Search results for "Repository"
showing 10 items of 37 documents
Metadata to Support Data Warehouse Evolution
2009
The focus of this chapter is metadata necessary to support data warehouse evolution. We present the data warehouse framework that is able to track evolution process and adapt data warehouse schemata and data extraction, transformation, and loading (ETL) processes. We discuss the significant part of the framework, the metadata repository that stores information about the data warehouse, logical and physical schemata and their versions. We propose the physical implementation of multiversion data warehouse in a relational DBMS. For each modification of a data warehouse schema, we outline the changes that need to be made to the repository metadata and in the database.
How to Extract Fragments from Agent Oriented Design Processes
2013
Using Method Engineering for creating agent oriented design processes is a challenging task because of the lack of a fragment repository defined and filled starting from a shared and unique definition of fragment. The creation of a repository implies the fragmentation of existing agent design processes. In this paper we propose a set of guidelines for extracting fragments from agent design processes. The work is based on a precise definition of fragment and it aims to establish a method for fragmenting processes and obtaining homogeneous fragments regardless of how the starting design processes are defined and described. © 2013 Springer-Verlag.
The Software Crisis of Synthetic Biology
2016
In fifteen years, Synthetic Biology (SB) has moved from proof-of-concept designs to several flagship achievements. Standardisation efforts are still under way, basic engineering concepts such as modularity and orthogonality are still controversial in biology, and making predictions from computer models is still unreliable. A deep characterization in the pattern of re-use of biological blocks in SB has not been attempted to date. We have compared the topological organisation of two different technological networks, one associated to a standard, large-scale software repository and the second provided by the Registry of Standard Biological Parts (RSBP). Our results strongly suggest that softwa…
Drosophila Evolution over Space and Time (DEST) - A New Population Genomics Resource
2021
Abstract Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome datasets from natural populations of this species have been published over the last 20 years. A major challenge is the integration of these disparate datasets, often generated using different sequencing technologies and bioinformatic pipelines, which hampers our ability to address questions about the evolution and population structure of this species. Here we address these issues by developing a bioinformatics pipeline that maps pooled sequencing (Pool-Seq) reads from D. melanogaster to a hologenome consisting of fly and symbiont genomes and estimates allele frequenc…
La qualità inclusiva della scuola: dalle pratiche didattiche al profilo del docente inclusivo
2018
L’attenzione della ricerca pedagogica e didattica si rivolge con sempre maggiore consapevolezza ai fattori chiave dei processi di inclusione: la formazione degli insegnanti, lo sviluppo ed il monitoraggio dei contesti educativi nonché la produzione e l’incremento di pratiche didattiche inclusive. Attraverso la ricerca si sono voluti mettere a fuoco tali fattori chiave con la redazione di appositi strumenti che ne permettessero il controllo e la valutazione. Questo lavoro documenta una ricerca della durata di tre anni che ha visto coinvolti docenti in servizio, docenti in formazione frequentanti il terzo anno del corso di Laurea in Scienze della Formazione Primaria e alunni della scuola pri…
A discrete-choice experiment to assess patients’ preferences for osteoarthritis treatment: An ESCEO working group
2020
Objective: To evaluate the preferences of patients with osteoarthritis for treatment.Methods: A discrete-choice experiment was conducted among adult OA patients who were presented with 12 choice sets of two treatment options and asked in each to select the treatment they would prefer. Based on literature reviews, expert consultation, patient survey and expert meeting, treatment options were characterized by seven attributes: improvement in pain, improvement in walking, ability to manage domestic activities, ability to manage social activities, improvement in overall energy and well-being, risk of moderate/severe side effects and impact on disease progression. Random parameters logit model w…
The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Pl…
2021
Background: The ISTH Bleeding Assessment Tool (ISTH-BAT) has been validated for clinical screening of suspected von Willebrand disease (VWD) and for bleeding prediction. Recently it has been validated for subjects with inherited platelet disorders (IPD) (BAT-VAL study). Objectives: To determine whether the ISTH-BAT bleeding score (BS) predicts subsequent bleeding events requiring treatment in IPD patients. Methods: Patients with IPD, type 1 VWD (VWD-1) and age- and sex-matched healthy controls enrolled in the BAT-VAL study were prospectively followed-up for 2 years and bleeding episodes requiring treatment were recorded. Results: Of the 1098 subjects initially enrolled, 955 were followed-up…
Impact of Storage Acquisition Intervals on the Cost-Efficiency of the Private vs. Public Storage
2012
The volume of worldwide digital content has increased nine-fold within the last five years, and this immense growth is predicted to continue in foreseeable future reaching 8ZB already by 2015. Traditionally, in order to cope with the growing demand for storage capacity, organizations proactively built and managed their private storage facilities. Recently, with the proliferation of public cloud infrastructure offerings, many organizations, instead, welcomed the alternative of outsourcing their storage needs to the providers of public cloud storage services. The comparative cost-efficiency of these two alternatives depends on a number of factors, among which are e.g. the prices of the public…
Contextual Metadata for Document Databases
2005
Metadata has always been an important means to support accessibility of information in document collections. Metadata can be, for example, bibliographic data manually created for each document at the time of document storage. The indexes created by Web search engines serve as metadata about the content of Web documents. In the semantic Web solutions, ontologies are used to store semantic metadata (Berners-Lee et al., 2001). Attaching a common ontology to a set of heterogeneous document databases may be used to support data integration. Creation of the common ontology requires profound understanding of the concepts used in the databases. It is a demanding task, especially in cases where the …
The sharing of research data in the cell & Tissue engineering area: Is it a common practice?
2018
The availability of research data sets is an important milestone because it can enhance the dynamics of research. This study aims to analyze the PubMed Central repository to determine the availability and type of raw data sets in Cell & Tissue Engineering journals indexed in Journal Citation Reports. The number and types of files were registered. The main finding of this study is that, beyond the mandatory deposit of data in specific repositories that some journals require, the exchange of data as supplementary material in the Cell & Tissue Engineering journals is not a common practice since researchers are still reticent to do so.