Search results for "Result"

showing 10 items of 2426 documents

Distribution of sea urchins living near shallow water CO2 vents is dependent upon species acid-base and ion-regulatory abilities.

2013

To reduce the negative effect of climate change on Biodiversity, the use of geological CO2 sequestration has been proposed; however leakage from underwater storages may represent a risk to marine life. As extracellular homeostasis is important in determining species' ability to cope with elevated CO2, we investigated the acid-base and ion regulatory responses, as well as the density, of sea urchins living around CO2 vents at Vulcano, Italy. We conducted in situ transplantation and field-based laboratory exposures to different pCO2/pH regimes. Our results confirm that sea urchins have some ability to regulate their extracellular fluid under elevated pCO2. Furthermore, we show that even in cl…

0106 biological sciencesSettore BIO/07 - EcologiaGeological Phenomena010504 meteorology & atmospheric sciencesClimate ChangeSpecies distributionBiodiversityMarine lifeAquatic ScienceOceanography01 natural sciencesParacentrotus lividushowever leakage from underwater storages may represent a risk to marine life. As extracellular homeostasis is important in determining species' ability to cope with elevated CO2 we investigated the acid-base and ion regulatory responses as well as the density of sea urchins living around CO2 vents at Vulcano Italy. We conducted in situ transplantation and field-based laboratory exposures to different pCO2/pH regimes. Our results confirm that sea urchins have some ability to regulate their extracellular fluid under elevated pCO2. Furthermore we show that even in closely-related taxa divergent physiological capabilities underlie differences in taxa distribution around the CO2 vent. It is concluded that species distribution under the sort of elevated CO2 conditions occurring with leakages from geological storages and future ocean acidification scenarios may partly be determined by quite subtle physiological differentiation.Mediterranean seaBenthosAnimalsSeawater14. Life underwaterEcosystem0105 earth and related environmental sciencesbiologyEcology010604 marine biology & hydrobiologyTo reduce the negative effect of climate change on Biodiversity the use of geological CO2 sequestration has been proposedOcean acidificationCarbon DioxideHydrogen-Ion Concentrationbiology.organism_classificationAdaptation PhysiologicalPollutionTransplantationOceanographyItaly13. Climate actionSea UrchinsWater Pollutants Chemical
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A validity and reliability study of Conditional Entropy Measures of Pulse Rate Variability

2019

In this work, we present the feasibility to use a simpler methodological approach for the assessment of the short-term complexity of Heart Rate Variability (HRV). Specifically, we propose to exploit Pulse Rate Variability (PRV) recorded through photoplethysmography in place of HRV measured from the ECG, and to compute complexity via a linear Gaussian approximation in place of the standard model-free methods (e.g., nearest neighbor entropy estimates) usually applied to HRV. Linear PRV-based and model-free HRV-based complexity measures were compared via statistical tests, correlation analysis and Bland-Altman plots, demonstrating an overall good agreement. These results support the applicabil…

020205 medical informaticsComputer scienceEntropy0206 medical engineeringValidity02 engineering and technologySettore ING-INF/01 - ElettronicaElectrocardiographyPulse Rate Variability (PRV)Heart RatePhotoplethysmogram0202 electrical engineering electronic engineering information engineeringHumansEntropy (information theory)Heart rate variabilityEntropy (energy dispersal)Time seriesPhotoplethysmographyEntropy (arrow of time)Statistical hypothesis testingConditional entropyEntropy (statistical thermodynamics)Reproducibility of ResultsHeart Rate Variability (HRV)020601 biomedical engineeringSettore ING-INF/06 - Bioingegneria Elettronica E InformaticacomplexityAlgorithmEntropy (order and disorder)2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
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Antimicrobial photodynamic therapy using diode laser activated indocyanine green as an adjunct in the treatment of chronic periodontitis: A randomize…

2016

Abstract Introduction Clinical studies have shown the usefulness of antimicrobial photodynamic therapy (aPDT) as an adjunctive in periodontal therapy. These studies did not utilize indocyanine green (ICG) as a recently introduced photosensitizer. The aim of this study was to perform a full-mouth double-blind randomized controlled clinical study to test the efficacy of adjunctive aPDT with ICG compared with scaling and root planing (SRP) alone in chronic periodontitis treatment. Materials and methods Fifty patients were selected for this study. All patients received SRP. Then, each patient was randomly assigned to either the test group (aPDT + SRP) or the control group (SRP). aPDT was perfor…

0301 basic medicineAdultIndocyanine GreenMale030103 biophysicsGingival and periodontal pocketmedicine.medical_treatmentBleeding on probingBiophysicsDentistryPhotodynamic therapyDermatologylaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicineScaling and root planingRandomized controlled triallawmedicineHumansPharmacology (medical)Photosensitizing Agentsbusiness.industryReproducibility of Results030206 dentistryMiddle AgedReference Standardsmedicine.diseaseChronic periodontitisOncologychemistryClinical attachment lossPhotochemotherapyChronic PeriodontitisFemalemedicine.symptomLasers SemiconductorbusinessIndocyanine greenPhotodiagnosis and photodynamic therapy
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Measuring Orthorexia Nervosa: Psychometric Limitations of the ORTO-15.

2017

AbstractOrthorexia nervosa has recently been defined as excessive preoccupation with healthy eating, causing significant nutritional deficiencies and social and personal impairments. The ORTO-15 is the most widely used instrument to evaluate orthorexia nervosa, although previous studies obtained inconsistent results about its psychometric properties, and there are no data on the Spanish version. Thus, the main objective of the present study was to analyze the psychometric properties of the Spanish adaptation of the ORTO-15. In order to cross-validate the results, two independent samples were used (Sample 1: n = 807, 74.1% women; Sample 2: n = 242, 63.2% women). The results did not support t…

0301 basic medicineAdultMale050103 clinical psychologyLinguistics and LanguagePsychometricsHealth BehaviorHealthy eatingLanguage and LinguisticsDevelopmental psychologyFeeding and Eating Disorders03 medical and health sciencesYoung AdultInternal consistencyIndependent samplesmedicineHumans0501 psychology and cognitive sciencesGeneral PsychologyOrthorexia nervosaPsychiatric Status Rating Scales030109 nutrition & dietetics05 social sciencesReproducibility of ResultsSpanish versionmedicine.diseaseSpainFemalePsychologyPsychopathologyThe Spanish journal of psychology
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Acoustic radiation force impulse point shear wave elastography of the liver and spleen in patients with Gaucher disease type 1: Correlations with cli…

2020

To evaluate the feasibility of acoustic radiation force impulse point shear wave elastography (ARFI-pSWE) of the liver and spleen in patients with Gaucher disease type 1 (GD1), and to assess correlations between organ stiffness and clinico-radiologic data, particularly the GD1 Severity Scoring System (GD-DS3).We retrospectively evaluated the results of ARFI-pSWE as measures of liver and spleen stiffness in 57 patients with GD1. The feasibility of the method was assessed. Correlations between elastography data and clinical data related to the metabolic syndrome, laboratory tests, and GD1-related clinico-radiologic data (bone marrow burden score, GD-DS3) were assessed.ARFI-pSWE provided relia…

0301 basic medicineAdultMalemedicine.medical_specialtyAdolescentEndocrinology Diabetes and MetabolismSpleenDisease030105 genetics & heredityImpulse (physics)BiochemistrySeverity of Illness Index03 medical and health sciencesYoung Adult0302 clinical medicineEndocrinologyGeneticsmedicineHumansIn patientAcoustic radiation forceChildMolecular BiologyAgedRetrospective StudiesGaucher Diseasemedicine.diagnostic_testbusiness.industryReproducibility of ResultsAcousticsMiddle Agedmedicine.diseasePrognosismedicine.anatomical_structureLiverChild PreschoolElasticity Imaging TechniquesFemaleElastographyBone marrowRadiologyMetabolic syndromebusiness030217 neurology & neurosurgeryBiomarkersSpleenFollow-Up StudiesMolecular genetics and metabolism
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Long-term outcomes and predictive ability of non-invasive scoring systems in patients with non-alcoholic fatty liver disease.

2021

[Background & Aims] Non-invasive scoring systems (NSS) are used to identify patients with non-alcoholic fatty liver disease (NAFLD) who are at risk of advanced fibrosis, but their reliability in predicting long-term outcomes for hepatic/extrahepatic complications or death and their concordance in cross-sectional and longitudinal risk stratification remain uncertain.

0301 basic medicineAdultMalemedicine.medical_specialtyCirrhosisConcordanceSettore MED/12 - GASTROENTEROLOGIAHFSDiseaseBARDGastroenterologySeverity of Illness IndexTime03 medical and health sciences0302 clinical medicineFibrosisNon-alcoholic Fatty Liver DiseasePredictive Value of TestsInternal medicineNFSmedicineHumansIn patientAPRINSSHepatologybusiness.industryFatty liverNASHReproducibility of ResultsMiddle Agedmedicine.diseasePrognosisAPRI BARD FIB-4 HFS NASH NFS NSS Adult Area Under Curve Cross-Sectional Studies Female Humans Liver MaleMiddle Aged Non-alcoholic Fatty Liver DiseasePrognosis ROC CurveReproducibility of Results Research Design Severity of Illness Index Predictive Value of Tests Time030104 developmental biologyCross-Sectional StudiesLiverROC CurveResearch DesignArea Under CurveCohortAPRI; BARD; FIB-4; HFS; NASH; NFS; NSSFIB-4030211 gastroenterology & hepatologyFemalebusinessLiver cancerJournal of hepatology
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Incidental findings in a series of 2500 gene panel tests for a genetic predisposition to cancer: Results and impact on patients.

2020

Abstract With next generation sequencing, physicians are faced with more complex and uncertain data, particularly incidental findings (IF). Guidelines for the return of IF have been published by learned societies. However, little is known about how patients are affected by these results in a context of oncogenetic testing. Over 4 years, 2500 patients with an indication for genetic testing underwent a gene cancer panel. If an IF was detected, patients were contacted by a physician/genetic counsellor and invited to take part in a semi-structured interview to assess their understanding of the result, the change in medical care, the psychological impact, and the transmission of results to the f…

0301 basic medicineAdultMalemedicine.medical_specialtyPatientsContext (language use)030105 genetics & heredity03 medical and health sciencesNeoplasmsGeneticsmedicineGenetic predispositionHumansGenetic Predisposition to DiseaseGenetic TestingCHEK2Genetics (clinical)Genetic testingAgedIncidental Findingsmedicine.diagnostic_testbusiness.industryCancerRegretGeneral MedicineMiddle Agedmedicine.disease030104 developmental biologyAttitudeFamily medicineAnxietyFemalemedicine.symptomReturn of resultsbusinessEuropean journal of medical genetics
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Peripapillary fluorescence lifetime reveals age-dependent changes using fluorescence lifetime imaging ophthalmoscopy in rats

2017

Abstract Many fundus diseases accompany fundus autofluorescence change. Fluorescence lifetime imaging ophthalmoscope (FLIO) is a latest technique in imaging fundus autofluorescence. With FLIO, the fundus fluorescence lifetime (FLT) is recorded topographically, assisting to diagnose and monitor multiple fundus diseases. The purpose of this study was to evaluate the repeatability of FLT using FLIO on adult rats and to analyze the age-dependency of the peripapillary FLT of the fundus in a short spectral channel (498–560 nm) and a long spectral channel (560–720 nm). Sprague Dawley rats (n of eyes = 10) were used for repeatability experiments. Age-dependent changes were investigated in young (tw…

0301 basic medicineAgingmedicine.medical_specialtyFluorescence-lifetime imaging microscopygenetic structuresFundus OculiOptic DiskAge dependentFundus (eye)FluorescenceRetinaRats Sprague-DawleyOphthalmoscopy03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineOphthalmologySprague dawley ratsAnimalsMedicineFluorescein Angiographymedicine.diagnostic_testbusiness.industryReproducibility of ResultsRepeatabilityFluorescenceeye diseasesSensory SystemsFundus autofluorescenceRatsOphthalmoscopyOphthalmology030104 developmental biologyModels Animal030221 ophthalmology & optometryFemalesense organsbusinessExperimental Eye Research
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Transferability of PCR-based diagnostic protocols: An international collaborative case study assessing protocols targeting the quarantine pine pathog…

2019

Producción Científica

0301 basic medicineAgricultural BiotechnologyPerformanceInternational Cooperation1ST REPORTlcsh:Medicinediagnostica PCR protocolli PCR trasferibilità patologia forestale patogeni fungini fusarium circinatum malattie emergenti / PCR diagnostics protocol transferability emerging tree diseases fungal forest pathogensPolymerase Chain ReactionPine pitch cankerlaw.invention0302 clinical medicineFusariumlawChancro resinoso del pinoFalse positive paradoxDNA Fungallcsh:SciencePathogenPolymerase chain reactionPinus radiataEnfermedades fúngicas - DiagnósticoMultidisciplinaryAgricultural SciencesCausal agentPathogenic fungusPitch Canker disease3. Good healthOther Agricultural SciencesTests PCRGibberella-CircinataFusariumPolymerase-Chain-ReactionDNA PlantPlantationsBOTANICATransferabilityFusarium circinatumBiologyPitch cankerno key wordsReal-Time Polymerase Chain ReactionSensitivity and SpecificityArticleREAL-TIME PCR; POLYMERASE-CHAIN-REACTION; PITCH CANKER DISEASE; CAUSAL AGENT; GIBBERELLA-CIRCINATA; 1ST REPORT; QUANTIFICATION; SUSCEPTIBILITY; PLANTATIONS; PERFORMANCE03 medical and health sciencesGibberella circinataQuantificationQuarantineDiagnóstico de enfermedad fungicaFalse Positive ReactionsFungal infections - DiagnosisMolecular BiologyPlant DiseasesInvasive speciesbusiness.industrylcsh:RReproducibility of ResultsPinusbiology.organism_classificationPCR-based testsBiotechnology030104 developmental biology3106 Ciencia ForestalSusceptibilitylcsh:QReal-Time PCRbusinessPCR-based techniques030217 neurology & neurosurgeryScientific Reports
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Identification of Candida auris and related species by multiplex PCR based on unique GPI protein‐encoding genes

2020

Background The pathogen Candida auris is rapidly gaining clinical importance because of its resistance to antifungal treatments and its persistence in hospital environments. Early and accurate diagnosis of C. auris infections is crucial, however, the fungus has often been misidentified by commercial systems. Objectives To develop conventional and real-time PCR methods for accurate and rapid identification of C. auris and its discrimination from closely related species by exploiting the uniqueness of certain glycosylphosphatidylinositol-modified protein-encoding genes. Methods Species-specific primers for two unique putative GPI protein-encoding genes per species were designed for C. auris, …

0301 basic medicineAntifungal AgentsGlycosylphosphatidylinositolsGenes Fungal030106 microbiologyDermatologyBiologyReal-Time Polymerase Chain ReactionFungal Proteins030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineSpecies SpecificityMultiplex polymerase chain reactionHumansMultiplexMycological Typing TechniquesGenePathogenCandidaDNA PrimersGeneticsCandidiasisReproducibility of ResultsGeneral MedicineAmpliconCorpus albicansInfectious DiseasesCandida aurisIndansIdentification (biology)Multiplex Polymerase Chain ReactionMycoses
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