Search results for "Rini"

Endoskopische Diagnostik und Therapie der akuten biliären Pankreatitis

1987

Endoskopische retrograde Cholangiopankreatikographie (ERCP) und endoskopische Papillometrie (EPT) sind wesentliche Saulen der Diagnostik und Therapie der akuten biliaren Pankreatitis. Patienten mit Pankreatitis sowie klinischen und laborchemischen Hinweisen auf eine extrahepatische Cholestase sollten unbedingt endoskopiert werden. Die EPT ermoglicht eine effektive und komplikationsarme Therapie, wenn die Pankreatitis mit Konkrementen in den Gallenwegen oder der Papille assoziert ist. Bei Patienten mit akuter Cholezystitis bei Cholezystolithiasis lassen sich mittels endoskopischer Manometrie funktionele Storungen der Papillenmotilitat nachweisen, die als Ursache von Cholestase und Pankreatit…

L’efficacia del trinitrato di glicerina allo 0,2% per uso topico nel ridurre il dolore post- emorroidectomia e favorire la guarigione delle ferite

2005

The aim of the study was to evaluate whether topical application of 0.2% glyceryl trinitrate ointment could reduce post-haemorrhoidectomy healing time and pain both at rest and during defecation. Thirty patients with grade III and IV haemorrhoids were included in the study and divided into two groups. All patients underwent Milligan-Morgan haemorrhoidectomy, and anorectal manometry was performed before surgery and after 5 and 30 days. In one group a placebo ointment was applied to the perianal wounds, while in the other group a 0.2% glyceryl trinitrate ointment was used. Maximum resting pressure was reduced in the glyceryl trinitrate group and increased in the placebo group after 5 days. Po…

Breeding-related seasonal changes in immunocompetence, health state and condition of the cyprinid fish, Rutilus rutilus, L.

2003

Seasonal changes in immunocompetence are predicted by the hypothesized trade-off between reproduction and self-maintenance, whereby immune function is a measure of self-maintenance and reproductive effort is seasonally dependent. We examined seasonal patterns in immunological, haematological and body condition parameters for male and female freshwater fish. In two different populations, the relative size of the spleen and the chemotaxic migration activity of head kidney granulocytes decreased immediately before and after spawning, respectively. Those decreases were accompanied by an increase in haematocrit values shortly before and after spawning in both populations and a decrease in the re…

Taxonomic review of the fungal-inhabiting plant bug genera Bothriomiris and Dashymenia (Hemiptera: Heteroptera: Miridae: Cylapinae: Bothriomirini), w…

2016

The two closely related and frequently confused genera of the fungal-inhabiting plant bug subfamily Cylapinae, Bothriomiris Kirkaldy, 1902 and Dashymenia Poppius, 1910 are redefined and reviewed. Two new species of Dashymenia, D. artchawakomi, new species and D. gorczycai, new species, are described from Thailand. Bothriomiris capillosus Yasunaga, 2000 and B. yakushima Yasunaga & Miyamoto, 2012 are transferred to the genus Dashymenia Poppius, and a revised key to the two genera is provided. Color habitus images of the adults are given for Dashymenia artchawakomi, D. capillosa, and D. gorczycai. The male genitalic structures of the following species are illustrated: Bothriomiris ernsti Yasun…

A New Method to Reconstruct Quantitative Food Webs and Nutrient Flows from Isotope Tracer Addition Experiments

2020

Understanding how nutrients flow through food webs is central in ecosystem ecology. Tracer addition experiments are powerful tools to reconstruct nutrient flows by adding an isotopically enriched element into an ecosystem and tracking its fate through time. Historically, the design and analysis of tracer studies have varied widely, ranging from descriptive studies to modeling approaches of varying complexity. Increasingly, isotope tracer data are being used to compare ecosystems and analyze experimental manipulations. Currently, a formal statistical framework for analyzing such experiments is lacking, making it impossible to calculate the estimation errors associated with the model fit, the…

Reduction of clozapine-induced hypersalivation by pirenzepine is safe.

2004

Introduction Hypersalivation is known as a frequent, disturbing, and socially stigmatizing side effect of therapy with the atypical antipsychotic clozapine. It has been shown that the addition of the anticholinergic pirenzepine is able to reduce clozapine-induced hypersalivation, probably by blocking M4-receptors. Nevertheless, a pharmacokinetic interaction between both compounds cannot be excluded. Methods In this pilot study, 29 schizophrenic patients (ICD-10; 51.7 % female; age: 36.7 +/- 8.7 years [mean +/- SD]) were included. Serum concentrations of clozapine and its pharmacologically active metabolite N-desmethylclozapine were determined under steady-state conditions by automated HPLC …

Tetrathiafulvalene-Capped Hybrid Materials for the Optical Detection of Explosives

2013

[EN] Mesoporous silica microparticles capped with TTF moieties and containing a ruthenium dye in the pores were used for the turn-on optical detection of the nitroaromatic explosives Tetryl and TNT via a selective pore uncapping and release of the entrapped dye.

In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.

2007

The objective was to devise and apply a novel modelling approach to combine segmental in situ rat perfusion data and in vitro cell culture data, in order to elucidate the contribution of efflux in drug absorption kinetics. The fluoroquinolone CNV97100 was used as a model P-gp substrate. In situ intestinal perfusion was performed in rat duodenum, jejunum, ileum and colon to measure the influence of P-gp expression on efflux. Inhibition studies of CNV97100 were performed in the presence of verapamil, quinidine, cyclosporin A and p-aminohippuric acid. Absorption/efflux parameters were modelled simultaneously, using data from both in situ studies as well as in vitro studies. The maximal efflux …

Domain shuffling between Vip3Aa and Vip3Ca: chimera stability and insecticidal activity against European, American, African, and Asian pests

2020

The bacterium Bacillus thuringiensis produces insecticidal Vip3 proteins during the vegetative growth phase with activity against several lepidopteran pests. To date, three different Vip3 protein families have been identified based on sequence identity: Vip3A, Vip3B, and Vip3C. In this study, we report the construction of chimeras by exchanging domains between Vip3Aa and Vip3Ca, two proteins with marked specificity differences against lepidopteran pests. We found that some domain combinations made proteins insoluble or prone to degradation by trypsin as most abundant insect gut protease. The soluble and trypsin-stable chimeras, along with the parental proteins Vip3Aa and Vip3Ca, were tested…

2021

Muscarinic acetylcholine receptors (mAChRs) belong to the superfamily of G-protein-coupled receptors (GPCRs). The family of mAChRs is composed of five subtypes, M1, M2, M3, M4 and M5, which have distinct expression patterns and functions. In the eye and its adnexa, mAChRs are widely expressed and exert multiple functions, such as modulation of tear secretion, regulation of pupil size, modulation of intraocular pressure, participation in cell-to-cell signaling and modula-tion of vascular diameter in the retina. Due to this variety of functions, it is reasonable to assume that abnormalities in mAChR signaling may contribute to the development of various ocular diseases. On the other hand, mAC…