Search results for "Repo"
showing 10 items of 2753 documents
Crystal structure of the borabenzene–2,6-lutidine adduct
2015
In the title compound, C12H14BN, the complete molecule is generated by a crystallographic twofold axis, with two C atoms, the B atom and the N atom lying on the rotation axis. The dihedral angle between the borabenzene and pyridine rings is 81.20 (6)°. As well as dative electron donation from the N atom to the B atom [B—N = 1.5659 (18) Å], the methyl substituents on the lutidine ring shield the B atom, which further stabilizes the molecule. In the crystal, weak aromatic π–π stacking between the pyridine rings [centroid–centroid separation = 3.6268 (9) Å] is observed, which generates [001] columns of molecules.
Extremely Low Frequency Magnetic Fields Do Not Affect LTP-Like Plasticity in Healthy Humans.
2020
Introduction: Several studies explored, in vitro, the biological effects of extremely low-frequency magnetic fields (ELF-MFs) and reported the induction of functional changes in neuronal activity. In particular, ELF-MFs can influence synaptic plasticity both in-vitro and in animal models. Indeed, some studies reported an increase in long-term potentiation (LTP) whereas others suggested its reduction. However, no specific study has investigated such effect in humans. Aims: To evaluate whether ELF-MFs affect the propensity of the human cortex to undergo LTP-like plasticity. Methods: We designed a randomized, single-blind, sham-controlled, cross-over study on 10 healthy subjects. Cortical plas…
The C-X-C Motif Chemokine Ligand 1 Sustains Breast Cancer Stem Cell Self-Renewal and Promotes Tumor Progression and Immune Escape Programs
2021
Breast cancer (BC) mortality is mainly due to metastatic disease, which is primarily driven by cancer stem cells (CSC). The chemokine C-X-C motif ligand-1 (CXCL1) is involved in BC metastasis, but the question of whether it regulates breast cancer stem cell (BCSC) behavior is yet to be explored. Here, we demonstrate that BCSCs express CXCR2 and produce CXCL1, which stimulates their proliferation and self-renewal, and that CXCL1 blockade inhibits both BCSC proliferation and mammosphere formation efficiency. CXCL1 amplifies its own production and remarkably induces both tumor-promoting and immunosuppressive factors, includingSPP1/OPN,ACKR3/CXCR7,TLR4,TNFSF10/TRAILandCCL18and, to a lesser exte…
Integrated Sustainability Reports
2017
Disclosure of corporate social and environmental sustainability, resumed in ‘sustainability reports', have occupied most of the attention of accounting thought and practice over the last few decades. Evaluation of ecological footprint and social sensitiveness is becoming relevant also for the investors. The chapter presents institutional disclosure concerning social, environmental, and integrated (financial, social and environmental) issues in a threefold perspective. The first is a historical one: after some definitions the birth and development of sustainability reports are presented to the reader. The second is a theoretical one: a paradigm or framework is developed for including what va…
Digital selection of composite resin shade using cross polarized photography and a standardized white balance gray reference card
2021
Purpose The aim of the present case report was to describe, through a clinical case, a step-by-step technique, for the digital selection of composite resin shades using cross polarization and white balance employing a standardized reference card. Case Description After intraoral impression, a digital diagnostic wax up was developed. A 3D printed cast was used to fabricate a lingual polyvinyl siloxane matrix. First a cross-polarized image of the contralateral central incisor was taken in RAW format, using a gray reference card. The digital image was manipulated using this card as a reference, to obtain reliable color values. The obtained color values, from the contralateral central incisor, …
Impact of Storage Acquisition Intervals on the Cost-Efficiency of the Private vs. Public Storage
2012
The volume of worldwide digital content has increased nine-fold within the last five years, and this immense growth is predicted to continue in foreseeable future reaching 8ZB already by 2015. Traditionally, in order to cope with the growing demand for storage capacity, organizations proactively built and managed their private storage facilities. Recently, with the proliferation of public cloud infrastructure offerings, many organizations, instead, welcomed the alternative of outsourcing their storage needs to the providers of public cloud storage services. The comparative cost-efficiency of these two alternatives depends on a number of factors, among which are e.g. the prices of the public…
Approaching risk management from a new integrated perspective
2013
In recent years, risk management has acquired increasing relevance within the organizational realm. Although the Integrated Reporting Framework includes ‘risk’ as one of the content elements of the Integrated Report, its main purpose does not specifically relate to risk management. Drawing on the evolving academic debate, this chapter aims to provide an overview of the different approaches to risk management and to highlight the need for a broader and integrated perspective. The chapter ends by highlighting the potential contribution of this perspective to the Integrated Reporting Framework.
Financial crisis impact on sustainability reporting
2013
Purpose – The purpose of this paper is to shed some light on the effect of the current financial crisis on corporate social responsibility (CSR) reporting and CSR assurance strategies that companies disclose online to stakeholders, by dividing the time horizon into two periods, before 2008 and from 2008. Design/methodology/approach – The sample includes Spanish listed companies, differentiating CSR reporters from non CSR-reporters. Also distinguished in the CSR-reporters sample, are those companies that assure the CSR report from those that do not. The authors contrast whether there is a trend as regards CSR reporting and CSR assurance, depending on whether the crisis has already begun or …
Peripheral ameloblastoma: A case report
2020
Background Ameloblastoma is a rare tumor which develops from odontogenic epithelium and its remnants and it occurs in the jaws. Peripheral ameloblastomas are rare and benign extraooseous ameloblastomas which effects soft tissues. This case report declares a peripheral ameloblastoma which is a rare type of ameloblastoma. Material and methods 34 year old female patient referred with a complaint of a gingival growth at right lower premolar area. A firm and granular surfaced gingival growth with the color of pink and red and having 1.5x1 cm sizes was observed at the mentioned area. With an incision from lower right second incisor tooth to lower right second molar tooth a flap from bone was made…
Case Report: Insulinoma Presenting as Excessive Daytime Somnolence
2021
Currently, undiagnosed insulinomas remain a difficult clinical dilemma because its symptoms in most cases can easily be misdiagnosed as other diseases. In this article, we present the case of a 14-year-old girl who presented to our hospital with recurrent episodes of excessive daytime sleepiness and abnormal behavior during sleep that had been going on for 3 months. Insulinoma is a rare neuroendocrine tumor that causes excessive release of insulin, resulting in episodes of hypoglycemia. It usually manifests as autonomic sympathetic symptoms. These symptoms resolved rapidly with the administration of glucose. After successful removal of the tumor, daytime sleepiness and abnormal nighttime be…