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Commentary: Preliminary Evidence for Training-Induced Changes of Morphology and Phantom Limb Pain

2019

The aim of this study was to investigate whether a special prosthetic training in phantom limb pain patients aimed at increasing the functional use of the prosthesis leads to neural morphological plasticity of brain structures and a reduction in phantom limb pain. For chronic pain disorders, it was shown that morphological alterations due to pain might become at least partially reversed by pain therapies. Phantom limb pain is a chronic pain disorder that is frequently followed by neural plasticity of anatomical brain structures. In our study, 10 patients with amputation of the upper limb participated in a two-week training with a myoelectric prosthesis with somatosensory feedback. Grip stre…

medicine.medical_specialtyvisiontactile feedbackPhantom limb painlcsh:RC321-571Behavioral NeurosciencePhysical medicine and rehabilitationsomatosensory feedbackMedicinepassive stimulationactive traininglcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatryvirtual reality (VR)Original Researchphantom limb pain (PLP)business.industrygray matterupper limb amputationbody regionsPsychiatry and Mental healthNeuropsychology and Physiological PsychologyNeurologyplasticityprosthesisbusinessNeuroscienceFrontiers in Human Neuroscience
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Differences in cytomegalovirus plasma viral loads measured in allogeneic hematopoietic stem cell transplant recipients using two commercial real-time…

2010

5 páginas, 3 figuras.

medicine.medical_treatmentCongenital cytomegalovirus infectionCytomegalovirusHematopoietic stem cell transplantationHematopoietic stem cell transplantationBiologyPolymerase Chain ReactionAutomationPlasmaVirologymedicineHumansViral loadHematopoietic Stem Cell Transplantationvirus diseasesViral LoadUniversity hospitalmedicine.diseaseVirologyDNA extractionAllogeneic stem cell transplantReverse transcription polymerase chain reactionInfectious DiseasesReal-time polymerase chain reactionSpainImmunologyCytomegalovirus InfectionsAllogeneic hematopoietic stem cell transplantViral loadReal-time PCRJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology
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Optimized culture conditions for tissue explants of uterine leiomyoma

2012

Background Uterine leiomyomas are the most common benign tumours in women, which arise from smooth muscle cells of the uterine myometrium and usually are multicentric. In spite of their frequency pathogenesis is widely unknown, mainly due to the absence of a suitable model system. We describe the systematic optimization of culturing leiomyoma tissue explants in an economical and effective ex vivo system. Methods Different concentrations of oxygen, different media, sera, hormones, and growth factor supplements were tested. Immunohistochemical stainings with antibodies against hormone receptors as well as specifying proliferation and apoptotic indices and real-time PCR were performed. Results…

medicine.medical_treatmentCulture Media; Epidermal Growth Factor; Estradiol; Female; Humans; Immunohistochemistry; Leiomyoma; Progesterone; RNA Messenger; Real-Time Polymerase Chain Reaction; Uterine NeoplasmsBiologyReal-Time Polymerase Chain ReactionGeneral Biochemistry Genetics and Molecular BiologyAndrologyTissue culturemedicineHumansRNA MessengerUterine NeoplasmProgesteroneUterine leiomyomaEpidermal Growth FactorEstradiolLeiomyomaGrowth factorMyometriummedicine.diseaseImmunohistochemistrySettore MED/40 - Ginecologia E OstetriciaCulture MediaLeiomyomaHormone receptorUterine NeoplasmsFemaleEx vivoHuman
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Guillain-Barré syndrome after orthotopic liver transplantation: A clinical manifestation of immune reconstitution inflammatory syndrome?

2018

Guillain-Barrè Syndrome, as part of the spectrum of dysimmune neuropathies, is unexpected to occur in immunocompromised hosts. We describe a clinical case of Guillain-Barrè syndrome, occurred a few weeks after a liver transplant, and we postulate that our case would satisfy all requirements to explain this peripheral nervous system complication as a clinical manifestation of an Immune reconstitution inflammatory syndrome. In this setting of liver transplantation, complicated by potentially multiple infective triggers, reduction of immunosuppression and reversal of pathogen-induced immunosuppression, through antimicrobial therapy, may have led to pro-inflammatory response. The pro-inflammato…

medicine.medical_treatmentLiver transplantationGuillain-Barre SyndromeTacrolimus030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineImmune systemImmune reconstitution inflammatory syndromemedicineHumansImmune reconstitution inflammatory syndromeAcute demyelinating polyneuropathyImmunosuppression TherapyInflammationLiver transplantationGuillain-Barre syndromebusiness.industryImmunosuppressionGeneral Medicinemedicine.diseaseGuillain-Barré syndromeTacrolimusPathophysiologyTacrolimuImmunologyAcute demyelinating polyneuropathy; Guillain-Barré syndrome; Immune reconstitution inflammatory syndrome; Liver transplantation; TacrolimusSurgeryFemaleNeurology (clinical)Complicationbusiness030217 neurology & neurosurgery
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Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Sin…

2021

Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the rescue treatment proposed to patients with refractory cardiogenic shock. The VA-ECMO implantation promotes inflammation and ischemia-reperfusion injuries through the VA-ECMO flow, causing digestive mucosa barrier disrupture and inducing translocation of bacterial wall components—Lipopolysaccharides (LPS) with further inflammation and circulatory impairment. LPS is a well-studied surrogate indicator of bacterial translocation. Oxiris membrane is a promising and well-tolerated device that can specifically remove LPS. The main study aim is to compare the LPS elimination capacity of Oxiris membrane vs. a non-absorban…

medicine.medical_treatmentcontinuous renal replacement therapyheart failureoxirisContext (language use)InflammationCardiovascular Medicineartificial membranelaw.inventionStudy ProtocolRandomized controlled triallawmedicineClinical endpointExtracorporeal membrane oxygenationDiseases of the circulatory (Cardiovascular) systemRenal replacement therapycytokines/bloodbusiness.industryCardiogenic shockcardiogenic shockextracorporeal membrane oxygenationmedicine.diseasesurgical procedures operativeendotoxin/bloodRC666-701AnesthesiaHeart failuremedicine.symptomCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
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Pharmacokinetics of new oral anticoagulants: implications for use in routine care

2018

Introduction: Since 2008, new oral anticoagulants (NOACs) have been approved for the prevention of venous thromboembolism (VTE) in patients receiving hip or knee replacement surgery, prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF), treatment of deep vein thrombosis (DVT), and pulmonary embolism (PE). Premarketing randomized clinical trials (RCTs) of NOACs demonstrated their non-inferiority in terms of efficacy vs. warfarin (traditional oral anticoagulant–TOA), with lower risk of serious adverse drug reactions, especially cerebral hemorrhages. In clinical practice, pharmacokinetic aspects of NOACs have to be carefully taken into account to …

medicine.medical_treatmentnew oral anticoagulantsAdministration OralKnee replacement030204 cardiovascular system & hematologyToxicologyAdherence Bleeding Interactions New oral anticoagulants Over- and under-dosage Persistence Pharmacokinetics Real World Evidence0302 clinical medicineAtrial Fibrillationover- and underdosage030212 general & internal medicinepharmacokineticStrokeRoutine careRandomized Controlled Trials as Topicnew oral anticoagulantAtrial fibrillationpersistenceVenous ThromboembolismGeneral MedicinePulmonary embolismStrokepharmacokineticsHumanmusculoskeletal diseasesmedicine.medical_specialtyinteractionHemorrhageMedication Adherence03 medical and health sciencesPharmacokineticsmedicineHumansReal World EvidenceIn patientOver- and under-dosagecardiovascular diseasesreal-world evidenceIntensive care medicineAgedPharmacologybusiness.industryAnticoagulantAnticoagulantsinteractionsbleedingmedicine.diseaseAdherencePulmonary EmbolismbusinessVenous thromboembolismExpert Opinion on Drug Metabolism & Toxicology
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Realitātes šova “Saimnieks meklē sievu” dalībnieku popularitāte pēc dalības šovā: Magones Šutovienes gadījums

2022

Bakalaura darba tēma ir realitātes šova “Saimnieks meklē sievu” dalībnieku popularitāte pēc dalības šovā: Magones Šutovienes gadījums. Darba mērķis ir analizēt Magones Šutovienes popularitāti medijos, balstoties uz viņas publicitāti ziņu portālos laika posmā no 2013.gada 1.oktobra līdz 2021. gada 31. decembrim. Pētījuma problēma ir realitātes šova “Saimnieks meklē sievu” dalībnieces Magones Šutovienes popularitāts iemesli interneta medijos vairāku gadu garumā pēc dalības šovā. Galvenā teorētiskā bāze ir televīzijas, realitātes šovu, dzeltenās preses mediju darbības pamatprincipi. Teorētiskajā daļā tiek pielietotas arī komunikācijas teorijas- kultivācijas teorija un sociāli kognitīvā teorija…

medijirealitātes šovs "Saimnieks meklē sievu"realitātes televīzijaKomunikācijas zinātnetelevīzijaslava
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Rumor de pañuelo blanco: historia, memoria y representaciones literarias de Abuelas de Plaza de Mayo

2018

El 24 de marzo de 2016 se cumplieron 40 años del golpe de Estado del autodenominado Proceso de Reorganización Nacional que condujo a siete años de una sangrienta dictadura en Argentina. De entre las organizaciones de Derechos Humanos que surgieron como respuesta a las desapariciones ilegales de militantes y de civiles, las Madres y Abuelas de Plaza de Mayo se han constituido, tanto a nivel nacional como internacional, en evidencia de la historia de violencia y en símbolo de paz; como tales también han entrado en el plano de la ficción. Teniendo en cuenta estas líneas, en el presente trabajo se realiza, primero, un recorrido por la historia de las Abuelas de Plaza de Mayo y el cambio polític…

memoriaHistoryLiterature and Literary TheoryHuman rightsmedia_common.quotation_subjectDictadura argentinaDictatorship ArgentinaliteraturaDictatorshipGrandmothers of Plaza de MayoSymbolLiteratureMemoryRealmAbuelas de Plaza de MayoHumanitiesmedia_common
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Salesperson adoption and usage of mobile sales configuration tools

2018

PurposeThe purpose of this paper is to examine salespersons’ adoption and usage of mobile sales configuration tools (MSCT) and to identify areas for further development in this realm. Another objective is to offer a conceptualization of MSCT adoption.Design/methodology/approachFor this purpose, a qualitative case study approach was selected as the research method to better understand acceptance of a mobile configuration tool used by business-to-business (B2B) salespersons. Primary data were collected through semi-structured interviews, which included a series of open-ended questions to gain more detailed and contextual data.FindingsThe results obtained from the interviews indicated several …

menekkiFuture studiesKnowledge managementGeneral Computer ScienceComputer sciencemyyntimobiilimarkkinointisales force automation0502 economics and businessRealmSocial mediaB2B salesResearch methodSocial desirabilityyritysmyyntiConceptualizationbusiness.industry05 social sciencesmobliililaitteetmobile sales adoptionSales force automationQuantitative analysis (finance)qualitativeion tools050211 marketingbusiness050203 business & managementInformation SystemsJournal of Systems and Information Technology
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Traduzione di J. R. Searle, Che cos'è il linguaggio. Alcune osservazioni preliminari.

2008

In questo saggio John Searle propone una concezione naturalizzata del linguaggio e dei rapporti tra linguaggio e realtà sociale. Mostra, più specificamente, come il linguaggio si sviluppi a partire da stati mentali prelinguistici quali le intenzioni, le credenze e i desideri, attraverso l'imposizione di condizioni di soddisfazione su condizioni di soddisfazione. Mostra, inoltre, come il linguaggio, rendendo possibili gli impegni deontici e le ragioni per l'azione indipendenti dal desiderio che caratterizzano la razionalità umana, sia parzialmente costitutivo della realtà istituzionale.

mente intenzionalità coscienza linguaggio impegni deontici realtà istituzionale.
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