Search results for "Ridge"
showing 10 items of 531 documents
Vascular Senescence: A Potential Bridge Between Physiological Aging and Neurogenic Decline
2021
The adult mammalian brain contains distinct neurogenic niches harboring populations of neural stem cells (NSCs) with the capacity to sustain the generation of specific subtypes of neurons during the lifetime. However, their ability to produce new progeny declines with age. The microenvironment of these specialized niches provides multiple cellular and molecular signals that condition NSC behavior and potential. Among the different niche components, vasculature has gained increasing interest over the years due to its undeniable role in NSC regulation and its therapeutic potential for neurogenesis enhancement. NSCs are uniquely positioned to receive both locally secreted factors and adhesion-…
Desmoplastic fibroblastoma (collagenous fibroma) of the oral cavity
2016
Desmoplastic fibroblastoma is benign soft tissue tumor, with fibroblastic or myofibroblastic origin, that rarely occurs in oral cavity. We reported the case of a 56-year-old man who presented a tumor in the left mandibular alveolar ridge, with slow and asymptomatic growth, with no osseous involvement. The tumor was sessile with lobulated surface, covered by healthy mucosa with erythematous areas. The lesion was excised and specimens sent to histopathology and immunohistochemistry. Histopathological exam showed a non-encapsulated fibroblastic proliferation, characterized by myofibroblasts, spindle and stellate fibroblasts with large or oval nuclei and bi or tri nucleation, immersed in an abu…
Self-normalized and randomly centered spectral estimates
1996
We review some limit theory for the periodogram and for integrated versions of it and explain the use of random normalizing and centering techniques.
Steady states and nonlinear buckling of cable-suspended beam systems
2018
This paper deals with the equilibria of an elastically-coupled cable-suspended beam system, where the beam is assumed to be extensible and subject to a compressive axial load. When no vertical load is applied, necessary and sufficient conditions in order to have nontrivial solutions are established, and their explicit closed-form expressions are found. In particular, the stationary solutions are shown to exhibit at most two non-vanishing Fourier modes and the critical values of the axial-load parameter which produce their pitchfork bifurcation (buckling) are established. Depending on two dimensionless parameters, the complete set of resonant modes is devised. As expected, breakdown of the p…
Antibacterial Activity and Anticancer Activity of Rosmarinus officinalis L. Essential Oil Compared to That of Its Main Components
2012
In this study, Rosmarinus officinalis L. essential oil and three of its main components 1,8-cineole (27.23%), α-pinene (19.43%) and β-pinene (6.71%) were evaluated for their in vitro antibacterial activities and toxicology properties. R. officinalis L. essential oil possessed similar antibacterial activities to α-pinene, and a little bit better than β-pinene, while 1,8-cineole possessed the lowest antibacterial activities. R. officinalis L. essential oil exhibited the strongest cytotoxicity towards three human cancer cells. Its inhibition concentration 50% (IC50) values on SK-OV-3, HO-8910 and Bel-7402 were 0.025‰, 0.076‰ and 0.13‰ (v/v), respectively. The cytotoxicity of all the test sampl…
Novel Analogs and Stereoisomers of the Marine Toxin Neodysiherbaine with Specificity for Kainate Receptors
2007
Antagonists for kainate receptors (KARs), a family of glutamategated ion channels, are efficacious in a number of animal models of neuropathologies, including epilepsy, migraine pain, and anxiety. To produce molecules with novel selectivities for kainate receptors, we generated three sets of analogs related to the natural marine convulsant neodysiherbaine (neoDH), and we characterized their pharmacological profiles. Radioligand displacement assays with recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and KARs demonstrated that functional groups at two positions on the neoDH molecule are critical pharmacological determinants; only binding to the glutamate receptor …
The Functional Renormalization Group
2018
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The amazing graphene: an educational bridge connecting different Physics concepts
2017
The purpose of this work is to present a learning workshop covering various physics concepts aimed at strengthening physics/engineering student understanding about the remarkable properties of two dimensional materials, graphene in particular. At the basis of this learning experience is the idea of blending and interconnecting separate pieces of knowledge already acquired by undergraduates in different courses and to help them visualize and link the concepts lying beyond separate chunks of information or equations. Graphene represents an appropriate unifying framework to achieve this task in view of its monatomic structure and various exotic processes peculiar to this and some other two dim…
Measurement with the ATLAS detector of multi-particle azimuthal correlations in p+Pb collisions at sNN=5.02 TeV
2013
In order to study further the long-range correlations ("ridge") observed recently in p + Pb collisions at root s(NN) = 5.02 TeV, the second-order azimuthal anisotropy parameter ofcharged particles, ...
Theory of Computation, Fuzziness and a physics of the immaterial
2013
In this paper we advance three clear-cut proposals as a contribution to the discussion on the role of notions of Computation and Fuzziness as a bridge between Hard and Soft Sciences. We suggest that an important difference between the two great fami- lies of science lies in their subject or research having a grounding in nature or not, and that Theory of Computation is a glaring exception to this classifi- cation, being a textbook hard science but dealing with the immaterial. We further advance that such unicity is strongly connected with Church-Turing thesis, and discuss about the role of Computation and Fuzziness as pillars of immaterial sciences