Search results for "Repo"
showing 10 items of 2753 documents
Knowledge, opinions and attitudes of Italian mothers towards HPV vaccination and Pap test
2015
Aim This study evaluated the knowledge and attitudes of Italian mothers – whose daughters had been vaccinated in 2012 – towards primary (anti-HPV vaccination) and secondary (Pap test screening) cervical cancer prevention, as well as sources of information and mother-daughter communication on health issues. Methods The survey – part of a multicenter study carried out in 4 Italian cities (Ferrara, Rome, Cassino and Palermo) – was conducted through self-administered questionnaires. The first univariate analysis evaluated differences between mothers of under-18s and over-18s relative to knowledge and attitudes on HPV vaccination and Pap test. The second univariate analysis evaluated differences…
ACTION POTENTIAL, MEMBRANE CURRENTS AND FORCE OF CONTRACTION IN MAMMALIAN HEART MUSCLE FIBRES TREATED WITH QUINIDINE
1978
The effects of quinidine on electrical and mechanical activity were investigated in atrial and/or ventricular heart muscle preparations from guinea pigs and cats. Quinidine (1--100 micrometer) exerted negative inotropic effects in papillary muscles from guinea pigs and cats. In guinea-pig left atria, a positive inotropic effect was superimposed on the negative inotropic effect in response to quinidine. Quinidine (100 micrometer) prolonged the duration of the action potential in guinea-pig atria but shortened it in guinea-pig ventricular muscle. In cat papillary muscles, the late repolarization was markedly prolonged by quinidine, but virtually no change of the plateau phase was observed. Th…
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune r…
2010
Vaccination with in vitro transcribed RNA coding for tumor antigens is considered a promising approach for cancer immunotherapy and has already entered human clinical testing. One of the basic objectives for development of RNA as a drug is the optimization of immunobioavailability of the encoded antigen in vivo. By analyzing the effect of different synthetic 5' mRNA cap analogs on the kinetics of the encoded protein, we found that m(2)(7,2'-O)Gpp(S)pG (beta-S-ARCA) phosphorothioate caps, in particular the D1 diastereoisomer, profoundly enhance RNA stability and translational efficiency in immature but not mature dendritic cells. Moreover, in vivo delivery of the antigen as beta-S-ARCA(D1)-c…
Technical design report for the upgrade of the ALICE inner tracking system
2014
ALICE (A Large Ion Collider Experiment) is studying the physics of strongly interacting matter, and in particular the properties of the Quark–Gluon Plasma (QGP), using proton–proton, proton–nucleus and nucleus–nucleus collisions at the CERN LHC (Large Hadron Collider). The ALICE Collaboration is preparing a major upgrade of the experimental apparatus, planned for installation in the second long LHC shutdown in the years 2018–2019. A key element of the ALICE upgrade is the construction of a new, ultra-light, high- resolution Inner Tracking System (ITS) based on monolithic CMOS pixel detectors. The primary focus of the ITS upgrade is on improving the performance for detection of heavy-flavour…
The importance of bioceramics and computed tomography in the late clinical management of a horizontal root fracture : a case report
2020
Root fractures resulting from dental trauma involve dentin, cementum and pulp. The present study aimed to demonstrate the importance of cone-beam computed tomography (CBTC) and bioceramics in the correct planning and intervention of a horizontal root fracture case in tooth 11 with late treatment in an 18-year-old patient. Clinical and radiographic examinations revealed tooth displacement, pain on vertical percussion and images suggestive of a horizontal root fracture. Pulp necrosis was diagnosed and CBTC was requested for treatment planning. Subsequently, endodontic treatment was performed using a bioceramic apical plug. A 2-year follow-up indicated the absence of root resorption and normal…
"Osteolipoma of buccal mucosa: Case report and literature review"
2016
Osteolipoma affecting oral cavity is indeed rare. We hereby report a case of osteolipoma affecting buccal mucosa. A review of literature of osteolipoma of oral cavity, particularly on radiographic/imaging findings was done. Only 16 cases of Osteolipoma of oral cavity are reported in the literature. The radiographic findings of our case, i.e. multiple dense homogenous radio-opaque structures was reported earlier only in one case [out of 16] of osteolipoma of oral cavity. Key words:Lipoma, osteolipoma, panoramic radiography, radio-opaque, radiography.
Lowering of the mouth floor and vestibuloplasty to support a mandibular overdenture retained by two implants. A case report
2014
In Oral Implantology most of the procedures are predictable and have high success rates. The use of osseointegrated implants as a therapeutic option for the rehabilitation of patients with severe mandibular atrophy has decreased the need for pre-prosthetic surgery Nevertheless, complications may occur during implant surgery and also once the prosthesis has been placed. This paper describes the case of a totally edentulous patient with an upper complete removable denture and an implant-retained overdenture with two implants in the intermentonian region. During clinical examination, the implant abutments were totally covered by soft tissue since the floor of the mouth was elevated. The panora…
Ra223 in bone metastases with osteolytic activity
2018
Radium 223 dichloride (Ra223) is the only targeted alpha therapy able to extend survival in patients with bone metastases from prostate cancer. Mechanism of action and data currently available focused mainly on osteoblastic metastases from prostate cancer. In our institution, a patient with breast cancer affected by osteolytic metastases was treated with off-label use of Ra223. The evaluation of the deposit areas of Ra223 showed a perfect overlap with the regions of osteolysis previously detected by scintigraphy, indicating a possible therapeutic effect. This case report is the first document attesting Ra223 deposit in osteolytic metastases opening new opportunity of therapeutic development…
Chapter 7 HITRAP: A Facility at GSI for Highly Charged Ions
2008
Abstract An overview and status report of the new trapping facility for highly charged ions at the Gesellschaft fur Schwerionenforschung is presented. The construction of this facility started in 2005 and is expected to be completed in 2008. Once operational, highly charged ions will be loaded from the experimental storage ring ESR into the HITRAP facility, where they are decelerated and cooled. The kinetic energy of the initially fast ions is reduced by more than fourteen orders of magnitude and their thermal energy is cooled to cryogenic temperatures. The cold ions are then delivered to a broad range of atomic physics experiments.
La gestione dei conflitti: un’analisi descrittiva dai Rapporti di Autovalutazione delle scuole della Provincia di Palermo
2019
Il presente contributo intende promuovere una riflessione sul tema della gestione dei conflitti in ambito scolastico a partire da un’analisi descrittiva dei Rapporti di Autovalutazione delle scuole del I ciclo della Provincia di Palermo riguardanti l’anno scolastico 2017/18. La rilevazione dei dati è avvenuta attraverso il portale del MIUR “Scuola in Chiaro”. In particolare, sono stati presi in considerazione gli indicatori appartenenti alla dimensione relazionale (3.2.f ) dell’area “Ambiente di apprendimento” della sezione “Processi” del RAV oltre agli eventuali indicatori elaborati dalla scuola e ai punti di forza e di debolezza elaborati sulla base di alcune domande stimolo fornite. L’an…