Search results for "Risk analysis"
showing 10 items of 375 documents
Technological advancements in the analysis of human motion and posture management through digital devices
2021
Technological development of motion and posture analyses is rapidly progressing, especially in rehabilitation settings and sport biomechanics. Consequently, clear discrimination among different measurement systems is required to diversify their use as needed. This review aims to resume the currently used motion and posture analysis systems, clarify and suggest the appropriate approaches suitable for specific cases or contexts. The currently gold standard systems of motion analysis, widely used in clinical settings, present several limitations related to marker placement or long procedure time. Fully automated and markerless systems are overcoming these drawbacks for conducting biomechanical…
Designing disease-resistant crops : from basic knowledge to biotechnology
2020
Ancient records describe how plant diseases were attributed to many causes which included divine power, religious belief, and superstition. Far from these days, we now have detailed knowledge about how plant immunity is executed. Plants employ two types of sensors to perceive and defeat the litany of pathogenic organisms that attack them, whilst microbes deploy a myriad of specialized weapons to suppress immunity and promote infection. This opens a path to exploiting these insights to increase crop resistance. Here we describe novel biotechnological approaches for designing superior disease-resistant crops to fight agricultural losses in the field while reducing chemical inputs, towards a m…
Probabilities in Risk Management
2014
A project is generally a complex undertaking in which most things are uncertain (durations, costs, project and suppliers performance, weather, soil geology, public reaction, etc.), and thus, risk permeates everything. Risk is closely related to uncertainty, and the latter with probabilities and distributions the conceptual aspects of which are explained in Chap. 9. It is inconceivable to address risk without considering probabilities of occurrence, and the measures that must be taken to prevent or mitigate risk; in that sense, the ‘buffer’ concept is introduced. In Chap. 2, a comparison was mentioned between CPM, PERT and MC; now, Chap. 3 proposes a case for numerically demonstrating the ad…
Project During Execution – Strategy – Updating
2014
This chapter fundamentally examines project performance during its execution period, however, risk must always be considered, especially at the very beginning of the project when the risk is normally maximum, and at each update. In the Project Monitoring stage, this chapter explores what happens with foreseen risks, that is, if they really happened or not and their consequences. In the Project Control stage, the chapter uses Earned Value Analysis and examines Performance Factors, which are used to predict completion regarding time and cost. However, because these calculations are based on past performance, there is always the risk that this performance will not be replicated in the future, …
Recurrence of hepatocellular carcinoma after direct acting antiviral treatment for hepatitis C virus infection: Literature review and risk analysis
2018
Although studies suggest decreased incident hepatocellular carcinoma (HCC) after treatment with direct-acting antivirals (DAAs) for hepatitis C virus (HCV) infection, data are conflicting regarding risk and aggressiveness of recurrence in patients who have a history of treated HCC. This review analyses data available in literature in order to elucidate the impact of DAAs on the risk of HCC recurrence after successful treatment of the tumor. Overall 24 papers were identified. The available data cannot be considered definitive, but the initial alarmist data indicating an increased risk of recurrence have not been confirmed by most subsequent studies. The suggested aggressive pattern (rapid gr…
Predicting survival in node-positive prostate cancer after open, laparoscopic or robotic radical prostatectomy: A competing risk analysis of a multi-…
2016
Objectives: To investigate cancer-specific mortality and other-cause mortality in prostate cancer patients with nodal metastases. Methods: The study included 411 patients treated with radical prostatectomy and pelvic lymph node dissection for prostate cancer with lymph node metastases at 10 tertiary care centers between 1995 and 2014. Kaplan–Meier analyses were used to assess cancer-specific mortality-free survival rates at 8 years' follow up in the overall population, and after stratifying patients according to clinical and pathological parameters. Uni- and multivariable competing risk Cox regression analyses were used to assess cancer-specific mortality and other-cause mortality. Finally,…
The EndoPredict Gene-Expression Assay in Clinical Practice - Performance and Impact on Clinical Decisions
2013
The validated EndoPredict assay is a novel tool to predict the risk of metastases of patients with estrogen receptor positive, HER2 negative breast cancer treated with endocrine therapy alone. It has been designed to integrate genomic and clinical information and includes clinico-pathological factors such as tumor size and nodal status. The test is feasible in a decentral setting in molecular pathology laboratories. In this project, we investigated the performance of this test in clinical practice, and performed a retrospective evaluation of its impact on treatment decisions in breast cancer. During one year, EndoPredict assays from 167 patients could be successfully performed. For retrospe…
Ontological information system for the selection of technologies for the treatment and disposal of organic waste: engineering and educational aspects
2021
The article proves a problem of information processing in the field of the structuring of information and decision-making in environmental engineering, including education in this field. This article presents the ontology-information model that was used to systematize waste treatment equipment. The article presents the use of an ontological algorithm “Polyhedron” for engineers and teachers. The algorithm consists of integrating ontological solutions from abstract to specific. The proposed model consists of a general ontology of “waste treatment technologies selection”, “waste treatment equipment selection” and “Ontology for the analysis of scientific publications”. Users of the system can i…
Disentangling the Process of Work–Family Conflict
2016
Abstract. The purpose of this conceptual article is to deliver a new framework model for research on work–family conflict (WFC), which overcomes existing limitations. By adopting an organizational stress perspective on WFC we show that WFC should be conceptualized as a process. By disentangling its components we point out several problems of WFC research and how our new approach can help to avoid them. Research on WFC often does not comply with the current standards of organizational stress research. Common WFC measures bear the potential of content that overlaps with determinants and outcomes, which might spuriously inflate correlations. To avoid measurement overlap, we propose to operati…
Spatial risks and complex systems: methodological perspectives
2007
Research on risk and industrial catastrophes question the complexity theories. Besides the concepts of complexity which lead us to reconsider concepts of risk, hazard and vulnerability, we propose to think about more practical aspects, for example the modelling of human behaviour in crisis situations. The link between concepts as critical self-organization, emergence, bifurcation, and the methods in the Distributed Artificial Intelligence (DAI) used to model them is however difficult. In this paper, we present ongoing analysis on the key concepts of risk science, such as hazards and catastrophes. We propose to enrich them with complex systems theories. First, we present methodological persp…