Search results for "Region"

showing 10 items of 4910 documents

Sequence of a sea urchin hsp70 gene and its 5' flanking region.

1990

We report the nucleotide sequence of a 4470-bp fragment derived from a sea urchin genomic clone containing part of a heat-shock protein 70 (Hsp70)-encoding gene. This fragment, named hsp70 gene II, contains 1271 bp of the flanking region and 3299 bp of structural gene sequence interrupted by five introns and encoding the N-terminal 371 amino acids (aa) of the protein. The 5' flanking region contains a putative TATA element, two CCAAT boxes, four heat-shock consensus sequence elements (hse) and one consensus sequence for binding of Sp1. Remarkable homologies were observed for deduced aa sequence and intron-exon organization between hsp70 gene II and rat hsc73 gene.

5' flanking regionMolecular Sequence DataRestriction MappingBiologyExonSequence Homology Nucleic AcidConsensus SequenceGeneticsConsensus sequenceAnimalsAmino Acid SequencePromoter Regions GeneticGenePeptide sequenceHeat-Shock ProteinsGeneticsBase SequenceStructural geneNucleic acid sequenceGeneral MedicineExonsMolecular biologyIntronsGenesRegulatory sequenceSea UrchinsGene
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5-Fluororacile-loaded matrix tablets for locoregional delivery: effects on a three-dimensional culture model of primary oral squamous cell carcinoma

2012

5-Fluorouracil Locoregional drug delivery Oral squamous cell carcinoma Buccal tablets 3D oral outgrowths
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Innovation Policies for Regional Structural Change: Combining Actor-Based and System-Based Strategies

2018

This chapter analyses opportunities and challenges for regional innovation policies designed to promote new path development in different types of regional innovation systems (RISs). RISs differ enormously in their capacity to develop new growth paths due to pronounced differences in endogenous potentials and varying abilities to attract and absorb exogenous sources for new path development. We distinguish between different types of regional industrial path development, which reflect various degrees of radicalness of regional structural change. The chapter offers a conceptual analysis of conditions and influences that enable and constrain new path development in different types of RISs and …

507023 Standortentwicklung502039 Structural policy507023 Location development502039 Strukturpolitik05 social sciences0211 other engineering and technologies0507 social and economic geography021107 urban & regional planning02 engineering and technology502014 Innovation research507014 Regionalentwicklung507016 RegionalökonomieGeography507011 Raumforschung507011 Spatial research507014 Regional development507507016 Regional economyOperations management502014 Innovationsforschung050703 geographyIndustrial organizationEconomic change
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The evolution of Military Health in Valencia during the Spanish Civil War (1936-1939)

2011

Antecedentes y objetivos: Tras la insurrección militar del 18 de julio de 1936 el Ejército de la República quedó parcialmente desarticulado, resultando afectada la Sanidad Militar. En el caso de Valencia, ésta fue asumida rápidamente por el Comité Sanitario Popular, un organismo revolucionario que lideró la respuesta sanitaria de Valencia a la Guerra Civil. Posteriormente, el Gobierno Republicano procedió a recuperar el poder a través de medidas de carácter centralizador, como fue la militarización de algunos hospitales. Fue entonces cuando volvió a articularse una auténtica Sanidad Militar. El objetivo de este trabajo es estudiar la evolución de la Sanidad Militar en Valencia, una de las z…

5506.17 Historia de la MedicinaGeneral EngineeringSanidad militarMilitarizationMilitarizaciónMilitary HealthMilicianos5503.02 Historia RegionalSpanish Civil WarMilitiamenGuerra Civil españolaGeneral Earth and Planetary Sciences5103.05 GuerraGeneral Environmental Science
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Health coverage for a retreating army: a Medical Captain’s action during the Maestrazgo campaign (April-July 1938).

2012

espanolAntecedentes y objetivos: Tras la entrada definitiva de las tropas del general Franco en la ciudad de Teruel en febrero de 1938 se inicio la retirada progresiva del Ejercito de Maniobra de la republica. El rapido avance de las fuerzas nacionales hacia el Mediterraneo marco las caracteristicas de la cobertura sanitaria militar. El objetivo de este trabajo es realizar una aproximacion a la Sanidad del Ejercito republicano durante su retirada por el Maestrazgo castellonense, que tuvo lugar entre abril y julio de 1938 en el contexto de la Guerra Civil Espanola (1936-1939). Material y metodos: Hemos utilizado una fuente de gran valor historico, como es el testimonio oral de un Capitan Med…

5506.17 Historia de la MedicinaMilitary Health CareGeneral EngineeringSanidad militarMaestrazgo Battle5503.02 Historia RegionalBatalla del MaestrazgoSpanish Civil WarGuerra Civil españolaGeneral Earth and Planetary SciencesRetreating army5103.05 GuerraEjército en retiradaGeneral Environmental ScienceSanidad Militar
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Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae

2013

Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox cofactor in a wide variety of biological processes. Recent studies in Saccharomyces cerevisiae have shown that in response to iron deficiency, an RNA-binding protein denoted Cth2 coordinates a global metabolic rearrangement that aims to optimize iron utilization. The Cth2 protein contains two Cx8Cx5Cx3H tandem zinc fingers (TZFs) that specifically bind to adenosine/uridine-rich elements within the 3' untranslated region of many mRNAs to promote their degradation. The Cth2 protein shuttles between the nucleus and the cytoplasm. Once inside the nucleus, Cth2 binds target mRNAs and stimulate…

572 Biochemistryalternative 3' end processingSaccharomyces cerevisiae ProteinsIronTristetraprolinSaccharomyces cerevisiaeSaccharomyces cerevisiaeReviewyeastCatalysisInorganic Chemistrylcsh:ChemistryCth1TristetraprolinmRNA decayGene Expression Regulation FungalCth2medicineRNA MessengerRnt1Physical and Theoretical Chemistry3' Untranslated RegionsMolecular BiologyTranscription factorlcsh:QH301-705.5SpectroscopyMessenger RNAalternative 3′ end processingbiologyThree prime untranslated regionOrganic ChemistryQR MicrobiologyGeneral MedicineIron deficiencymedicine.diseasebiology.organism_classificationComputer Science ApplicationsDNA-Binding ProteinsRibonucleotide reductaseBiochemistrylcsh:Biology (General)lcsh:QD1-999Cytoplasmalternative 3' end processingTranscription Factorspost-transcriptional regulationInternational Journal of Molecular Sciences
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Extent and persistence of soil water repellency induced by pines in different geographic regions

2018

The extent (determined by the repellency indices RI and RIc) and persistence (determined by the water drop penetration time, WDPT) of soil water repellency (SWR) induced by pines were assessed in vastly different geographic regions. The actual SWR characteristics were estimated in situ in clay loam soil at Ciavolo, Italy (CiF), sandy soil at Culbin, United Kingdom (CuF), silty clay soil at Javea, Spain (JaF), and sandy soil at Sekule, Slovakia (SeF). For Culbin soil, the potential SWR characteristics were also determined after oven-drying at 60°C (CuD). For two of the three pine species considered, strong (Pinus pinaster at CiF) and severe (Pinus sylvestris at CuD and SeF) SWR conditions we…

631 - Agricultura. Agronomía. Maquinaria agrícola. Suelos. Edafología agrícola0208 environmental biotechnologyRepellency indexSoil science02 engineering and technologySoilSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliClay soilWater Science and TechnologyFluid Flow and Transfer Processesrepellency indexbiologyMechanical EngineeringHydraulic engineering04 agricultural and veterinary sciencesbiology.organism_classificationPine020801 environmental engineeringRepellency index.Water repellencyLoamSoil water040103 agronomy & agricultureGeographic regions0401 agriculture forestry and fisheriesEnvironmental sciencePinus pinasterTC1-978Water drop penetration time
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Thermomineral waters of Greece: geochemical characterization

2020

75 °C). In terms of pH most results vary from 5.5 to 823 °C) ii) warm (23 40 °C) iii) thermal (40 75 °C) and iv) hyperthermal (&gtfew springs show either very low pH (&lt10) proposing serpentinization processes. Regarding TDS concentrations collected waters can be subdivided into low salinity (up to 1.5 g/L) brackish (up to 20 g/L) and saline (up to 43 g/L). The medium high salinities can be justified by mixing with sea water and/or strong waterrock interaction processes. Isotope composition of O and H ranges from 12.7 to +2.7 ‰ SMOW and from 91 to +12 ‰ SMOW respectively and is generally comprised between the Global Meteoric Water Line and the East Mediterranean Meteoric Water Line. Only few water samples show a positive shift for δ18O possibly related to high temperature waterrock interaction processes. Carbon dioxide (18 997000 μmol/mol) or N2 (1100 989000 μmol/mol) or CH4 (&ltMany geothermal areas of Greece are located in regions affected by Miocene or Quaternary volcanism and in continental basins characterised by elevated heat flow. Moreover the majority of them is found along the coast as well as in islands of the Aegean Sea and thus thermal water is often brackish to saline due to marine intrusion into costal aquifer. In the present study almost 300 thermal and cold mineral water samples were collected along the Hellenic territory with their physicochemical parameters (temperature pH electrical conductivity and Eh) and the amount of bicarbonates (titration with 0.1N HCl) being determined in situ. Additionally gases found either in free or dissolved phase were sampled. Both water and gas samples were analysed at the INGVPa laboratories for major ions (Ion Chromatography) silica (Inductively Coupled Plasma Optical Emission Spectrometry) chemical composition of free and dissolved gases (Gas Chromatography) water isotopes (O and H) and carbon and helium isotopes of free and dissolved gases (Mass Spectrometry). The temperature of the investigated waters ranges from 6.5 to 98°C pH from 1.96 to 11.98 whilst Total Dissolved Solids (TDS) from 0.06 to 43 g/L. Based on the temperature parameter waters can be divided into four groups: i) cold (&lt0.5 913000 μmol/mol) are the prevailing gas species found in the studied sites. The δ13CCO2 values ranged from 20.1 to +8.5 ‰ whilst the isotope ratio of He from 0.21 to 6.71 R/RA.4) suggesting interaction with H2Srich gases or very high pH values (&gtSettore GEO/08 - Geochimica E Vulcanologia
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"Table 7" of "Measurement of the differential cross-section of highly boosted top quarks as a function of their transverse momentum in $\sqrt{s}$ = 8…

2016

Correlation matrix between the bins of the particle-level differential cross-section as a function of $p_{T,ptcl}$.

8000.0educationfood and beveragesTopAstrophysics::Cosmology and Extragalactic AstrophysicsPhysics::Data Analysis; Statistics and ProbabilityP P --> TOP TOPBAR Xbody regionsInclusiveSingle Differential Cross SectionProton-Proton Scatteringnatural sciencesDSIG/DPTTransverse Momentum Dependence
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Combined Innovation Policy: Linking Scientific and Practical Knowledge in Innovation Systems

2012

New research indicates that firms combining the science-based STI (Science, Technology, Innovation) and the experience-based DUI (Doing, Using, Interacting) modes of innovation are more efficient when it comes to improving innovation capacity and competitiveness. With regard to innovation policy, the STI mode calls for a supply driven policy, typically aimed to commercialise research results. The DUI mode suggests a demand driven policy approach, such as supporting the development of new products or services to specific markets. This paper analyses how the two types of innovation policy and the two innovation modes can be combined in regional innovation systems. The analysis builds on studi…

9. Industry and infrastructure05 social sciencesGeography Planning and Development0211 other engineering and technologiesInnovation management021107 urban & regional planning02 engineering and technologyPolicy initiativesInnovation policy Regional system of innovation Modes of innovation Food industry Agribusiness Farm Management Food Consumption/Nutrition/Food Safety Industrial Organization Research Methods/ Statistical Methods0502 economics and businessEconomicsMarketing050203 business & managementIndustrial organizationAgribusiness
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