Search results for "Rays"

showing 10 items of 1136 documents

Assessment of UV Biological Spectral Weighting Functions for Phenolic Metabolites and Growth Responses in Silver Birch Seedlings

2009

In research concerning stratospheric ozone depletion, action spectra are used as biological spectral weighting functions (BSWFs) for describing the effects of UV radiation on plant responses. Our aim was to evaluate the appropriateness of six frequently used BSWFs that differ in effectiveness with increasing wavelength. The evaluation of action spectra was based on calculating the effective UV radiation doses according to 1-2) two formulations of the generalized plant action spectrum, 3) a spectrum for ultraviolet induced erythema in human skin, 4) a spectrum for the accumulation of a flavonol in Mesembryanthemum crystallinum, 5) a spectrum for DNA damage in alfalfa seedlings and 6) the pla…

0106 biological sciencesOzoneUltraviolet Raysmedicine.disease_cause01 natural sciencesBiochemistrySpectral line03 medical and health scienceschemistry.chemical_compoundOzoneFlavonolsPhenolsBotanymedicineFood sciencePhysical and Theoretical ChemistryBetula030304 developmental biologyAction spectrumchemistry.chemical_classification0303 health sciencesbiologyMesembryanthemum crystallinumDose-Response Relationship RadiationGeneral Medicinebiology.organism_classificationOzone depletionchemistrySeedlings13. Climate actionChlorophyllUltraviolet010606 plant biology & botanyPhotochemistry and Photobiology
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The antagonistic effect of UV radiation on warming or nitrate enrichment depends on ecotypes of freshwater macroalgae (Charophytes).

2019

Increases in ultraviolet radiation (UVR), a negative global change factor, affect aquatic primary producers. This effect is expected to be modulated by other global change factors, and to be different for populations adapted to different environments. A common garden experimental approach using freshwater green macroalgae, the cosmopolitan charophyte species Chara hispida and C. vulgaris, allowed us to test whether the beneficial increases in water temperature (T) and nitrate concentration (N) mitigate negative UVR effects. Also, whether these interactions would be not only species-specific but also according to the origin of the population; therefore, two populations of each species were u…

0106 biological sciencesUltraviolet RaysCharophyceaePopulationPlant ScienceAquatic ScienceBiology010603 evolutionary biology01 natural sciencesAcclimatizationchemistry.chemical_compoundNutrientNitratePhotosynthesiseducationLocal adaptationEcotypePhenotypic plasticityeducation.field_of_studyintegumentary systemPrimary producersEcotypeEcology010604 marine biology & hydrobiologyfungiSeaweedchemistryJournal of phycology
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Seasonal fluctuations in leaf phenolic composition under UV manipulations reflect contrasting strategies of alder and birch trees

2010

Seasonal variation in leaf phenolic composition may be important for acclimation of plants to seasonal changes in their biotic and abiotic environment. For a realistic assessment of how plants respond to solar UV-B (280-315 nm) and UV-A (315-400 nm) radiation, seasonal variation in both environment and plant responses needs to be taken into account. This also has implications for studies concerning stratospheric ozone depletion and resulting increased UV-B radiation, as other environmental variables and/or plant phenology could interact with UV radiation. To elucidate this, we established a field experiment using plastic films attenuating different parts of the solar UV spectrum. The concen…

0106 biological sciencesUltraviolet RaysPhysiologyGrowing seasonPlant ScienceAlnus01 natural sciencesAlderTrees03 medical and health sciencesPhenolsBotanyGeneticsBetula030304 developmental biologyAbiotic componentBetulaceae0303 health sciencesAlnus incanabiologyPhenologyCell BiologyGeneral MedicineBetula pubescens15. Life on landbiology.organism_classificationPlant Leaves13. Climate actionSeasons010606 plant biology & botanyWoody plantPhysiologia Plantarum
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Low-Power, Subthreshold Reference Circuits for the Space Environment : Evaluated with -rays, X-rays, Protons and Heavy Ions

2019

The radiation tolerance of subthreshold reference circuits for space microelectronics is presented. The assessment is supported by measured results of total ionization dose and single event transient radiation-induced effects under &gamma

02 engineering and technologyHardware_PERFORMANCEANDRELIABILITYgammasäteily7. Clean energy01 natural sciencesanalog single-event transient (ASET)Ionizationsingle-event effects (SEE)0202 electrical engineering electronic engineering information engineeringAnnan elektroteknik och elektronikElectronic circuitPhysicsprotonsSubthreshold conductionionisoiva säteilyröntgensäteilyGamma raygamma-raysHardware and ArchitectureAtomic physicsVoltage referencemikroelektroniikkaprotonitComputer Networks and Communicationslcsh:TK7800-8360voltage referenceIonheavy-ions0103 physical sciencesionizationradiation hardening by design (RHBD)X-raysHardware_INTEGRATEDCIRCUITSMicroelectronicsElectrical and Electronic Engineeringhiukkassäteilybandgap voltage reference (BGR)Other Electrical Engineering Electronic Engineering Information Engineering010308 nuclear & particles physicsbusiness.industry020208 electrical & electronic engineeringlcsh:Electronicsspace electronicstotal ionization dose (TID)Analog single-event transient (ASET); Bandgap voltage reference (BGR); CMOS analog integrated circuits; Gamma-rays; Heavy-ions; Ionization; Protons; Radiation hardening by design (RHBD); Reference circuits; Single-event effects (SEE); Space electronics; Total ionization dose (TID); Voltage reference; X-raysmikropiiritsäteilyfysiikkaControl and Systems Engineeringreference circuitsSignal ProcessingbusinessSpace environmentHardware_LOGICDESIGNCMOS analog integrated circuits
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UVER and UV index at high altitude in Northwestern Argentina

2016

Measurements of ultraviolet erythemal radiation (UVER) made during two years at three sites located at altitudes over 1000 m a.s.l. in Northwestern Argentina (Salta, San Carlos, and El Rosal) have been used to estimate and analyze the UV Index (UVI) and the cumulative doses at these locations. For the UVER irradiance, data of January (maximum values) and June (minimum values) have been analyzed as representative of the year for all locations. The UVI reaches extreme (> 11) values in > 20% of the analyzed days in Salta (1190 m a.s.l.), while these are reached in San Carlos (1611 m a.s.l.) and El Rosal (3355 m a.s.l.) in > 40% of the analyzed days. Finally, the cumulative doses over an averag…

0301 basic medicine030103 biophysicsVeterinary medicineMeteorologyUltraviolet erythemal radiation (UVER)Ultraviolet RaysBiophysicsIrradianceArgentinaRadiation DosageCumulative dosesCiencias de la Tierra y relacionadas con el Medio Ambiente03 medical and health sciencesRadiation MonitoringHigh altitudeRadiology Nuclear Medicine and imagingSouthern HemisphereRadiationRadiological and Ultrasound TechnologyAltitudeEffects of high altitude on humansUltraviolet index (UVI)Southern hemisphereEnvironmental scienceMeteorología y Ciencias AtmosféricasCIENCIAS NATURALES Y EXACTAS
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Coffee silverskin extract protects against accelerated aging caused by oxidative agents

2016

Nowadays, coffee beans are almost exclusively used for the preparation of the beverage. The sustainability of coffee production can be achieved introducing new applications for the valorization of coffee by-products. Coffee silverskin is the by-product generated during roasting, and because of its powerful antioxidant capacity, coffee silverskin aqueous extract (CSE) may be used for other applications, such as antiaging cosmetics and dermaceutics. This study aims to contribute to the coffee sector’s sustainability through the application of CSE to preserve skin health. Preclinical data regarding the antiaging properties of CSE employing human keratinocytes and Caenorhabditis elegans are col…

0301 basic medicineAgingAntioxidantmedicine.medical_treatmentdermaceuticPharmaceutical ScienceCoffeamedicine.disease_causeAntioxidantsAnalytical Chemistrychemistry.chemical_compound0302 clinical medicineDrug Discoveryoxidative stressFood sciencenutricosmeticCellular SenescenceRoastingChemistryOxidantsChemistry (miscellaneous)030220 oncology & carcinogenesisMolecular Medicinecoffee silverskincoffee silverskin; oxidative stress; UVC radiation; chlorogenic acid; skin health; accelerated aging; nutricosmetic; dermaceuticskin healthCell SurvivalUltraviolet Rayschlorogenic acidOxidative phosphorylationArticlelcsh:QD241-441UVC radiation03 medical and health scienceslcsh:Organic chemistryChlorogenic acidCell Line Tumorparasitic diseasesmedicineaccelerated agingAnimalsHumansPhenolsPhysical and Theoretical ChemistryCaenorhabditis elegansPlant Extractsbusiness.industryOrganic ChemistryAccelerated agingBiotechnologyOxidative StressHaCaT030104 developmental biologyReactive Oxygen SpeciesbusinessBiomarkersOxidative stress
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Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines.

2017

ABSTRACT Glioblastoma multiforme (GBM) exhibits high resistance to the standard treatment of temozolomide (TMZ) combined with radiotherapy, due to its remarkable cell heterogeneity. Accordingly, there is a need to target alternative molecules enhancing specific GBM autocrine or paracrine mechanisms and amplifying the effect of standard treatment. Sphingosine 1-phosphate (S1P) is such a lipid target molecule with an important role in cell invasion and proliferation. Sphingosine kinase inhibitors (SKI) prevent S1P formation and induce increased production of reactive oxygen species (ROS), which may potentiate radiation cytotoxicity. We analyzed the effect of SKI singular versus combined treat…

0301 basic medicineCancer ResearchRadiation-Sensitizing AgentsCell SurvivalCellSphingosine kinaseApoptosistemozolomideBiologyRadiation Tolerancesphingosine kinase inhibition03 medical and health scienceschemistry.chemical_compoundCell Line TumorX-raysmedicineHumansGPx1oxidative stressCytotoxicityAutocrine signallingAntineoplastic Agents AlkylatingPharmacologychemistry.chemical_classificationReactive oxygen speciesTemozolomideSphingosineBrain NeoplasmsDrug SynergismChemoradiotherapyMolecular biologyDacarbazinePhosphotransferases (Alcohol Group Acceptor)030104 developmental biologymedicine.anatomical_structureOncologychemistryCell cultureradiosensitivityCancer researchMolecular MedicineDrug Screening Assays AntitumorGlioblastomamedicine.drugResearch PaperCancer biologytherapy
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Genome-Wide Association Study Identifies New Candidate Markers for Somatic Cells Score in a Local Dairy Sheep

2021

In the Mediterranean basin countries, the dairy sheep production is usually based on local breeds, which are very well-adapted to their production systems and environments and can indeed guarantee income, employment, and economic viability in areas where production alternatives are scarce or non-existent. Mastitis is still one of the greatest problems affecting commercial milk production. However, genetic evaluation of mastitis is particularly difficult because of its low heritability and the categorical nature of the trait. The aim of this study was to identify genomic regions putatively associated with somatic cells count (SCC) in the local economically important Valle del Belice sheep br…

0301 basic medicineCandidate genelcsh:QH426-470PopulationGenome-wide association studyBiologymastitis03 medical and health sciencesSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticomedicineGeneticsGWASlocal dairy sheepUddereducationGenetics (clinical)Genetic associationOriginal Researcheducation.field_of_studybusiness.industry0402 animal and dairy science04 agricultural and veterinary sciencesHeritabilitymedicine.disease040201 dairy & animal scienceBreedMastitisBiotechnologycandidate genes GWAS local dairy sheep mastitis SNPs arrayslcsh:Genetics030104 developmental biologymedicine.anatomical_structureMolecular MedicinebusinessSNPs arrayscandidate genesFrontiers in Genetics
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Network-Wide Adaptive Burst Detection Depicts Neuronal Activity with Improved Accuracy

2017

Neuronal networks are often characterized by their spiking and bursting statistics. Previously, we introducedan adaptive burst analysis methodwhich enhances the analysis power for neuronal networks with highly varying firing dynamics. The adaptation is based on single channels analyzing each element of a network separately. Such kind of analysis was adequate for the assessment of local behavior, where the analysis focuses on the neuronal activity in the vicinity of a single electrode. However, the assessment of the whole network may be hampered, if parts of the network are analyzed using different rules. Here, we test how using multiple channels and measurement time points affect adaptive b…

0301 basic medicineComputer scienceNeuroscience (miscellaneous)Interval (mathematics)Machine learningcomputer.software_genreta3112lcsh:RC321-57103 medical and health sciencesCellular and Molecular NeuroscienceBursting0302 clinical medicineMoving averageHistogramMethodsCluster analysislcsh:Neurosciences. Biological psychiatry. Neuropsychiatryta113network classificationbusiness.industryEmphasis (telecommunications)Pattern recognition217 Medical engineeringlaskennallinen neurotiede113 Computer and information sciencesPower (physics)030104 developmental biologymicroelectrode arraysburst detectionburst synchronySpike (software development)Artificial intelligenceneuronal networksbusinesscomputer030217 neurology & neurosurgeryNeurosciencecomputational neuroscienceFrontiers in Computational Neuroscience
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Longitudinal Analysis of Serum Autoantibody-Reactivities in Patients with Primary Open Angle Glaucoma and Optic Disc Hemorrhage.

2015

Background The aim of our current investigation was to analyze the autoantibody-reactivities of primary open angle glaucoma patients with optic disc hemorrhage as possibly correlated to disease progression by means of a protein microarray approach. Methods Sera of patients with primary open angle glaucoma and optic disc hemorrhage (n = 16) were collected directly after study inclusion (0 weeks) and after 2 weeks, 4 weeks and 12 weeks. As a control group patients with primary open angle glaucoma (n = 18) were used (0 weeks and 12 weeks). Microarrays were incubated and occurring antibody-antigen-reactions were visualized with fluorescence labeled anti-human-IgG secondary antibodies. To detect…

0301 basic medicineMaleRetinal Ganglion CellsSerum ProteinsVisual acuitygenetic structuresEye DiseasesMicroarraysVisionVisual AcuityGlaucomalcsh:MedicineSocial SciencesPathogenesisPathology and Laboratory MedicineVascular MedicineBiochemistryPathogenesis0302 clinical medicineAnimal CellsMedicine and Health SciencesPsychologyLongitudinal Studieslcsh:ScienceNeuronsMultidisciplinarybiologyMiddle AgedPrimary and secondary antibodiesmedicine.anatomical_structureBioassays and Physiological AnalysisDisease ProgressionFemaleSensory PerceptionAntibodymedicine.symptomCellular TypesAnatomyGlaucoma Open-AngleOptic discResearch Articlemedicine.medical_specialtyGanglion CellsOpen angle glaucomaOcular AnatomyProtein Array AnalysisHemorrhageResearch and Analysis MethodsOptic Disc03 medical and health sciencesSigns and SymptomsDiagnostic MedicineOcular SystemOphthalmologymedicineHumansAgedAutoantibodiesbusiness.industrylcsh:RAutoantibodyBiology and Life SciencesAfferent NeuronsProteinsGlaucomaCell Biologymedicine.diseaseeye diseasesOphthalmology030104 developmental biologyCellular Neuroscience030221 ophthalmology & optometrybiology.proteinlcsh:Qsense organsbusinessNeurosciencePloS one
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