Search results for "Repo"
showing 10 items of 2753 documents
Use of Tense-Aspect Forms in Cordis Project Reports
2019
For several recent decades the Council of Europe and various European authorities have been encouraging various European universities and other institutions to unite research activities resulting in the creation of partnerships with a conventialised genre network of calls for projects, guidelines for proposals and databases of project documentation. Along with Latvia acting in political, economic and social arenas of the European Union, it has also been actively involved in research consortia as coordinator and participant, therefore, setting new objectives for communicative competence development of scholars and project managers in order to reflect the discursive practices. In view of this…
Open educational resources repositories literature review – Towards a comprehensive quality approaches framework
2015
Display Omitted A comprehensive literature review on learning object repositories (LOR) quality approaches.Most cited quality approaches are "peer reviews" and "recommendation systems".User-generated, collaborative, quality instruments are favored for their sustainability.Main result is a Quality approach framework for LOR design. Today, Open Educational Resources (OER) are commonly stored, used, adapted, remixed and shared within Learning object repositories (LORs) which have recently started expanding their design to support collaborative teaching and learning. As numbers of OER available freely keep on growing, many LORs struggle to find sustainable business models and get the users' att…
Zobu sakņu rezorbcija: Literatūras un gadījuma apskats
2020
Biežāk netīša gadījuma atradne - saknes rezorbcija (iekšēja vai ārēja) - ir asociēta ar zobu audu, kā arī ar alveolārā kaula lokālu zudumu sakarā ar pastiprinātu osteoklastu funkciju darbību. Visbiežāk asimptomātisku procesu novēro kā patoloģisku procesu patstāvīgā zoba audos vai arī fizioloģisku procesu maiņas sakodienā. Šī gadījuma analīze ietver literatūras apskatu par saknes rezorbcijas etioloģiju, riska un predisponējošiem faktoriem, diagnozes uzstādīšanu un klasifikāciju, kā arī ārstēšanu. Gadījuma analīze: Perforējoša zoba saknes kakliņa daļas rezorbcija.
Contrast ultrasound LI-RADS LR-5 identifies hepatocellular carcinoma in cirrhosis in a multicenter restropective study of 1,006 nodules
2018
Background & Aims The use of contrast enhanced ultrasound (CEUS) for the diagnosis of hepatocellular carcinoma (HCC) in cirrhosis was questioned because of the risk of a false positive diagnosis in cases of cholangiocarcinoma. The American College of Radiology has recently released a scheme (CEUS Liver Imaging Reporting and Data System [LI-RADS®]) to classify lesions at risk of HCC investigated by CEUS. The aim of the present study was to validate this LI-RADS scheme for the diagnosis of HCC. Methods A total of 1,006 nodules from 848 patients with chronic liver disease at risk of HCC were collected in five Italian centers and retrospectively analyzed. Nodules were classified as LR-5, (HCC) …
Association Between Serum Levels of Neurofilament Light Chains and Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis.
2021
INTRODUCTION: Serum biomarkers for the diagnosis of minimal hepatic encephalopathy (MHE) in patients with liver cirrhosis would be desirable. In this proof-of-concept study, we investigated the association between MHE and serum levels of neurofilament light chains (sNfL) in patients with liver cirrhosis. METHODS: sNfL were studied in patients with liver cirrhosis (with or without MHE) and controls (patients with ischemic stroke, transitory ischemic attack, and healthy individuals). MHE was diagnosed using the Psychometric Hepatic Encephalopathy Score. RESULTS: Patients with MHE showed higher sNfL than patients without MHE and controls. In multivariable analyses, higher sNfL were independent…
Impact of antithrombin III on hepatic and intestinal microcirculation in experimental liver cirrhosis and bowel inflammation: An in vivo analysis
2005
AIM: To analyze the hepatic and intestinal microcirculation in an animal model of liver cirrhosis and inflammatory bowel disease (IBD) and to characterize the anti-inflammatory action of antithrombin III (ATIII) on leukocyte kinetics and liver damage. METHODS: Hepatic and intestinal microcirculation was investigated by intravital videomicroscopy. Standardized models of experimental chronic liver cirrhosis and bowel inflammation were employed. Animals were divided into four groups (n = 6/group): controls, animals with cirrhosis, animals with cirrhosis and IBD, animals with cirrhosis and IBD treated with ATIII. RESULTS: Cirrhosis facilitated leukocyte rolling and sticking in hepatic sinusoids…
Long-lasting tumor response on short-time administration of vemurafenib—A case report
2014
Vemurafenib has been approved since 2011 in the United States for the treatment of advanced BRAF V600–mutated melanoma as first-line therapy. Although it significantly prolongs overall and progression-free survival, most patients relapse within 6 to 8 months owing to acquisition of drug resistance. New findings suggest that discontinuous dose administration of vemurafenib might prolong response to vemurafenib, but it is unclear whether modified cell signalling or other mechanisms, such as immune-mediated effects, are responsible for this effect.
Physico-chemical evolution of low-pH cements : influence of the temperature and the retention mechanisme of alkalins
2010
Because of their high alkalinity, Portland cement (OPC)-based materials may have deleterious effects in an underground waste repository. A solution would be to use low-alkalinity cements (also referred as low-pH cements) generating interstitial solutions with a reduced pH (11 instead of 13.5 for OPC), and thus showing an improved chemical compatibility with the repository environment. In this work, the investigated formulations were based on binary (OPC / silica fume) or ternary (OPC / silica fume / slag or fly ash) blends, with high substitution levels of CEM I (from 30% to 80%). This research project met two main objectives: (i) study the chemical evolution of low-pH cements at 50°C or 80…
Severe tetracycline dental discoloration: Restoration with conventional feldspathic ceramic veneers. A clinical report
2017
The treatment of severe tetracycline discoloration is a challenge for the dentist. There are several treatment options and one of the most effective is the use of feldspathic veneers. The aim of this clinical case was to carry out the replacement with conventional feldspathic ceramic veneers on a patient with highly stained teeth (grade IV tetracycline) by a minimally invasive approach. Clinical examination revealed gingival retraction, color change of the veneers, ceramic cracked of 1.1 and 1.3 and incisal wear in lower anterior teeth. The decision was to retreat with feldspathic ceramic veneers from 1.6 to 2.6. Premolars and first molars were included because its dark color intensifies th…
Congenital emphysematous lung disease associated with a novel Filamin A mutation. Case report and literature review
2019
Abstract Background Progressive lung involvement in Filamin A (FLNA)-related cerebral periventricular nodular heterotopia (PVNH) has been reported in a limited number of cases. Case presentation We report a new pathogenic FLNA gene variant (c.7391_7403del; p.Val2464Alafs*5) in a male infant who developed progressive lung disease with emphysematous lesions and interstitial involvement. Following lobar resection, chronic respiratory failure ensued necessitating continuous mechanical ventilation and tracheostomy. Cerebral periventricular nodular heterotopia was also present. Conclusions We report a novel variant of the FLNA gene, associated with a severe lung disorder and PNVH. The lung disord…