Search results for "Risk Analysi"
showing 10 items of 380 documents
Comparison between two different cardiovascular models during a hemorrhagic shock scenario
2020
Hemorrhagic shock is a form of hypovolemic shock determined by rapid and large loss of intravascular blood volume and represents the first cause of death in the world, whether on the battlefield or in civilian traumatology. For this, the ability to prevent hemorrhagic shock remains one of the greatest challenges in the medical and engineering fields. The use of mathematical models of the cardiocirculatory system has improved the capacity, on one hand, to predict the risk of hemorrhagic shock and, on the other, to determine efficient treatment strategies. In this paper, a comparison between two mathematical models that simulate several hemorrhagic scenarios is presented. The models considere…
Lateral flow assays towards point-of-care cancer detection: A review of current progress and future trends
2020
Abstract Cancer is one of the main causes of mortality and morbidity worldwide. However, its early non-invasive detection via quantification of appropriate biomarkers can significantly reduce mortality, enhance survival, and save treatment costs. Lateral flow test strips (LFTS) are nowadays considered as the most attractive point-of-care devices for healthcare applications. However, the quantification of cancer biomarkers in body fluids suffers from some challenges including i) the necessity for multiplex analysis, ii) the development of sensitive detection systems, iii) to overcome the analysis of complex samples, at the same time, it should keep the quality assurance criteria for an accur…
Hemoglobin point-of-care testing: the HemoCue system.
2013
Besides the use of traditional laboratory resources, the diagnosis of anemia can also be accomplished by assessing hemoglobin (Hb) concentration with point-of-care testing (POCT) devices such as the HemoCue test systems. In several situations, these devices might suitably replace traditional laboratory testing, including several areas of health care where a very rapid Hb measurement might be required to make immediate therapeutic decisions. The use of these devices, however, should fulfill some basic criteria, including economic, clinical, and regulatory issues; appropriate training of the users and knowledge of test requirements, performance, limitations, and potential interferences; the u…
Exploiting 3D Modelling and Life Cycle Assessment to Improve the Sustainability of Pavement Management
2020
Today road agencies worldwide face difficult decisions for construction, maintenance and rehabilitation of their road infrastructure as they try to balance limited budgets. This is further complicated rising environmental concerns over equipment and techniques used for these practices. This has led agencies to consider alternative approaches for smarter and sustainable pavement asset management systems. This paper considers the use of a low-cost 3D image modelling distress identification and classification proposal for data acquisition and analysis. To establish its environmental friendliness, a case study in Palermo, Italy, is considered wherein a Life Cycle Assessment (LCA) exercise is do…
Food safety risk analysis from the producers' perspective: prioritisation of production process stages by HACCP and TOPSIS
2018
[EN] From the manufacturers perspective, the Hazard Analysis and Critical Control Point (HACCP) system nowadays represents the mainly way to implement the food safety risk management in food industries. Nevertheless, the identification and prioritization of hazards as the outcome of the first principle of HACCP is not sufficient to identify production process stages that more significantly and critically contribute to the consumer¿s risks. With this recognition, the present paper proposes a Quantitative Risk Assessment (QRA) approach based on HACCP and Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) to individuate production process phases on which implementing co…
The new world of human genetic technologies: The policy environment and impacts of genetic screening tests
1995
Today it is possible to screen for mutated DNA sequences which do not induce any diseases but predispose to develop diseases under certain environmental condition. These latter disorders are called “multifactorial” since they result from the interplay of genetic and environmental factors. Among multifactorial disorders there are job-related diseases whose genetic component can be identified by genetic screening tests. The use of these tests to predict occupational disorders, to cut down on them, and to save costs—in particular for absenteeism, health care, and lawsuits—is of interest to employers and insurers. As for employees, it could entail an extremely deep invasion of privacy, economic…
Planning for an environment-friendly car
2000
During the process of developing a new product, consciously or unconsciously, a number of decisions are made that affect the environment, thus making a company responsible not only for the technical performance but also for the “environmental performance” of a product. This research paper broadly speaks about this development process and lists the various tools available to the modern decision maker for balancing the ecological, economical and technological aspects of production. The focus of this paper is on the environmental issues in the automobile industry and environmental impacts presently associated with the automobile life cycle. The paper reviews existing tools and opportunities fo…
Progress in analysis of residual antibacterials in food
2007
Abstract Residual antibacterials in food constitute a risk to human health. Although epidemiological data on the real magnitude of their adverse effects are very scarce, they indicate that food could be an important avenue for evolution and dissemination of antibiotic-resistant bacteria. Analysis of these residues plays a key role in ensuring food safety, to the point that the European Union has not only established maximum residue limits but also requirements concerning the performance of analytical methods and the interpretation of the results. These specifications have had a great influence on protocols and techniques applied. In this review, we discuss the progress of rapid screening me…
IS evolution benefit assessment: Challenges with economic investment criteria
2007
Maintenance and system evolution activities have a significant role in the information system (IS) life cycle. It has been estimated that approximately 80% of the total IT expenses are allocated for maintenance activities [20]. According to Lehman’s first law, maintenance is necessary, because software needs to be continuously improved or it will get out of date and cannot respond to the requirements of its environment [19]. Despite the importance of IS evolution investments, there is a gap between the IT related costs and company profitability [27]. Brynjolfssen [10] described this as a productivity paradox: information technology utilization has increased since the 70’s but simultaneously…
A Cooperative Multi-Agent System for Crowd Sensing Based Estimation in Smart Cities
2020
The concept of Smart City has spread as a solution to ensure better access to information and services to citizens, but also as a means to reduce the environmental footprint of cities. To this end, a continuous and wide observation of the environment is necessary to analyze information that enables government bodies to act on the environment appropriately. Moreover, a diffused acquisition of information requires adequate infrastructure and proper devices, which results in relevant installation and maintenance costs. Our proposal enables reducing the number of necessary sensors to be deployed while ensuring that information is available at any time and anywhere. We present the HybridIoT syst…