Search results for "Riba"
showing 10 items of 371 documents
Boceprevir is highly effective in treatment-experienced hepatitis C virus-positive genotype-1 menopausal women
2014
AIM: To investigate the safety/efficacy of Boceprevirbased triple therapy in hepatitis C virus (HCV)-G1 menopausal women who were historic relapsers, partial-responders and null-responders. METHODS: In this single-assignment, unblinded study, we treated fifty-six menopausal women with HCV-G1, 46% F3-F4, and previous PEG-α/RBV failure (7% null, 41% non-responder, and 52% relapser) with 4 wk lead-in with PEG-IFNα2b/RBV followed by PEGIFNα2b/RBV+Boceprevir for 32 wk, with an additional 12 wk of PEG-IFN-α-2b/RBV if patients were HCV-RNA-positive by week 8. In previous null-responders, 44 wk of triple therapy was used. The primary objective of retreatment was to verify whether a sustained virolo…
"Fabula narratur toto notissima caelo": "cornuto" e cornuti nel "Gattopardo"
2019
In Il Gattopardo of Giuseppe Tomasi di Lampedusa there are three cuckolds: Vulcan, Giuseppe Garibaldi, and Tancredi Falconeri. This study explains how this triad is constituted and shows how the three figures are related in the narrative. The analysis opens a new perspective on the interpretation of the novel and brings out some aspects of its implicit organization.
Efficacy of the retreatment of hepatitis C virus infections after liver transplantation: Role of an aggressive approach
2012
A sustained virological response (SVR) is achieved by 30% of naive liver transplantation (LT) recipients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV). Almost no data are available about retreatment. The aim of this study was to assess the efficacy, tolerability, and SVR predictors of retreatment. Data were collected from 4 centers on the retreatment of prior nonresponders to standard therapy or PEG-IFN (with or without RBV) and relapsers. Seventy-nine of 301 treatment-experienced LT patients (26%), who had a median age of 59 years (range = 35-77 years) and were mostly male (72%) and infected with genotype 1 (87%), were retreated with PEG-IFN and RBV at a median of 6.9 yea…
Anemia is not predictive of sustained virological response in liver transplant recipients with hepatitis C virus who are treated with pegylated inter…
2011
In the immunocompetent setting, antiviral therapy–related anemia has recently been shown to be associated with a sustained virological response (SVR). Our goal was to assess whether this is also true for liver transplantation (LT). We included 160 LT patients with recurrent hepatitis C virus (HCV) who were treated with pegylated interferon and ribavirin (RBV) between 2002 and 2010; 76% of the patients were men, the median age of the patients was 56 years (range = 33-75 years), 63% had advanced fibrosis, and 86% were infected with HCV genotype 1a or 1b. The baseline immunosuppression was tacrolimus in 56% of the patients. Mycophenolate mofetil (MMF) was used in 15%. Anemia was defined as a h…
A new species of <em>Metapyroppia</em> Woolley, 1969 (Acari, Oribatida, Peloppiidae) from Nepal
2014
A new species of oribatid mites of the family Peloppiidae, Metapyroppia gigantea n. sp. , is described from Nepal. The genus Metapyroppia is recorded for the first time from the Oriental region. Metapyroppia gigantea n. sp. differs from the type species, Metapyroppia doratosa Woolley, 1969, by the absence of notogastral setae c 2 and c 3 , presence of pointed rostrum and the adanal lyrifissures distanced from the anal plates. The morphology of gnathosoma and legs are presented in detail for the first time for any member of this genus. urn:lsid:zoobank.org:pub:EEE741F4-4C86-4625-B3FD-48E1DDA1D2D3
Tumoresferas como plataformas de cribado farmacológico in vitro/in vivo para la búsqueda de nuevas terapias contra el cáncer de pulmón no microcítico
2020
El cáncer de pulmón es el tumor con mayor mortalidad a nivel mundial, y en concreto el cáncer de pulmón no microcítico (CPNM) comprende más del 80% de los casos. Actualmente, los fármacos más empleados en este tipo de cáncer son los quimioterápicos; sin embargo, la adquisición de resistencia a estos compuestos limita en gran medida la eficacia de los tratamientos. Dentro de las diferentes poblaciones celulares presentes en el microambiente tumoral se encuentran las células madre tumorales (CMTs), encargadas de la proliferación y diferenciación, estas células tienen capacidad de latencia y poca respuesta a los tratamientos empleados actualmente en la práctica clínica, por tanto, responsables…
Con la mayor hermosura y arte: Pinturas de Juan Ribalta para los condes de Aranda
2013
El presente artículo trata sobre algunos aspectos del mecenazgo llevado a cabo por los Condes de Aranda en la ciudad de Épila (Zaragoza). Se abordan temas relacionados con la fundación del Monasterio de la Purísima Concepción y la participación del pintor Juan Ribalta (Madrid, ca. 1596 – Valencia, 1629) en la decoración del retablo mayor. Del mismo modo, también se aborda el estudio del importante conjunto de pinturas de temática franciscana que allí se conservan, el último gran encargo realizado por Juan Ribalta antes de su prematura muerte. This article discusses some aspects of patronage held by the Counts of Aranda in the city of Épila (Zaragoza). It also examines certain issues related…
Los escribanos de Ramón Berenguer IV: nuevos datos
1979
Notarios y escribanos de Alfonso II (1154-1196): datos biográficos
1978
Un documento señorial de nombramiento de escribano en Castilla. 1517
1984
EL PRESENTE ESTUDIO PRESENTA Y ANALIZA UN DOCUMENTO QUE PERMITE EXPLICAR EL PROCESO DE NOMBRAMIENTO DE ESCRIBANOS SEÑORIALES. APORTA ADEMAS, UN BREVE PERO SIGNIFICATIVO EXAMEN DE LOS ACONTECIMIENTOS HISTORICOS Y JURIDICOS QUE HACEN POSIBLE LA EMANACION DE DICHO DOCUMENTO, EL CUAL A SU VEZ ES SOMETIDO A UN RIGUROSO EXAMEN DIPLOMATICO.