics computations a…

0301 basic medicineRapid prototypingGeneral Computer Sciencebusiness.industryComputer scienceComputationUsabilityPython (programming language)Finite element methodTheoretical Computer ScienceNESSIEComputational science03 medical and health sciences030104 developmental biologyModeling and SimulationbusinessMATLABBoundary element methodcomputercomputer.programming_languageJournal of Computational Science
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Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia—Relevance for Mental Diseases

2021

The heteroreceptor complexes present a novel biological principle for signal integration. These complexes and their allosteric receptor–receptor interactions are bidirectional and novel targets for treatment of CNS diseases including mental diseases. The existence of D2R-5-HT2AR heterocomplexes can help explain the anti-schizophrenic effects of atypical antipsychotic drugs not only based on blockade of 5-HT2AR and of D2R in higher doses but also based on blocking the allosteric enhancement of D2R protomer signaling by 5-HT2AR protomer activation. This research opens a new understanding of the integration of DA and 5-HT signals released from DA and 5-HT nerve terminal networks. The biologica…

0301 basic medicineReviewheteroreceptor complexesTropomyosin receptor kinase BReceptor tyrosine kinasechemistry.chemical_compound0302 clinical medicineG protein-coupled receptorsserotonin receptorsReceptor Serotonin 5-HT2ABiology (General)astrogliabiologyChemistryMental DisordersBrainGeneral MedicineAntidepressive AgentsdepressionG protein-coupled receptors; astroglia; depression; heteroreceptor complexes; rapid antidepressant drugs; receptor tyrosine kinase; serotonin receptors.medicine.symptomAntipsychotic AgentsSerotonergic NeuronsSignal TransductionProto-oncogene tyrosine-protein kinase Srcserotonin receptorheteroreceptor complexeQH301-705.5Astroglia; Depression; G protein-coupled receptors; Heteroreceptor complexes; Rapid antidepressant drugs; Receptor tyrosine kinase; Serotonin receptors;Allosteric regulationserotonin receptors heteroreceptor complexes depression astroglia receptor tyrosine kinase rapid antidepressant drugs G protein-coupled receptors.depression astroglia receptor tyrosine kinase rapid antidepressant drugs G protein-coupled receptorsHeteroreceptorNO03 medical and health sciencesmedicineAnimalsHumansReceptor Fibroblast Growth Factor Type 1rapid antidepressant drugsG protein-coupled receptorReceptors Dopamine D2Dopaminergic NeuronsTyrosine phosphorylationReceptor Cross-TalkReceptor Galanin Type 1Receptor Galanin Type 2030104 developmental biologyMechanism of actionAstrocytesreceptor tyrosine kinasebiology.proteinReceptors Serotonin 5-HT1Neuroscience030217 neurology & neurosurgeryCells
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Non-Rapid Eye Movement Sleep Parasomnias and Migraine: A Role of Orexinergic Projections

2018

Introduction: Sleep and migraine share a common pathophysiological substrate, although the underlying mechanisms are unknown. The serotonergic and orexinergic systems are both involved in the regulation of sleep/wake cycle, and numerous studies show that both are involved in the migraine etiopathogenesis. These two systems are anatomically and functionally interconnected. Our hypothesis is that in migraine a dysfunction of orexinergic projections on the median raphe (MR) nuclei, interfering with serotonergic regulation, may cause Non-Rapid Eye Movement parasomnias, such as somnambulism. Hypothesis/theory: Acting on the serotonergic neurons of the raphe nuclei, the dysfunction of orexinergic…

0301 basic medicineSerotonergic systemMigraine; Orexinergic system; Pro-inflammatory peptides; Serotonergic system; Sleep-wake rhythm; Neurology; Neurology (clinical)Substance PCalcitonin gene-related peptidePro-inflammatory peptideSerotonergicNon-rapid eye movement sleeplcsh:RC346-429sleep–wake rhythmMigraine; Orexinergic system; Pro-inflammatory peptides; Serotonergic system; Sleep-wake rhythm;Settore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'Educazione03 medical and health sciencesTrigeminal ganglionchemistry.chemical_compound0302 clinical medicinePro-inflammatory peptidesSleep-wake rhythmHypothesis and TheoryMedicinelcsh:Neurology. Diseases of the nervous systemMigraineMigraine; Orexinergic system; Pro-inflammatory peptides; Serotonergic system; Sleep-wake rhythmbusiness.industryOrexinergic systemserotonergic system orexinergic system sleep–wake rhythm migraine pro-inflammatory peptidesSettore MED/39 - Neuropsichiatria InfantileOrexin030104 developmental biologyNeurologychemistryNeurology (clinical)SerotoninbusinessRaphe nucleiNeuroscience030217 neurology & neurosurgeryNeuroscienceFrontiers in Neurology
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The Importance of Developing Electrochemical Sensors Based on Molecularly Imprinted Polymers for a Rapid Detection of Antioxidants

2021

International audience; This review aims to pin out the importance of developing a technique for rapid detection of antioxidants, based on molecular imprinting techniques. It covers three major areas that have made great progress over the years in the field of research, namely: antioxidants characterization, molecular imprinting and electrochemistry, alone or combined. It also reveals the importance of bringing these three areas together for a good evaluation of antioxidants in a simple or complex medium, based on selectivity and specificity. Although numerous studies have associated antioxidants with molecular imprinting, or antioxidants with electrochemistry, but even electrochemistry wit…

0301 basic medicinesol-gel techniquePhysiologyClinical Biochemistryelectrochemical sensorNanotechnologyReviewBiochemistryRapid detection03 medical and health sciences0302 clinical medicine[SDV.IDA]Life Sciences [q-bio]/Food engineering[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMolecular Biologyscreen printed electrodesChemistrylcsh:RM1-950Molecularly imprinted polymerCell Biologyradical polymerizationcyclic voltammetrylcsh:Therapeutics. Pharmacologyantioxidants030104 developmental biologyindustrial applicationsmolecular imprintingMolecular imprinting030217 neurology & neurosurgerydifferential pulse voltammetryAntioxidants
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From bus to tramway: Is there an economic impact of substituting a rapid mass transit system? An empirical investigation accounting for anticipation …

2018

Abstract Hedonic pricing models and price equations have been extensively used to retrieve the implicit prices of urban externalities through real estate markets. Many applications have been devoted to investigating the impact of new mass transit systems, such as rail infrastructures. However, the implementation of such infrastructures usually takes some time and markets can react with an anticipation effect that can vary according to the different development phases. Moreover, the impact may be different if it acts as a substitute to existing rapid transit services. This paper focuses on the impact of substituting bus rapid transit (BRT) for light rail transit (LRT) services, taking into a…

050210 logistics & transportationApartmentbusiness.industryTransit system05 social sciencesAerospace EngineeringTransportationReal estateManagement Science and Operations ResearchEnvironmental economicsAnticipation (artificial intelligence)Public transport0502 economics and businessBusiness Management and Accounting (miscellaneous)Economic impact analysis050207 economicsbusinessExternalityBus rapid transitCivil and Structural EngineeringTransportation Research Part A: Policy and Practice
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Study of J/ψ Production in Jets

2017

The production of $J/\psi$ mesons in jets is studied in the forward region of proton-proton collisions using data collected with the LHCb detector at a center-of-mass energy of 13 TeV. The fraction of the jet transverse momentum carried by the $J/\psi$ meson, $z \equiv p_{\rm T}(J/\psi)/p_{\rm T}({\rm jet})$, is measured using jets with $p_{\rm T}({\rm jet}) > 20$ GeV in the pseudorapidity range $2.5 < \eta({\rm jet}) < 4.0$. The observed $z$ distribution for $J/\psi$ mesons produced in $b$-hadron decays is consistent with expectations. However, the results for prompt $J/\psi$ production do not agree with predictions based on fixed-order non-relativistic QCD. This is the first measurement o…

13000 GeV-cmsQuantum chromodynamics: Experimental testNuclear TheoryGeneral Physics and Astronomy01 natural sciences7. Clean energytransverse momentum [jet]Settore FIS/04 - Fisica Nucleare e SubnucleareHigh Energy Physics - ExperimentParticle production Quantum chromodynamicsddc:550scattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]LHCb - Abteilung HintonParticle productionNuclear ExperimentQuantum chromodynamicsPhysicsJet (fluid)Large Hadron Collider02 Physical SciencesHadron-induced high- and super-high-energy interactions (energy > 10 GeV): Inclusive production with identified hadronParticle physicsQuarkoniumPROMPTJ/psi mesonLeptonic semileptonic and radiative decays of J/ψ Υ and other quarkoniaCERN LHC Collhadroproduction [J/psi(3100)]Pseudorapidityrapidity [jet]root S=7 TEVPhysical SciencesLHCcolliding beams [p p]Particle Physics - ExperimentParticle physicsGeneral PhysicsMesonPSI(2S)Astrophysics::High Energy Astrophysical PhenomenaPhysics Multidisciplinarynonrelativistic [quantum chromodynamics]OCTET QUARKONIA PRODUCTIONNOJets in large-Q2 scatteringNuclear physicsOctet quarkonia production PP collision root S=7 TEV PSI(2S) physics prompt decayPHYSICSPhysics and Astronomy (all)OCTET QUARKONIA PRODUCTION; PP COLLISIONS; ROOT-S=7 TEV; PSI(2S); PHYSICS; PROMPT; DECAY0103 physical sciencesRapiditySDG 7 - Affordable and Clean Energy010306 general physics/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyScience & TechnologyPP COLLISIONSROOT-S=7 TEV010308 nuclear & particles physicsPP collisionhep-exHigh Energy Physics::PhenomenologyLHC-BHEPLHCbHigh Energy Physics::ExperimentHeavy quarkoniaFísica de partículesExperimentsDECAYQuantum chromodynamicsexperimental results
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"Table 11" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"

2022

ZN signal normalized to MB value vs. normalized charged-particle multiplicity in p-p collisions at 13 TeV

13000.0P PZDCVery forward energymidrapidity multiplicity
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"Table 13" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"

2022

ZP signal normalized to MB value vs. normalized charged-particle multiplicity in p-p collisions at 13 TeV

13000.0P PZDCVery forward energymidrapidity multiplicity
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