Search results for "Report"

showing 10 items of 2364 documents

A Bimolecular Multicellular Complementation System for the Detection of Syncytium Formation: A New Methodology for the Identification of Nipah Virus …

2019

Fusion of viral and cellular membranes is a key step during the viral life cycle. Enveloped viruses trigger this process by means of specialized viral proteins expressed on their surface, the so-called viral fusion proteins. There are multiple assays to analyze the viral entry including those that focus on the cell-cell fusion induced by some viral proteins. These methods often rely on the identification of multinucleated cells (syncytium) as a result of cell membrane fusions. In this manuscript, we describe a novel methodology for the study of cell-cell fusion. Our approach, named Bimolecular Multicellular Complementation (BiMuC), provides an adjustable platform to qualitatively and quanti…

0301 basic medicinevirusesmembrane fusionlcsh:QR1-502virusNipah virusBiologyGiant Cells01 natural scienceslcsh:MicrobiologySmall Molecule Libraries03 medical and health sciencesVirus entryViral envelopeViral life cycleViral entryVirologyDrug DiscoveryHumansSyncytiumDrug discoveryBrief ReportbiomolèculesHigh-throughput screeningLipid bilayer fusionVirus InternalizationFusion proteinHigh-Throughput Screening Assays0104 chemical sciencesCell biologyBimolecular complementation010404 medicinal & biomolecular chemistryMulticellular organismHEK293 Cells030104 developmental biologyInfectious DiseasesViruses
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Can hip resurfacing be safely revised with short-stem total hip arthroplasty? A case series of six patients.

2021

Abstract Background The usage of short stems in primary total hip arthroplasty (THA) has constantly gained popularity over the last decade, however, to date, short stems are not eligible to be used as revision implants. The aim of this study was to retrospectively evaluate the outcome of revision surgery of failed hip resurfacing arthroplasty (HRA) using short-stem THA. Methods In a single center, retrospective analysis, 6 consecutive patients who were treated with a calcar-guided short stem after failure of HRA were evaluated. The mean follow-up was 3.25 years (SD 0.45). Patient reported outcome measurements (PROMs) were recorded using the Harris hip score (HHS) and The Western Ontario and…

030222 orthopedicsmedicine.medical_specialtyWOMACbusiness.industryVisual analogue scalemedicine.medical_treatment030229 sport sciencesOsteoarthritisStress shieldingmedicine.diseaseArthroplastyHip resurfacingSurgery03 medical and health sciences0302 clinical medicineHarris Hip ScoreMedicineOrthopedics and Sports MedicinePatient-reported outcomebusinessJournal of orthopaedics
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HIV infection with viro-immunological dissociation in a patient with polycystic kidney disease: Candidate for transplantation?

2016

Highlights • Autosomal dominant polycystic kidney disease is the most common among inherited cystic kidney diseases. • Patients with HIV infection are at risk of developing acute kidney injury and chronic kidney disease. • We provide the first report of HIV infection in a patient with polycystic kidney disease. • Lymphopenia should not contraindicate kidney transplantation in patients with HIV infection.

030232 urology & nephrologyHuman immunodeficiency virus (HIV)Case ReportViro-immunological dissociationmedicine.disease_causeVirological response03 medical and health sciences0302 clinical medicinePolycystic kidney diseaseLymphopeniaPolycystic kidney diseaseMedicine030212 general & internal medicineStage (cooking)Kidney transplantationTransplantationurogenital systembusiness.industryHIV; Lymphopenia; Polycystic kidney disease; Transplantation; Viro-immunological dissociation; Infectious Diseasesvirus diseasesHIVmedicine.diseaseAntiretroviral therapyTransplantationInfectious DiseasesImmunologybusinessIDCases
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C4 ‐dicarboxylates and l ‐aspartate utilization by Escherichia coli K‐12 in the mouse intestine: l ‐aspartate as a major substrate for fumarate respi…

2021

C4-dicarboxylates, such as fumarate, L-malate and L-aspartate represent substrates for anaerobic growth of Escherichia coli by fumarate respiration. Here, we determined whether C4-dicarboxylate metabolism as well as fumarate respiration contribute to colonization of the mammalian intestinal tract. Metabolite profiling revealed that the murine small intestine contained high and low levels of L-aspartate and L-malate, respectively, whereas fumarate was nearly absent. Under laboratory conditions, addition of C4-dicarboxylate at concentrations corresponding to the levels of the C4-dicarboxylates in the small intestine (2.6 mMol/kg dry weight) induced the dcuBp-lacZ reporter gene (67% of maximal…

0303 health sciencesReporter gene030306 microbiologyMutantMetabolismBiologymedicine.disease_causeMicrobiologySmall intestine03 medical and health sciencesmedicine.anatomical_structureBiochemistryRespirationmedicineAnaerobic exerciseEscherichia coliGeneEcology Evolution Behavior and Systematics030304 developmental biologyEnvironmental Microbiology
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Regenerative endodontic procedure combined with apical surgery of a necrotic permanent incisor with extensive periapical lesion using plasma rich in …

2021

Background The aim of this case report is to describe the step-by step and outcomes of a treatment approach which simultaneously combines a Regenerative Endodontic Procedure (REP) and apical surgery using PRGF as treatment of a post-traumatic necrotic permanent central incisor with extensive periapical lesion and undeveloped apex in a 16 years-old patient. Case description A 16 years-old patient with an extensive periapical lesion in the maxillary central incisor was treated with a combination of REP and periapical surgery in the same visit. A Bi- antibiotic paste (BAP) was used to priorly disinfect the canal, which was posteriorly sealed with MTA placed over a PRGF clot at the same time th…

0303 health sciencesbusiness.industryRadiographyRadiodensityDentistryCase Report030206 dentistryApex (geometry)Operative Dentistry and EndodonticsLesionPeriapical lesion03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureApical surgeryIncisorMedicineMaxillary central incisormedicine.symptombusinessGeneral DentistryUNESCO:CIENCIAS MÉDICAS030304 developmental biologyJournal of Clinical and Experimental Dentistry
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The Development and Initial Validation of a Short, Self-Report Measure on Social Inclusion for People with Intellectual Disabilities-A Transnational …

2021

Sport has been promoted as a means of increasing the social inclusion of persons with intellectual disabilities. Suitable tools for evaluating this claim are not readily available. The aim of this study was to develop a self-report tool for use by people with intellectual disabilities regarding the social inclusion they experience in sport and in the community. A three-phase process was used. In the first phase an item bank of questionnaire items was created and field-tested with 111 participants. Initial factor analysis identified 42 items which were further evaluated in Phase 2 with 941 participants from six European countries. Construct validity was established first through Exploratory …

030506 rehabilitationHealth Toxicology and MutagenesisApplied psychologyvammaisetPsychological interventionItem banklcsh:MedicineliikuntaurheiluSelf-report studySurveys and QuestionnairesIntellectual disabilityosallisuuskehitysvammaisetosallistuminenitsearviointibiology05 social sciencestransnationalConfirmatory factor analysissosiaaliset suhteetEuropeintellectual disabilitycommunitysocial inclusionsports0305 other medical sciencePsychologyInclusion (education)inkluusioPsychometricsSocial InclusionArticle03 medical and health sciencesyhteenkuuluvuusIntellectual Disability0502 economics and businessmedicineHumansself-report measuresAthleteslcsh:RPublic Health Environmental and Occupational HealthConstruct validityReproducibility of Resultsyhteisötmedicine.diseasebiology.organism_classificationSelf Report050212 sport leisure & tourismInternational journal of environmental research and public health
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Validity and reliability of the motivation for physical activity (RM4-FM) questionnaire

2021

There is a lack of validated instruments measuring motivation for physical activity (RM4-FM) in the Finnish language. The study examined the translated RM4-FM instrument’s psychometric properties in a sample of healthy, older Finnish adults. RM4-FM was translated and linguistically validated adhering to published guidelines. 65–75-year olds (n=102), completed the RM4-FM, the physical activity acceptance questionnaire (PAAQ) and sociodemographic characteristics questionnaires electronically. The RM4-FM was readministered one month after the initial assessment. RM4-FM translated well into Finnish. Motivation dimension scores were skewed towards high internal and low external motivation. A flo…

030506 rehabilitationValidityPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciences0302 clinical medicineFloor effectOrthopedics and Sports MedicineReliability (statistics)Self-determination theoryreliabiliteettimotivaatio030229 sport sciencesPatient-reported outcome measureExploratory factor analysisConfirmatory factor analysisSelf-determination theorypsykometriikkaPsychometric propertiesvaliditeettiScale (social sciences)mittarit (mittaus)Ceiling effectOriginal Article0305 other medical sciencePsychologyInactivityfyysinen aktiivisuusikääntyneetClinical psychologyJournal of Exercise Rehabilitation
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Impact of COVID-19 on the self-reported physical activity of people with complete thoracic spinal cord injury full-time manual wheelchair users

2021

Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Activitat física; Lesió medul·lar Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Actividad física; Lesión de la médula espinal Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Physical activity; Spinal cord injury Context The emergence of COVID-19 caused a new public health crisis, leading to major changes in daily life routines, often including physical activity (PA) levels. The main goal of this study was to analyze the differences in self-reported physical activity of people with complete spinal cord injuries between the time prior to the COVID-19 lockdown and the lockdown period itself. Methods A sample of 20 participants with complete thoracic spi…

030506 rehabilitationmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Clinical NeurologyPhysical activityManual wheelchair:terapéutica::terapéutica::modalidades de fisioterapia::terapéutica::tratamiento por actividad física [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitation:Therapeutics::Therapeutics::Physical Therapy Modalities::Therapeutics::Exercise Therapy [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]:virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES]Pandèmia de COVID-19 2020-HumansMedicine:enfermedades del sistema nervioso::enfermedades del sistema nervioso central::enfermedades de la médula espinal::traumatismos de la médula espinal [ENFERMEDADES]ExercisePandemicsSpinal cord injurySpinal Cord Injuriesbusiness.industryPublic healthCOVID-19:Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES]medicine.disease:Nervous System Diseases::Central Nervous System Diseases::Spinal Cord Diseases::Spinal Cord Injuries [DISEASES]WheelchairsCommunicable Disease ControlSelf ReportNeurology (clinical)0305 other medical sciencebusinessMedul·la espinal - Malalties - Exercici terapèutic030217 neurology & neurosurgeryThoracic spinal cord injuryThe Journal of Spinal Cord Medicine
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Evidential meanings of o eso dicen

2019

En este artículo se analizan los valores del significado evidencial transmitidos por la construcción o eso dicen. Se examinan los distintos patrones discursivos y sintácticos en los que dicha construcción aparece, así como su uso como marca de evidencialidad indirecta. El análisis se realiza a partir del Corpus de Español (sección Web/Dialects) y se centra en la variedad europea del español. Se concluye que o eso dicen transmite diferentes valores de evidencialidad, tales como significado reportativo, rumor y folclore que vienen determinados por factores relacionados con la fijación de la construcción, el tipo de la fuente de información a la que remite y el carácter del ámbito sobre el que…

050101 languages & linguisticsreportativesreportativitéreportative exceptionnalité05 social sciencesreportativosevidentialitySpanishévidentialité050105 experimental psychologyfolcloreexcepcionalidad reportativaespagnolespañol0501 psychology and cognitive sciencesfolkloreevidencialidadreportative exceptionality
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Development and Preliminary Validation of a Sport-Specific Self-Report Measure of Identity Foreclosure

2021

A sport-specific, self-report measure of identity foreclosure was developed through a systematic process that included item pool generation, expert review, administration of items to a development sample of intercollegiate student athletes (N = 326), item evaluation, and administration of scales to validation samples of intercollegiate student athletes (N = 322, N = 54, and N = 64, respectively). The process yielded two four-item scales reflecting commitment to the occupational identity of athlete and one 4-item scale reflecting active exploration of roles other than that of athlete that (a) are internally consistent and temporally stable, (b) demonstrate preliminary factorial and convergen…

050103 clinical psychology03 medical and health sciencesForeclosure (psychoanalysis)0302 clinical medicine05 social sciencesMeasure (physics)Identity (social science)0501 psychology and cognitive sciences030229 sport sciencesSelf reportPsychologySocial psychologyApplied PsychologyJournal of Clinical Sport Psychology
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