Search results for "Regular"

showing 10 items of 855 documents

Evaluation of MRI and cannabinoid type 1 receptor PET templates constructed using DARTEL for spatial normalization of rat brains

2015

Purpose: Image registration is one prerequisite for the analysis of brain regions in magnetic-resonance-imaging (MRI) or positron-emission-tomography (PET) studies. Diffeomorphic anatomical registration through exponentiated Lie algebra (DARTEL) is a nonlinear, diffeomorphic algorithm for image registration and construction of image templates. The goal of this small animal study was (1) the evaluation of a MRI and calculation of several cannabinoid type 1 (CB1) receptor PET templates constructed using DARTEL and (2) the analysis of the image registration accuracy of MR and PET images to their DARTEL templates with reference to analytical and iterative PET reconstruction algorithms. Methods:…

medicine.diagnostic_testComputer sciencebusiness.industryImage registrationMagnetic resonance imagingPattern recognitionImage processingGeneral MedicineIterative reconstructionScintigraphyRegularization (mathematics)White mattermedicine.anatomical_structurePositron emission tomographyOrdered subset expectation maximizationSpatial normalizationmedicineMaximum a posteriori estimationTomographyArtificial intelligencebusinessNuclear medicineMedical Physics
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Increasing Stability of EEG Components Extraction Using Sparsity Regularized Tensor Decomposition

2018

Tensor decomposition has been widely employed for EEG signal processing in recent years. Constrained and regularized tensor decomposition often attains more meaningful and interpretable results. In this study, we applied sparse nonnegative CANDECOMP/PARAFAC tensor decomposition to ongoing EEG data under naturalistic music stimulus. Interesting temporal, spectral and spatial components highly related with music features were extracted. We explored the ongoing EEG decomposition results and properties in a wide range of sparsity levels, and proposed a paradigm to select reasonable sparsity regularization parameters. The stability of interesting components extraction from fourteen subjects’ dat…

medicine.diagnostic_testbusiness.industryComputer sciencePattern recognition02 engineering and technologyElectroencephalographystability analysisRegularization (mathematics)ongoing EEG03 medical and health sciences0302 clinical medicinetensor decomposition0202 electrical engineering electronic engineering information engineeringmedicineTensor decompositionsparse regularization020201 artificial intelligence & image processingArtificial intelligencebusiness030217 neurology & neurosurgerynonnegative constraints
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Prevalence of Catatonia and Its Moderators in Clinical Samples: Results from a Meta-analysis and Meta-regression Analysis

2017

Catatonia is an independent syndrome that co-occurs with several mental and medical conditions. We performed a systematic literature review in PubMed/Scopus until February 2017 and meta-analyzed studies reporting catatonia prevalence. Across 74 studies (cross-sectional = 32, longitudinal = 26, retrospective = 16) providing data collected from 1935 to 2017 across all continents, mean catatonia prevalence was 9.0% (k = 80, n = 110 764; 95% CI = 6.9-11.7, I2 = 98%, publication bias P < .01), decreasing to 7.8% (k = 19, n = 7612, 95% CI = 7-8.7, I2 = 38.9%) in a subgroup with low heterogeneity. Catatonia prevalence was 23.9% (k = 8, n = 1168, 95% CI = 10-46.9, I2 = 96%) in patients undergoin…

medicine.medical_specialtyCatatoniaTranstornos Mentaisprevalencemeta-analysiDSM-503 medical and health sciencesDSM5; catatonia; meta-analysis; prevalence; severe mental illness0302 clinical medicineDSM5catatonia meta-analysis DSM5 severe mental illness prevalenceRating scaleInternal medicinesevere mental illnessmedicineHumansMeta-regressionPsychiatryMental DisordersCatatoniaPublication biasmedicine.disease030227 psychiatrymeta-analysisPsychiatry and Mental healthSample size determinationMeta-analysisMajor depressive disordercatatoniaPsychology030217 neurology & neurosurgeryRegular Articles
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Associations between parenting and substance use, meal pattern and food choices: A cross-sectional survey of 13,269 Norwegian adolescents

2019

Identifying factors that affect adolescent lifestyle behaviors is essential in order to develop effective generic prevention approaches. This study aimed to investigate the association between parental monitoring, parental emotional support, parental-adolescent conflict and adolescent substance use, meal pattern and food choices. The study included data from 13,269 Norwegian adolescents aged 13–16 years collected in 2016. Multivariable logistic regression models adjusted for gender, age and parental education were applied. Results show that low parental monitoring was associated with increased substance use (Odds ratios (OR) ranging from 2.8; 95% Confidence intervals (CI) 2.1–3.6 to OR 3.8;…

medicine.medical_specialtyCross-sectional studyPsychological interventionlcsh:Medicine030209 endocrinology & metabolismHealth InformaticsNorwegianDiet food and nutritionLogistic regression03 medical and health sciences0302 clinical medicineEnvironmental healthFood choiceMedicine030212 general & internal medicineMealsCannabisParentingbiologybusiness.industryPublic healthlcsh:RSmokingPublic Health Environmental and Occupational HealthRegular ArticleOdds ratioAdolescent alcohol useVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850biology.organism_classificationlanguage.human_languagelanguageCannabisbusinessPreventive Medicine Reports
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Role of exercise-induced hepatokines in metabolic disorders.

2019

International audience; The health-promoting effects of physical activity to prevent and treat metabolic disorders are numerous. However, the underlying molecular mechanisms are not yet completely deciphered. In recent years, studies have referred to the liver as an endocrine organ, since it releases specific proteins called hepatokines. Some of these hepatokines are involved in whole body metabolic homeostasis and are theorized to participate in the development of metabolic disease. In this regard, the present review describes the role of Fibroblast Growth Factor 21, Fetuin-A, Angiopoietin-like protein 4, and Follistatin in metabolic disease and their production in response to acute exerci…

medicine.medical_specialtyFGF21PhysiologyEndocrinology Diabetes and MetabolismPhysical activity030209 endocrinology & metabolism03 medical and health sciences0302 clinical medicineMetabolic DiseasesRegular exerciseNon-alcoholic Fatty Liver DiseasePhysiology (medical)Internal medicineEndocrine systemMedicineAnimalsHumansObesityMetabolic diseaseBeneficial effectsExercise030304 developmental biology0303 health sciencesbiologybusiness.industry[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism3. Good healthEndocrinologyDiabetes Mellitus Type 2Liverbiology.proteinCytokinesInsulin ResistanceWhole bodybusinessFollistatinAmerican journal of physiology. Endocrinology and metabolism
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Progressive Endoplasmic Reticulum Stress Contributes to Hepatocarcinogenesis in Fatty Acyl-CoA Oxidase 1–Deficient Mice

2011

Fatty acyl-coenzyme A oxidase 1 (ACOX1) knockout (ACOX1(-/-)) mice manifest hepatic metabolic derangements that lead to the development of steatohepatitis, hepatocellular regeneration, spontaneous peroxisome proliferation, and hepatocellular carcinomas. Deficiency of ACOX1 results in unmetabolized substrates of this enzyme that function as biological ligands for peroxisome proliferator-activated receptor-α (PPARα) in liver. Here we demonstrate that sustained activation of PPARα in ACOX1(-/-) mouse liver by these ACOX1 substrates results in endoplasmic reticulum (ER) stress. Overexpression of transcriptional regulator p8 and its ER stress-related effectors such as the pseudokinase tribbles h…

medicine.medical_specialtyGenotypePeroxisome proliferator-activated receptorPeroxisome ProliferationMice TransgenicBiologyEndoplasmic ReticulumModels BiologicalPathology and Forensic MedicineMiceInternal medicinemedicineAnimalsHumansAcyl-CoA oxidasePPAR alphaTransgenesDNA Primerschemistry.chemical_classificationLiver cellEndoplasmic reticulumLiver NeoplasmsRegular ArticlePeroxisomemedicine.diseaseNeoplasm ProteinsCell biologyDNA-Binding ProteinsMice Inbred C57BLEndocrinologyGene Expression RegulationLiverchemistryHepatocytesUnfolded protein responseAcyl-CoA OxidaseSteatohepatitisThe American Journal of Pathology
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2021

The purpose of this study was to investigate the prevalence of self-reported restrictive eating, current or past eating disorder, and menstrual dysfunction and their relationships with injuries. Furthermore, we aimed to compare these prevalences and associations between younger (aged 15–24) and older (aged 25–45) athletes, between elite and non-elite athletes, and between athletes competing in lean and non-lean sports. Data were collected using a web-based questionnaire. Participants were 846 female athletes representing 67 different sports. Results showed that 25%, 18%, and 32% of the athletes reported restrictive eating, eating disorders, and menstrual dysfunction, respectively. Higher ra…

medicine.medical_specialtyNutrition and DieteticsSports injurybiologyAthletesbusiness.industrymedia_common.quotation_subjectLifetime prevalenceMenstrual irregularitybiology.organism_classificationmedicine.diseaseRestrictive eatingEating disordersPhysical therapyMedicineDisordered eatingbusinessMenstrual cycleFood Sciencemedia_commonNutrients
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Outcome of pregnancy in type 1 diabetic patients treated with insulin lispro or regular insulin: an Italian experience.

2008

Some studies have shown that fetal outcome observed in patients using insulin lispro is much the same as in pregnant women using regular insulin. This study aims to analyze the Italian data emerging from a multinational, multicenter, retrospective study on mothers with type 1 diabetes mellitus before pregnancy, comparing those treated with insulin lispro for at least 3 months before and 3 months after conception with those treated with regular insulin. The data collected on pregnant women with diabetes attending 15 Italian centers from 1998 to 2001 included: HbA1c at conception and during the first and third trimesters, frequency of severe hypoglycemic episodes, spontaneous abortions, mode …

medicine.medical_specialtyPediatricsneonatal mortalityendocrine system diseasesEndocrinology Diabetes and MetabolismBirth weightEndocrinologyPregnancyInternal medicineDiabetes mellitusInternal MedicineBirth WeightHumansHypoglycemic AgentsInsulinMedicineInsulin lisproChromatography High Pressure LiquidRetrospective StudiesGlycated HemoglobinType 1 diabetesPregnancyInsulin Lisprodiabetesbusiness.industryInfant Newbornnutritional and metabolic diseasesRetrospective cohort studyGeneral Medicinemedicine.diseasediabetes; malformations; neonatal mortality; pregnancyPregnancy ComplicationsDiabetes Mellitus Type 1EndocrinologyItalyInfant Small for Gestational AgeRegular insulinmalformationsSmall for gestational ageFemalebusinessmedicine.drug
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Enhanced inhibitory control during re-engagement processing in badminton athletes : An event-related potential study

2019

Highlights • Reaction time and event-related potentials of inhibitory control were compared in badminton experts and nonathletes. • Badminton experts showed enhanced inhibitory control and more efficient neural mechanisms. • Badminton experts performed better inhibitory control processing in re-engagement. • The re-engagement processing better demonstrated altered brain activity in badminton experts.

medicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationStimulus (physiology)behavioral disciplines and activitiesChange-signal task03 medical and health scienceslcsh:GV557-1198.9950302 clinical medicinePhysical medicine and rehabilitationsulkapalloilijatEvent-related potentialInhibitory controlmedicineRegular PaperOrthopedics and Sports Medicine030212 general & internal medicinelcsh:Sports medicineInhibitory controlskin and connective tissue diseasesstop-signal taskResponse inhibitionmotoriikkalcsh:Sportsbadminton athletes030229 sport scienceschange-signal taskERPsreaktiotStop-signal taskinhibitory controlBadminton athletesreaktionopeussense organskognitiivinen neurotiedePsychologylcsh:RC1200-1245psychological phenomena and processesEvent-related potentialsurheilijat
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An irregular atrial tachycardia : What is the underlying mechanism?

2017

medicine.medical_specialtySettore MED/09 - Medicina InternaMechanism (biology)business.industryECGP waveMEDLINE030204 cardiovascular system & hematology03 medical and health sciencesText mining0302 clinical medicineInternal medicineCardiologyMedicineIrregular tachycardia030212 general & internal medicinemedicine.symptomCardiology and Cardiovascular MedicinebusinessAtrial tachycardia
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