Search results for "Research Validity"

showing 10 items of 16 documents

Standardized on-road tests assessing fitness-to-drive in people with cognitive impairments: A systematic review.

2020

Objective The on-road assessment is the gold standard because of its ecological validity. Yet existing instruments are heterogeneous and little is known about their psychometric properties. This study identified existing on-road assessment instruments and extracted data on psychometric properties and usability in clinical settings. Method A systematic review identified studies evaluating standardized on-road evaluation instruments adapted for people with cognitive impairment. Published articles were searched on PubMed, CINHAL, PsycINFO, Web of Science, and ScienceDirect. Study quality and the level of evidence were assessed using the COSMIN checklist. The collected data were synthetized usi…

030506 rehabilitationResearch ValidityPsychometricsEcological validityApplied psychologySocial SciencesTransportationPsycINFO0302 clinical medicineCognitionMedicine and Health SciencesPsychologyCognitive ImpairmentMultidisciplinaryCognitive NeurologyQRResearch AssessmentTransportation InfrastructureTest (assessment)ProfessionsSystematic reviewNeurologyAutomobile Driver ExaminationEngineering and TechnologyMedicine0305 other medical sciencePsychologyResearch ArticleAutomobile DrivingPsychometricsSystematic ReviewsCognitive NeuroscienceScienceResearch and Analysis MethodsCivil Engineering03 medical and health sciencesMental Health and PsychiatryCriterion validityHumansCognitive Dysfunctionbusiness.industryBiology and Life SciencesUsabilityEvidence-based medicineAutomobile Driver Examination; Automobile Driving; Cognitive Dysfunction; Humans; Psychometrics/methodsRoadsInstructorsPeople and PlacesCognitive ScienceDementiaPopulation Groupingsbusiness030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Population-based validation of a German version of the Brief Resilience Scale.

2017

Smith and colleagues developed the Brief Resilience Scale (BRS) to assess the individual ability to recover from stress despite significant adversity. This study aimed to validate the German version of the BRS. We used data from a population-based (sample 1: n = 1.481) and a representative (sample 2: n = 1.128) sample of participants from the German general population (age ≥ 18) to assess reliability and validity. Confirmatory factor analyses (CFA) were conducted to compare one- and two-factorial models from previous studies with a method-factor model which especially accounts for the wording of the items. Reliability was analyzed. Convergent validity was measured by correlating BRS scores …

AdultMaleResearch ValidityAdolescentPsychometricsEmotions610 Medizinlcsh:MedicineSocial SciencesPsychological StressPrincipal component analysis ; Depression ; Anxiety ; Emotions ; Psychological stress ; Religion ; Mental health and psychiatry ; PsychometricsModels PsychologicalResearch and Analysis MethodsCultural AnthropologyYoung AdultMathematical and Statistical TechniquesSociology610 Medical sciencesGermanyMental Health and PsychiatryMedicine and Health SciencesHumansPsychologyStatistical Methodslcsh:ScienceAgedAged 80 and overPrincipal Component AnalysisMood DisordersDepressionlcsh:RBiology and Life SciencesMiddle AgedResilience PsychologicalResearch AssessmentReligionAnthropologyBehavior Rating ScaleMultivariate AnalysisPhysical Scienceslcsh:QFemaleMathematicsStatistics (Mathematics)Research ArticlePloS one
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The anisotropy of personal space.

2019

Violations of personal space are associated with discomfort. However, the exact function linking the magnitude of discomfort to interpersonal distance has not yet been specified. In this study, we explore whether interpersonal distance and discomfort are isotropic with respect to uncomfortably far or close distances. We also extend previous findings with regard to intrusions into personal space as well as maintenance of distances outside of personal space. We presented subjects with 15 interpersonal distances ranging from 40 to 250 cm and obtained verbal and joystick-based ratings of discomfort. Whereas discomfort rose immediately when personal space was entered, the gradient was less steep…

AdultMaleResearch ValidityTopographyScienceMaterials ScienceMaterial PropertiesEmotionsSocial SciencesResearch and Analysis MethodsStatistical InferencePersonal SpaceYoung AdultMathematical and Statistical TechniquesTask Performance and AnalysisPsychologyHumansStatistical MethodsStatistical DataAnalysis of VarianceLandformsBehaviorPhysicsStatisticsQRBiology and Life SciencesReproducibility of ResultsGeomorphologyFearResearch AssessmentMiddle AgedCondensed Matter Physics150 PsychologiePhysical SciencesEarth SciencesAnisotropyMedicineFemale150 PsychologyMathematicsResearch ArticleValleysPLoS ONE
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Minimization of childhood maltreatment is common and consequential: results from a large, multinational sample using the childhood trauma questionnai…

2016

Childhood maltreatment has diverse, lifelong impact on morbidity and mortality. The Childhood Trauma Questionnaire (CTQ) is one of the most commonly used scales to assess and quantify these experiences and their impact. Curiously, despite very widespread use of the CTQ, scores on its Minimization-Denial (MD) subscale-originally designed to assess a positive response bias-are rarely reported. Hence, little is known about this measure. If response biases are either common or consequential, current practices of ignoring the MD scale deserve revision. Therewith, we designed a study to investigate 3 aspects of minimization, as defined by the CTQ's MD scale: 1) its prevalence; 2) its latent struc…

Child abuseMaleResearch ValidityPsychometrics150Social Scienceslcsh:MedicineDenial PsychologicalCriminology600 Technik Medizin angewandte Wissenschaften::610 Medizin und GesundheitInfographicsPediatricsNational comorbidity survey; Adult psychiatric-disorders; Form CTQ-SF; Psychometric properties; Household dysfunction; German Version; Life stress; Abuse; Reliability; ValiditySHORT FORM0302 clinical medicineSociologySurveys and QuestionnairesMedicine and Health SciencesPsychologyPublic and Occupational HealthDenial (Psychology)Child AbuseGERMAN VERSIONChildlcsh:Sciencemedia_commonViolence ResearchPediatricPsychiatryMultidisciplinaryIncidence (epidemiology)Child HealthResearch AssessmentHOUSEHOLD DYSFUNCTIONDisorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]SuicideMental HealthDenialADULT PSYCHIATRIC-DISORDERSScale (social sciences)RELIABILITYchild; childhood; Childhood Trauma Questionnaire; dependent variable; human; human tissue; major clinical study; mental patient; prevalence; scientist; validity; volunteerFemaleCrimeGraphsMedicine; PsychiatryResearch Articlemedicine.medical_specialtyComputer and Information SciencesPsychometricsGeneral Science & Technologymedia_common.quotation_subjectMEDLINEPsychological Stress610Sample (statistics)Research and Analysis MethodsPsykiatri03 medical and health sciencesDenialClinical ResearchMental Health and PsychiatryADVERSITYmedicineHumansVALIDITYPsychiatryABUSEPsychiatric Status Rating Scalesbusiness.industryData Visualizationlcsh:RCTQ treeBiology and Life Sciences030227 psychiatryHealth Care100 Philosophie und Psychologie::150 PsychologiePSYCHOMETRIC PROPERTIESCTQPsychologicallcsh:QHealth StatisticsMorbiditybusiness030217 neurology & neurosurgeryPLOS ONE
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Testing and comparing two self-care-related instruments among older Chinese adults

2017

Objectives The study aimed to test and compare the reliability and validity, including sensitivity and specificity of the two self-care-related instruments, the Self-care Ability Scale for the Elderly (SASE), and the Appraisal of Self-care Agency Scale-Revised (ASAS-R), among older adults in the Chinese context. Methods A cross-sectional design was used to conduct this study. The sample consisted of 1152 older adults. Data were collected by a questionnaire including the Chinese version of SASE (SASE-CHI), the Chinese version of ASAS-R (ASAS-R-CHI) and the Exercise of Self-Care Agency scale (ESCA). Homogeneity and stability, content, construct and concurrent validity, and sensitivity and spe…

GerontologyMaleAgingResearch ValidityPhysiologylcsh:MedicineGeographical LocationsHabitsElderlySurveys and QuestionnairesStatisticsContent validityMedicine and Health SciencesMedicineEthnicitieslcsh:ScienceGeriatricsCognitive ImpairmentAged 80 and overMultidisciplinary030504 nursingCognitive Neurology030503 health policy & servicesResearch AssessmentMiddle AgedNeurologyFemale0305 other medical scienceResearch Articlemedicine.medical_specialtyChinaAsiaCorrelation coefficientPsychometricsCognitive NeuroscienceConcurrent validityResearch and Analysis MethodsSensitivity and Specificity03 medical and health sciencesCronbach's alphaHumansRank correlationAgedBehaviorReceiver operating characteristicbusiness.industrylcsh:RConstruct validityBiology and Life SciencesReproducibility of ResultsSelf CareCross-Sectional StudiesAge GroupsGeriatricsPeople and PlacesCognitive Sciencelcsh:QPopulation GroupingsbusinessPhysiological ProcessesOrganism DevelopmentChinese PeopleNeuroscienceDevelopmental BiologyPLoS ONE
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Validation of two portable bioelectrical impedance analyses for the assessment of body composition in school age children

2017

Background Bioelectrical impedance analysis (BIA) is a convenient and child-friendly method for longitudinal analysis of changes in body composition. However, most validation studies of BIA have been performed on adult Caucasians. The present cross-sectional study investigated the validity of two portable BIA devices, the Inbody 230 (BIA8MF) and the Tanita BC-418 (BIA8SF), in healthy Taiwanese children. Methods Children aged 7–12 years (72 boys and 78 girls) were recruited. Body composition was measured by the BIA8SF and the BIA8MF. Dual X-ray absorptiometry (DXA) was used as the reference method. Results There were strong linear correlations in body composition measurements between the BIA…

MalePediatricsResearch ValidityCross-sectional studylcsh:MedicinePediatricsDiagnostic RadiologyFamilies0302 clinical medicineMathematical and Statistical TechniquesAbsorptiometry PhotonMedicine and Health SciencesElectric ImpedanceMedicine030212 general & internal medicinelcsh:ScienceChildChildrenMusculoskeletal SystemMultidisciplinarySchool age childRadiology and ImagingLimits of agreementResearch AssessmentArmsConcordance correlation coefficientArticle-Level MetricsAdipose TissuePhysical SciencesBody CompositionRegression AnalysisFemaleAnatomyBioelectrical impedance analysisStatistics (Mathematics)Research Articlemedicine.medical_specialtyImaging Techniques030209 endocrinology & metabolismLinear Regression AnalysisResearch and Analysis MethodsFat mass03 medical and health sciencesDiagnostic MedicineLinear regressionHumansAbsorptiometryStatistical MethodsAltmetricsbusiness.industrylcsh:RLimbs (Anatomy)Biology and Life SciencesReproducibility of ResultsBiological TissueCross-Sectional StudiesAge GroupsPeople and PlacesLean body masslcsh:QPopulation GroupingsbusinessNuclear medicineMathematicsPLoS ONE
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Psychometric Assessment of the Japanese Version of the Zurich Claudication Questionnaire (ZCQ): Reliability and Validity.

2016

Purpose The Zurich Claudication Questionnaire (ZCQ) is a self-administered measure to evaluate symptom severity, physical function, and surgery satisfaction in lumbar spinal stenosis (LSS). The purpose of this study is to assess the psychometric properties of the Japanese ZCQ in LSS patients. Methods LSS patients who are scheduled to undergo surgery were recruited from 12 facilities. Responses to several questionnaires, including the Japanese ZCQ; the visual analogue scale (VAS) to evaluate the degree of pain in the buttocks/legs, numbness in the buttocks/legs, and low back pain; the Oswestry Disability Index (ODI); and the SF-36v2, were collected before surgery and again 3 months after sur…

MaleQuestionnairesResearch ValidityPsychometricsSocial Scienceslcsh:MedicinePathology and Laboratory Medicine0302 clinical medicineSpinal StenosisJapanSurveys and QuestionnairesMedicine and Health SciencesPsychology030212 general & internal medicinelcsh:ScienceMusculoskeletal SystemStenosisMultidisciplinaryLumbar VertebraeMiddle AgedResearch AssessmentLow back painOswestry Disability IndexPatient SatisfactionResearch DesignLegsFemalemedicine.symptomAnatomyResearch Articlemedicine.medical_specialtyPsychometricsVisual analogue scaleConcurrent validityLower Back PainPainSurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesPatient satisfactionPhysical medicine and rehabilitationSigns and SymptomsCronbach's alphaDiagnostic MedicineMental Health and PsychiatrymedicineHumansAgedSurvey Researchbusiness.industryLimbs (Anatomy)lcsh:RBiology and Life SciencesPhysical therapylcsh:QbusinessClaudication030217 neurology & neurosurgeryPLoS ONE
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The assessment of successful emotion regulation skills use: Development and validation of an English version of the Emotion Regulation Skills Questio…

2018

Emotion regulation has become an important topic in mental health and psychotherapy research. Skills supposingly relevant for adaptive responses towards emotions include the abilities to be consciously aware of emotions, identify and correctly label emotions, understand what has caused and maintains one's present emotions, modify the intensity or duration of one's emotions, accept and tolerate undesired emotions, confront situations likely to cue negative emotions, and provide effective self-support when working to cope with challenging emotions. To economically assess these abilities, a self-report measure has been developed in German and validated in various studies. To facilitate the use…

MaleResearch Validity050103 clinical psychologyPsychometricsEmotionsApplied psychologylcsh:MedicineSocial SciencesTest validityAnxietyMathematical and Statistical Techniques0302 clinical medicineddc:150Adaptation PsychologicalMedicine and Health SciencesPsychologylcsh:ScienceEmotional Intelligencemedia_commonMultidisciplinaryDepressionMental DisordersStatistics05 social sciencesSelf-controlResearch AssessmentMiddle AgedPhysical SciencesFemalePsychologyFactor AnalysisResearch ArticleAdultPsychometricsAdolescentmedia_common.quotation_subjectPsychological Stress-Philosophische Fakultät und Fachbereich TheologieModels PsychologicalResearch and Analysis MethodsSelf-ControlSocial SkillsYoung Adult03 medical and health sciencesSocial skillsMental Health and PsychiatryHumans0501 psychology and cognitive sciencesPsychological testingStatistical MethodsAdaptation (computer science)Psychological TestsMood DisordersEmotional intelligencelcsh:RBiology and Life SciencesTranslatingMental health030227 psychiatrylcsh:QSelf ReportMathematicsPLOS ONE
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Reliability of a new analysis to compute time to stabilization following a single leg drop jump landing in children.

2019

Although a number of different methods have been proposed to assess the time to stabilization (TTS), none is reliable in every axis and no tests of this type have been carried out on children. The purpose of this study was thus to develop a new computational method to obtain TTS using a time-scale (frequency) approach [i.e. continuous wavelet transformation (WAV)] in children. Thirty normally-developed children (mean age 10.16 years, SD = 1.52) participated in the study. Every participant performed 30 single-leg drop jump landings with the dominant lower limb (barefoot) on a force plate from three different heights (15cm, 20cm and 25cm). Five signals were used to compute the TTS: i) Raw, ii…

MaleResearch ValidityMuscle PhysiologyTime FactorsPhysiologyIntraclass correlationPolynomialsSignalRoot mean square0302 clinical medicineContinuous waveletStatisticsMedicine and Health SciencesBiomechanicsChildMusculoskeletal SystemReliability (statistics)MathematicsSignal processingMultidisciplinaryQRResearch AssessmentBiomechanical PhenomenaSignal FilteringPhysiological ParametersPhysical SciencesEngineering and TechnologyLegsMedicineFemaleAnatomyResearch ArticleMovementScienceResearch and Analysis Methods03 medical and health sciencesHumansMechanical PhenomenaLegBody WeightBiology and Life SciencesReproducibility of Results030229 sport sciencesAlgebraTransformation (function)Standard errorBody LimbsSignal ProcessingMusculoskeletal MechanicsMathematics030217 neurology & neurosurgeryPLoS ONE
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Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

2012

The Bcr/Abl kinase has been targeted for the treatment of chronic myelogenous leukaemia (CML) by imatinib mesylate. While imatinib has been extremely effective for chronic phase CML, blast crisis CML are often resistant. New therapeutic options are therefore needed for this fatal disease. Although more common in solid tumors, increased microvessel density was also reported in chronic myelogenous leukaemia and was associated with a significant increase of angiogenic factors, suggesting that vascularity in hematologic malignancies is a controlled process and may play a role in the leukaemogenic process thus representing an alternative therapeutic target. Carboxyamidotriazole-orotate (CTO) is …

MaleResearch ValidityPhysiologyAngiogenesisTumor PhysiologyFusion Proteins bcr-ablCancer Treatmentlcsh:MedicinePharmacologyExosomesCardiovascular PhysiologyBiochemistryPiperazinesHematologic Cancers and Related DisordersMicechemistry.chemical_compoundCell Movementhemic and lymphatic diseasesMolecular Cell BiologyBasic Cancer ResearchMedicine and Health SciencesPhosphorylationPost-Translational ModificationExtracellular Signal-Regulated MAP Kinaseslcsh:ScienceChronic Myelogenous LeukemiaMultidisciplinaryABLNeovascularization PathologicGene Expression Regulation LeukemicChemistryHematologyResearch AssessmentOncologyBenzamidesImatinib MesylateMedicineOncology AgentsAntiangiogenesis Therapymedicine.drugResearch ArticleChronic Myeloid LeukemiaAntineoplastic AgentsResearch and Analysis MethodsCell GrowthCell Line TumorLeukemia Myelogenous Chronic BCR-ABL PositiveLeukemiasCell AdhesionHuman Umbilical Vein Endothelial CellsmedicineAnimalsHumansRNA MessengerPhosphotyrosineBiologyCell ProliferationOrotic AcidTumor microenvironmentCarboxyamidotriazoleInterleukin-8lcsh:RBiology and Life SciencesProteinsCancers and NeoplasmsImatinibTriazolesmedicine.diseaseXenograft Model Antitumor AssaysRetractionExosomePyrimidinesImatinib mesylateDrug Resistance NeoplasmCarboxyamidotriazole Orotatelcsh:QAngiogenesisCell Adhesion MoleculesProto-Oncogene Proteins c-aktDevelopmental BiologyChronic myelogenous leukemiaPLoS ONE
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