Search results for "Refractive errors"

showing 10 items of 57 documents

Performance of the compensation comparison method for retinal straylight measurement: effect of patient's age on repeatability

2008

Aim: The assessment of repeatability and reproducibility of retinal straylight measurements with the C-Quant straylight meter (Oculus AG, Germany) and the effect of patient’s age on the instrument performance are tested with a series of experiments. Methods: First, 20 eyes from 20 subjects (mean age 26.9 (SD 2.7) years, mean refractive error −1.34 (2.72) D) were examined with the C-Quant straylightmeter, taking 10 consecutive readings. Five subjects were also examined on five consecutive days to assess reproducibility. Additionally, repeated measures of straylight from 84 subjects of ages ranging from 19 to 86 years (mean (SD): 42.4 (24.0) years) were retrospectively analysed to assess the …

AdultMalemedicine.medical_specialtyRefractive errorPsychometricsRetinaCellular and Molecular Neurosciencechemistry.chemical_compoundOphthalmologymedicineHumansScattering RadiationAgedAged 80 and overAnalysis of VarianceReproducibilitybusiness.industryOphthalmoscopesAge FactorsRepeated measures designRetinalMean ageRepeatabilityMiddle AgedRefractive Errorsmedicine.diseaseSensory SystemsOphthalmoscopyOphthalmologychemistryOptometryFemalebusinessBritish Journal of Ophthalmology
researchProduct

Association of low birth weight with myopic refractive error and lower visual acuity in adulthood: results from the population-based Gutenberg Health…

2017

PurposeLow birth weight (BW) is linked to impaired organ development in childhood, including altered ocular morphological and functional development. The aim of this study was to evaluate whether low BW has long-term effects on visual acuity and refraction in adulthood.MethodsThe Gutenberg Health Study is a population-based, observational cohort study in Germany, including 15 010 participants aged between 35 and 74 years. These participants were divided into three different BW groups (low: <2500 g; normal: between 2500 and 4000 g; and high: >4000 g). Best-corrected visual acuity and objective refraction were examined. We used multivariable linear regression models with adjustment for …

AdultMalemedicine.medical_specialtyRefractive errorVisual acuitygenetic structuresBirth weightVisual AcuityAstigmatismCohort Studies03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineOphthalmologyGermanymedicineMyopiaHumansProspective StudiesDioptreAgedbusiness.industryInfant NewbornMacular degenerationInfant Low Birth WeightMiddle Agedmedicine.diseaseRefractive ErrorsSensory SystemsOphthalmologyLow birth weightLogistic Models030221 ophthalmology & optometryFemalemedicine.symptombusiness030217 neurology & neurosurgeryCohort studyThe British journal of ophthalmology
researchProduct

Prevalence of refractive errors in the European adult population: the Gutenberg Health Study (GHS).

2014

Objective To study the distribution of refractive errors among adults of European descent. Design Population-based eye study in Germany with15 010 participants aged 35–74 years. Methods The study participants underwent a detailed ophthalmic examination according to a standardised protocol. Refractive error was determined by an automatic refraction device (Humphrey HARK 599) without cycloplegia. Definitions for the analysis were myopia +0.5 D, astigmatism >0.5 cylinder D and anisometropia >1.0 D difference in the spherical equivalent between the eyes. Exclusion criterion was previous cataract or refractive surgery. Results 13 959 subjects were eligible. Refractive errors ranged from −21.5 to…

AdultMalemedicine.medical_specialtyRefractive errorgenetic structuresmedicine.medical_treatmentPopulationVisual AcuityAstigmatismWhite PeopleCellular and Molecular NeuroscienceAge DistributionRefractive surgeryOphthalmologyGermanymedicinePrevalenceHumansVision testProspective StudiesSex DistributioneducationRetinoscopyAnisometropiaAgededucation.field_of_studymedicine.diagnostic_testbusiness.industryVision TestsCycloplegiaMiddle Agedmedicine.diseaseRefractive ErrorsHealth Surveyseye diseasesSensory SystemsOphthalmologyOptometryFemalemedicine.symptombusinessRetinoscopyThe British journal of ophthalmology
researchProduct

Vision evaluation in people with Down's syndrome.

1994

We tested the colour vision of 72 people with Down's syndrome using the Ishihara test and an anomaloscope. We found that 13 of the subjects, 6 males and 7 females, had defective colour vision according to Pickford's classification. In monocular vision 10 eyes were protan (five simple, three extreme and two deviant), one eye was simple deuteranomalous and the remaining eyes were normal: in binocular vision four of the subjects were protan (two simple and two deviant), two subjects were deutan (one simple and one deviant) and the rest were normal. Many of our subjects had lens opacities, strabismus, nystagmus, hypermetropia, high myopia and astigmatism, confirming literature reports. The cont…

AdultMalemedicine.medical_specialtygenetic structuresAdolescentColor visionColor Vision DefectsNystagmusAstigmatismAudiologyCataractNystagmus PathologicDevelopmental psychologyVision disorderContrast SensitivityVision MonocularmedicineHumansStrabismusChildVision Binocularmedicine.diseaseRefractive Errorseye diseasesSensory SystemsAnomaloscopeStrabismusOphthalmologyFemalemedicine.symptomDown SyndromePsychologyBinocular visionMonocular visionOptometryOphthalmicphysiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
researchProduct

Effect of 3rd-order aberrations on human vision

2007

To investigate the effect of 3rd-order aberrations on human vision.Grupo de Ciencias de la Visión, University of Murcia, Murcia, Spain.The 3rd-order aberrations coma and trefoil were induced with purpose-designed soft contact lenses, 3 inducing coma (low [0.05 microm], medium [0.13 microm], high [1.03 microm]) and 3 inducing trefoil (low [0.07 microm], medium [0.17 microm], high [0.96 microm]). Monocular high-contrast (HCVA) and low-contrast (LCVA) visual acuities and contrast sensitivity were measured in 11 subjects wearing contact lenses with a 5.0 mm artificial pupil.The reduction in HCVA and LCVA was statistically significant only for the highest coma and trefoil values (P.0001). For co…

AdultMalemedicine.medical_specialtygenetic structuresmedia_common.quotation_subjectmedicine.medical_treatmentVision DisordersVisual AcuityComa (optics)Models Biologicaldigestive systemContrast SensitivityOcular physiologyOpticsOphthalmologyRefractive surgeryHumansMedicineContrast (vision)TrefoilVision Ocularmedia_commonbusiness.industryContact Lenses HydrophilicRefractive ErrorsSensory SystemsInduced comaOphthalmologyFemaleSurgerybusinessJournal of Cataract and Refractive Surgery
researchProduct

The effect of spherical aberration on visual performance and refractive state for stimuli and tasks typical of night viewing

2018

Purpose: The aim of this work was to examine the impact of Seidel spherical aberration (SA) on optimum refractive state for detecting and discriminating small bright lights on a dark background. Methods: An adaptive-optics system was used to correct ocular aberrations of cyclopleged eyes and then systematically introduce five levels of Seidel SA for a 7-mm diameter pupil: 0, ± 0.18, and ± 0.36 diopters (D) mm−2. For each level of SA, subjects were required to detect one or resolve two points of light (0.54 arc min diameter) on a dark background. Refractive error was measured by adjusting stimulus vergence to minimize detection and resolution thresholds. Two other novel focusing tasks for si…

AdultOptics and PhotonicsOriginal articleCorneal Wavefront AberrationVisual AcuityStarburstDiameter pupilRefraction Ocular050105 experimental psychology03 medical and health sciences0302 clinical medicinelcsh:OphthalmologyError refractivoVisión nocturnaAberración esféricalcsh:QC350-467Humans0501 psychology and cognitive sciencesSpherical aberrationNight visionPhysicsResoluciónRefractive error05 social sciencesMiddle AgedRefractive ErrorsDetecciónDetectionlcsh:RE1-994030221 ophthalmology & optometryResolutionHumanitieslcsh:Optics. LightPhotic StimulationOptometryJournal of Optometry
researchProduct

OCT for Assessing Artificial Tears Effectiveness in Contact Lens Wearers

2011

PURPOSE: To apply a commercially available high-resolution spectral domain optical coherence tomographer (SOCT) to assess the change in tear volume after application of a new artificial tears formulation specifically developed for contact lens (CL) users. METHODS: Twenty OD from young healthy CL wearers (mean age, 24.7 ± 3.5 years) with refractive errors ranging from -0.75 to -2.50 D (mean, -1.56 ± 0.69 D) were examined. All subjects were fitted with Focus Dailies CL (Ciba Vision), and two drops of Blink Contacts (AMO), lubricating formulation specifically developed for CL wearers, were instilled after baseline measures. Tear meniscus volume (TMV) was measured immediately after and 1 min, 1…

Adultmedicine.medical_specialtyContact Lensesmedicine.medical_treatmentMeniscus (anatomy)Tear volumeYoung AdultRegular distributionOphthalmologyImage Processing Computer-AssistedHumansMedicinebusiness.industryRepeated measures designContact Lenses HydrophilicRefractive ErrorsContact lensOphthalmologyArtificial tearsmedicine.anatomical_structureTear meniscusOftalmologíaDry Eye SyndromesEyelidOphthalmic SolutionsbusinessTomography Optical CoherenceFollow-Up StudiesOptometryOptometry and Vision Science
researchProduct

The effect of simulated normal and amblyopic higher-order aberrations on visual performance.

2012

Purpose To study the effect of simulated amblyopic and normal higher-order aberrations on visual performance of normal eyes. Methods To assess visual function, an adaptive optics visual simulator was used to compensate volunteers' ocular aberrations and simulate the wavefront aberration patterns found in healthy and amblyopic eyes in 7 healthy individuals. Visual acuity for high (100%), medium (50%), and low (10%) contrast and contrast sensitivity at 10, 20, and 25 cycles per degree (cpd) were measured after simulation of both pattern aberrations. The modulation transfer function and the point spread function were computed based on the aberration data. All measures were taken for 3 and 5.5 …

Adultmedicine.medical_specialtyVisual acuityCorneal Wavefront Aberrationgenetic structuresmedia_common.quotation_subjectVisual AcuityAmblyopiaPupilContrast SensitivityYoung AdultOphthalmologyOptical transfer functionmedicineContrast (vision)Humansmedia_commonContrast levelbusiness.industryAberrometryPupil sizeAstigmatismPupilModels TheoreticalRefractive Errorseye diseasesOphthalmologyAberrations of the eyePediatrics Perinatology and Child HealthOptometrysense organsSpatial frequencymedicine.symptombusinessJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
researchProduct

Contrast sensitivity after LASIK flap creation with a femtosecond laser and a mechanical microkeratome

2007

ABSTRACT PURPOSE: To compare the effects on contrast sensitivity of the IntraLase femtosecond laser for flap creation (IntraLASIK) and standard LASIK for myopia. METHODS: Two hundred eyes of 100 consecutive patients underwent LASIK treatment using the VISX S2 laser system. The femtosecond laser (15 kHz IntraLase) was used for flap creation in 100 eyes (50 patients) and a mechanical microkeratome (Carriazo-Barraquer) was used in 100 eyes (50 patients). Best spectacle-corrected contrast sensitivity was measured before and 6 months postoperatively in the IntraLASIK and mechanical LASIK groups. The IntraLASIK and mechanical LASIKinduced changes in contrast sensitivity were compared under photop…

Adultmedicine.medical_specialtygenetic structuresMesopic visionmedicine.medical_treatmentmedia_common.quotation_subjectKeratomileusis Laser In SituSurgical Flapslaw.inventionContrast SensitivitylawMicrokeratomeOphthalmologymedicineHumansContrast (vision)media_commonbusiness.industryLASIKEquipment DesignRefractive ErrorsLasereye diseasesRefractive Surgical ProceduresSurgeryOphthalmologyTreatment OutcomeFemtosecondSurgerysense organsbusinessSensitivity (electronics)Follow-Up StudiesPhotopic vision
researchProduct

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

2013

Author version made available in accordance with the publisher's policy.

Candidate geneRefractive errorBone Morphogenetic Protein 2Genome-wide association studyVARIANTSGenomeGenome-wide association studies0302 clinical medicineRisk FactorsMyopiaGRIA4Genetics0303 health sciencesKCNQ Potassium ChannelsDisease geneticsEYE GROWTHASSOCIATIONRETINAL-PIGMENT EPITHELIUMRefractive ErrorsGenetic load3. Good healthADAPTED MOUSE RETINAMeta-analysisACIDPOTASSIUM CHANNELEXPRESSIONSingle-nucleotide polymorphismBiologyWhite PeopleArticle03 medical and health sciencesAsian PeoplemedicineGeneticsHumansGenetic Predisposition to DiseaseReceptors AMPAgene; myopia; refractive030304 developmental biologyHomeodomain Proteinsta1184ta3121medicine.diseaseGENEAlcohol OxidoreductasesSERINE-PROTEASEbiology.protein030221 ophthalmology & optometrySusceptibility locusTrans-ActivatorsEye disorderLamininSerine ProteasesGWAS; meta-analyses; refractive error; myopiaGenome-Wide Association StudyNature Genetics
researchProduct