Search results for "Rini"

showing 10 items of 746 documents

Cellular Acetylcholine Receptor Expression in the Brain of Patients with Alzheimer’s and Parkinson’s Dementia

1995

Binding studies and receptor autoradiography reveal the overall changes of acetylcholine receptors (AChR) in Alzheimer’s and Parkinson’s dementia cortices.2,5 A detailed account of these changes requires a study of neurochemical phenotype of individual neurons as basic elements of networks constituting the substrate of cortical functions.4 Examples will be given for cell-type specific AChR localization in normal and diseased human cerebral cortex.

business.industrymedicine.diseasePhenotypemedicine.anatomical_structureNeurochemicalCerebral cortexMuscarinic acetylcholine receptorMedicineDementiasense organsbusinessReceptorNeuroscienceAcetylcholine receptor
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Novel concepts on the recovery of by-products from alkaline pulping

2016

Innovative biorefinery concepts were developed for the separation and utilization of organic materials, especially aliphatic carboxylic acids, lignin, and extractives, which are formed as by-products during wood-based alkaline delignification processes. The partial recovery of sodium as NaOH and aliphatic carboxylic acids from hardwood soda-AQ black liquor was studied via electrodialysis. The lignin was partly (about 59 % of the initial lignin) precipitated from black liquor by carbonation (pH to about 8.5) followed by electrodialysis or H2SO4 (pH to about 2), with subsequent precipitation of more lignin and the liberation of aliphatic acids. The Na2SO4 formed was successfully separated fro…

carbonationesteritkarboksyylihapotmäntyöljyaliphatic carboxylic acidsrasvahapotfood and beveragesligninselluligniiniblack liquormustalipeätall oil fatty acidscomplex mixturesalifaattiset yhdisteetacidificationestersglucoisosaccharinic acidtalteenottoselluteollisuussivutuotteetnatriumelektrodialyysielectrodialysishappokäsittely
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Le gallerie VIII e IX: analisi strutturale. Le lucerne. Elementi del corredo personale

2007

The paper reports the results of the archaeological excavations carried out between 2000 and 2007 in the Early Christian cemetery of Villagrazia di Carini. Four periods were recognized in stratigraphy, from late antiquity to the mid-twentieth century. The sepulchral typologies are arcosolia, loculi, "tombe a mensa" and "formae". The cemetery was used by the Christian community of the ancient diocese of Hykkara from the 4th to at least the 7th century A.D.

catacombaEarly Christian cemeteryarcosolia.HyccarastratigraphyVillagrazia di CariniSettore L-ANT/08 - Archeologia Cristiana E Medievalearchaeological excavationanalisi strutturale
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Catacomba di Villagrazia di Carini. La galleria XII: indagini archeologiche e problemi della conservazione

2017

The archaeological research in the southeastern area of the Early Christian catacombs of Villagrazia di Carini has been ongoing since 2000 to the present, but in 2014 the structural problems occurred during the excavation of the cubicles X13 and X15 have showed that this sector of the cemetery was cut into a tuff stone bench less compact and durable than the rest of the catacomb. Similarly, the excavation in the corridor XII has provided new informations about the serious effects of the physico-chemical changes that occurred here, over the centuries, by the action of the environmental factors and the continued infiltrations of water from the above ground. The risk of a collapse that would m…

catacombs Villagrazia di Carini tombe a mensa loculi cubicles archaeological stratigraphy alteration processes detachments deterioration state of conservation.conservazioneCatacomba paleocristianadegrado strutturalespazi funerari privatiVillagrazia di Carinicimitero comunitariostratigrafia.consolidamentoSettore L-ANT/08 - Archeologia Cristiana E Medievale
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Design, Synthesis, and Use of Y-Shaped ATRP/NMP Surface Tethered Initiator.

2015

Heterogeneous polymer brushes on surfaces can be easily formed from a binary initiator on a silicon oxide substrate where two different types of polymers can be grown side-by-side. Herein, we designed a new Y-shaped binary initiator using straightforward chemistry for “grafting from” polymer brushes. This initiator synthesis takes advantage of the Passerini reaction, a multicomponent reaction combining two initiator sites and one surface linking site. This Y-shaped binary initiator can be synthesized in three steps with a higher yield than other similar initiators reported in the literature, and can be performed on a multigram scale. We were able to attach the initiator to a silicon oxide s…

chemistry.chemical_classificationMaterials sciencePolymers and PlasticsBulk polymerizationOrganic Chemistryfood and beveragesSubstrate (electronics)PolymerGraftingPasserini reactionInorganic ChemistryContact anglechemistryYield (chemistry)Polymer chemistryMaterials ChemistrySilicon oxideACS macro letters
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Biopartitioning micellar chromatography: An alternative high-throughput method for assessing the ecotoxicity of anilines and phenols

2007

An investigation of the use of the chromatographic retention (log k) as an in vitro approach for modelling the toxicity to Fathead Minnows of anilines and phenols is developed. A data set of 65 compounds with available experimental toxicity data was used. Log k data at three pH values were used for the compounds classification and two groups or 'MODEs' were identified. For one 'MODE' a quantitative retention-activity relationship (QRAR) model was calculated. Finally, it was used to estimate the toxicity to Fathead minnows of anilines and phenols for which experimental data are not available. These estimations were compared to those obtained from another toxicity (to Tetrahymena pyriformis) …

chemistry.chemical_classificationQuantitative structure–activity relationshipAniline CompoundsChromatographyToxicity dataTetrahymena pyriformisClinical BiochemistryCyprinidaeQuantitative Structure-Activity RelationshipAromatic amineExperimental dataCell BiologyGeneral MedicineBiochemistryAnalytical Chemistrychemistry.chemical_compoundPhenolschemistryTetrahymena pyriformisToxicityAnimalsSpectrophotometry UltravioletPhenolsEcotoxicityChromatography Micellar Electrokinetic CapillaryJournal of Chromatography B
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Experimental organic matter maturation at 2kbar: Heat-up effect to low temperatures on vitrinite reflectance

2012

Abstract An experimental study was performed to evaluate the effect of heat-up to various low temperatures on vitrinite reflectance ( VR ) at 2 kbar employing the same previously used heat-up procedures, starting material and apparatus. Heat-up is the isobaric experimental procedure consisting of the increase in temperature of the laboratory vitrinite maturation from room temperature to the desired run temperature T end of heat-up at which the isobaric-isothermal maturation starts. Experiments employed cold-seal pressure vessels with classical heat-up devices and were carried out on wet (water added) xylite of swamp cypress. Confined system maturation experiments were conducted at 2 kbar an…

chemistry.chemical_classificationVitrinite reflectance020209 energyStratigraphyKinetic analysisThermodynamicsMineralogyGeology02 engineering and technologyRate equation010502 geochemistry & geophysicsKinetic energy01 natural sciencesIsothermal processFuel Technologychemistry0202 electrical engineering electronic engineering information engineeringIsobaric processEconomic GeologyOrganic matterVitrinite0105 earth and related environmental sciencesInternational Journal of Coal Geology
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Acetylcholine receptors (muscarinic) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

2019

Muscarinic acetylcholine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [45]) are GPCRs of the Class A, rhodopsin-like family where the endogenous agonist is acetylcholine. In addition to the agents listed in the table, AC-42, its structural analogues AC-260584 and 77-LH-28-1, N-desmethylclozapine, TBPB and LuAE51090 have been described as functionally selective agonists of the M1 receptor subtype via binding in a mode distinct from that utilized by non-selective agonists [243, 242, 253, 155, 154, 181, 137, 11, 230]. There are two pharmacologically characterised allosteric sites on muscarinic receptors, one defined by it binding gallami…

chemistry.chemical_compoundChemistryAllosteric regulationMuscarinic acetylcholine receptormedicineStrychnineMuscarinic acetylcholine receptor M1PharmacologyAcetylcholineEndogenous agonistmedicine.drugAcetylcholine receptorG protein-coupled receptorIUPHAR/BPS Guide to Pharmacology CITE
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ChemInform Abstract: Synthesis and Muscarinic Activity of Isoxazole-Substituted 1,2,5,6- Tetrahydropyridines.

2010

chemistry.chemical_compoundChemistryStereochemistryMuscarinic acetylcholine receptorGeneral MedicineIsoxazoleChemInform
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ChemInform Abstract: Design and Pharmacology of Quinuclidine Derivatives as M2-Selective Muscarinic Receptor Ligands.

2010

chemistry.chemical_compoundChemistryStereochemistryMuscarinic acetylcholine receptorGeneral MedicineQuinuclidineChemInform
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