Search results for "Repair"

showing 10 items of 747 documents

Endovascular treatment options for complex abdominal aortic aneurysms

2015

Abstract Purpose To report short-term and midterm outcomes of endovascular aneurysm repair (EVAR) of complex aneurysms requiring revascularization of visceral arteries. Materials and Methods Prospective data were collected from patients deemed unsuitable for conventional EVAR and conventional surgery who were treated with different endovascular approaches according to the clinical presentation of the aneurysm. Custom-made fenestrated endovascular aneurysm repair (CM f-EVAR) was used in the elective setting, homemade fenestrated endovascular aneurysm repair (HM f-EVAR) or HM f-EVAR combined with chimney endovascular aneurysm repair (ch-EVAR) was used in the emergent setting in patients with …

Malemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingTime Factorsmedicine.medical_treatmentCustom-made fenestrated endovascular aneurysm repairProsthesis DesignRevascularizationAortographyEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareBlood Vessel Prosthesis ImplantationAortic aneurysmAneurysmBlood vessel prosthesismedicine.arterymedicineHumansRenal arterychimney endovascular aneurysm repairVascular PatencyAgedRetrospective StudiesAged 80 and overbusiness.industryhomemade fenestrated endovascular aneurysm repairEndovascular Procedureshomemade fenestrated endovascular aneurysm repair; Custom-made fenestrated endovascular aneurysm repair; chimney endovascular aneurysm repairPerioperativeMiddle Agedmedicine.diseaseBlood Vessel ProsthesisSurgeryVisceraTreatment OutcomeRegional Blood FlowFemaleStentsRadiologyTomography X-Ray ComputedbusinessCardiology and Cardiovascular MedicineBlood Flow VelocityAortic Aneurysm AbdominalAbdominal surgery
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Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain

2009

Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…

Malemedicine.medical_specialtyTime FactorsCentral nervous systemHippocampusCell CountSettore BIO/11 - Biologia MolecolareBiologySettore BIO/09 - Fisiologiachemistry.chemical_compoundSeizuresInternal medicineSettore BIO/10 - BiochimicaCaSRmedicineAnimalsRNA MessengerRats WistarIbotenic AcidMolecular BiologyIn Situ HybridizationNeuronsKainic AcidGeneral NeuroscienceDentate gyrusBrainColocalizationImmunohistochemistryRatsOligodendrogliamedicine.anatomical_structureEndocrinologynervous systemchemistryBrain InjuriesNeurogliaNeurology (clinical)Pyramidal cellCaSR; BrainCalcium sensing receptor (CaSR) isolated for the first time from bovine and human parathyroid is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expression in neurons and oligodendrocytes whereas it was not found expressed both in the microglia and in astrocytes. One week after kainate-induced seizure CaSR was found in the injured CA3 region of the hippocampus and very interestingly it was found up-regulated in the neurons of CA1-CA2 and dentate gyrus. Similarly 1 week following ibotenic acid injection in the hippocampus CaSR mRNA expression was increased in oligodendrocytes both in the lesioned area and in the contralateral CA1-CA3 pyramidal cell layers and dentate gyrus. One week after needle-induced mechanical lesion an increase of labeled cells expressing CaSR mRNA was observed along the needle track. In conclusion the present results contribute to extend available data on cell type-expressing CaSR in normal and injured brain and could spur to understand the role of CaSR in repairing processes of brain injury.Receptors Calcium-SensingIbotenic acidDevelopmental BiologyAstrocyte
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Mid-Term Results of Endovascular Aneurysm Sealing in the Treatment of Abdominal Aortic Aneurysm With Unfavorable Morphology.

2020

Purpose: To report mid-term results of endovascular aneurysm sealing (EVAS) of abdominal aortic aneurysms (AAA) deemed unsuitable for a standard endovascular aneurysm repair (EVAR). Methods: A prospectively maintained database of 42 patients with EVAR-unfavorable anatomy treated by EVAS combined with chimney grafts in case of the proximal AAA neck shorter than 5 mm was analyzed. Early outcomes included final angiographic result, intra- and early post-operative deaths, and complications. Mid-term outcomes included all-cause mortality (ACM), aneurysm-related mortality (ARM), patency of the stents, occurrence of endoleaks, serious complications and graft failures defined as the AAA growth of m…

Malemedicine.medical_specialtyTime FactorsDatabases Factualmedicine.medical_treatmentMid term results030204 cardiovascular system & hematologyEndovascular aneurysm repairRisk AssessmentNellix device03 medical and health sciencesBlood Vessel Prosthesis Implantationabdominal aortic aneurysm0302 clinical medicineAneurysmPostoperative ComplicationsRisk Factorschimney graftsmedicineHumans030212 general & internal medicineVascular PatencyAgedendovascular aneurysm sealingbusiness.industryEndovascular ProceduresGeneral MedicineMiddle Agedmedicine.diseaseAbdominal aortic aneurysmSurgeryBlood Vessel ProsthesisProsthesis FailureTreatment OutcomeSurgeryFemaleStentsCardiology and Cardiovascular Medicinebusinessoutside IFUAortic Aneurysm AbdominalVascular and endovascular surgery
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Does adding a 12-month exercise programme to usual care after a rotator cuff repair effect disability and quality of life at 12 months? A randomized …

2013

Objective: To compare a 12-month home-based exercise programme with usual care for disability and health-related quality of life after rotator cuff repair. Design: Randomized controlled trial. Setting: Outpatient physical and rehabilitation medicine clinic. Subjects: Consecutive patients ( n = 67, mean age 54 years) who underwent rotator cuff repairs were randomized into an experimental group (EG) or a usual care group (UCG). Interventions: The UCG received ordinary postoperative instructions, while the EG were given advice and instructions on a shoulder muscle strengthening programme to be undertaken at home. Main measures: Disability was assessed with the American Shoulder and Elbow Surge…

Malemedicine.medical_specialtyTime FactorsElbowPhysical Therapy Sports Therapy and RehabilitationRotator Cuff Injurieslaw.inventionPhysical medicine and rehabilitationRandomized controlled trialQuality of lifeShoulder PainTendon InjurieslawmedicineHumansRotator cuffRange of Motion Articularexercisebusiness.industryRehabilitationta3141Mean ageMiddle Agedrotator cuff repairHome Care ServicesExercise TherapyExercise programmeTreatment Outcomemedicine.anatomical_structuredisabilityrandomized controlled trialUsual careQuality of LifePhysical therapyFemalebusinessUsual care groupClinical Rehabilitation
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Impact of Accessory Renal Artery Coverage on Renal Function during Endovascular Aortic Aneurysm Repair.

2021

Background Long-term outcomes of accessory renal artery (ARA) coverage after endovascular aneurysm repair (EVAR) are unknown. We analyzed the impact of ARA coverage on renal function long-term. Methods This retrospective, monocentric study included patients treated by EVAR between 2008 and 2016. Patients with at least one ARA covered with EVAR (ARA group) were compared with patients with no covered ARA (control group). Renal function was determined by estimating the glomerular filtration rate (eGFR) and graded according to chronic kidney disease (CKD) classification stages. Results A total of 184 patients were included (ARA group, n = 25; control group, n = 159). Renal risk factors were sim…

Malemedicine.medical_specialtyTime FactorsRenal infarctionmedicine.medical_treatmentUrologyRenal function030204 cardiovascular system & hematologyKidneyEndovascular aneurysm repair030218 nuclear medicine & medical imagingAccessory renal artery03 medical and health sciencesBlood Vessel Prosthesis Implantation0302 clinical medicineRenal ArterymedicineHumansStage (cooking)Renal Insufficiency ChronicSuprarenal fixationAgedRetrospective StudiesAged 80 and overAortic aneurysm repairbusiness.industryEndovascular Proceduresfood and beveragesGeneral Medicinebiochemical phenomena metabolism and nutritionmedicine.diseaseAortic AneurysmBlood Vessel Prosthesiscarbohydrates (lipids)Treatment OutcomeDisease ProgressionSurgeryFemaleCardiology and Cardiovascular MedicinebusinessKidney diseaseGlomerular Filtration RateAnnals of vascular surgery
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Endovascular versus open surgical repair of abdominal aortic aneurysm with concomitant malignancy

2007

Background The management of patients with abdominal aortic aneurysm (AAA) and concurrent malignancy is controversial. This study retrospectively assessed the outcome of endovascular repair (EVAR) and open repair (OR) for the treatment of AAA in patients undergoing curative treatment for concomitant malignancies. Methods All patients who underwent surgery for a nonruptured infrarenal AAA of ≥5.5 cm and concomitant malignancy between 1997 and 2005 were retrospectively reviewed. Results Identified were 25 patients (22 men; mean age, 70.3 years) with nonruptured infrarenal AAA of ≥5.5 cm (mean size, 6.4 cm) and concomitant malignancy amenable for curative treatment. EVAR was used to treat 11 p…

Malemedicine.medical_specialtyTime FactorsTime FactorKaplan-Meier EstimateMalignancySettore MED/22 - Chirurgia VascolareFollow-Up StudieAortic aneurysmAneurysmPostoperative Complicationsabdominal aortic aneurysmRetrospective StudieNeoplasmsmedicineHumansEVARAgedRetrospective StudiesAged 80 and overbusiness.industryMortality rateOpen repairGreat BritainRetrospective cohort studyLength of StayMiddle Agedmedicine.diseaseAbdominal aortic aneurysmUnited KingdomSurgeryTreatment OutcomeItalyConcomitantNeoplasmFemaleSurgeryRadiologyPostoperative ComplicationbusinessCardiology and Cardiovascular MedicineVascular Surgical ProceduresAbdominal surgeryHumanAortic Aneurysm AbdominalFollow-Up StudiesmalignancyJournal of Vascular Surgery
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Initial Clinical Experience Using the Low-Profile Altura Endograft System With Double D-Shaped Proximal Stents for Endovascular Aneurysm Repair.

2018

Purpose: To report the initial clinical results of endovascular aneurysm repair (EVAR) using the low-profile (14-F) Altura Endograft System, which features a double “D-shaped” stent design with suprarenal fixation and modular iliac components that are deployed from distal to proximal. Methods: From 2011 to 2015, 90 patients (mean age 72.8±8.3 years; 79 men) with abdominal aortic aneurysm (AAA; mean diameter 53.8±5.7 mm) were treated at 10 clinical sites in 2 prospective, controlled clinical studies using the Altura endograft. Outcomes evaluated included mortality, major adverse events (MAEs: all-cause death, stroke, paraplegia, myocardial infarction, respiratory failure, bowel ischemia, an…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatment030204 cardiovascular system & hematologyProsthesis DesignEndovascular aneurysm repairRisk Assessment03 medical and health sciencesBlood Vessel Prosthesis Implantation0302 clinical medicinePostoperative ComplicationsRisk FactorsmedicineHumansRadiology Nuclear Medicine and imaging030212 general & internal medicineMyocardial infarctionAdverse effectStrokeAgedAged 80 and overbusiness.industryPatient SelectionEndovascular ProceduresMiddle Agedmedicine.diseaseThrombosisAbdominal aortic aneurysmSurgeryBlood Vessel ProsthesisProsthesis FailureTreatment OutcomeRespiratory failureSurgeryFemaleStentsCardiology and Cardiovascular MedicineParaplegiabusinessAortic Aneurysm AbdominalJournal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
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CT Angiography at 24 Months Demonstrates Durability of EVAR With the Use of Chimney Grafts for Pararenal Aortic Pathologies

2013

PURPOSE: To present the 24-month radiological follow-up data for patients with pararenal aortic pathologies treated with chimney and periscope grafts during endovascular repair. METHODS: Between January 2008 and December 2011, 124 high-risk patients with complex pararenal aortic pathologies were treated using the chimney technique at 2 European vascular and cardiovascular centers with advanced experience of the described technique. In particular, 50 patients were treated at Site 1 and 74 at Site 2. Forty (32.2%) patients (32 men; mean age 79.2±4.9 years) completed computed tomographic angiography follow-up at 24 months postoperatively. RESULTS: The overall technical success was 100%, and th…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentAortic Diseases610 Medicine & healthEndovascular aneurysm repair2705 Cardiology and Cardiovascular MedicineAortic aneurysmAneurysmmedicine.arterymedicineHumans2741 Radiology Nuclear Medicine and ImagingRadiology Nuclear Medicine and imagingAorta AbdominalEmbolizationSuperior mesenteric arteryAgedendovascular aneurysm repair chimney graft periscope graft pararenal aortic pathologies aortic aneurysm para-anastomotic aneurysm ruptured aneurysm stent-graft balloon-expandable stent-graft computed tomographic angiography endoleak renal arteries superior mesenteric artery sac shrinkage sac expansionmedicine.diagnostic_test10042 Clinic for Diagnostic and Interventional Radiologybusiness.industryEndovascular ProceduresAngiographyPerioperativemedicine.diseaseBlood Vessel Prosthesis10020 Clinic for Cardiac Surgery2746 SurgerySurgeryCuffAngiographyFemaleStentsSurgeryRadiologyTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesJournal of Endovascular Therapy
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The Gore Hybrid Vascular Graft in renovisceral debranching for complex aortic aneurysm repair.

2016

Objective This study reports our initial experience with the Gore Hybrid Vascular Graft (GHVG; W. L. Gore & Associates, Flagstaff, Ariz) for staged hybrid open renovisceral debranching and endovascular aneurysm repair in patients affected by thoracoabdominal aortic aneurysms and pararenal abdominal aortic aneurysms (PAAAs). Methods Between December 2012 and December 2013, we analyzed outcomes of 13 patients who underwent open surgical debranching of renovisceral vessels for thoracoabdominal aortic aneurysm and PAAAs. All patients were considered at high risk for conventional surgery. Inclusion criterion was treatment by open surgical debranching of at least one visceral artery (renal artery…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentAortic RuptureKaplan-Meier Estimate030204 cardiovascular system & hematologyAnastomosisRevascularizationProsthesis DesignEndovascular aneurysm repairThoracic aortic aneurysmSettore MED/22 - Chirurgia VascolareDisease-Free Survival03 medical and health sciencesAortic aneurysmBlood Vessel Prosthesis Implantation0302 clinical medicineAneurysmPostoperative ComplicationsBlood vessel prosthesisRisk Factorsmedicine.arterymedicineHumans030212 general & internal medicineRenal arteryVascular PatencyAgedRetrospective StudiesAortic Aneurysm Thoracicbusiness.industryEndovascular ProceduresCardiology and Cardiovascular Medicine; SurgeryMiddle Agedmedicine.diseaseSurgeryBlood Vessel ProsthesisTreatment Outcomecardiovascular systemFeasibility StudiesSurgeryFemaleRadiologybusinessCardiology and Cardiovascular MedicineAortic Aneurysm AbdominalJournal of vascular surgery
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Preputial reconstruction in hypospadias repair

2017

Summary Objective In principle, the prepuce can be reconstructed during hypospadias repair, but the procedure has not gained wide acceptance and preputial reconstruction (PR) is surrounded by several controversies. Material and methods A review is provided of the technique for PR, how PR combines with the other steps of hypospadias repair, the risks of complications related to the urethroplasty and specific to PR, and the results of PR with particular regard to the relevance for the patient and his family. Results PR can be important for patients requiring hypospadias repair and their parents. It can be performed in almost all patients with distal hypospadias except perhaps those with the m…

Malemedicine.medical_specialtyUrologic Surgical Procedures MaleComplicationsUrologyUrethroplastymedicine.medical_treatmentForeskin030232 urology & nephrologyPreputial glandDehiscenceComplications; Hypospadias; Prepuce; Preputial reconstruction; PreputioplastyPrepucePreputioplasty03 medical and health sciencesPreputial reconstruction0302 clinical medicinemedicineHypospadias repairHumansIn patientReconstructive Surgical ProceduresHypospadiasUrethral platebusiness.industryPlastic Surgery Proceduresmedicine.diseaseComplications; Hypospadias; Prepuce; Preputial reconstruction; Preputioplasty; Foreskin; Humans; Hypospadias; Male; Reconstructive Surgical Procedures; Urologic Surgical Procedures MaleSurgeryPreputioplastyHypospadias030220 oncology & carcinogenesisPediatrics Perinatology and Child HealthUrologic Surgical ProceduresHypospadiabusinessComplication
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